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Volumn 63, Issue 6, 2014, Pages 2051-2062

Induction of mixed chimerism depletes pre-existing and de novo-developed autoreactive B cells in autoimmune NOD mice

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; INSULIN ANTIBODY;

EID: 84901362128     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1532     Document Type: Article
Times cited : (9)

References (49)
  • 1
    • 80051744661 scopus 로고    scopus 로고
    • Type 1 diabetes immunotherapy: Is the glass half empty or half full?
    • Herold KC, Bluestone JA. Type 1 diabetes immunotherapy: is the glass half empty or half full? Sci Transl Med 2011;3:fs1
    • (2011) Sci Transl Med , vol.3
    • Herold, K.C.1    Bluestone, J.A.2
  • 2
    • 0035511862 scopus 로고    scopus 로고
    • International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: Identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice
    • Bonifacio E, Atkinson M, Eisenbarth G, et al. International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice. Diabetes 2001;50:2451-2458
    • (2001) Diabetes , vol.50 , pp. 2451-2458
    • Bonifacio, E.1    Atkinson, M.2    Eisenbarth, G.3
  • 3
    • 0029826977 scopus 로고    scopus 로고
    • B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" stock of NOD.Ig mu null mice
    • Serreze DV, Chapman HD, Varnum DS, et al. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J Exp Med 1996;184:2049- 2053
    • (1996) J Exp Med , vol.184 , pp. 2049-2053
    • Serreze, D.V.1    Chapman, H.D.2    Varnum, D.S.3
  • 4
    • 8544271680 scopus 로고    scopus 로고
    • Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in nonobese diabetic mice
    • Akashi T, Nagafuchi S, Anzai K, et al. Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in nonobese diabetic mice. Int Immunol 1997;9:1159-1164
    • (1997) Int Immunol , vol.9 , pp. 1159-1164
    • Akashi, T.1    Nagafuchi, S.2    Anzai, K.3
  • 5
    • 0030969531 scopus 로고    scopus 로고
    • B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice
    • Noorchashm H, Noorchashm N, Kern J, Rostami SY, Barker CF, Naji A. B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice. Diabetes 1997;46:941-946
    • (1997) Diabetes , vol.46 , pp. 941-946
    • Noorchashm, H.1    Noorchashm, N.2    Kern, J.3    Rostami, S.Y.4    Barker, C.F.5    Naji, A.6
  • 6
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
    • Serreze DV, Fleming SA, Chapman HD, Richard SD, Leiter EH, Tisch RM. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Immunol 1998;161: 3912-3918
    • (1998) J Immunol , vol.161 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 7
    • 0032145276 scopus 로고    scopus 로고
    • B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice
    • Falcone M, Lee J, Patstone G, Yeung B, Sarvetnick N. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice. J Immunol 1998;161:1163- 1168
    • (1998) J Immunol , vol.161 , pp. 1163-1168
    • Falcone, M.1    Lee, J.2    Patstone, G.3    Yeung, B.4    Sarvetnick, N.5
  • 8
    • 0035176817 scopus 로고    scopus 로고
    • B lymphocytes not required for progression from insulitis to diabetes in non-obese diabetic mice
    • Charlton B, Zhang MD, Slattery RM. B lymphocytes not required for progression from insulitis to diabetes in non-obese diabetic mice. Immunol Cell Biol 2001;79:597-601
    • (2001) Immunol Cell Biol , vol.79 , pp. 597-601
    • Charlton, B.1    Zhang, M.D.2    Slattery, R.M.3
  • 9
    • 77954232248 scopus 로고    scopus 로고
    • Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene
    • Kendall PL, Moore DJ, Hulbert C, Hoek KL, Khan WN, Thomas JW. Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene. J Immunol 2009;183:6403- 6412
    • (2009) J Immunol , vol.183 , pp. 6403-6412
    • Kendall, P.L.1    Moore, D.J.2    Hulbert, C.3    Hoek, K.L.4    Khan, W.N.5    Thomas, J.W.6
  • 11
    • 43049171493 scopus 로고    scopus 로고
    • B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype- specific differences in Fc gamma R effector functions
