Dual regulatory switch confers tighter control on HtrA2 proteolytic activity

FEBS Journal

Volumn 281, Issue 10, 2014, Pages 2456-2470

  Singh, Nitu ^a   D'Souza, Areetha ^a,c   Cholleti, Anuradha ^b   Sastry, G Madhavi ^b   Bose, Kakoli ^a  

^a TATA MEMORIAL HOSPITAL   (India)

^b SCHRÖDINGER INC   (United States)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

allostery; IAP; N terminus; PDZ; serine protease

Indexed keywords

SERINE PROTEINASE OMI; X LINKED INHIBITOR OF APOPTOSIS;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MECHANISM; ENZYME REGULATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

ALLOSTERY; IAP; N-TERMINUS; PDZ; SERINE PROTEASE;

ALLOSTERIC REGULATION; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA PROTEINS; ENZYME ACTIVATION; HUMANS; KINETICS; LIGANDS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PDZ DOMAINS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84901199293     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12799     Document Type: Article

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