-
1
-
-
77956289824
-
Toll-like receptors in inflammatory bowel diseases: A decade later
-
E. Cario Toll-like receptors in inflammatory bowel diseases: a decade later Inflamm Bowel Dis 16 2010 1583 1597
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1583-1597
-
-
Cario, E.1
-
2
-
-
0035793372
-
Molecular analysis of commensal host-microbial relationships in the intestine
-
DOI 10.1126/science.291.5505.881
-
L.V. Hooper, M.H. Wong, and A. Thelin Molecular analysis of commensal host-microbial relationships in the intestine Science 291 2001 881 884 (Pubitemid 32120760)
-
(2001)
Science
, vol.291
, Issue.5505
, pp. 881-884
-
-
Hooper, L.V.1
Wong, M.H.2
Thelin, A.3
Hansson, L.4
Falk, P.G.5
Gordon, J.I.6
-
3
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
S. Wu, K.J. Rhee, and E. Albesiano A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses Nat Med 15 2009 1016 1022
-
(2009)
Nat Med
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
-
4
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
DOI 10.1128/IAI.68.12.7010-7017.2000
-
E. Cario, and D.K. Podolsky Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease Infect Immun 68 2000 7010 7017 (Pubitemid 32463415)
-
(2000)
Infection and Immunity
, vol.68
, Issue.12
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
5
-
-
33646055526
-
Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance
-
E. Cario, D.T. Golenbock, and A. Visintin Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance J Immunol 176 2006 4258 4266 (Pubitemid 44264405)
-
(2006)
Journal of Immunology
, vol.176
, Issue.7
, pp. 4258-4266
-
-
Cario, E.1
Golenbock, D.T.2
Visintin, A.3
Runzi, M.4
Gerken, G.5
Podolsky, D.K.6
-
6
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
-
S. Rakoff-Nahoum, J. Paglino, and F. Eslami-Varzaneh Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis Cell 118 2004 229 241 (Pubitemid 38962578)
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
7
-
-
33748271299
-
Cox-2 Is Regulated by Toll-Like Receptor-4 (TLR4) Signaling: Role in Proliferation and Apoptosis in the Intestine
-
DOI 10.1053/j.gastro.2006.06.017, PII S001650850601287X
-
M. Fukata, A. Chen, and A. Klepper Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine Gastroenterology 131 2006 862 877 (Pubitemid 44316821)
-
(2006)
Gastroenterology
, vol.131
, Issue.3
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
Krishnareddy, S.4
Vamadevan, A.S.5
Thomas, L.S.6
Xu, R.7
Inoue, H.8
Arditi, M.9
Dannenberg, A.J.10
Abreu, M.T.11
-
8
-
-
36749054015
-
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
-
DOI 10.1073/pnas.0704828104
-
B. Ferwerda, M.B. McCall, and S. Alonso TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans Proc Natl Acad Sci U S A 104 2007 16645 16650 (Pubitemid 350211070)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.42
, pp. 16645-16650
-
-
Ferwerda, B.1
McCall, M.B.B.2
Alonso, S.3
Giamarellos-Bourboulis, E.J.4
Mouktaroudi, M.5
Izagirre, N.6
Syafruddin, D.7
Kibiki, G.8
Cristea, T.9
Hijmans, A.10
Hamann, L.11
Israel, S.12
Elghazali, G.13
Troye-Blomberg, M.14
Kumpf, O.15
Maiga, B.16
Dolo, A.17
Doumbo, O.18
Hermsen, C.C.19
Stalenhoef, A.F.H.20
Van Crevel, R.21
Brunner, H.G.22
Oh, D.-Y.23
Schumann, R.R.24
De La Rua, C.25
Sauerwein, R.26
Kullberg, B.-J.27
Van Der Ven, A.J.A.M.28
Van Der Meer, J.W.M.29
Netea, M.G.30
more..
