메뉴 건너뛰기




Volumn 82, Issue 4, 2014, Pages 797-808

Chemogenetic Synaptic Silencing of Neural Circuits Localizes a Hypothalamus→Midbrain Pathway for Feeding Behavior

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE N OXIDE; GI PROTEIN COUPLED RECEPTOR HM4D; GUANINE NUCLEOTIDE BINDING PROTEIN; NEUREXIN; RECEPTOR; UNCLASSIFIED DRUG;

EID: 84901009992     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2014.04.008     Document Type: Article
Times cited : (326)

References (49)
  • 1
    • 79951992387 scopus 로고    scopus 로고
    • AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
    • Aponte Y., Atasoy D., Sternson S.M. AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat. Neurosci. 2011, 14:351-355.
    • (2011) Nat. Neurosci. , vol.14 , pp. 351-355
    • Aponte, Y.1    Atasoy, D.2    Sternson, S.M.3
  • 2
    • 34247640671 scopus 로고    scopus 로고
    • Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
    • Armbruster B.N., Li X., Pausch M.H., Herlitze S., Roth B.L. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc. Natl. Acad. Sci. USA 2007, 104:5163-5168.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5163-5168
    • Armbruster, B.N.1    Li, X.2    Pausch, M.H.3    Herlitze, S.4    Roth, B.L.5
  • 3
    • 49049099862 scopus 로고    scopus 로고
    • A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping
    • Atasoy D., Aponte Y., Su H.H., Sternson S.M. A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J.Neurosci. 2008, 28:7025-7030.
    • (2008) J.Neurosci. , vol.28 , pp. 7025-7030
    • Atasoy, D.1    Aponte, Y.2    Su, H.H.3    Sternson, S.M.4
  • 4
    • 84864711337 scopus 로고    scopus 로고
    • Deconstruction of a neural circuit for hunger
    • Atasoy D., Betley J.N., Su H.H., Sternson S.M. Deconstruction of a neural circuit for hunger. Nature 2012, 488:172-177.
    • (2012) Nature , vol.488 , pp. 172-177
    • Atasoy, D.1    Betley, J.N.2    Su, H.H.3    Sternson, S.M.4
  • 6
    • 70350417360 scopus 로고    scopus 로고
    • Axonal targeting of Caspr2 in hippocampal neurons via selective somatodendritic endocytosis
    • Bel C., Oguievetskaia K., Pitaval C., Goutebroze L., Faivre-Sarrailh C. Axonal targeting of Caspr2 in hippocampal neurons via selective somatodendritic endocytosis. J.Cell Sci. 2009, 122:3403-3413.
    • (2009) J.Cell Sci. , vol.122 , pp. 3403-3413
    • Bel, C.1    Oguievetskaia, K.2    Pitaval, C.3    Goutebroze, L.4    Faivre-Sarrailh, C.5
  • 7
    • 0035853270 scopus 로고    scopus 로고
    • G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry
    • Blackmer T., Larsen E.C., Takahashi M., Martin T.F., Alford S., Hamm H.E. G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry. Science 2001, 292:293-297.
    • (2001) Science , vol.292 , pp. 293-297
    • Blackmer, T.1    Larsen, E.C.2    Takahashi, M.3    Martin, T.F.4    Alford, S.5    Hamm, H.E.6
  • 9
    • 68649090485 scopus 로고    scopus 로고
    • Presynaptic signal transduction pathways that modulate synaptic transmission
    • de Jong A.P., Verhage M. Presynaptic signal transduction pathways that modulate synaptic transmission. Curr. Opin. Neurobiol. 2009, 19:245-253.
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 245-253
    • de Jong, A.P.1    Verhage, M.2
  • 10
    • 0030003658 scopus 로고    scopus 로고
    • Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse
    • Dittman J.S., Regehr W.G. Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse. J.Neurosci. 1996, 16:1623-1633.
    • (1996) J.Neurosci. , vol.16 , pp. 1623-1633
    • Dittman, J.S.1    Regehr, W.G.2
  • 11
    • 0030919664 scopus 로고    scopus 로고
    • Heterogeneity of release probability, facilitation, and depletion at central synapses
    • Dobrunz L.E., Stevens C.F. Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron 1997, 18:995-1008.
