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Volumn 122, Issue 18, 2013, Pages 3149-3159

Transcriptional regulation of the Ikzf1 locus

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CIS ACTING ELEMENT; IKAROS TRANSCRIPTION FACTOR; IKZF1 PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 4; MYC PROTEIN; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2C; SPECIAL AT RICH SEQUENCE BINDING PROTEIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 7 LIKE 1; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR RUNX3; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; IKZF1 PROTEIN, HUMAN; ZFPN1A1 PROTEIN, MOUSE;

EID: 84888246827     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-01-474916     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 0030993348 scopus 로고    scopus 로고
    • Transcription factors required for lymphoid lineage commitment
    • Georgopoulos K. Transcription factors required for lymphoid lineage commitment. Curr Opin Immunol. 1997;9(2):222-227.
    • (1997) Curr Opin Immunol , vol.9 , Issue.2 , pp. 222-227
    • Georgopoulos, K.1
  • 2
    • 0032560018 scopus 로고    scopus 로고
    • Helios, a novel dimerization partner of ikaros expressed in the earliest hematopoietic progenitors
    • Kelley CM, Ikeda T, Koipally J, et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr Biol. 1998;8(9):508-515.
    • (1998) Curr Biol. , vol.8 , Issue.9 , pp. 508-515
    • Kelley, C.M.1    Ikeda, T.2    Koipally, J.3
  • 3
    • 14544287884 scopus 로고    scopus 로고
    • Ikaros-family proteins: In search of molecular functions during lymphocyte development
    • Cobb BS, Smale ST. Ikaros-family proteins: in search of molecular functions during lymphocyte development. Curr Top Microbiol Immunol. 2005; 290:29-47.
    • (2005) Curr Top Microbiol Immunol , vol.290 , pp. 29-47
    • Cobb, B.S.1    Smale, S.T.2
  • 4
    • 20244387299 scopus 로고    scopus 로고
    • Identification of flt31 lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson J, Månsson R, Buza-Vidas N, et al. Identification of Flt31 lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell. 2005;121(2):295-306.
    • (2005) Cell , vol.121 , Issue.2 , pp. 295-306
    • Adolfsson, J.1    Månsson, R.2    Buza-Vidas, N.3
  • 6
    • 33746906644 scopus 로고    scopus 로고
    • Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
    • Lai AY, Kondo M. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J Exp Med. 2006; 203(8):1867-1873.
    • (2006) J Exp Med , vol.203 , Issue.8 , pp. 1867-1873
    • Lai, A.Y.1    Kondo, M.2
  • 7
    • 64049102658 scopus 로고    scopus 로고
    • Genome-wide lineage-specific transcriptional networks underscore ikaros-dependent lymphoid priming in hematopoietic stem cells
    • Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 2009;30(4):493-507.
    • (2009) Immunity , vol.30 , Issue.4 , pp. 493-507
    • Ng, S.Y.1    Yoshida, T.2    Zhang, J.3    Georgopoulos, K.4
  • 8
    • 0028001362 scopus 로고
    • The ikaros gene is required for the development of all lymphoid lineages
    • Georgopoulos K, Bigby M, Wang JH, et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell. 1994;79(1):143-156.
    • (1994) Cell , vol.79 , Issue.1 , pp. 143-156
    • Georgopoulos, K.1    Bigby, M.2    Wang, J.H.3
  • 9
    • 0028866897 scopus 로고
    • A dominant mutation in the ikaros gene leads to rapid development of leukemia and lymphoma
    • Winandy S, Wu P, Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell. 1995;83(2):289-299.
    • (1995) Cell , vol.83 , Issue.2 , pp. 289-299
    • Winandy, S.1    Wu, P.2    Georgopoulos, K.3
  • 10
    • 78650213618 scopus 로고    scopus 로고
    • Alternative promoter usage at the notch1 locus supports ligand-independent signaling in t cell development and leukemogenesis
    • Gómez-del Arco P, Kashiwagi M, Jackson AF, et al. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity. 2010;33(5):685-698.
