-
1
-
-
0027118569
-
Pancreatic carcinoma
-
[PMID: 1732772 DOI: 10.1056/nejm199202133260706]
-
Warshaw AL, Fernández-del Castillo C. Pancreatic carcinoma. N Engl J Med 1992; 326: 455-465 [PMID: 1732772 DOI: 10.1056/nejm199202133260706]
-
(1992)
N Engl J Med
, vol.326
, pp. 455-465
-
-
Warshaw, A.L.1
Fernández-del Castillo, C.2
-
2
-
-
1642588228
-
Pancreatic cancer
-
[PMID: 15051286 DOI: 10.1016/ S0140-6736(04)15841-8]
-
Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet 2004; 363: 1049-1057 [PMID: 15051286 DOI: 10.1016/ S0140-6736(04)15841-8]
-
(2004)
Lancet
, vol.363
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
3
-
-
84872967522
-
Cancer statistics, 2013
-
[PMID: 23335087 DOI: 10.3322/caac.21166]
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013; 63: 11-30 [PMID: 23335087 DOI: 10.3322/caac.21166]
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
4
-
-
62249117097
-
Familial pancreatic cancer
-
[PMID: 19260742 DOI: 10.1043/1543-2165-133.3.365]
-
Shi C, Hruban RH, Klein AP. Familial pancreatic cancer. Arch Pathol Lab Med 2009; 133: 365-374 [PMID: 19260742 DOI: 10.1043/1543-2165-133.3.365]
-
(2009)
Arch Pathol Lab Med
, vol.133
, pp. 365-374
-
-
Shi, C.1
Hruban, R.H.2
Klein, A.P.3
-
5
-
-
84866514182
-
The burning question: Why is smoking a risk factor for pancreatic cancer?
-
[PMID: 22898636 DOI: 10.1016/j.pan.2012.06.002]
-
Pandol SJ, Apte MV, Wilson JS, Gukovskaya AS, Edderkaoui M. The burning question: why is smoking a risk factor for pancreatic cancer? Pancreatology 2012; 12: 344-349 [PMID: 22898636 DOI: 10.1016/j.pan.2012.06.002]
-
(2012)
Pancreatology
, vol.12
, pp. 344-349
-
-
Pandol, S.J.1
Apte, M.V.2
Wilson, J.S.3
Gukovskaya, A.S.4
Edderkaoui, M.5
-
6
-
-
84872274536
-
Diabetes mellitus and cancer risk: Review of the epidemiological evidence
-
[PMID: 23066889 DOI: 10.1111/cas.12043]
-
Shikata K, Ninomiya T, Kiyohara Y. Diabetes mellitus and cancer risk: review of the epidemiological evidence. Cancer Sci 2013; 104: 9-14 [PMID: 23066889 DOI: 10.1111/cas.12043]
-
(2013)
Cancer Sci
, vol.104
, pp. 9-14
-
-
Shikata, K.1
Ninomiya, T.2
Kiyohara, Y.3
-
7
-
-
84876796439
-
Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer
-
[PMID: 23622129 DOI: 10.1053/j.gastro.2013.02.007]
-
Gukovsky I, Li N, Todoric J, Gukovskaya A, Karin M. Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology 2013; 144: 1199-1209. e4 [PMID: 23622129 DOI: 10.1053/j.gastro.2013.02.007]
-
(2013)
Gastroenterology
, vol.144
-
-
Gukovsky, I.1
Li, N.2
Todoric, J.3
Gukovskaya, A.4
Karin, M.5
-
8
-
-
69949185673
-
Update on pancreatic intraepithelial neoplasia
-
[PMID: 18787611]
-
Hruban RH, Maitra A, Goggins M. Update on pancreatic intraepithelial neoplasia. Int J Clin Exp Pathol 2008; 1: 306-316 [PMID: 18787611]
-
(2008)
Int J Clin Exp Pathol
, vol.1
, pp. 306-316
-
-
Hruban, R.H.1
Maitra, A.2
Goggins, M.3
-
9
-
-
34249898611
-
Molecular genetics of pancreatic intraepithelial neoplasia
-
[PMID: 17520196 DOI: 10.1007/s00534-006-1166-5]
-
Feldmann G, Beaty R, Hruban RH, Maitra A. Molecular genetics of pancreatic intraepithelial neoplasia. J Hepatobiliary Pancreat Surg 2007; 14: 224-232 [PMID: 17520196 DOI: 10.1007/s00534-006-1166-5]
-
(2007)
J Hepatobiliary Pancreat Surg
, vol.14
, pp. 224-232
-
-
Feldmann, G.1
Beaty, R.2
Hruban, R.H.3
Maitra, A.4
-
10
-
-
84876786403
-
A starring role for stellate cells in the pancreatic cancer microenvironment
-
[PMID: 23622130 DOI: 10.1053/j.gastro.2012.11.037]
-
Apte MV, Wilson JS, Lugea A, Pandol SJ. A starring role for stellate cells in the pancreatic cancer microenvironment. Gastroenterology 2013; 144: 1210-1219 [PMID: 23622130 DOI: 10.1053/j.gastro.2012.11.037]
-
(2013)
Gastroenterology
, vol.144
, pp. 1210-1219
-
-
Apte, M.V.1
Wilson, J.S.2
Lugea, A.3
Pandol, S.J.4
-
11
-
-
70449719361
-
Identification of human pancreatic cancer stem cells
-
[PMID: 19582426 DOI: 10.1007/978-1-59745-280-9_10]
-
Li C, Lee CJ, Simeone DM. Identification of human pancreatic cancer stem cells. Methods Mol Biol 2009; 568: 161-173 [PMID: 19582426 DOI: 10.1007/978-1-59745-280-9_10]
-
(2009)
Methods Mol Biol
, vol.568
, pp. 161-173
-
-
Li, C.1
Lee, C.J.2
Simeone, D.M.3
-
12
-
-
84868212819
-
Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head
-
[PMID: 22931216 DOI: 10.1111/j.1349-7006.2012.02411.x]
-
Yoshikawa K, Mitsunaga S, Kinoshita T, Konishi M, Takahashi S, Gotohda N, Kato Y, Aizawa M, Ochiai A. Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head. Cancer Sci 2012; 103: 2012-2020 [PMID: 22931216 DOI: 10.1111/j.1349-7006.2012.02411.x]
-
(2012)
Cancer Sci
, vol.103
, pp. 2012-2020
-
-
Yoshikawa, K.1
Mitsunaga, S.2
Kinoshita, T.3
Konishi, M.4
Takahashi, S.5
Gotohda, N.6
Kato, Y.7
Aizawa, M.8
Ochiai, A.9
-
13
-
-
77951755278
-
Pancreatic cancer
-
[PMID: 20427809 DOI: 10.1056/NEJMra0901557]
-
Hidalgo M. Pancreatic cancer. N Engl J Med 2010; 362: 1605-1617 [PMID: 20427809 DOI: 10.1056/NEJMra0901557]
-
(2010)
N Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