-
9
-
-
34548222514
-
Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
-
DOI 10.1016/j.cell.2007.08.002, PII S0092867407010215
-
H.M. Kim, B.S. Park, and J.I. Kim Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran Cell 130 2007 906 917 (Pubitemid 47332573)
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 906-917
-
-
Kim, H.M.1
Park, B.S.2
Kim, J.-I.3
Kim, S.E.4
Lee, J.5
Oh, S.C.6
Enkhbayar, P.7
Matsushima, N.8
Lee, H.9
Yoo, O.J.10
Lee, J.-O.11
-
10
-
-
33745305542
-
Analysis of TLR4 polymorphic variants: New insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling
-
P. Rallabhandi, J. Bell, and M.S. Boukhvalova Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling J Immunol 177 2006 322 332 (Pubitemid 43939144)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 322-332
-
-
Rallabhandi, P.1
Bell, J.2
Boukhvalova, M.S.3
Medvedev, A.4
Lorenz, E.5
Arditi, M.6
Hemming, V.G.7
Blanco, J.C.G.8
Segal, D.M.9
Vogel, S.N.10
-
11
-
-
77952774380
-
Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4
-
P. Prohinar, P. Rallabhandi, and J.P. Weiss Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4 J Immunol 184 2010 4362 4367
-
(2010)
J Immunol
, vol.184
, pp. 4362-4367
-
-
Prohinar, P.1
Rallabhandi, P.2
Weiss, J.P.3
-
12
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
E. Lorenz, J.P. Mira, and K.L. Frees Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock Arch Intern Med 162 2002 1028 1032 (Pubitemid 34492532)
-
(2002)
Archives of Internal Medicine
, vol.162
, Issue.9
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
13
-
-
33947304959
-
A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors
-
DOI 10.1053/j.gastro.2006.12.026, PII S001650850602676X
-
G.L. Hold, C.S. Rabkin, and W.H. Chow A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors Gastroenterology 132 2007 905 912 (Pubitemid 46440859)
-
(2007)
Gastroenterology
, vol.132
, Issue.3
, pp. 905-912
-
-
Hold, G.L.1
Rabkin, C.S.2
Chow, W.3
Smith, M.G.4
Gammon, M.D.5
Risch, H.A.6
Vaughan, T.L.7
McColl, K.E.L.8
Lissowska, J.9
Zatonski, W.10
Schoenberg, J.B.11
Blot, W.J.12
Mowat, N.A.G.13
Fraumeni Jr., J.F.14
El-Omar, E.M.15
-
14
-
-
34547459989
-
The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases
-
DOI 10.1038/sj.gene.6364398, PII 6364398
-
P.L. De Jager, D. Franchimont, and A. Waliszewska The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases Genes Immun 8 2007 387 397 (Pubitemid 47163102)
-
(2007)
Genes and Immunity
, vol.8
, Issue.5
, pp. 387-397
-
-
De Jager, P.L.1
Franchimont, D.2
Waliszewska, A.3
Bitton, A.4
Cohen, A.5
Langelier, D.6
Belaiche, J.7
Vermeire, S.8
Farwell, L.9
Goris, A.10
Libioulle, C.11
Jani, N.12
Dassopoulos, T.13
Bromfield, G.P.14
Dubois, B.15
Cho, J.H.16
Brant, S.R.17
Duerr, R.H.18
Yang, H.19
Rotter, J.I.20
Silverberg, M.S.21
Steinhart, A.H.22
Daly, M.J.23
Podolsky, D.K.24
Louis, E.25
Hafler, D.A.26
Rioux, J.D.27
more..