    • (2010) Immunity , vol.33 , Issue.5 , pp. 685-698
    • Gómez-Del Arco, P.1    Kashiwagi, M.2    Jackson, A.F.3
  • 11
    • 78650379575 scopus 로고    scopus 로고
    • Oncogenic activation of the notch1 gene by deletion of its promoter in ikaros-deficient T-all
    • Jeannet R, Mastio J, Macias-Garcia A, et al. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood. 2010;116(25):5443-5454.
    • (2010) Blood , vol.116 , Issue.25 , pp. 5443-5454
    • Jeannet, R.1    Mastio, J.2    Macias-Garcia, A.3
  • 12
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, Goorha S, Radtke I, et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature. 2007; 446(7137):758-764.
    • (2007) Nature , vol.446 , Issue.7137 , pp. 758-764
    • Mullighan, C.G.1    Goorha, S.2    Radtke, I.3
  • 13
    • 43049139905 scopus 로고    scopus 로고
    • Bcr-abl1 lymphoblastic leukaemia is characterized by the deletion of ikaros
    • Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 2008;453(7191): 110-114.
    • (2008) Nature , vol.453 , Issue.7191 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3
  • 14
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of ikzf1 and prognosis in acute lymphoblastic leukemia
    • Mullighan CG, Su X, Zhang J, et al; Children’s Oncology Group. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med. 2009;360(5):470-480.
    • (2009) N Engl J Med. , vol.360 , Issue.5 , pp. 470-480
    • Mullighan, C.G.1    Su, X.2    Zhang, J.3
  • 15
    • 59449091025 scopus 로고    scopus 로고
    • Acute lymphoblastic leukemia - On the wings of ikaros
    • Georgopoulos K. Acute lymphoblastic leukemia - on the wings of IKAROS. N Engl J Med. 2009;360(5):524-526.
    • (2009) N Engl J Med , vol.360 , Issue.5 , pp. 524-526
    • Georgopoulos, K.1
  • 16
    • 0037544006 scopus 로고    scopus 로고
    • A complex network of regulatory elements in ikaros and their activity during hemo-lymphopoiesis
    • Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 2003; 22(9):2211-2223.
    • (2003) EMBO J , vol.22 , Issue.9 , pp. 2211-2223
    • Kaufmann, C.1    Yoshida, T.2    Perotti, E.A.3    Landhuis, E.4    Wu, P.5    Georgopoulos, K.6
  • 17
    • 83855160775 scopus 로고    scopus 로고
    • Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis
    • Zhang J, Jackson AF, Naito T, et al. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nat Immunol. 2012; 13(1):86-94.
    • (2012) Nat Immunol , vol.13 , Issue.1 , pp. 86-94
    • Zhang, J.1    Jackson, A.F.2    Naito, T.3
  • 18
    • 84886909517 scopus 로고    scopus 로고
    • A far downstream enhancer for murine bcl11b controls its t-cell specific expression
    • Li L, Zhang JA, Dose M, et al. A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. Blood. 2013;122(6):902-911.
    • (2013) Blood , vol.122 , Issue.6 , pp. 902-911
    • Li, L.1    Zhang, J.A.2    Dose, M.3
  • 19
    • 84863012512 scopus 로고    scopus 로고
    • Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors
    • Yu M, Mazor T, Huang H, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012; 45(3):330-343.
    • (2012) Mol Cell , vol.45 , Issue.3 , pp. 330-343
    • Yu, M.1    Mazor, T.2    Huang, H.3
  • 20
    • 79955550445 scopus 로고    scopus 로고
    • A user’s guide to the encyclopedia of dna elements (encode)
    • Consortium EP; ENCODE Project Consortium. A user’s guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 2011;9(4):e1001046.
    • (2011) Plos Biol , vol.9 , Issue.4
  • 21
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short dna sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009;10(3):R25.
