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Volumn 133, Issue 3, 2009, Pages 365-374

Familial pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CANCER SCREENING; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; EARLY DIAGNOSIS; FAMILIAL ATYPICAL MULTIPLE MOLE MELANOMA SYNDROME; FAMILIAL CANCER; FAMILY HISTORY; GENE MUTATION; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; PANCREAS CANCER; PEUTZ JEGHERS SYNDROME; PRECANCER; REVIEW; TUMOR SUPPRESSOR GENE;

EID: 62249117097     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (162)

References (96)
  • 1
    • 0015883612 scopus 로고
    • Adenocarcinoma of the pancreas in four siblings
    • MacDermott RP, Kramer P. Adenocarcinoma of the pancreas in four siblings. Gastroenterology. 1973;65:137-139.
    • (1973) Gastroenterology , vol.65 , pp. 137-139
    • MacDermott, R.P.1    Kramer, P.2
  • 3
    • 0029048904 scopus 로고    scopus 로고
    • Evans JP, Burke W, Chen R, et al. Familial pancreatic adenocarcinoma: association with diabetes and early molecular diagnosis. J Med Genet. 1 995;32:330-335.
    • Evans JP, Burke W, Chen R, et al. Familial pancreatic adenocarcinoma: association with diabetes and early molecular diagnosis. J Med Genet. 1 995;32:330-335.
  • 5
    • 0022470538 scopus 로고
    • Pancreatic cancer in mother and daughter
    • Katkhouda N, Mouiel J. Pancreatic cancer in mother and daughter. Lancet. 1986;2:747.
    • (1986) Lancet , vol.2 , pp. 747
    • Katkhouda, N.1    Mouiel, J.2
  • 6
    • 0020174246 scopus 로고
    • Pancreatic carcinoma in brothers
    • Dat NM, Sontag SJ. Pancreatic carcinoma in brothers. Ann Intern Med. 1982;97:282.
    • (1982) Ann Intern Med , vol.97 , pp. 282
    • Dat, N.M.1    Sontag, S.J.2
  • 7
    • 0023203470 scopus 로고
    • Cancer of the pancreas in two brothers and one sister
    • Ghadirian P, Simard A, Baillangeon J. Cancer of the pancreas in two brothers and one sister. Int J Pancreatol. 1987;2:383-391.
    • (1987) Int J Pancreatol , vol.2 , pp. 383-391
    • Ghadirian, P.1    Simard, A.2    Baillangeon, J.3
  • 8
    • 0025055664 scopus 로고
    • Familial pancreatic cancer: Clinicopathological study of 18 nuclear families
    • Lynch HT, Fitzsimmons ML, Smyrk TC. Familial pancreatic cancer: clinicopathological study of 18 nuclear families. Am J Gastroenterol. 1990;85:54-60.
    • (1990) Am J Gastroenterol , vol.85 , pp. 54-60
    • Lynch, H.T.1    Fitzsimmons, M.L.2    Smyrk, T.C.3
  • 9
    • 0026324378 scopus 로고
    • Reported family aggregation of pancreatic cancer within a population-based case-control study in the Francophone community in Montreal, Canada
    • Ghadirian P, Boyle P, Simard A, Baillargeon J, Maisonneuve P, Perret C. Reported family aggregation of pancreatic cancer within a population-based case-control study in the Francophone community in Montreal, Canada. Int J Pancreatol. 1991;10:183-196.
    • (1991) Int J Pancreatol , vol.10 , pp. 183-196
    • Ghadirian, P.1    Boyle, P.2    Simard, A.3    Baillargeon, J.4    Maisonneuve, P.5    Perret, C.6
  • 10
    • 0035182385 scopus 로고    scopus 로고
    • Risk factors for pancreatic cancer: A case-control study based on direct interviews
    • Silverman DT. Risk factors for pancreatic cancer: a case-control study based on direct interviews. Teratog Carcinog Mutagen. 2001;21:7-25.
    • (2001) Teratog Carcinog Mutagen , vol.21 , pp. 7-25
    • Silverman, D.T.1
  • 11
    • 0034536747 scopus 로고    scopus 로고
    • Predictors of pancreatic cancer mortality among a large cohort of United States adults
    • Coughlin SS, Calle EE, Patel AV, Thun MJ. Predictors of pancreatic cancer mortality among a large cohort of United States adults. Cancer Causes Control. 2000;11:915-923.
