Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production

Journal of Immunology

Volumn 192, Issue 11, 2014, Pages 5118-5129

  O'Brien, Shaun ^a   Thomas, Rajan M ^b   Wertheim, Gerald B ^a,b   Zhang, Fuqin ^a   Shen, Hao ^a   Wells, Andrew D ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IKAROS TRANSCRIPTION FACTOR; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CANCER CONTROL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; HAPLOINSUFFICIENCY; IN VITRO STUDY; IN VIVO STUDY; INFECTION CONTROL; LISTERIOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; AUTOCRINE COMMUNICATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CLONAL ANERGY; IKAROS TRANSCRIPTION FACTOR; INTERLEUKIN-2; LISTERIOSIS; MELANOMA, EXPERIMENTAL; MICE; MICE, KNOCKOUT; UP-REGULATION;

EID: 84901268325     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301992     Document Type: Article

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