    • Xiu Y, Wong CP, Bouaziz JD, et al. B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype- specific differences in Fc gamma R effector functions. J Immunol 2008;180: 2863-2875
    • (2008) J Immunol , vol.180 , pp. 2863-2875
    • Xiu, Y.1    Wong, C.P.2    Bouaziz, J.D.3
  • 12
    • 58149359257 scopus 로고    scopus 로고
    • Targeting CD22 reprograms B-cells and reverses autoimmune diabetes
    • Fiorina P, Vergani A, Dada S, et al. Targeting CD22 reprograms B-cells and reverses autoimmune diabetes. Diabetes 2008;57:3013-3024
    • (2008) Diabetes , vol.57 , pp. 3013-3024
    • Fiorina, P.1    Vergani, A.2    Dada, S.3
  • 13
    • 80755168884 scopus 로고    scopus 로고
    • Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies
    • Serreze DV, Chapman HD, Niens M, et al. Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies. Diabetes 2011;60:2914-2921
    • (2011) Diabetes , vol.60 , pp. 2914-2921
    • Serreze, D.V.1    Chapman, H.D.2    Niens, M.3
  • 14
    • 70449480577 scopus 로고    scopus 로고
    • Et al.; Type 1 Diabetes TrialNet Anti-CD20 Study Group. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function
    • Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, et al.; Type 1 Diabetes TrialNet Anti-CD20 Study Group. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N Engl J Med 2009;361:2143-2152
    • (2009) N Engl J Med , vol.361 , pp. 2143-2152
    • Pescovitz, M.D.1    Greenbaum, C.J.2    Krause-Steinrauf, H.3
  • 15
    • 84893118586 scopus 로고    scopus 로고
    • B-lymphocyte depletion with rituximab beta-cell function two-year results
    • Type 1 Diabetes TrialNet Anti-CD20 Study Group
    • Pescovitz MD, Greenbaum CJ, Bundy B, et al.; Type 1 Diabetes TrialNet Anti-CD20 Study Group. B-lymphocyte depletion with rituximab and beta-cell function: two-year results. Diabetes Care 2014;37:453-459
    • (2014) Diabetes Care , vol.37 , pp. 453-459
    • Pescovitz, M.D.1    Greenbaum, C.J.2    Et Al., B.B.3
  • 16
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody HOKT3gamma1 (Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • Herold KC, Gitelman SE, Masharani U, et al. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 2005;54:1763-1769
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3
  • 17
    • 84891715096 scopus 로고    scopus 로고
    • Therapeutic targeting of B cells and T cells in autoimmune diabetes: Is it a solution?
    • Chatenoud L. Therapeutic targeting of B cells and T cells in autoimmune diabetes: is it a solution? Diabetes 2013;62:2659-2661
    • (2013) Diabetes , vol.62 , pp. 2659-2661
    • Chatenoud, L.1
  • 18
    • 84883360314 scopus 로고    scopus 로고
    • Combination treatment with anti- CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes
    • Hu C, Ding H, Zhang X, Wong FS, Wen L. Combination treatment with anti- CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes. Diabetes 2013;62:2849-2858
    • (2013) Diabetes , vol.62 , pp. 2849-2858
    • Hu, C.1    Ding, H.2    Zhang, X.3    Wong, F.S.4    Wen, L.5
  • 19
    • 59649086980 scopus 로고    scopus 로고
    • Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI
    • Li N, Chen Y, He W, et al. Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI. Blood 2009;113:953-962
    • (2009) Blood , vol.113 , pp. 953-962
    • Li, N.1    Chen, Y.2    He, W.3
  • 21
    • 14944379043 scopus 로고    scopus 로고
    • + T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb
    • DOI 10.1182/blood-2004-06-2411
    • Liang Y, Huang T, Zhang C, et al. Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb. Blood 2005;105:2180-2188 (Pubitemid 40731811)
    • (2005) Blood , vol.105 , Issue.5 , pp. 2180-2188
    • Liang, Y.1    Huang, T.2    Zhang, C.3    Todorov, I.4    Atkinson, M.5    Kandeel, F.6    Forman, S.7    Zeng, D.8
  • 22
    • 79551595217 scopus 로고    scopus 로고
    • Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice
    • Racine J, Wang M, Zhang C, et al. Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice. Diabetes 2011;60: 555-564