    • (2000) Cancer Causes Control , vol.11 , pp. 915-923
    • Coughlin, S.S.1    Calle, E.E.2    Patel, A.V.3    Thun, M.J.4
  • 14
    • 33845885517 scopus 로고    scopus 로고
    • Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism
    • Pogue-Geile KL, Chen R, Bronner MP, et al. Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med. 2006;3:e516.
    • (2006) PLoS Med , vol.3
    • Pogue-Geile, K.L.1    Chen, R.2    Bronner, M.P.3
  • 15
    • 33750497231 scopus 로고    scopus 로고
    • Evaluation of the 4q32-34 locus in European familial pancreatic cancer
    • Earl J, Yan L, Vitone LJ, et al. Evaluation of the 4q32-34 locus in European familial pancreatic cancer. Cancer Epidemiol Biomarkers Prev. 2006;15:1948-1955.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 1948-1955
    • Earl, J.1    Yan, L.2    Vitone, L.J.3
  • 16
    • 34548232709 scopus 로고    scopus 로고
    • Palladin is overexpressed in the nonneoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells
    • Salaria SN, Illei P, Sharma R, et al. Palladin is overexpressed in the nonneoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells. Cancer Biol Ther. 2007;6:324-328.
    • (2007) Cancer Biol Ther , vol.6 , pp. 324-328
    • Salaria, S.N.1    Illei, P.2    Sharma, R.3
  • 17
    • 34548270466 scopus 로고    scopus 로고
    • Linkage analysis of chromosome 4 in families with familial pancreatic cancer
    • Klein AP, de Andrade M, Hruban RH, et al. Linkage analysis of chromosome 4 in families with familial pancreatic cancer. Cancer Biol Ther. 2007;6(3):320-323.
    • (2007) Cancer Biol Ther , vol.6 , Issue.3 , pp. 320-323
    • Klein, A.P.1    de Andrade, M.2    Hruban, R.H.3
  • 18
    • 34247470247 scopus 로고    scopus 로고
    • Palladin mutation causes familial pancreatic cancer: Absence in European families
    • Slater E, Amrillaeva V, Fendrich V, et al. Palladin mutation causes familial pancreatic cancer: absence in European families. PLoS Med. 2007;4:e164.
    • (2007) PLoS Med , vol.4
    • Slater, E.1    Amrillaeva, V.2    Fendrich, V.3
  • 19
    • 34248185509 scopus 로고    scopus 로고
    • The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer
    • Zogopoulos G, Rothenmund H, Eppel A, et al. The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer. Hum Genet. 2007;121:635-637.
    • (2007) Hum Genet , vol.121 , pp. 635-637
    • Zogopoulos, G.1    Rothenmund, H.2    Eppel, A.3
  • 20
    • 11144353646 scopus 로고    scopus 로고
    • Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
    • Klein AP, Brune KA, Petersen GM, et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res. 2004;64:2634-2638.
    • (2004) Cancer Res , vol.64 , pp. 2634-2638
    • Klein, A.P.1    Brune, K.A.2    Petersen, G.M.3
  • 21
    • 34848873795 scopus 로고    scopus 로고
    • Validity of models for predicting BRCA1 and BRCA2 mutations
    • Parmigiani G, Chen S, Iversen ES Jr, et al. Validity of models for predicting BRCA1 and BRCA2 mutations. Ann Intern Med. 2007;147:441-450.
    • (2007) Ann Intern Med , vol.147 , pp. 441-450
    • Parmigiani, G.1    Chen, S.2    Iversen Jr, E.S.3
  • 22
    • 33749066191 scopus 로고    scopus 로고
    • Prediction of germline mutations and cancer risk in the Lynch syndrome
    • Chen S, Wang W, Lee S, et al. Prediction of germline mutations and cancer risk in the Lynch syndrome. JAMA. 2006;296:1479-1487.
    • (2006) JAMA , vol.296 , pp. 1479-1487
    • Chen, S.1    Wang, W.2    Lee, S.3
  • 23
    • 34248210562 scopus 로고    scopus 로고
    • PancPRO: Risk assessment for individuals with a family history of pancreatic cancer
    • Wang W, Chen S, Brune KA, Hruban RH, Parmigiani G, Klein AP. PancPRO: risk assessment for individuals with a family history of pancreatic cancer. J Clin Oncol. 2007;25:1417-1422.