14
-
-
84866755869
-
New insights into pancreatic cancer biology
-
[PMID: 22987949 DOI: 10.1093/annonc/mds313]
-
Hidalgo M. New insights into pancreatic cancer biology. Ann Oncol 2012; 23 Suppl 10: x135-x138 [PMID: 22987949 DOI: 10.1093/annonc/mds313]
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 10
-
-
Hidalgo, M.1
-
15
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
[PMID: 9196156]
-
Burris HA, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997; 15: 2403-2413 [PMID: 9196156]
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
16
-
-
70350635407
-
Gemcitabine chemoresistance in pancreatic cancer: Molecular mechanisms and potential solutions
-
[PMID: 19214867 DOI: 10.1080/00365520902745039]
-
Andersson R, Aho U, Nilsson BI, Peters GJ, Pastor-Anglada M, Rasch W, Sandvold ML. Gemcitabine chemoresistance in pancreatic cancer: molecular mechanisms and potential solutions. Scand J Gastroenterol 2009; 44: 782-786 [PMID: 19214867 DOI: 10.1080/00365520902745039]
-
(2009)
Scand J Gastroenterol
, vol.44
, pp. 782-786
-
-
Andersson, R.1
Aho, U.2
Nilsson, B.I.3
Peters, G.J.4
Pastor-Anglada, M.5
Rasch, W.6
Sandvold, M.L.7
-
17
-
-
84880315622
-
Pancreatic cancer-cost for overtreatment with gemcitabine
-
[PMID: 23244671 DOI: 10.3109/0284186X.2012.744 140]
-
Ansari D, Tingstedt B, Andersson R. Pancreatic cancer-cost for overtreatment with gemcitabine. Acta Oncol 2013; 52: 1146-1151 [PMID: 23244671 DOI: 10.3109/0284186X.2012.744 140]
-
(2013)
Acta Oncol
, vol.52
, pp. 1146-1151
-
-
Ansari, D.1
Tingstedt, B.2
Andersson, R.3
-
18
-
-
84880057880
-
First line therapy for metastatic pancreatic cancer
-
[PMID: 23846923 DOI: 10.6092/1590-8577/1667]
-
Jarboe J, Saif MW. First line therapy for metastatic pancreatic cancer. JOP 2013; 14: 340-343 [PMID: 23846923 DOI: 10.6092/1590-8577/1667]
-
(2013)
JOP
, vol.14
, pp. 340-343
-
-
Jarboe, J.1
Saif, M.W.2
-
19
-
-
84885762423
-
Links between Toll-like receptor 4 and breast cancer
-
[PMID: 23526132 DOI: 10.4161/onci.22945]
-
Ahmed A, Redmond HP, Wang JH. Links between Toll-like receptor 4 and breast cancer. Oncoimmunology 2013; 2: e22945 [PMID: 23526132 DOI: 10.4161/onci.22945]
-
(2013)
Oncoimmunology
, vol.2
-
-
Ahmed, A.1
Redmond, H.P.2
Wang, J.H.3
-
20
-
-
81855176234
-
Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer
-
[PMID: 21920464 DOI: 10.1053/j.gastro.2011.08.043]
-
Eyking A, Ey B, Rünzi M, Roig AI, Reis H, Schmid KW, Gerken G, Podolsky DK, Cario E. Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer. Gastroenterology 2011; 141: 2154-2165 [PMID: 21920464 DOI: 10.1053/j.gastro.2011.08.043]
-
(2011)
Gastroenterology
, vol.141
, pp. 2154-2165
-
-
Eyking, A.1
Ey, B.2
Rünzi, M.3
Roig, A.I.4
Reis, H.5
Schmid, K.W.6
Gerken, G.7
Podolsky, D.K.8
Cario, E.9
-
21
-
-
84863113633
-
Immunotherapies for non-small-cell lung cancer and mesothelioma
-
[PMID: 22748269 DOI: 10.1016/S1470-2045(12)70126-2]
-
Thomas A, Hassan R. Immunotherapies for non-small-cell lung cancer and mesothelioma. Lancet Oncol 2012; 13: e301-e310 [PMID: 22748269 DOI: 10.1016/S1470-2045(12)70126-2]
-
(2012)
Lancet Oncol
, vol.13
-
-
Thomas, A.1
Hassan, R.2
-
22
-
-
77954214387
-
Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray
-
[PMID: 20510208 DOI: 10.1016/j.bcp.2010.05.018]
-
Morse DL, Balagurunathan Y, Hostetter G, Trissal M, Tafreshi NK, Burke N, Lloyd M, Enkemann S, Coppola D, Hruby VJ, Gillies RJ, Han H. Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray. Biochem Pharmacol 2010; 80: 748-754 [PMID: 20510208 DOI: 10.1016/j.bcp.2010.05.018]
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 748-754
-
-
Morse, D.L.1
Balagurunathan, Y.2
Hostetter, G.3
Trissal, M.4
Tafreshi, N.K.5
Burke, N.6
Lloyd, M.7
Enkemann, S.8
Coppola, D.9
Hruby, V.J.10
Gillies, R.J.11
Han, H.12
-
23
-
-
84901210724
-
Pancreatic cancer screening by TLR phenotyping
-
Abstract nr 894. [DOI: 10.1158/1538-7445.AM2011-894]
-
Rosenberg JS, Singh S, Raul S, Tong Z, Guha S. Pancreatic cancer screening by TLR phenotyping. Cancer Research 2011; 71: Abstract nr 894 [DOI: 10.1158/1538-7445.AM2011-894]
-
(2011)
Cancer Research
, vol.71
-
-
Rosenberg, J.S.1
Singh, S.2
Raul, S.3
Tong, Z.4
Guha, S.5
-
24
-
-
77955383770
-
DAMPening inflammation by modulating TLR signalling
-
2010: [PMID: 20706656 DOI: 10.1155/2010/672395]
-
Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010; 2010: [PMID: 20706656 DOI: 10.1155/2010/672395]
-
(2010)
Mediators Inflamm
-
-
Piccinini, A.M.1
Midwood, K.S.2
-
25
-
-
80051814602
-
Targeting of Toll-like receptors: A decade of progress in combating infectious diseases
-
[PMID: 21719349 DOI: 10.1016/S1473-3099(11)70099-8]
-
Hedayat M, Netea MG, Rezaei N. Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. Lancet Infect Dis 2011; 11: 702-712 [PMID: 21719349 DOI: 10.1016/S1473-3099(11)70099-8]
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 702-712
-
-
Hedayat, M.1
Netea, M.G.2
Rezaei, N.3
-
26
-
-
34247566510
-
