DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2

American Journal of Respiratory Cell and Molecular Biology

Volumn 39, Issue 3, 2008, Pages 305-311

  Liu, Kenneth ^a   Anderson, Gary P ^a   Bozinovski, Steven ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Bronchial epithelium; Epidermal growth factor receptor; Gene therapy; Inflammation

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; COLONY STIMULATING FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOTEICHOIC ACID; MESSENGER RNA; PLASMID DNA; POLYSACCHARIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; DNA; LIPOSOME; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; DNA METHYLATION; DNA VECTOR; EPITHELIUM CELL; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN CELL; INFLAMMATION; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; BRONCHITIS; CELL LINE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENE TRANSFER; GENE VECTOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; PLASMID; POLYMERASE CHAIN REACTION; RESPIRATORY TRACT MUCOSA;

BACTERIA (MICROORGANISMS);

BRONCHITIS; CELL LINE; CPG ISLANDS; DNA; DNA METHYLATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; INTERLEUKIN-8; LIPOSOMES; PLASMIDS; POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 51249084219     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2007-0458OC     Document Type: Article

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