    • (2009) Genome Biol , vol.10 , Issue.3 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 22
    • 53849146020 scopus 로고    scopus 로고
    • Model-based analysis of chip-seq (macs)
    • Zhang Y, Liu T, Meyer CA, et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137.
    • (2008) Genome Biol , vol.9 , Issue.9 , pp. R137
    • Zhang, Y.1    Liu, T.2    Meyer, C.A.3
  • 23
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J, Kheradpour P, Mikkelsen TS, et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature. 2011; 473(7345):43-49.
    • (2011) Nature , vol.473 , Issue.7345 , pp. 43-49
    • Ernst, J.1    Kheradpour, P.2    Mikkelsen, T.S.3
  • 24
    • 77952367798 scopus 로고    scopus 로고
    • Widespread transcription at neuronal activity-regulated enhancers
    • Kim TK, Hemberg M, Gray JM, et al. Widespread transcription at neuronal activity-regulated enhancers. Nature. 2010;465(7295):182-187.
    • (2010) Nature , vol.465 , Issue.7295 , pp. 182-187
    • Kim, T.K.1    Hemberg, M.2    Gray, J.M.3
  • 25
    • 0033103013 scopus 로고    scopus 로고
    • Ikaros sets thresholds for t cell activation and regulates chromosome propagation
    • Avitahl N, Winandy S, Friedrich C, Jones B, Ge Y, Georgopoulos K. Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity. 1999;10(3):333-343.
    • (1999) Immunity , vol.10 , Issue.3 , pp. 333-343
    • Avitahl, N.1    Winandy, S.2    Friedrich, C.3    Jones, B.4    Ge, Y.5    Georgopoulos, K.6
  • 26
    • 0032745697 scopus 로고    scopus 로고
    • Pre-t cell receptor (tcr) and tcr-controlled checkpoints in t cell differentiation are set by ikaros
    • Winandy S, Wu L, Wang JH, Georgopoulos K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. J Exp Med. 1999;190(8):1039-1048.
    • (1999) J Exp Med , vol.190 , Issue.8 , pp. 1039-1048
    • Winandy, S.1    Wu, L.2    Wang, J.H.3    Georgopoulos, K.4
  • 27
    • 0026451087 scopus 로고
    • Ikaros, an early lymphoid-specific transcription factor and a putative mediator for t cell commitment
    • Georgopoulos K, Moore DD, Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science. 1992;258(5083):808-812.
    • (1992) Science , vol.258 , Issue.5083 , pp. 808-812
    • Georgopoulos, K.1    Moore, D.D.2    Derfler, B.3
  • 28
    • 34548220856 scopus 로고    scopus 로고
    • Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation
    • Agoston DV, Szemes M, Dobi A, et al. Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation. J Neurochem. 2007;102(6):1805-1816.
    • (2007) J Neurochem , vol.102 , Issue.6 , pp. 1805-1816
    • Agoston, D.V.1    Szemes, M.2    Dobi, A.3
  • 29
    • 77649251080 scopus 로고    scopus 로고
    • Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons
    • Martín-Ibáñez R, Crespo E, Urbán N, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. J Comp Neurol. 2010;518(3):329-351.
    • (2010) J Comp Neurol. , vol.518 , Issue.3 , pp. 329-351
    • Martín-Ibáñez, R.1    Crespo, E.2    Urbán, N.3
  • 30
    • 53049108478 scopus 로고    scopus 로고
    • Ikaros confers early temporal competence to mouse retinal progenitor cells
    • Elliott J, Jolicoeur C, Ramamurthy V, Cayouette M. Ikaros confers early temporal competence to mouse retinal progenitor cells. Neuron. 2008; 60(1):26-39.