The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling
-
[PMID: 17457343 DOI: 10.1038/ nri2079]
-
O'Neill LA, Bowie AG. The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling. Nat Rev Immunol 2007; 7: 353-364 [PMID: 17457343 DOI: 10.1038/ nri2079]
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
27
-
-
67649422321
-
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
-
[PMID: 19474110 DOI: 10.1124/pr.109.001073]
-
O'Neill LA, Bryant CE, Doyle SL. Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol Rev 2009; 61: 177-197 [PMID: 19474110 DOI: 10.1124/pr.109.001073]
-
(2009)
Pharmacol Rev
, vol.61
, pp. 177-197
-
-
O'Neill, L.A.1
Bryant, C.E.2
Doyle, S.L.3
-
28
-
-
1642275654
-
Signaling danger: Tolllike receptors and their potential roles in kidney disease
-
[PMID: 15034087 DOI: 10.1097/01.ASN.0000121781.89599.16]
-
Anders HJ, Banas B, Schlöndorff D. Signaling danger: tolllike receptors and their potential roles in kidney disease. J Am Soc Nephrol 2004; 15: 854-867 [PMID: 15034087 DOI: 10.1097/01.ASN.0000121781.89599.16]
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 854-867
-
-
Anders, H.J.1
Banas, B.2
Schlöndorff, D.3
-
29
-
-
1542721504
-
Toll-like receptor 2 as a major gene for asthma in children of European farmers
-
[PMID: 15007351 DOI: 10.1016/j.jaci.2003.12.374]
-
Eder W, Klimecki W, Yu L, von Mutius E, Riedler J, Braun-Fahrländer C, Nowak D, Martinez FD. Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol 2004; 113: 482-488 [PMID: 15007351 DOI: 10.1016/j.jaci.2003.12.374]
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 482-488
-
-
Eder, W.1
Klimecki, W.2
Yu, L.3
von Mutius, E.4
Riedler, J.5
Braun-Fahrländer, C.6
Nowak, D.7
Martinez, F.D.8
-
30
-
-
52049124515
-
Role of Toll like receptor signaling pathway in ischemic coronary artery disease
-
[PMID: 18508689 DOI: 10.2741/3397]
-
Satoh M, Ishikawa Y, Minami Y, Takahashi Y, Nakamura M. Role of Toll like receptor signaling pathway in ischemic coronary artery disease. Front Biosci 2008; 13: 6708-6715 [PMID: 18508689 DOI: 10.2741/3397]
-
(2008)
Front Biosci
, vol.13
, pp. 6708-6715
-
-
Satoh, M.1
Ishikawa, Y.2
Minami, Y.3
Takahashi, Y.4
Nakamura, M.5
-
31
-
-
0036918723
-
Differential recognition of structural details of bacterial lipopeptides by toll-like receptors
-
[PMID: 12432564]
-
Morr M, Takeuchi O, Akira S, Simon MM, Mühlradt PF. Differential recognition of structural details of bacterial lipopeptides by toll-like receptors. Eur J Immunol 2002; 32: 3337-3347 [PMID: 12432564]
-
(2002)
Eur J Immunol
, vol.32
, pp. 3337-3347
-
-
Morr, M.1
Takeuchi, O.2
Akira, S.3
Simon, M.M.4
Mühlradt, P.F.5
-
32
-
-
0034650420
-
Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2-and MyD88-dependent signaling pathway
-
[PMID: 10623793]
-
Takeuchi O, Kaufmann A, Grote K, Kawai T, Hoshino K, Morr M, Mühlradt PF, Akira S. Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2-and MyD88-dependent signaling pathway. J Immunol 2000; 164: 554-557 [PMID: 10623793]
-
(2000)
J Immunol
, vol.164
, pp. 554-557
-
-
Takeuchi, O.1
Kaufmann, A.2
Grote, K.3
Kawai, T.4
Hoshino, K.5
Morr, M.6
Mühlradt, P.F.7
Akira, S.8
-
33
-
-
10744221163
-
Tumour suppression induced by the macrophage activating lipopeptide MALP-2 in an ultrasound guided pancreatic carcinoma mouse model
-
[PMID: 14960515 DOI: 10.1136/ gut.2003.026005]
-
Schneider C, Schmidt T, Ziske C, Tiemann K, Lee KM, Uhlinsky V, Behrens P, Sauerbruch T, Schmidt-Wolf IG, Mühlradt PF, Schmidt J, Märten A. Tumour suppression induced by the macrophage activating lipopeptide MALP-2 in an ultrasound guided pancreatic carcinoma mouse model. Gut 2004; 53: 355-361 [PMID: 14960515 DOI: 10.1136/ gut.2003.026005]
-
(2004)
Gut
, vol.53
, pp. 355-361
-
-
Schneider, C.1
Schmidt, T.2
Ziske, C.3
Tiemann, K.4
Lee, K.M.5
Uhlinsky, V.6
Behrens, P.7
Sauerbruch, T.8
Schmidt-Wolf, I.G.9
Mühlradt, P.F.10
Schmidt, J.11
Märten, A.12
-
34
-
-
0038189845
-
Synthetic mycoplasma-derived lipopeptide MALP-2 induces maturation and function of dendritic cells
-
[PMID: 12777064 DOI: 10.1078/0171-2985-00234]
-
Weigt H, Mühlradt PF, Emmendörffer A, Krug N, Braun A. Synthetic mycoplasma-derived lipopeptide MALP-2 induces maturation and function of dendritic cells. Immunobiology 2003; 207: 223-233 [PMID: 12777064 DOI: 10.1078/0171-2985-00234]
-
(2003)
Immunobiology
, vol.207
, pp. 223-233
-
-
Weigt, H.1
Mühlradt, P.F.2
Emmendörffer, A.3
Krug, N.4
Braun, A.5
-
35
-
-
34548316162
-
Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: A phase I/II trial
-
[PMID: 17667928 DOI: 10.1038/ sj.bjc.6603903]
-
Schmidt J, Welsch T, Jäger D, Mühlradt PF, Büchler MW, Märten A. Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: a phase I/II trial. Br J Cancer 2007; 97: 598-604 [PMID: 17667928 DOI: 10.1038/ sj.bjc.6603903]
-
(2007)
Br J Cancer
, vol.97
, pp. 598-604
-
-
Schmidt, J.1
Welsch, T.2
Jäger, D.3
Mühlradt, P.F.4
Büchler, M.W.5
Märten, A.6
-
36
-
-
84863284114
-
Polysaccharide-K (PSK) in cancer--old story, new possibilities?