    • (2007) J Clin Oncol , vol.25 , pp. 1417-1422
    • Wang, W.1    Chen, S.2    Brune, K.A.3    Hruban, R.H.4    Parmigiani, G.5    Klein, A.P.6
  • 24
    • 0034464147 scopus 로고    scopus 로고
    • Very high risk of cancer in familial Peutz-Jeghers syndrome
    • Giardiello FM, Brensinger JD, Tersmette AC, et al. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology. 2000;119:1447-1453.
    • (2000) Gastroenterology , vol.119 , pp. 1447-1453
    • Giardiello, F.M.1    Brensinger, J.D.2    Tersmette, A.C.3
  • 26
    • 0027294719 scopus 로고
    • Pancreatitis and the risk of pancreatic cancer
    • for The International Pancreatitis Study Group
    • Lowenfels AB, Maisonneuve P, Cavallini G, et al; for The International Pancreatitis Study Group. Pancreatitis and the risk of pancreatic cancer. N Engl J Med. 1993;328:1433-1437.
    • (1993) N Engl J Med , vol.328 , pp. 1433-1437
    • Lowenfels, A.B.1    Maisonneuve, P.2    Cavallini, G.3
  • 27
    • 10144246566 scopus 로고    scopus 로고
    • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
    • Whitcomb DC, Gorry MC, Preston RA, et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet. 1996;14:141-145.
    • (1996) Nat Genet , vol.14 , pp. 141-145
    • Whitcomb, D.C.1    Gorry, M.C.2    Preston, R.A.3
  • 28
    • 0035152551 scopus 로고    scopus 로고
    • Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreato-blastomas: Frequent alterations in the APC/beta-catenin pathway and chromosome 11p
    • Abraham SC, Wu TT, Klimstra DS, et al. Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreato-blastomas: frequent alterations in the APC/beta-catenin pathway and chromosome 11p. Am J Pathol. 2001;159:1619-1627.
    • (2001) Am J Pathol , vol.159 , pp. 1619-1627
    • Abraham, S.C.1    Wu, T.T.2    Klimstra, D.S.3
  • 29
    • 0035300547 scopus 로고    scopus 로고
    • Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability
    • Yamamoto H, Itoh F, Nakamura H, et al. Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. Cancer Res. 2001;61:3139-3144.
    • (2001) Cancer Res , vol.61 , pp. 3139-3144
    • Yamamoto, H.1    Itoh, F.2    Nakamura, H.3
  • 30
    • 0033847858 scopus 로고    scopus 로고
    • Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity
    • Wilentz RE, Goggins M, Redston M, et al. Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: a newly described and characterized entity. Am J Pathol. 2000;156:1641-1651.
    • (2000) Am J Pathol , vol.156 , pp. 1641-1651
    • Wilentz, R.E.1    Goggins, M.2    Redston, M.3
  • 31
    • 33750083369 scopus 로고    scopus 로고
    • Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene
    • Banville N, Geraghty R, Fox E, et al. Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol. 2006;37:1498-1502.
    • (2006) Hum Pathol , vol.37 , pp. 1498-1502
    • Banville, N.1    Geraghty, R.2    Fox, E.3
  • 32
    • 17644430199 scopus 로고    scopus 로고
    • Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology: Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+
    • Goggins M, Offerhaus GJ, Hilgers W, et al. Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology: poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+. Am J Pathol. 1998;152:1 501-1507.
    • (1998) Am J Pathol , vol.152 , Issue.1 , pp. 501-1507
    • Goggins, M.1    Offerhaus, G.J.2    Hilgers, W.3
  • 33
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • Su GH, Hruban RH, Bansal RK, et al. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol. 1999;154:1835-1840.
    • (1999) Am J Pathol , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3
  • 34
    • 34249915517 scopus 로고    scopus 로고
    • Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas
    • Furukawa T. Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas. J Hepatobiliary Pancreat Surg. 2007;14:233-237.
    • (2007) J Hepatobiliary Pancreat Surg , vol.14 , pp. 233-237
    • Furukawa, T.1
  • 35
    • 0035184065 scopus 로고    scopus 로고
    • STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas
    • Sato N, Rosty C, Jansen M, et al. STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol. 2001;159:2017-2022.
    • (2001) Am J Pathol , vol.159 , pp. 2017-2022
    • Sato, N.1    Rosty, C.2    Jansen, M.3
  • 36
    • 33644881658 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: Reflection on the Creighton University historical series of high risk families
    • Sinilnikova OM, Mazoyer S, Bonnardel C, Lynch HT, Narod SA, Lenoir GM. BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on the Creighton University historical series of high risk families. Fam Cancer. 2006;5:15-20.