-
15
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
DOI 10.1038/76048
-
N.C. Arbour, E. Lorenz, and B.C. Schutte TLR4 mutations are associated with endotoxin hyporesponsiveness in humans Nat Genet 25 2000 187 191 (Pubitemid 30394990)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 187-191
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
Zabner, J.4
Kline, J.N.5
Jones, M.6
Frees, K.7
Watt, J.L.8
Schwartz, D.A.9
-
16
-
-
69249109191
-
TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury
-
B. Ey, A. Eyking, and G. Gerken TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury J Biol Chem 284 2009 22332 22343
-
(2009)
J Biol Chem
, vol.284
, pp. 22332-22343
-
-
Ey, B.1
Eyking, A.2
Gerken, G.3
-
17
-
-
0037127309
-
MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
-
DOI 10.1074/jbc.M109910200
-
J. da Silva Correia, and R.J. Ulevitch MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor J Biol Chem 277 2002 1845 1854 (Pubitemid 34968758)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.3
, pp. 1845-1854
-
-
Da Silva Correia, J.1
Ulevitch, R.J.2
-
18
-
-
0029828745
-
Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
-
DOI 10.1126/science.274.5285.262
-
H. Mashimo, D.C. Wu, and D.K. Podolsky Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor Science 274 1996 262 265 (Pubitemid 26353206)
-
(1996)
Science
, vol.274
, Issue.5285
, pp. 262-265
-
-
Mashimo, H.1
Wu, D.-C.2
Podolsky, D.K.3
Fishman, M.C.4
-
19
-
-
67649231565
-
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency
-
D.K. Podolsky, G. Gerken, and A. Eyking Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency Gastroenterology 137 2009 209 220
-
(2009)
Gastroenterology
, vol.137
, pp. 209-220
-
-
Podolsky, D.K.1
Gerken, G.2
Eyking, A.3
-
20
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat Rev Cancer 2 2002 442 454
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
21
-
-
33846026749
-
Wnt/β-catenin signaling is a normal physiological response to mechanical loading in bone
-
DOI 10.1074/jbc.M602308200
-
J.A. Robinson, M. Chatterjee-Kishore, and P.J. Yaworsky Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone J Biol Chem 281 2006 31720 31728 (Pubitemid 46043263)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.42
, pp. 31720-31728
-
-
Robinson, J.A.1
Chatterjee-Kishore, M.2
Yaworsky, P.J.3
Cullen, D.M.4
Zhao, W.5
Li, C.6
Kharode, Y.7
Sauter, L.8
Babij, P.9
Brown, E.L.10
Hill, A.A.11
Akhter, M.P.12
Johnson, M.L.13
Recker, R.R.14
Komm, B.S.15
Bex, F.J.16
-
22
-
-
0037173718
-
Connexin 43, but not connexin 32, is mutated at advanced stages of human sporadic colon cancer
-
M.V. Dubina, N.A. Iatckii, and D.E. Popov Connexin 43, but not connexin 32, is mutated at advanced stages of human sporadic colon cancer Oncogene 21 2002 4992 4996
-
(2002)
Oncogene
, vol.21
, pp. 4992-4996
-
-
Dubina, M.V.1
Iatckii, N.A.2
Popov, D.E.3
-
23
-
-
23844445451
-
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
-
DOI 10.1038/nm1282
-
B.J. Jenkins, D. Grail, and T. Nheu Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling Nat Med 11 2005 845 852 (Pubitemid 41161116)
-
(2005)
Nature Medicine
, vol.11
, Issue.8
, pp. 845-852
-
-
Jenkins, B.J.1
Grail, D.2
Nheu, T.3
Najdovska, M.4
Wang, B.5
Waring, P.6
Inglese, M.7
McLoughlin, R.M.8
Jones, S.A.9
Topley, N.10
Baumann, H.11
Judd, L.M.12
Giraud, A.S.13
Boussioutas, A.14
Zhu, H.-J.15
Ernst, M.16
-
24
-
-
0027216065
-
Human Caco-2 cells transfected with c-Ha-Ras as a model for endocrine differentiation in the large intestine
-
A.P. de Bruine, J.E. de Vries, and W.N. Dinjens Human Caco-2 cells transfected with c-Ha-Ras as a model for endocrine differentiation in the large intestine Differentiation 53 1993 51 60 (Pubitemid 23182157)
-
(1993)
Differentiation
, vol.53
, Issue.1
, pp. 51-60
-
-
De Bruine, A.P.1
De Vries, J.E.2
Dinjens, W.N.M.3
Moerkerk, P.T.4
Linden, E.P.M.5
Pijls, M.M.J.6
Ten Kate, J.7
Bosman, F.T.8
-
26
-
-
35848942606
-
Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro
-
DOI 10.1091/mbc.E07-04-0308
-