-
[PMID: 22204346 DOI: 10.2174/092986712798992020]
-
Sun C, Rosendahl AH, Wang XD, Wu DQ, Andersson R. Polysaccharide-K (PSK) in cancer--old story, new possibilities? Curr Med Chem 2012; 19: 757-762 [PMID: 22204346 DOI: 10.2174/092986712798992020]
-
(2012)
Curr Med Chem
, vol.19
, pp. 757-762
-
-
Sun, C.1
Rosendahl, A.H.2
Wang, X.D.3
Wu, D.Q.4
Andersson, R.5
-
37
-
-
0030796940
-
Effect of Krestin as adjuvant treatment following radical radiotherapy in nonsmall cell lung cancer patients
-
[PMID: 9043766]
-
Hayakawa K, Mitsuhashi N, Saito Y, Nakayama Y, Furuta M, Nakamoto S, Kawashima M, Niibe H. Effect of Krestin as adjuvant treatment following radical radiotherapy in nonsmall cell lung cancer patients. Cancer Detect Prev 1997; 21: 71-77 [PMID: 9043766]
-
(1997)
Cancer Detect Prev
, vol.21
, pp. 71-77
-
-
Hayakawa, K.1
Mitsuhashi, N.2
Saito, Y.3
Nakayama, Y.4
Furuta, M.5
Nakamoto, S.6
Kawashima, M.7
Niibe, H.8
-
38
-
-
78751474671
-
Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells
-
[PMID: 21068144 DOI: 10.1158/1078-0432.CCR-10-1763]
-
Lu H, Yang Y, Gad E, Wenner CA, Chang A, Larson ER, Dang Y, Martzen M, Standish LJ, Disis ML. Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells. Clin Cancer Res 2011; 17: 67-76 [PMID: 21068144 DOI: 10.1158/1078-0432.CCR-10-1763]
-
(2011)
Clin Cancer Res
, vol.17
, pp. 67-76
-
-
Lu, H.1
Yang, Y.2
Gad, E.3
Wenner, C.A.4
Chang, A.5
Larson, E.R.6
Dang, Y.7
Martzen, M.8
Standish, L.J.9
Disis, M.L.10
-
39
-
-
11144356502
-
Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: A randomised controlled study
-
[PMID: 14997197 DOI: 10.1038/sj.bjc.6601619]
-
Ohwada S, Ikeya T, Yokomori T, Kusaba T, Roppongi T, Takahashi T, Nakamura S, Kakinuma S, Iwazaki S, Ishikawa H, Kawate S, Nakajima T, Morishita Y. Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. Br J Cancer 2004; 90: 1003-1010 [PMID: 14997197 DOI: 10.1038/sj.bjc.6601619]
-
(2004)
Br J Cancer
, vol.90
, pp. 1003-1010
-
-
Ohwada, S.1
Ikeya, T.2
Yokomori, T.3
Kusaba, T.4
Roppongi, T.5
Takahashi, T.6
Nakamura, S.7
Kakinuma, S.8
Iwazaki, S.9
Ishikawa, H.10
Kawate, S.11
Nakajima, T.12
Morishita, Y.13
-
40
-
-
84873085234
-
Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells
-
[PMID: 23217280 DOI: 10.1016/j.pan.2012.09.004]
-
Rosendahl AH, Sun C, Wu D, Andersson R. Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells. Pancreatology 2012; 12: 467-474 [PMID: 23217280 DOI: 10.1016/j.pan.2012.09.004]
-
(2012)
Pancreatology
, vol.12
, pp. 467-474
-
-
Rosendahl, A.H.1
Sun, C.2
Wu, D.3
Andersson, R.4
-
41
-
-
84869989377
-
Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy
-
[PMID: 23098072 DOI: 10.1021/ jm301002f]
-
Huynh AS, Chung WJ, Cho HI, Moberg VE, Celis E, Morse DL, Vagner J. Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy. J Med Chem 2012; 55: 9751-9762 [PMID: 23098072 DOI: 10.1021/ jm301002f]
-
(2012)
J Med Chem
, vol.55
, pp. 9751-9762
-
-
Huynh, A.S.1
Chung, W.J.2
Cho, H.I.3
Moberg, V.E.4
Celis, E.5
Morse, D.L.6
Vagner, J.7
-
42
-
-
84901196792
-
Intraoperative detection of pancreatic cancer using tumor targeted fluorescent probes
-
Huynh AS, Patek R, Abrahams D, Baldwin MK, Lioyd MC, Centeno BA, Vagner J, Gillies R, Morse DL. Intraoperative detection of pancreatic cancer using tumor targeted fluorescent probes. Mol Imaging Biol 2012; 14: S979
-
(2012)
Mol Imaging Biol
, vol.14
-
-
Huynh, A.S.1
Patek, R.2
Abrahams, D.3
Baldwin, M.K.4
Lioyd, M.C.5
Centeno, B.A.6
Vagner, J.7
Gillies, R.8
Morse, D.L.9
-
43
-
-
65449128170
-
Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma
-
[PMID: 19302292 DOI: 10.1111/j.1349-7006.2009.01106.x]
-
Kim SA, Lee Y, Jung DE, Park KH, Park JY, Gang J, Jeon SB, Park EC, Kim YG, Lee B, Liu Q, Zeng W, Yeramilli S, Lee S, Koh SS, Song SY. Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma. Cancer Sci 2009; 100: 828-836 [PMID: 19302292 DOI: 10.1111/j.1349-7006.2009.01106.x]
-
(2009)
Cancer Sci
, vol.100
, pp. 828-836
-
-
Kim, S.A.1
Lee, Y.2
Jung, D.E.3
Park, K.H.4
Park, J.Y.5
Gang, J.6
Jeon, S.B.7
Park, E.C.8
Kim, Y.G.9
Lee, B.10
Liu, Q.11
Zeng, W.12
Yeramilli, S.13
Lee, S.14
Koh, S.S.15
Song, S.Y.16
-
44
-
-
73849145679
-
PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression
-
[PMID: 19784070 DOI: 10.1038/onc.2009.298]
-
Lee Y, Kim SJ, Park HD, Park EH, Huang SM, Jeon SB, Kim JM, Lim DS, Koh SS. PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression. Oncogene 2010; 29: 56-67 [PMID: 19784070 DOI: 10.1038/onc.2009.298]
-
(2010)
Oncogene
, vol.29
, pp. 56-67
-
-
Lee, Y.1
Kim, S.J.2
Park, H.D.3
Park, E.H.4
Huang, S.M.5
Jeon, S.B.6
Kim, J.M.7
Lim, D.S.8
Koh, S.S.9
-
45
-
-
78651407343
-
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
-
[PMID: 20802527 DOI: 10.1038/onc.2010.401]
-
Park HD, Lee Y, Oh YK, Jung JG, Park YW, Myung K, Kim KH, Koh SS, Lim DS. Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation. Oncogene 2011; 30: 201-211 [PMID: 20802527 DOI: 10.1038/onc.2010.401]
-
(2011)
Oncogene
, vol.30
, pp. 201-211
-
-
Park, H.D.1
Lee, Y.2
Oh, Y.K.3
Jung, J.G.4
Park, Y.W.5
Myung, K.6
Kim, K.H.7
Koh, S.S.8
Lim, D.S.9