    • (2006) Fam Cancer , vol.5 , pp. 15-20
    • Sinilnikova, O.M.1    Mazoyer, S.2    Bonnardel, C.3    Lynch, H.T.4    Narod, S.A.5    Lenoir, G.M.6
  • 38
    • 0036644884 scopus 로고    scopus 로고
    • Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
    • Murphy KM, Brune KA, Griffin C, et al. Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res. 2002;62:3789-3793.
    • (2002) Cancer Res , vol.62 , pp. 3789-3793
    • Murphy, K.M.1    Brune, K.A.2    Griffin, C.3
  • 39
    • 0034650411 scopus 로고    scopus 로고
    • Inherited predisposition to pancreatic adenocarcinoma: Role of family history and germ-line p16, BRCA1, and BRCA2 mutations
    • Lal G, Liu G, Schmocker B, et al. Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations. Cancer Res. 2000;60:409-416.
    • (2000) Cancer Res , vol.60 , pp. 409-416
    • Lal, G.1    Liu, G.2    Schmocker, B.3
  • 40
    • 12644253827 scopus 로고    scopus 로고
    • Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
    • Goggins M, Schutte M, Lu J, et al. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res. 1996;56:5360-5364.
    • (1996) Cancer Res , vol.56 , pp. 5360-5364
    • Goggins, M.1    Schutte, M.2    Lu, J.3
  • 41
    • 0037420026 scopus 로고    scopus 로고
    • BRCA2 germline mutations in familial pancreatic carcinoma
    • Hahn SA, Greenhalf B, Ellis I, et al. BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst. 2003;95:214-221.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 214-221
    • Hahn, S.A.1    Greenhalf, B.2    Ellis, I.3
  • 42
    • 0029794992 scopus 로고    scopus 로고
    • Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2
    • Roa BB, Boyd AA, Volcik K, Richards CS. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet. 1996;14:185-187.
    • (1996) Nat Genet , vol.14 , pp. 185-187
    • Roa, B.B.1    Boyd, A.A.2    Volcik, K.3    Richards, C.S.4
  • 43
    • 33846333535 scopus 로고    scopus 로고
    • Targeting Fanconi anemia/BRCA2 pathway defects in cancer: The significance of preclinical pharmacogenomic models
    • Gallmeier E, Kern SE. Targeting Fanconi anemia/BRCA2 pathway defects in cancer: the significance of preclinical pharmacogenomic models. Clin Cancer Res. 2007;13:4-10.
    • (2007) Clin Cancer Res , vol.13 , pp. 4-10
    • Gallmeier, E.1    Kern, S.E.2
  • 44
    • 27144532118 scopus 로고    scopus 로고
    • In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor
    • van der Heijden MS, Brody JR, Dezentje DA, et al. In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor. Clin Cancer Res. 2005;1 1:7508-7515.
    • (2005) Clin Cancer Res , vol.1 , Issue.1 , pp. 7508-7515
    • van der Heijden, M.S.1    Brody, J.R.2    Dezentje, D.A.3
  • 45
    • 27744568392 scopus 로고    scopus 로고
    • BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: An issue of potency
    • McCabe N, Lord CJ, Tutt AN, Martin NM, Smith GC, Ashworth A. BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency. Cancer Biol Ther. 2005;4:934-936.
    • (2005) Cancer Biol Ther , vol.4 , pp. 934-936
    • McCabe, N.1    Lord, C.J.2    Tutt, A.N.3    Martin, N.M.4    Smith, G.C.5    Ashworth, A.6
  • 46
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • Bryant HE, Schultz N, Thomas HD, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature.2005;434:913-917.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 48
    • 0037130887 scopus 로고    scopus 로고
    • Cancer Incidence in BRCA1 mutation carriers
    • Thompson D, Easton DF. Cancer Incidence in BRCA1 mutation carriers. J Natl Cancer Inst. 2002;94:1358-1365.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1358-1365
    • Thompson, D.1    Easton, D.F.2
  • 49
    • 35648984485 scopus 로고    scopus 로고
    • Association of genetic variants with pancreatic cancer
    • Skudra S, Staka A, Pukitis A, et al. Association of genetic variants with pancreatic cancer. Cancer Genet Cytogenet. 2007;179:76-78.