J.M. Halbleib, A.M. Saaf, and P.O. Brown Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro Mol Biol Cell 18 2007 4261 4278 (Pubitemid 350060157)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.11
, pp. 4261-4278
-
-
Halbleib, J.M.1
Saaf, A.M.2
Brown, P.O.3
Nelson, W.J.4
-
27
-
-
35848935648
-
Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer
-
DOI 10.1091/mbc.E07-04-0309
-
A.M. Saaf, J.M. Halbleib, and X. Chen Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer Mol Biol Cell 18 2007 4245 4260 (Pubitemid 350060156)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.11
, pp. 4245-4260
-
-
Saaf, A.M.1
Halbleib, J.M.2
Chen, X.3
Siu, T.Y.4
Suet, Y.L.5
Nelson, W.J.6
Brown, P.O.7
-
28
-
-
27644573915
-
Macrodissection versus microdissection of rectal carcinoma: Minor influence of stroma cells to tumor cell gene expression profiles
-
E.C. de Bruin, S. van de Pas, and E.H. Lips Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles BMC Genomics 6 2005 142
-
(2005)
BMC Genomics
, vol.6
, pp. 142
-
-
De Bruin, E.C.1
Van De Pas, S.2
Lips, E.H.3
-
29
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
H. Yu, D. Pardoll, and R. Jove STATs in cancer inflammation and immunity: a leading role for STAT3 Nat Rev Cancer 9 2009 798 809
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
30
-
-
4644261307
-
The STAT3 isoforms α and β have unique and specific functions
-
DOI 10.1038/ni1052
-
D. Maritano, M.L. Sugrue, and S. Tininini The STAT3 isoforms alpha and beta have unique and specific functions Nat Immunol 5 2004 401 409 (Pubitemid 38500089)
-
(2004)
Nature Immunology
, vol.5
, Issue.4
, pp. 401-409
-
-
Maritano, D.1
Sugrue, M.L.2
Tininini, S.3
Dewilde, S.4
Strobl, B.5
Fu, X.P.6
Murray-Tait, V.7
Chiarle, R.8
Poli, V.9
-
31
-
-
0036199628
-
Stat3 controls cell movements during zebrafish gastrulation
-
DOI 10.1016/S1534-5807(02)00126-0
-
S. Yamashita, C. Miyagi, and A. Carmany-Rampey Stat3 controls cell movements during zebrafish gastrulation Dev Cell 2 2002 363 375 (Pubitemid 34266120)
-
(2002)
Developmental Cell
, vol.2
, Issue.3
, pp. 363-375
-
-
Yamashita, S.1
Miyagi, C.2
Carmany-Rampey, A.3
Shimizu, T.4
Fujii, R.5
Schier, A.F.6
Hirano, T.7
-
32
-
-
6344275527
-
The complex of ciliary neurotrophic factor-ciliary neurotrophic factor receptor α up-regulates connexin43 and intercellular coupling in astrocytes via the Janus tyrosine kinase/signal transducer and activator of transcription pathway
-
DOI 10.1091/mbc.E04-03-0271
-
M.A. Ozog, S.M. Bernier, and D.C. Bates The complex of ciliary neurotrophic factor-ciliary neurotrophic factor receptor alpha up-regulates connexin43 and intercellular coupling in astrocytes via the Janus tyrosine kinase/signal transducer and activator of transcription pathway Mol Biol Cell 15 2004 4761 4774 (Pubitemid 39392194)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.11
, pp. 4761-4774
-
-
Ozog, M.A.1
Bernier, S.M.2
Bates, D.C.3
Chatterjee, B.4
Lo, C.W.5
Naus, C.C.G.6
-
33
-
-
36549082403
-
Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
-
M. Fukata, A. Chen, and A.S. Vamadevan Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors Gastroenterology 133 2007 1869 1881
-
(2007)
Gastroenterology
, vol.133
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
-
34
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18
-
R. Salcedo, A. Worschech, and M. Cardone MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18 J Exp Med 207 2010 1625 1636
-
(2010)
J Exp Med
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
-
35
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
DOI 10.1126/science.1140488
-
S. Rakoff-Nahoum, and R. Medzhitov Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88 Science 317 2007 124 127 (Pubitemid 47056471)
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
36
-
-
77953196709
-
ERK activation drives intestinal tumorigenesis in Apc(min/+) mice
-
S.H. Lee, L.L. Hu, and J. Gonzalez-Navajas ERK activation drives intestinal tumorigenesis in Apc(min/+) mice Nat Med 16 2010 665 670
-
(2010)
Nat Med
, vol.16
, pp. 665-670
-
-
Lee, S.H.1
Hu, L.L.2
Gonzalez-Navajas, J.3
|