    • (2011) Diabetes , vol.60 , pp. 555-564
    • Racine, J.1    Wang, M.2    Zhang, C.3
  • 23
    • 84860905305 scopus 로고    scopus 로고
    • Mixed chimerism and growth factors augment beta cell regeneration and reverse late-stage type 1 diabetes
    • Wang M, Racine JJ, Song X, et al. Mixed chimerism and growth factors augment beta cell regeneration and reverse late-stage type 1 diabetes. Sci Transl Med 2012;4:133ra59
    • (2012) Sci Transl Med , vol.4
    • Wang, M.1    Racine, J.J.2    Song, X.3
  • 24
    • 33846185996 scopus 로고    scopus 로고
    • + T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody
    • Zhang C, Lou J, Li N, et al. Donor CD8+ T cells mediate graft-versusleukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody. J Immunol 2007;178: 838-850 (Pubitemid 46095156)
    • (2007) Journal of Immunology , vol.178 , Issue.2 , pp. 838-850
    • Zhang, C.1    Lou, J.2    Li, N.3    Todorov, I.4    Lin, C.-L.5    Cao, Y.-A.6    Contag, C.H.7    Kandeel, F.8    Forman, S.9    Zeng, D.10
  • 26
    • 77956375584 scopus 로고    scopus 로고
    • Induction of chimerism permits lowdose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes
    • Zhang C, Wang M, Racine JJ, et al. Induction of chimerism permits lowdose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes. Diabetes 2010;59:2228-2236
    • (2010) Diabetes , vol.59 , pp. 2228-2236
    • Zhang, C.1    Wang, M.2    Racine, J.J.3
  • 27
    • 84862936227 scopus 로고    scopus 로고
    • Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease
    • Li X, Deng R, He W, et al. Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease. J Immunol 2012;188:724-734
    • (2012) J Immunol , vol.188 , pp. 724-734
    • Li, X.1    Deng, R.2    He, W.3
  • 28
    • 70449494642 scopus 로고    scopus 로고
    • Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
    • Yi T, Chen Y, Wang L, et al. Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood 2009;114:3101-3112
    • (2009) Blood , vol.114 , pp. 3101-3112
    • Yi, T.1    Chen, Y.2    Wang, L.3
  • 29
    • 52649136967 scopus 로고    scopus 로고
    • Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease
    • Yi T, Zhao D, Lin CL, et al. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood 2008;112: 2101-2110
    • (2008) Blood , vol.112 , pp. 2101-2110
    • Yi, T.1    Zhao, D.2    Lin, C.L.3
  • 30
    • 84862888262 scopus 로고    scopus 로고
    • Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease
    • Young JS, Wu T, Chen Y, et al. Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease. J Immunol 2012;189:222-233
    • (2012) J Immunol , vol.189 , pp. 222-233
    • Young, J.S.1    Wu, T.2    Chen, Y.3
  • 31
    • 33645505721 scopus 로고    scopus 로고
    • Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations
    • Zhang C, Todorov I, Zhang Z, et al. Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations. Blood 2006;107:2993-3001
    • (2006) Blood , vol.107 , pp. 2993-3001
    • Zhang, C.1    Todorov, I.2    Zhang, Z.3
  • 32
    • 52649147984 scopus 로고    scopus 로고
    • In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease
    • Zhao D, Zhang C, Yi T, et al. In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease. Blood 2008;112: 2129-2138
    • (2008) Blood , vol.112 , pp. 2129-2138
    • Zhao, D.1    Zhang, C.2    Yi, T.3
  • 34
    • 33646587068 scopus 로고    scopus 로고
    • Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouse
    • Tung JW, Mrazek MD, Yang Y, Herzenberg LA, Herzenberg LA. Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouse. Proc Natl Acad Sci USA 2006;103:6293-6298
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6293-6298
    • Tung, J.W.1    Mrazek, M.D.2    Yang, Y.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 35
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med 1991;173:1213-1225
    • (1991) J Exp Med , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 36
    • 77954153358 scopus 로고    scopus 로고