    • (2007) Cancer Genet Cytogenet , vol.179 , pp. 76-78
    • Skudra, S.1    Staka, A.2    Pukitis, A.3
  • 51
    • 15444350943 scopus 로고    scopus 로고
    • Increased risk for cancer in patients with the Peutz-Jeghers syndrome
    • Boardman LA, Thibodeau SN, Schaid DJ, et al. Increased risk for cancer in patients with the Peutz-Jeghers syndrome. Ann Intern Med. 1998;128:896-899.
    • (1998) Ann Intern Med , vol.128 , pp. 896-899
    • Boardman, L.A.1    Thibodeau, S.N.2    Schaid, D.J.3
  • 52
    • 0027494333 scopus 로고
    • Cancer in Peutz-Jeghers syndrome
    • Hizawa K, Iida M, Matsumoto T, et al. Cancer in Peutz-Jeghers syndrome. Cancer. 1993;72:2777-2781.
    • (1993) Cancer , vol.72 , pp. 2777-2781
    • Hizawa, K.1    Iida, M.2    Matsumoto, T.3
  • 53
    • 0024350881 scopus 로고
    • Cancer and the Peutz-Jeghers syndrome
    • Spigelman AD, Murday V, Phillips RK. Cancer and the Peutz-Jeghers syndrome. Gut. 1989;30:1588-1590.
    • (1989) Gut , vol.30 , pp. 1588-1590
    • Spigelman, A.D.1    Murday, V.2    Phillips, R.K.3
  • 54
    • 0023192463 scopus 로고
    • Increased risk of cancer in the Peutz-Jeghers syndrome
    • Giardiello FM, Welsh SB, Hamilton SR, et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med. 1987;316:1511-1514.
    • (1987) N Engl J Med , vol.316 , pp. 1511-1514
    • Giardiello, F.M.1    Welsh, S.B.2    Hamilton, S.R.3
  • 55
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • Su GH, Hruban RH, Bansal RK, et al. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol. 1999;154:1835-1840.
    • (1999) Am J Pathol , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3
  • 56
    • 0038107613 scopus 로고    scopus 로고
    • Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms
    • Sahin F, Maitra A, Argani P, et al. Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms. Mod Pathol. 2003;16:686-691.
    • (2003) Mod Pathol , vol.16 , pp. 686-691
    • Sahin, F.1    Maitra, A.2    Argani, P.3
  • 57
    • 33744775945 scopus 로고    scopus 로고
    • Screening for early pancreatic neoplasia in high-risk individuals: A prospective controlled study
    • Canto M, Goggins M, Hruban R, et al. Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study. Clin Gastroenterol Hepatol. 2006;4(6):766-781.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.6 , pp. 766-781
    • Canto, M.1    Goggins, M.2    Hruban, R.3
  • 58
    • 13344286299 scopus 로고    scopus 로고
    • The hereditary pancreatitis gene maps to long arm of chromosome 7
    • Le Bodic L, Bignon JD, Raguenes O, et al. The hereditary pancreatitis gene maps to long arm of chromosome 7. Hum Mol Genet. 1996;5:549-554.
    • (1996) Hum Mol Genet , vol.5 , pp. 549-554
    • Le Bodic, L.1    Bignon, J.D.2    Raguenes, O.3
  • 59
    • 0034039578 scopus 로고    scopus 로고
    • Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis
    • Witt H, Luck W, Hennies HC, et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet. 2000;25:213-216.
    • (2000) Nat Genet , vol.25 , pp. 213-216
    • Witt, H.1    Luck, W.2    Hennies, H.C.3
  • 60
    • 33747010658 scopus 로고    scopus 로고
    • Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
    • Teich N, Rosendahl J, Toth M, Mossner J, Sahin-Toth M. Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum Mutat. 2006;27:721-730.
    • (2006) Hum Mutat , vol.27 , pp. 721-730
    • Teich, N.1    Rosendahl, J.2    Toth, M.3    Mossner, J.4    Sahin-Toth, M.5
  • 61
    • 14244265349 scopus 로고    scopus 로고
    • Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl
    • Teich N, Nemoda Z, Kohler H, et al. Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl. Hum Mutat. 2005;25:343-347.
    • (2005) Hum Mutat , vol.25 , pp. 343-347
    • Teich, N.1    Nemoda, Z.2    Kohler, H.3
  • 62
    • 0034725697 scopus 로고    scopus 로고
    • Human cationic trypsinogen: Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis
    • Sahin-Toth M. Human cationic trypsinogen: role of Asn-21 in zymogen activation and implications in hereditary pancreatitis. J Biol Chem. 2000;275:22750-22755.
