Intricate structural coordination and domain plasticity regulate activity of serine protease HtrA2

FASEB Journal

Volumn 27, Issue 8, 2013, Pages 3054-3066

  Chaganti, Lalith K ^a   Kuppili, Raja Reddy ^a   Bose, Kakoli ^a  

^a TATA MEMORIAL HOSPITAL   (India)

Author keywords

Dynamics; PDZ; Serine protease domain

Indexed keywords

PDZ PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE OMI; CASEIN; MITOCHONDRIAL PROTEIN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; ENZYMOLOGY; MOLECULAR DYNAMICS; NEOPLASM; NONHUMAN; OLIGOMERIZATION; PDZ DOMAIN; PLASTICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; REGULATORY MECHANISM; SPECTROSCOPY; BINDING SITE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; ENZYME ACTIVATION; ENZYME SPECIFICITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETICS; HUMAN; KINETICS; METABOLISM; MUTATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

BINDING SITES; BIOCATALYSIS; CASEINS; CATALYTIC DOMAIN; CIRCULAR DICHROISM; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; KINETICS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; PDZ DOMAINS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84881175234     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-227256     Document Type: Article

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