Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene

Journal of Immunology

Volumn 183, Issue 10, 2009, Pages 6403-6412

  Kendall, Peggy L ^a   Moore, Daniel J ^a   Hulbert, Chrys ^a   Hoek, Kristen L ^b   Khan, Wasif N ^b,c   Thomas, James W ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; BRUTON TYROSINE KINASE; IMMUNOGLOBULIN HEAVY CHAIN; INSULIN; INSULIN ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CELL FATE; CELL MATURATION; CONTROLLED STUDY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSGENE;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTE SUBSETS; DIABETES MELLITUS, TYPE 1; IMMUNE TOLERANCE; IMMUNOGLOBULIN HEAVY CHAINS; INSULIN; INSULIN ANTIBODIES; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; MUTATION; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; TRANSGENES;

EID: 77954232248     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900367     Document Type: Article

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