-
46
-
-
4344668629
-
Breast cancer with synchronous metastases: Trends in survival during a 14-year period
-
[PMID: 15310773 DOI: 10.1200/ JCO.2004.08.095]
-
Andre F, Slimane K, Bachelot T, Dunant A, Namer M, Barrelier A, Kabbaj O, Spano JP, Marsiglia H, Rouzier R, Delaloge S, Spielmann M. Breast cancer with synchronous metastases: trends in survival during a 14-year period. J Clin Oncol 2004; 22: 3302-3308 [PMID: 15310773 DOI: 10.1200/ JCO.2004.08.095]
-
(2004)
J Clin Oncol
, vol.22
, pp. 3302-3308
-
-
Andre, F.1
Slimane, K.2
Bachelot, T.3
Dunant, A.4
Namer, M.5
Barrelier, A.6
Kabbaj, O.7
Spano, J.P.8
Marsiglia, H.9
Rouzier, R.10
Delaloge, S.11
Spielmann, M.12
-
47
-
-
66149113298
-
Toll-like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity
-
[PMID: 19282652 DOI: 10.1620/ tjem.217.175]
-
Soga Y, Komori H, Miyazaki T, Arita N, Terada M, Kamada K, Tanaka Y, Fujino T, Hiasa Y, Matsuura B, Onji M, Nose M. Toll-like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity. Tohoku J Exp Med 2009; 217: 175-184 [PMID: 19282652 DOI: 10.1620/ tjem.217.175]
-
(2009)
Tohoku J Exp Med
, vol.217
, pp. 175-184
-
-
Soga, Y.1
Komori, H.2
Miyazaki, T.3
Arita, N.4
Terada, M.5
Kamada, K.6
Tanaka, Y.7
Fujino, T.8
Hiasa, Y.9
Matsuura, B.10
Onji, M.11
Nose, M.12
-
48
-
-
72249091840
-
Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells
-
[PMID: 19887600 DOI: 10.1158/0008-5472.CAN-09-1602]
-
Shojaei H, Oberg HH, Juricke M, Marischen L, Kunz M, Mundhenke C, Gieseler F, Kabelitz D, Wesch D. Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells. Cancer Res 2009; 69: 8710-8717 [PMID: 19887600 DOI: 10.1158/0008-5472.CAN-09-1602]
-
(2009)
Cancer Res
, vol.69
, pp. 8710-8717
-
-
Shojaei, H.1
Oberg, H.H.2
Juricke, M.3
Marischen, L.4
Kunz, M.5
Mundhenke, C.6
Gieseler, F.7
Kabelitz, D.8
Wesch, D.9
-
49
-
-
84866372497
-
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
-
[PMID: 22908323 DOI: 10.1084/ jem.20111706]
-
Ochi A, Nguyen AH, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, Zambirinis CP, Fallon NC, Rehman A, Pylayeva-Gupta Y, Badar S, Hajdu CH, Frey AB, Bar-Sagi D, Miller G. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med 2012; 209: 1671-1687 [PMID: 22908323 DOI: 10.1084/ jem.20111706]
-
(2012)
J Exp Med
, vol.209
, pp. 1671-1687
-
-
Ochi, A.1
Nguyen, A.H.2
Bedrosian, A.S.3
Mushlin, H.M.4
Zarbakhsh, S.5
Barilla, R.6
Zambirinis, C.P.7
Fallon, N.C.8
Rehman, A.9
Pylayeva-Gupta, Y.10
Badar, S.11
Hajdu, C.H.12
Frey, A.B.13
Bar-Sagi, D.14
Miller, G.15
-
50
-
-
67449156114
-
Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration
-
[PMID: 19470740 DOI: 10.1158/1078-0432. CCR-09-0005]
-
Schwartz AL, Malgor R, Dickerson E, Weeraratna AT, Slominski A, Wortsman J, Harii N, Kohn AD, Moon RT, Schwartz FL, Goetz DJ, Kohn LD, McCall KD. Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration. Clin Cancer Res 2009; 15: 4114-4122 [PMID: 19470740 DOI: 10.1158/1078-0432. CCR-09-0005]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4114-4122
-
-
Schwartz, A.L.1
Malgor, R.2
Dickerson, E.3
Weeraratna, A.T.4
Slominski, A.5
Wortsman, J.6
Harii, N.7
Kohn, A.D.8
Moon, R.T.9
Schwartz, F.L.10
Goetz, D.J.11
Kohn, L.D.12
McCall, K.D.13
-
51
-
-
67649515610
-
Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades
-
[PMID: 19424602 DOI: 10.3892/ijmm_00000190]
-
Katoh M, Katoh M. Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. Int J Mol Med 2009; 23: 763-769 [PMID: 19424602 DOI: 10.3892/ijmm_00000190]
-
(2009)
Int J Mol Med
, vol.23
, pp. 763-769
-
-
Katoh, M.1
Katoh, M.2
-
52
-
-
17844410902
-
Thyrocytes express a functional toll-like receptor 3: Overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis
-
[PMID: 15661832 DOI: 10.1210/me.2004-0100]
-
Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ, Kohn LD. Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis. Mol Endocrinol 2005; 19: 1231-1250 [PMID: 15661832 DOI: 10.1210/me.2004-0100]
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1231-1250
-
-
Harii, N.1
Lewis, C.J.2
Vasko, V.3
McCall, K.4
Benavides-Peralta, U.5
Sun, X.6
Ringel, M.D.7
Saji, M.8
Giuliani, C.9
Napolitano, G.10
Goetz, D.J.11
Kohn, L.D.12
-
53
-
-
70349484212
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
-
[PMID: 19808018 DOI: 10.1016/ j.cmet.2009.08.013]
-
Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC. MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab 2009; 10: 249-259 [PMID: 19808018 DOI: 10.1016/ j.cmet.2009.08.013]
-
(2009)
Cell Metab
, vol.10
, pp. 249-259
-
-
Kleinridders, A.1
Schenten, D.2
Könner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
Wunderlich, F.T.7
Medzhitov, R.8
Brüning, J.C.9
-
54
-
-
84873684086
-
Controversial role of toll-like receptors in acute pancreatitis
-
[PMID: 23431068 DOI: 10.3748/wjg.v19. i5.616]
-
Vaz J, Akbarshahi H, Andersson R. Controversial role of toll-like receptors in acute pancreatitis. World J Gastroenterol 2013; 19: 616-630 [PMID: 23431068 DOI: 10.3748/wjg.v19. i5.616]
-
(2013)
World J Gastroenterol
, vol.19
, pp. 616-630
-
-
Vaz, J.1
Akbarshahi, H.2
Andersson, R.3
-
55