    • (1997) Neuron , vol.18 , pp. 995-1008
    • Dobrunz, L.E.1    Stevens, C.F.2
  • 12
    • 0031876072 scopus 로고    scopus 로고
    • The effects of brucine and alcuronium on the inhibition of [3H]acetylcholine release from rat striatum by muscarinic receptor agonists
    • Dolezal V., Tucek S. The effects of brucine and alcuronium on the inhibition of [3H]acetylcholine release from rat striatum by muscarinic receptor agonists. Br. J. Pharmacol. 1998, 124:1213-1218.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 1213-1218
    • Dolezal, V.1    Tucek, S.2
  • 13
    • 0035005706 scopus 로고    scopus 로고
    • The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences
    • Donnelly M.L., Hughes L.E., Luke G., Mendoza H., ten Dam E., Gani D., Ryan M.D. The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences. J.Gen. Virol. 2001, 82:1027-1041.
    • (2001) J.Gen. Virol. , vol.82 , pp. 1027-1041
    • Donnelly, M.L.1    Hughes, L.E.2    Luke, G.3    Mendoza, H.4    ten Dam, E.5    Gani, D.6    Ryan, M.D.7
  • 15
    • 0027421365 scopus 로고
    • Injecting 5-HT into the PVN does not prevent feeding induced by injecting 8-OH-DPAT into the raphe
    • Fletcher P.J., Coscina D.V. Injecting 5-HT into the PVN does not prevent feeding induced by injecting 8-OH-DPAT into the raphe. Pharmacol. Biochem. Behav. 1993, 46:487-491.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 487-491
    • Fletcher, P.J.1    Coscina, D.V.2
  • 16
    • 77949413839 scopus 로고    scopus 로고
    • Paraventricular hypothalamic nucleus: axonal projections to the brainstem
    • Geerling J.C., Shin J.W., Chimenti P.C., Loewy A.D. Paraventricular hypothalamic nucleus: axonal projections to the brainstem. J.Comp. Neurol. 2010, 518:1460-1499.
    • (2010) J.Comp. Neurol. , vol.518 , pp. 1460-1499
    • Geerling, J.C.1    Shin, J.W.2    Chimenti, P.C.3    Loewy, A.D.4
  • 17
    • 81155154245 scopus 로고    scopus 로고
    • Serotonergic anti-obesity agents: past experience and future prospects
    • Halford J.C., Boyland E.J., Lawton C.L., Blundell J.E., Harrold J.A. Serotonergic anti-obesity agents: past experience and future prospects. Drugs 2011, 71:2247-2255.
    • (2011) Drugs , vol.71 , pp. 2247-2255
    • Halford, J.C.1    Boyland, E.J.2    Lawton, C.L.3    Blundell, J.E.4    Harrold, J.A.5
  • 18
    • 79251565513 scopus 로고    scopus 로고
    • Multiple targets of μ-opioid receptor-mediated presynaptic inhibition at primary afferent Aδ- and C-fibers
    • Heinke B., Gingl E., Sandkühler J. Multiple targets of μ-opioid receptor-mediated presynaptic inhibition at primary afferent Aδ- and C-fibers. J.Neurosci. 2011, 31:1313-1322.
    • (2011) J.Neurosci. , vol.31 , pp. 1313-1322
    • Heinke, B.1    Gingl, E.2    Sandkühler, J.3
  • 19
    • 0023092620 scopus 로고
    • The GTP-binding protein, Go, regulates neuronal calcium channels
    • Hescheler J., Rosenthal W., Trautwein W., Schultz G. The GTP-binding protein, Go, regulates neuronal calcium channels. Nature 1987, 325:445-447.
    • (1987) Nature , vol.325 , pp. 445-447
    • Hescheler, J.1    Rosenthal, W.2    Trautwein, W.3    Schultz, G.4
  • 20
    • 0023619438 scopus 로고
    • Opioid receptor subtypes associated with ventral tegmental facilitation and periaqueductal gray inhibition of feeding
    • Jenck F., Quirion R., Wise R.A. Opioid receptor subtypes associated with ventral tegmental facilitation and periaqueductal gray inhibition of feeding. Brain Res. 1987, 423:39-44.
    • (1987) Brain Res. , vol.423 , pp. 39-44
    • Jenck, F.1    Quirion, R.2    Wise, R.A.3
  • 21
    • 84885594437 scopus 로고    scopus 로고
    • The inhibitory circuit architecture of the lateral hypothalamus orchestrates feeding
    • Jennings J.H., Rizzi G., Stamatakis A.M., Ung R.L., Stuber G.D. The inhibitory circuit architecture of the lateral hypothalamus orchestrates feeding. Science 2013, 341:1517-1521.