    • (2000) J Biol Chem , vol.275 , pp. 22750-22755
    • Sahin-Toth, M.1
  • 63
    • 0034687560 scopus 로고    scopus 로고
    • Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen
    • Sahin-Toth M, Toth M. Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen. Biochem Biophys Res Commun. 2000;278:286-289.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 286-289
    • Sahin-Toth, M.1    Toth, M.2
  • 64
    • 3843149424 scopus 로고    scopus 로고
    • Fibrosis of the pancreas: The initial tissue damage and the resulting pattern
    • Kloppel G, Detlefsen S, Feyerabend B. Fibrosis of the pancreas: the initial tissue damage and the resulting pattern. Virchows Arch. 2004;445:1-8.
    • (2004) Virchows Arch , vol.445 , pp. 1-8
    • Kloppel, G.1    Detlefsen, S.2    Feyerabend, B.3
  • 65
    • 34248345864 scopus 로고    scopus 로고
    • Chronic pancreatitis, pseudotumors and other tumor-like lesions
    • Kloppel G. Chronic pancreatitis, pseudotumors and other tumor-like lesions. Mod Pathol. 2007;20(suppl 1):113S-131S.
    • (2007) Mod Pathol , vol.20 , Issue.SUPPL. 1
    • Kloppel, G.1
  • 66
    • 0030975440 scopus 로고    scopus 로고
    • Hereditary pancreatitis and the risk of pancreatic cancer
    • and the International Hereditary Pancreatitis Study Group
    • Lowenfels AB, Maisonneuve P, DiMagno EP, et al; and the International Hereditary Pancreatitis Study Group. Hereditary pancreatitis and the risk of pancreatic cancer. J Natl Cancer Inst. 1997;89:442-446.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 442-446
    • Lowenfels, A.B.1    Maisonneuve, P.2    DiMagno, E.P.3
  • 67
    • 0034940538 scopus 로고    scopus 로고
    • Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis
    • Lowenfels AB, Maisonneuve P, Whitcomb DC, Lerch MM, DiMagno EP. Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis. JAMA. 2001;286:169-170.
    • (2001) JAMA , vol.286 , pp. 169-170
    • Lowenfels, A.B.1    Maisonneuve, P.2    Whitcomb, D.C.3    Lerch, M.M.4    DiMagno, E.P.5
  • 68
    • 37849029916 scopus 로고    scopus 로고
    • Risk of pancreatic adenocarcinoma in patients with hereditary pancreatitis: A national exhaustive series
    • Rebours V, Boutron-Ruault MC, Schnee M, et al. Risk of pancreatic adenocarcinoma in patients with hereditary pancreatitis: a national exhaustive series. Am J Gastroenterol. 2008;103:111-119.
    • (2008) Am J Gastroenterol , vol.103 , pp. 111-119
    • Rebours, V.1    Boutron-Ruault, M.C.2    Schnee, M.3
  • 69
    • 35348992639 scopus 로고    scopus 로고
    • The genetics of hereditary colon cancer
    • Rustgi AK. The genetics of hereditary colon cancer. Genes Dev. 2007;21:2525-2538.
    • (2007) Genes Dev , vol.21 , pp. 2525-2538
    • Rustgi, A.K.1
  • 70
    • 0035132202 scopus 로고    scopus 로고
    • Histopathological identification of colon cancer with microsatellite instability
    • Alexander J, Watanabe T, Wu TT, Rashid A, Li S, Hamilton SR. Histopathological identification of colon cancer with microsatellite instability. Am J Pathol. 2001;158:527-535.
    • (2001) Am J Pathol , vol.158 , pp. 527-535
    • Alexander, J.1    Watanabe, T.2    Wu, T.T.3    Rashid, A.4    Li, S.5    Hamilton, S.R.6
  • 71
    • 23244443650 scopus 로고    scopus 로고
    • Cancer risk in hereditary non-polyposis colorectal cancer syndrome: Later age of onset
    • Hampel H, Stephens JA, Pukkala E, et al. Cancer risk in hereditary non-polyposis colorectal cancer syndrome: later age of onset. Gastroenterology.2005;129:415-421.