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
[PMID: 17615359 DOI: 10.1126/science.1140488]
-
Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 2007; 317: 124-127 [PMID: 17615359 DOI: 10.1126/science.1140488]
-
(2007)
Science
, vol.317
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
56
-
-
79952724783
-
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
-
[PMID: 21339327 DOI: 10.1084/jem.20101876]
-
De Monte L, Reni M, Tassi E, Clavenna D, Papa I, Recalde H, Braga M, Di Carlo V, Doglioni C, Protti MP. Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J Exp Med 2011; 208: 469-478 [PMID: 21339327 DOI: 10.1084/jem.20101876]
-
(2011)
J Exp Med
, vol.208
, pp. 469-478
-
-
De Monte, L.1
Reni, M.2
Tassi, E.3
Clavenna, D.4
Papa, I.5
Recalde, H.6
Braga, M.7
Di Carlo, V.8
Doglioni, C.9
Protti, M.P.10
-
57
-
-
84873564101
-
Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines
-
[PMID: 23296709 DOI: 10.4049/jimmunol.1201725]
-
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, Meitzler JL, Hollingshead M, Haines DC, Butcher D, Roy K, Doroshow JH. Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines. J Immunol 2013; 190: 1859-1872 [PMID: 23296709 DOI: 10.4049/jimmunol.1201725]
-
(2013)
J Immunol
, vol.190
, pp. 1859-1872
-
-
Wu, Y.1
Lu, J.2
Antony, S.3
Juhasz, A.4
Liu, H.5
Jiang, G.6
Meitzler, J.L.7
Hollingshead, M.8
Haines, D.C.9
Butcher, D.10
Roy, K.11
Doroshow, J.H.12
-
58
-
-
73449146279
-
Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway
-
[PMID: 19722233 DOI: 10.1002/jso.21392]
-
Ikebe M, Kitaura Y, Nakamura M, Tanaka H, Yamasaki A, Nagai S, Wada J, Yanai K, Koga K, Sato N, Kubo M, Tanaka M, Onishi H, Katano M. Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. J Surg Oncol 2009; 100: 725-731 [PMID: 19722233 DOI: 10.1002/jso.21392]
-
(2009)
J Surg Oncol
, vol.100
, pp. 725-731
-
-
Ikebe, M.1
Kitaura, Y.2
Nakamura, M.3
Tanaka, H.4
Yamasaki, A.5
Nagai, S.6
Wada, J.7
Yanai, K.8
Koga, K.9
Sato, N.10
Kubo, M.11
Tanaka, M.12
Onishi, H.13
Katano, M.14
-
59
-
-
0036334059
-
Matrix metalloproteinases and their role in pancreatic cancer: A review of preclinical studies and clinical trials
-
[PMID: 12167581 DOI: 10.1007/BF02574483]
-
Bloomston M, Zervos EE, Rosemurgy AS. Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials. Ann Surg Oncol 2002; 9: 668-674 [PMID: 12167581 DOI: 10.1007/BF02574483]
-
(2002)
Ann Surg Oncol
, vol.9
, pp. 668-674
-
-
Bloomston, M.1
Zervos, E.E.2
Rosemurgy, A.S.3
-
60
-
-
77951973979
-
Primers on molecular pathways: Lipopolysaccharide signaling-potential role in pancreatitis and pancreatic cancer
-
[PMID: 20460943 DOI: 10.1159/000299987]
-
Del Pozo JL. Primers on molecular pathways: lipopolysaccharide signaling-potential role in pancreatitis and pancreatic cancer. Pancreatology 2010; 10: 114-118 [PMID: 20460943 DOI: 10.1159/000299987]
-
(2010)
Pancreatology
, vol.10
, pp. 114-118
-
-
Del Pozo, J.L.1
-
61
-
-
84879663836
-
M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway
-
[PMID: 23752129 DOI: 10.1038/labinvest. 2013.69]
-
Liu CY, Xu JY, Shi XY, Huang W, Ruan TY, Xie P, Ding JL. M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. Lab Invest 2013; 93: 844-854 [PMID: 23752129 DOI: 10.1038/labinvest. 2013.69]
-
(2013)
Lab Invest
, vol.93
, pp. 844-854
-
-
Liu, C.Y.1
Xu, J.Y.2
Shi, X.Y.3
Huang, W.4
Ruan, T.Y.5
Xie, P.6
Ding, J.L.7
-
62
-
-
77954259621
-
Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma
-
[PMID: 20556833 DOI: 10.3748/wjg.v16.i23.2881]
-
Zhang JJ, Wu HS, Wang L, Tian Y, Zhang JH, Wu HL. Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma. World J Gastroenterol 2010; 16: 2881-2888 [PMID: 20556833 DOI: 10.3748/wjg.v16.i23.2881]
-
(2010)
World J Gastroenterol
, vol.16
, pp. 2881-2888
-
-
Zhang, J.J.1
Wu, H.S.2
Wang, L.3
Tian, Y.4
Zhang, J.H.5
Wu, H.L.6
-
63
-
-
84862815577
-
Hypoxia-inducible factor-1 upregulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions
-
[PMID: 22487528 DOI: 10.1016/j.pan.2012.02.015]
-
Fan P, Zhang JJ, Wang B, Wu HQ, Zhou SX, Wang CY, Zhang JH, Tian Y, Wu HS. Hypoxia-inducible factor-1 upregulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions. Pancreatology 2012; 12: 170-178 [PMID: 22487528 DOI: 10.1016/j.pan.2012.02.015]
-
(2012)
Pancreatology
, vol.12
, pp. 170-178
-
-
Fan, P.1
Zhang, J.J.2
Wang, B.3
Wu, H.Q.4
Zhou, S.X.5
Wang, C.Y.6
Zhang, J.H.7
Tian, Y.8
Wu, H.S.9
-
64
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
[PMID: 17479101 DOI: 10.1038/nm1589]
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007; 13: 552-559 [PMID: 17479101 DOI: 10.1038/nm1589]
-
(2007)
Nat Med
, vol.13
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
65
-
-
84885831036
-
Signaling via MYD88 in the pancreatic tumor microenvironment: A double-edged sword
-
[PMID: 23483804 DOI: 10.4161/onci.22567]
-
Zambirinis CP, Miller G. Signaling via MYD88 in the pancreatic tumor microenvironment: A double-edged sword. Oncoimmunology 2013; 2: e22567 [PMID: 23483804 DOI: 10.4161/onci.22567]
-
(2013)
Oncoimmunology
, vol.2
-
-
Zambirinis, C.P.1
Miller, G.2
-
66
-
-
84876236738
-
