Allosteric Regulation of Serine Protease HtrA2 through Novel Non-Canonical Substrate Binding Pocket

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Bejugam, Pruthvi Raj ^a   Kuppili, Raja R ^a   Singh, Nitu ^a   Gadewal, Nikhil ^a   Chaganti, Lalith K ^a   Sastry, G Madhavi ^b   Bose, Kakoli ^a  

^a TATA MEMORIAL HOSPITAL   (India)

^b SCHRÖDINGER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SERINE PROTEINASE OMI;

ALLOSTERISM; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; HUMANS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; PDZ DOMAINS; PEPTIDES; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES;

EID: 84874005287     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055416     Document Type: Article

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