The systemic amyloid precursor transthyretin (TTR)behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice

Journal of Neuroscience

Volumn 34, Issue 21, 2014, Pages 7253-7265

  Wang, Xin ^a   Cattaneo, Francesca ^a,b   Ryno, Lisa ^a   Hulleman, John ^a   Reixach, Natàlia ^a   Buxbaum, Joel N ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

Alzheimer's disease; Celastrol; Heat shock; HSF1; Transgenics; Transthyretin

Indexed keywords

CELASTROL; DNA FRAGMENT; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK TRANSCRIPTION FACTOR 1; PREALBUMIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CHEMOLUMINESCENCE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; GENOMICS; HEAT SHOCK; HIPPOCAMPUS; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; LUMINESCENCE ASSAY; MOUSE; NERVE CELL; NEUROBLASTOMA; NONHUMAN; PLASMID; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ALZHEIMER'S DISEASE; CELASTROL; HEAT SHOCK; HSF1; TRANSGENICS; TRANSTHYRETIN;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HIPPOCAMPUS; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROBLASTOMA; NEURONS; OLIGONUCLEOTIDES, ANTISENSE; PREALBUMIN; TRANSCRIPTION FACTORS;

EID: 84901020345     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4936-13.2014     Document Type: Article

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