Induction of TRIF-or MYD88-dependent pathways perturbs cell cycle regulation in pancreatic cancer
-
[PMID: 23549168 DOI: 10.4161/cc.24488]
-
Zambirinis CP, Ochi A, Barilla R, Greco S, Deutsch M, Miller G. Induction of TRIF-or MYD88-dependent pathways perturbs cell cycle regulation in pancreatic cancer. Cell Cycle 2013; 12: 1153-1154 [PMID: 23549168 DOI: 10.4161/cc.24488]
-
(2013)
Cell Cycle
, vol.12
, pp. 1153-1154
-
-
Zambirinis, C.P.1
Ochi, A.2
Barilla, R.3
Greco, S.4
Deutsch, M.5
Miller, G.6
-
67
-
-
84868627145
-
Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans
-
[PMID: 23023703 DOI: 10.1172/JCI63606]
-
Ochi A, Graffeo CS, Zambirinis CP, Rehman A, Hackman M, Fallon N, Barilla RM, Henning JR, Jamal M, Rao R, Greco S, Deutsch M, Medina-Zea MV, Bin Saeed U, Ego-Osuala MO, Hajdu C, Miller G. Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans. J Clin Invest 2012; 122: 4118-4129 [PMID: 23023703 DOI: 10.1172/JCI63606]
-
(2012)
J Clin Invest
, vol.122
, pp. 4118-4129
-
-
Ochi, A.1
Graffeo, C.S.2
Zambirinis, C.P.3
Rehman, A.4
Hackman, M.5
Fallon, N.6
Barilla, R.M.7
Henning, J.R.8
Jamal, M.9
Rao, R.10
Greco, S.11
Deutsch, M.12
Medina-Zea, M.V.13
Bin Saeed, U.14
Ego-Osuala, M.O.15
Hajdu, C.16
Miller, G.17
-
68
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
[PMID: 11130078 DOI: 10.1038/35047123]
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-745 [PMID: 11130078 DOI: 10.1038/35047123]
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
69
-
-
84863475067
-
TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism
-
[PMID: 22717578 DOI: 10.1038/cddis.2012.60]
-
Noack J, Jordi M, Zauner L, Alessi D, Burch A, Tinguely M, Hersberger M, Bernasconi M, Nadal D. TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism. Cell Death Dis 2012; 3: e323 [PMID: 22717578 DOI: 10.1038/cddis.2012.60]
-
(2012)
Cell Death Dis
, vol.3
-
-
Noack, J.1
Jordi, M.2
Zauner, L.3
Alessi, D.4
Burch, A.5
Tinguely, M.6
Hersberger, M.7
Bernasconi, M.8
Nadal, D.9
-
70
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
[PMID: 16763660 DOI: 10.1038/nrd2059]
-
Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 2006; 5: 471-484 [PMID: 16763660 DOI: 10.1038/nrd2059]
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 471-484
-
-
Krieg, A.M.1
-
71
-
-
78650601347
-
An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma
-
[PMID: 20473889 DOI: 10.1002/ijc.25399]
-
Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, Kisser U, Bauer CA, Dauer M, Eigler A, Maraskovsky E, Endres S, Schnurr M. An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma. Int J Cancer 2011; 128: 897-907 [PMID: 20473889 DOI: 10.1002/ijc.25399]
-
(2011)
Int J Cancer
, vol.128
, pp. 897-907
-
-
Jacobs, C.1
Duewell, P.2
Heckelsmiller, K.3
Wei, J.4
Bauernfeind, F.5
Ellermeier, J.6
Kisser, U.7
Bauer, C.A.8
Dauer, M.9
Eigler, A.10
Maraskovsky, E.11
Endres, S.12
Schnurr, M.13
-
72
-
-
22244438547
-
Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft
-
[PMID: 16024642 DOI: 10.1158/0008-5472.CAN-05-0602]
-
Pratesi G, Petrangolini G, Tortoreto M, Addis A, Belluco S, Rossini A, Selleri S, Rumio C, Menard S, Balsari A. Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft. Cancer Res 2005; 65: 6388-6393 [PMID: 16024642 DOI: 10.1158/0008-5472.CAN-05-0602]
-
(2005)
Cancer Res
, vol.65
, pp. 6388-6393
-
-
Pratesi, G.1
Petrangolini, G.2
Tortoreto, M.3
Addis, A.4
Belluco, S.5
Rossini, A.6
Selleri, S.7
Rumio, C.8
Menard, S.9
Balsari, A.10
-
73
-
-
0033497861
-
Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas
-
[PMID: 10615931 DOI: 10.1097/00000658-199912000-00005]. discussion 774-775
-
Friess H, Wang L, Zhu Z, Gerber R, Schröder M, Fukuda A, Zimmermann A, Korc M, Büchler MW. Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas. Ann Surg 1999; 230: 767-774; discussion 774-775 [PMID: 10615931 DOI: 10.1097/00000658-199912000-00005]
-
(1999)
Ann Surg
, vol.230
, pp. 767-774
-
-
Friess, H.1
Wang, L.2
Zhu, Z.3
Gerber, R.4
Schröder, M.5
Fukuda, A.6
Zimmermann, A.7
Korc, M.8
Büchler, M.W.9
-
74
-
-
84860267502
-
Systemic treatment of advanced pancreatic cancer
-
[PMID: 22226241 DOI: 10.1016/j.ctrv.2011.12.004]
-
Heinemann V, Haas M, Boeck S. Systemic treatment of advanced pancreatic cancer. Cancer Treat Rev 2012; 38: 843-853 [PMID: 22226241 DOI: 10.1016/j.ctrv.2011.12.004]
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 843-853
-
-
Heinemann, V.1
Haas, M.2
Boeck, S.3
-
75
-
-
4344590997
-
Cetuximab, a monoclo-nal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II Trial
-
[PMID: 15226328 DOI: 10.1200/JCO.2004.12.040]
-
Xiong HQ, Rosenberg A, LoBuglio A, Schmidt W, Wolff RA, Deutsch J, Needle M, Abbruzzese JL. Cetuximab, a monoclo-nal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II Trial. J Clin Oncol 2004; 22: 2610-2616 [PMID: 15226328 DOI: 10.1200/JCO.2004.12.040]
-
(2004)
J Clin Oncol
, vol.22
, pp. 2610-2616
-
-
Xiong, H.Q.1
Rosenberg, A.2
LoBuglio, A.3
Schmidt, W.4
Wolff, R.A.5
Deutsch, J.6
Needle, M.7
Abbruzzese, J.L.8
-
76
-
-
31544452826
-
Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors
-