    • (2005) Gastroenterology , vol.129 , pp. 415-421
    • Hampel, H.1    Stephens, J.A.2    Pukkala, E.3
  • 72
    • 0022391090 scopus 로고
    • Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: A family study
    • Lynch HT, Voorhees GJ, Lanspa SJ, McGreevy PS, Lynch JF. Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: a family study. Br J Cancer. 1985;52:271-273.
    • (1985) Br J Cancer , vol.52 , pp. 271-273
    • Lynch, H.T.1    Voorhees, G.J.2    Lanspa, S.J.3    McGreevy, P.S.4    Lynch, J.F.5
  • 73
    • 0141425732 scopus 로고    scopus 로고
    • BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: Potential therapeutic targets
    • Calhoun ES, Jones JB, Ashfaq R, et al. BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets. Am J Pathol. 2003;163:1255-1260.
    • (2003) Am J Pathol , vol.163 , pp. 1255-1260
    • Calhoun, E.S.1    Jones, J.B.2    Ashfaq, R.3
  • 74
    • 0036023411 scopus 로고    scopus 로고
    • Prognostic value of microsatellite instability in resectable pancreatic cancer
    • Nakata B, Wang YQ, Yashiro M, et al. Prognostic value of microsatellite instability in resectable pancreatic cancer. Clin Cancer Res. 2002;8:2536-2540.
    • (2002) Clin Cancer Res , vol.8 , pp. 2536-2540
    • Nakata, B.1    Wang, Y.Q.2    Yashiro, M.3
  • 75
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med. 2003;349:247-257.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 76
    • 0018123909 scopus 로고
    • Familial atypical multiple mole-melanoma syndrome
    • Lynch HT, Frichot BC III, Lynch JF. Familial atypical multiple mole-melanoma syndrome. J Med Genet. 1978;15:352-356.
    • (1978) J Med Genet , vol.15 , pp. 352-356
    • Lynch, H.T.1    Frichot III, B.C.2    Lynch, J.F.3
  • 78
    • 0033362023 scopus 로고    scopus 로고
    • A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: A maximum-likelihood combined linkage and association analysis in twins and their sibs
    • Zhu G, Duffy DL, Eldridge A, et al. A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs. Am J Hum Genet. 1999;65:483-492.
    • (1999) Am J Hum Genet , vol.65 , pp. 483-492
    • Zhu, G.1    Duffy, D.L.2    Eldridge, A.3
  • 79
    • 0036143702 scopus 로고    scopus 로고
    • Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: The familial atypical mole melanoma-pancreatic carcinoma syndrome
    • Lynch HT, Brand RE, Hogg D, et al. Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome. Cancer. 2002;94:84-96.
    • (2002) Cancer , vol.94 , pp. 84-96
    • Lynch, H.T.1    Brand, R.E.2    Hogg, D.3
  • 81
    • 10044242594 scopus 로고    scopus 로고
    • Heterogeneity of risk for melanoma and pancreatic and digestive malignancies: A melanoma case-control study
    • Rutter JL, Bromley CM, Goldstein AM, et al. Heterogeneity of risk for melanoma and pancreatic and digestive malignancies: a melanoma case-control study. Cancer. 2004;101:2809-2816.
    • (2004) Cancer , vol.101 , pp. 2809-2816
    • Rutter, J.L.1    Bromley, C.M.2    Goldstein, A.M.3
  • 82
    • 0033836334 scopus 로고    scopus 로고
    • Vasen HF, Gruis NA, Frants RR, van dV, Hille ET, Bergman W. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer. 2000;87:809-811.
    • Vasen HF, Gruis NA, Frants RR, van dV, Hille ET, Bergman W. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer. 2000;87:809-811.
  • 83
    • 0025938038 scopus 로고
    • Identification and characterization of the familial adenomatous polyposis coli gene
    • Groden J, Thliveris A, Samowitz W, et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991;66:589-600.
    • (1991) Cell , vol.66 , pp. 589-600
    • Groden, J.1    Thliveris, A.2    Samowitz, W.3
  • 84
    • 0025817880 scopus 로고
    • Identification of FAP locus genes from chromosome 5q21
    • Kinzler KW, Nilbert MC, Su LK, et al. Identification of FAP locus genes from chromosome 5q21. Science. 1991;253:661-665.
    • (1991) Science , vol.253 , pp. 661-665
    • Kinzler, K.W.1    Nilbert, M.C.2    Su, L.K.3
  • 85
    • 0027429364 scopus 로고
    • Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis
    • Giardiello FM, Offerhaus GJ, Lee DH, et al. Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis. Gut. 1993;34:1394-1396.