    • Absence of mature peripheral B cell populations in mice with concomitant defects in B cell receptor and BAFF-R signaling
    • Hoek KL, Carlesso G, Clark ES, Khan WN. Absence of mature peripheral B cell populations in mice with concomitant defects in B cell receptor and BAFF-R signaling. J Immunol 2009;183:5630-5643
    • (2009) J Immunol , vol.183 , pp. 5630-5643
    • Hoek, K.L.1    Carlesso, G.2    Clark, E.S.3    Khan, W.N.4
  • 38
    • 84888098197 scopus 로고    scopus 로고
    • Overexpression of TLR7 promotes cellintrinsic expansion and autoantibody production by transitional T1 B cells
    • Giltiay NV, Chappell CP, Sun X, et al. Overexpression of TLR7 promotes cellintrinsic expansion and autoantibody production by transitional T1 B cells. J Exp Med 2013;210:2773-2789
    • (2013) J Exp Med , vol.210 , pp. 2773-2789
    • Giltiay, N.V.1    Chappell, C.P.2    Sun, X.3
  • 39
    • 38749090153 scopus 로고    scopus 로고
    • Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
    • DOI 10.1084/jem.20071088
    • Meyer-Bahlburg A, Andrews SF, Yu KO, Porcelli SA, Rawlings DJ. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med 2008;205:155-168 (Pubitemid 351185723)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.1 , pp. 155-168
    • Meyer-Bahlburg, A.1    Andrews, S.F.2    Yu, K.O.A.3    Porcelli, S.A.4    Rawlings, D.J.5
  • 41
    • 11844260763 scopus 로고    scopus 로고
    • Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes
    • Acevedo-Suárez CA, Hulbert C, Woodward EJ, Thomas JW. Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes. J Immunol 2005;174:827-833 (Pubitemid 40094278)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 827-833
    • Acevedo-Suarez, C.A.1    Hulbert, C.2    Woodward, E.J.3    Thomas, J.W.4
  • 42
    • 84879621050 scopus 로고    scopus 로고
    • Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells
    • Wu T, Young JS, Johnston H, et al. Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells. J Immunol 2013;191:488-499
    • (2013) J Immunol , vol.191 , pp. 488-499
    • Wu, T.1    Young, J.S.2    Johnston, H.3
  • 43
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • DOI 10.1016/j.immuni.2004.05.010, PII S107476130400144X
    • Thien M, Phan TG, Gardam S, et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 2004;20:785-798 (Pubitemid 38757447)
    • (2004) Immunity , vol.20 , Issue.6 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3    Amesbury, M.4    Basten, A.5    Mackay, F.6    Brink, R.7
  • 44
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
    • DOI 10.1016/S1074-7613(04)00079-2, PII S1074761304000792
    • Lesley R, Xu Y, Kalled SL, et al. Reduced competitiveness of autoantigenengaged B cells due to increased dependence on BAFF. Immunity 2004;20:441- 453 (Pubitemid 38482122)
    • (2004) Immunity , vol.20 , Issue.4 , pp. 441-453
    • Lesley, R.1    Xu, Y.2    Kalled, S.L.3    Hess, D.M.4    Schwab, S.R.5    Shu, H.-B.6    Cyster, J.G.7
  • 45
    • 78049494232 scopus 로고    scopus 로고
    • BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling
    • Rowland SL, Leahy KF, Halverson R, Torres RM, Pelanda R. BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling. J Immunol 2010;185:4570-4581
    • (2010) J Immunol , vol.185 , pp. 4570-4581
    • Rowland, S.L.1    Leahy, K.F.2    Halverson, R.3    Torres, R.M.4    Pelanda, R.5
  • 48
    • 79960419023 scopus 로고    scopus 로고
    • Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments
    • Nikbakht N, Migone TS, Ward CP, Manser T. Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments. J Immunol 2011;187:37-46
    • (2011) J Immunol , vol.187 , pp. 37-46
    • Nikbakht, N.1    Migone, T.S.2    Ward, C.P.3    Manser, T.4
  • 49
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • DOI 10.1038/371389a0
    • Cyster JG, Hartley SB, Goodnow CC. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 1994; 371:389-395 (Pubitemid 24302553)
    • (1994) Nature , vol.371 , Issue.6496 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3


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