[PMID: 16428503 DOI: 10.1158/1078-0432. CCR-05-1943]
-
Damiano V, Caputo R, Bianco R, D'Armiento FP, Leonardi A, De Placido S, Bianco AR, Agrawal S, Ciardiello F, Tortora G. Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors. Clin Cancer Res 2006; 12: 577-583 [PMID: 16428503 DOI: 10.1158/1078-0432. CCR-05-1943]
-
(2006)
Clin Cancer Res
, vol.12
, pp. 577-583
-
-
Damiano, V.1
Caputo, R.2
Bianco, R.3
D'Armiento, F.P.4
Leonardi, A.5
De Placido, S.6
Bianco, A.R.7
Agrawal, S.8
Ciardiello, F.9
Tortora, G.10
-
77
-
-
80054095608
-
Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers
-
[PMID: 21890455 DOI: 10.1158/1078-0432.CCR-10-3376]
-
Rosa R, Melisi D, Damiano V, Bianco R, Garofalo S, Gelardi T, Agrawal S, Di Nicolantonio F, Scarpa A, Bardelli A, Tortora G. Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers. Clin Cancer Res 2011; 17: 6531-6541 [PMID: 21890455 DOI: 10.1158/1078-0432.CCR-10-3376]
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6531-6541
-
-
Rosa, R.1
Melisi, D.2
Damiano, V.3
Bianco, R.4
Garofalo, S.5
Gelardi, T.6
Agrawal, S.7
Di Nicolantonio, F.8
Scarpa, A.9
Bardelli, A.10
Tortora, G.11
-
78
-
-
51249084219
-
DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2
-
[PMID: 18403779 DOI: 10.1165/rcmb.2007-0458OC]
-
Liu K, Anderson GP, Bozinovski S. DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2. Am J Respir Cell Mol Biol 2008; 39: 305-311 [PMID: 18403779 DOI: 10.1165/rcmb.2007-0458OC]
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 305-311
-
-
Liu, K.1
Anderson, G.P.2
Bozinovski, S.3
-
79
-
-
79955940011
-
Effects of CPG ODN on biological behavior of PANC-1 and expression of TLR9 in pancreatic cancer
-
[PMID: 21448350 DOI: 10.3748/wjg.v17.i8.996]
-
Wu HQ, Wang B, Zhu SK, Tian Y, Zhang JH, Wu HS. Effects of CPG ODN on biological behavior of PANC-1 and expression of TLR9 in pancreatic cancer. World J Gastroenterol 2011; 17: 996-1003 [PMID: 21448350 DOI: 10.3748/wjg.v17.i8.996]
-
(2011)
World J Gastroenterol
, vol.17
, pp. 996-1003
-
-
Wu, H.Q.1
Wang, B.2
Zhu, S.K.3
Tian, Y.4
Zhang, J.H.5
Wu, H.S.6
-
80
-
-
84872801225
-
Trial Watch: Experimental Toll-like receptor agonists for cancer therapy
-
[PMID: 22934262 DOI: 10.4161/onci.20696]
-
Galluzzi L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautès-Fridman C, Tartour E, Zitvogel L, Kroemer G. Trial Watch: Experimental Toll-like receptor agonists for cancer therapy. Oncoimmunology 2012; 1: 699-716 [PMID: 22934262 DOI: 10.4161/onci.20696]
-
(2012)
Oncoimmunology
, vol.1
, pp. 699-716
-
-
Galluzzi, L.1
Vacchelli, E.2
Eggermont, A.3
Fridman, W.H.4
Galon, J.5
Sautès-Fridman, C.6
Tartour, E.7
Zitvogel, L.8
Kroemer, G.9
-
81
-
-
84876807399
-
Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma
-
[PMID: 23622132 DOI: 10.1053/j.gastro.2012.12.042]
-
Zheng L, Xue J, Jaffee EM, Habtezion A. Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma. Gastroenterology 2013; 144: 1230-1240 [PMID: 23622132 DOI: 10.1053/j.gastro.2012.12.042]
-
(2013)
Gastroenterology
, vol.144
, pp. 1230-1240
-
-
Zheng, L.1
Xue, J.2
Jaffee, E.M.3
Habtezion, A.4
-
82
-
-
0023967438
-
Regional chemotherapy for colorectal cancer metastatic to the liver
-
[PMID: 3079322 DOI: 10.1158/1078-0432. CCR-10-3074]
-
Venook AP, Stagg RJ, Lewis BJ. Regional chemotherapy for colorectal cancer metastatic to the liver. Oncology (Williston Park) 1988; 2: 19-26 [PMID: 3079322 DOI: 10.1158/1078-0432. CCR-10-3074]
-
(1988)
Oncology (Williston Park)
, vol.2
, pp. 19-26
-
-
Venook, A.P.1
Stagg, R.J.2
Lewis, B.J.3
-
83
-
-
84884555918
-
Comparison of MUC4 expression in primary pancreatic cancer and paired lymph node metastases
-
[PMID: 24047396 DOI: 10.3109/00365521. 2013.832368]
-
Ansari D, Urey C, Gundewar C, Bauden MP, Andersson R. Comparison of MUC4 expression in primary pancreatic cancer and paired lymph node metastases. Scand J Gastroenterol 2013; 48: 1183-1187 [PMID: 24047396 DOI: 10.3109/00365521. 2013.832368]
-
(2013)
Scand J Gastroenterol
, vol.48
, pp. 1183-1187
-
-
Ansari, D.1
Urey, C.2
Gundewar, C.3
Bauden, M.P.4
Andersson, R.5
-
84
-
-
70249142891
-
Targeted liposomal delivery of TLR9 ligands activates spontaneous antitumor immunity in an autochthonous cancer model
-
[PMID: 19561111 DOI: 10.4049/jimmunol.0900736]
-
Hamzah J, Altin JG, Herringson T, Parish CR, Hämmerling GJ, O'Donoghue H, Ganss R. Targeted liposomal delivery of TLR9 ligands activates spontaneous antitumor immunity in an autochthonous cancer model. J Immunol 2009; 183: 1091-1098 [PMID: 19561111 DOI: 10.4049/jimmunol.0900736]
-
(2009)
J Immunol
, vol.183
, pp. 1091-1098
-
-
Hamzah, J.1
Altin, J.G.2
Herringson, T.3
Parish, C.R.4
Hämmerling, G.J.5
O'Donoghue, H.6
Ganss, R.7
-
85
-
-
79959267977
-
Toll-like receptors, inflammation, metabolism and obesity
-
[PMID: 21599616 DOI: 10.3109/13813455.2011.5 62514]
-
Fresno M, Alvarez R, Cuesta N. Toll-like receptors, inflammation, metabolism and obesity. Arch Physiol Biochem 2011; 117: 151-164 [PMID: 21599616 DOI: 10.3109/13813455.2011.5 62514]
-
(2011)
Arch Physiol Biochem
, vol.117
, pp. 151-164
-
-
Fresno, M.1
Alvarez, R.2
Cuesta, N.3
|