    • (1993) Gut , vol.34 , pp. 1394-1396
    • Giardiello, F.M.1    Offerhaus, G.J.2    Lee, D.H.3
  • 86
    • 0036719176 scopus 로고    scopus 로고
    • Intraductal papillary and mucinous pancreatic tumour: A new extracolonic tumour in familial adenomatous polyposis
    • Maire F, Hammel P, Terris B, et al. Intraductal papillary and mucinous pancreatic tumour: a new extracolonic tumour in familial adenomatous polyposis. Gut. 2002;51:446-449.
    • (2002) Gut , vol.51 , pp. 446-449
    • Maire, F.1    Hammel, P.2    Terris, B.3
  • 87
    • 33846556098 scopus 로고    scopus 로고
    • Pancreatoblastoma
    • Saif MW. Pancreatoblastoma. JOP. 2007;8:55-63.
    • (2007) JOP , vol.8 , pp. 55-63
    • Saif, M.W.1
  • 88
    • 62249212345 scopus 로고    scopus 로고
    • Surveillance Epidemiology, and End Results (SEER) Program. SEER 1973-2000 public use database. SEER*Stat database: incidence-SEER 9 Regs, Nov 2002 Sub (1973-2000). Released April 2003. Bethesda, MD: National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch; 2003.
    • Surveillance Epidemiology, and End Results (SEER) Program. SEER 1973-2000 public use database. SEER*Stat database: incidence-SEER 9 Regs, Nov 2002 Sub (1973-2000). Released April 2003. Bethesda, MD: National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch; 2003.
  • 89
    • 3042525898 scopus 로고    scopus 로고
    • Screening for pancreatic neoplasia in high-risk individuals: An EUS-based approach
    • Canto MI, Goggins M, Yeo CJ, et al. Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach. Clin Gastroenterol. Hepatol.2004;2:606-621.
    • (2004) Clin Gastroenterol. Hepatol , vol.2 , pp. 606-621
    • Canto, M.I.1    Goggins, M.2    Yeo, C.J.3
  • 90
    • 33748056792 scopus 로고    scopus 로고
    • Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer
    • Brune K, Abe T, Canto M, et al. Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer. Am J Surg Pathol. 2006;30:1067-1076.
    • (2006) Am J Surg Pathol , vol.30 , pp. 1067-1076
    • Brune, K.1    Abe, T.2    Canto, M.3
  • 92
    • 0023807240 scopus 로고
    • Life-style risk factors for pancreatic cancer in Louisiana: A case-control study
    • Falk RT, Pickle LW, Fontham ET, Correa P, Fraumeni JF. Life-style risk factors for pancreatic cancer in Louisiana: a case-control study. Am J Epidemiol. 1988;128:324-336.
    • (1988) Am J Epidemiol , vol.128 , pp. 324-336
    • Falk, R.T.1    Pickle, L.W.2    Fontham, E.T.3    Correa, P.4    Fraumeni, J.F.5
  • 94
    • 36549023912 scopus 로고    scopus 로고
    • Risk factors for pancreatic cancer: Case-control study
    • Hassan MM, Bondy ML, Wolff RA, et al. Risk factors for pancreatic cancer: case-control study. Am J Gastroenterol. 2007;102:2696-2707.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2696-2707
    • Hassan, M.M.1    Bondy, M.L.2    Wolff, R.A.3
  • 95
    • 0037512364 scopus 로고    scopus 로고
    • Epidemiology of pancreatic cancer in Japan: A nested case-control study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC)
    • Inoue M, Tajima K, Takezaki T, et al. Epidemiology of pancreatic cancer in Japan: a nested case-control study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC). Int J Epidemiol. 2003;32:257-262.
    • (2003) Int J Epidemiol , vol.32 , pp. 257-262
    • Inoue, M.1    Tajima, K.2    Takezaki, T.3
  • 96
    • 0037428656 scopus 로고    scopus 로고
    • Familial and second primary pancreatic cancers: A nationwide epidemiologic study from Sweden
    • Hemminki K, Li X. Familial and second primary pancreatic cancers: a nationwide epidemiologic study from Sweden. Int J Cancer. 2003;103:525-530.
    • (2003) Int J Cancer , vol.103 , pp. 525-530
    • Hemminki, K.1    Li, X.2


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