    • (2008) Neuron , vol.60 , Issue.1 , pp. 26-39
    • Elliott, J.1    Jolicoeur, C.2    Ramamurthy, V.3    Cayouette, M.4
  • 31
    • 84055178955 scopus 로고    scopus 로고
    • T-cell factor 1 is a gatekeeper for t-cell specification in response to notch signaling
    • Germar K, Dose M, Konstantinou T, et al. T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling. Proc Natl Acad Sci USA. 2011;108(50):20060-20065.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.50 , pp. 20060-20065
    • Germar, K.1    Dose, M.2    Konstantinou, T.3
  • 32
    • 77952908743 scopus 로고    scopus 로고
    • A large fraction of extragenic rna pol ii transcription sites overlap enhancers
    • De Santa F, Barozzi I, Mietton F, et al. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol. 2010;8(5): e1000384.
    • (2010) Plos Biol , vol.8 , Issue.5
    • De Santa, F.1    Barozzi, I.2    Mietton, F.3
  • 33
    • 80054910846 scopus 로고    scopus 로고
    • H3k4 tri-methylation provides an epigenetic signature of active enhancers
    • Pekowska A, Benoukraf T, Zacarias-Cabeza J, et al. H3K4 tri-methylation provides an epigenetic signature of active enhancers. EMBO J. 2011; 30(20):4198-4210.
    • (2011) EMBO J , vol.30 , Issue.20 , pp. 4198-4210
    • Pekowska, A.1    Benoukraf, T.2    Zacarias-Cabeza, J.3
  • 34
    • 79961022267 scopus 로고    scopus 로고
    • Transcription initiation platforms and gtf recruitment at tissue-specific enhancers and promoters
    • Koch F, Fenouil R, Gut M, et al. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat Struct Mol Biol. 2011;18(8):956-963.
    • (2011) Nat Struct Mol Biol , vol.18 , Issue.8 , pp. 956-963
    • Koch, F.1    Fenouil, R.2    Gut, M.3
  • 35
    • 14244255401 scopus 로고    scopus 로고
    • The lambda5-vpreb1 locus - A model system for studying gene regulation during early b cell development
    • Sabbattini P, Dillon N. The lambda5-VpreB1 locus - a model system for studying gene regulation during early B cell development. Semin Immunol. 2005;17(2):121-127.
    • (2005) Semin Immunol , vol.17 , Issue.2 , pp. 121-127
    • Sabbattini, P.1    Dillon, N.2
  • 36
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early t-cell precursor acute lymphoblastic leukaemia
    • Zhang J, Ding L, Holmfeldt L, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012;481(7380):157-163.
    • (2012) Nature , vol.481 , Issue.7380 , pp. 157-163
    • Zhang, J.1    Ding, L.2    Holmfeldt, L.3
  • 37
    • 84864368299 scopus 로고    scopus 로고
    • Ikaros deletions dictate a unique gene expression signature in patients with adult b-cell acute lymphoblastic leukemia
    • Iacobucci I, Iraci N, Messina M, et al. IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. PLoS ONE. 2012;7(7): e40934.
    • (2012) Plos ONE , vol.7 , Issue.7
    • Iacobucci, I.1    Iraci, N.2    Messina, M.3
  • 38
    • 84873571191 scopus 로고    scopus 로고
    • Biclonal and biallelic deletions occur in 20% of b-all cases with ikzf1 mutations
    • Dupuis A, Gaub MP, Legrain M, et al. Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations. Leukemia. 2013;27(2): 503-507.
    • (2013) Leukemia , vol.27 , Issue.2 , pp. 503-507
    • Dupuis, A.1    Gaub, M.P.2    Legrain, M.3
  • 39
    • 84888075072 scopus 로고    scopus 로고
    • Function of ikaros as a tumor suppressor in b cell acute lymphoblastic leukemia
    • Kastner P, Dupuis A, Gaub MP, Herbrecht R, Lutz P, Chan S. Function of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemia. Am J Blood Res. 2013;3(1):1-13.
    • (2013) Am J Blood Res , vol.3 , Issue.1 , pp. 1-13
    • Kastner, P.1    Dupuis, A.2    Gaub, M.P.3    Herbrecht, R.4    Lutz, P.5    Chan, S.6


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