    • (2013) Science , vol.341 , pp. 1517-1521
    • Jennings, J.H.1    Rizzi, G.2    Stamatakis, A.M.3    Ung, R.L.4    Stuber, G.D.5
  • 22
    • 28744446111 scopus 로고    scopus 로고
    • Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons
    • Karpova A.Y., Tervo D.G., Gray N.W., Svoboda K. Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons. Neuron 2005, 48:727-735.
    • (2005) Neuron , vol.48 , pp. 727-735
    • Karpova, A.Y.1    Tervo, D.G.2    Gray, N.W.3    Svoboda, K.4
  • 23
    • 84856418376 scopus 로고    scopus 로고
    • MGRASP enables mapping mammalian synaptic connectivity with light microscopy
    • Kim J., Zhao T., Petralia R.S., Yu Y., Peng H., Myers E., Magee J.C. mGRASP enables mapping mammalian synaptic connectivity with light microscopy. Nat. Methods 2012, 9:96-102.
    • (2012) Nat. Methods , vol.9 , pp. 96-102
    • Kim, J.1    Zhao, T.2    Petralia, R.S.3    Yu, Y.4    Peng, H.5    Myers, E.6    Magee, J.C.7
  • 24
    • 0023890753 scopus 로고
    • PVN-hindbrain pathway involved inthe hypothalamic hyperphagia-obesity syndrome
    • Kirchgessner A.L., Sclafani A. PVN-hindbrain pathway involved inthe hypothalamic hyperphagia-obesity syndrome. Physiol. Behav. 1988, 42:517-528.
    • (1988) Physiol. Behav. , vol.42 , pp. 517-528
    • Kirchgessner, A.L.1    Sclafani, A.2
  • 25
    • 0038545867 scopus 로고    scopus 로고
    • Targeted expression of temperature-sensitive dynamin to study neural mechanisms of complex behavior in Drosophila
    • Kitamoto T. Targeted expression of temperature-sensitive dynamin to study neural mechanisms of complex behavior in Drosophila. J.Neurogenet. 2002, 16:205-228.
    • (2002) J.Neurogenet. , vol.16 , pp. 205-228
    • Kitamoto, T.1
  • 26
    • 0023835486 scopus 로고
    • Comparative studies of the ingestive behaviors produced by microinjections of muscimol into the midbrain raphe nuclei of the ventral tegmental area of the rat
    • Klitenick M.A., Wirtshafter D. Comparative studies of the ingestive behaviors produced by microinjections of muscimol into the midbrain raphe nuclei of the ventral tegmental area of the rat. Life Sci. 1988, 42:775-782.
    • (1988) Life Sci. , vol.42 , pp. 775-782
    • Klitenick, M.A.1    Wirtshafter, D.2
  • 28
    • 0023192109 scopus 로고
    • Bombesin-induced anorexia: sites of action in the rat brain
    • Kyrkouli S.E., Stanley B.G., Leibowitz S.F. Bombesin-induced anorexia: sites of action in the rat brain. Peptides 1987, 8:237-241.
    • (1987) Peptides , vol.8 , pp. 237-241
    • Kyrkouli, S.E.1    Stanley, B.G.2    Leibowitz, S.F.3
  • 29
    • 79953695368 scopus 로고    scopus 로고
    • A role for myosin VI in the localization of axonal proteins
    • Lewis T.L., Mao T., Arnold D.B. A role for myosin VI in the localization of axonal proteins. PLoS Biol. 2011, 9:e1001021.
    • (2011) PLoS Biol. , vol.9
    • Lewis, T.L.1    Mao, T.2    Arnold, D.B.3
  • 30
    • 84880688619 scopus 로고    scopus 로고
    • Optogenetic inhibition of synaptic release with chromophore-assisted light inactivation (CALI)
    • Lin J.Y., Sann S.B., Zhou K., Nabavi S., Proulx C.D., Malinow R., Jin Y., Tsien R.Y. Optogenetic inhibition of synaptic release with chromophore-assisted light inactivation (CALI). Neuron 2013, 79:241-253.
    • (2013) Neuron , vol.79 , pp. 241-253
    • Lin, J.Y.1    Sann, S.B.2    Zhou, K.3    Nabavi, S.4    Proulx, C.D.5    Malinow, R.6    Jin, Y.7    Tsien, R.Y.8
  • 32
    • 80052436339 scopus 로고    scopus 로고
    • Chemical and genetic engineering of selective ion channel-ligand interactions
    • Magnus C.J., Lee P.H., Atasoy D., Su H.H., Looger L.L., Sternson S.M. Chemical and genetic engineering of selective ion channel-ligand interactions. Science 2011, 333:1292-1296.
    • (2011) Science , vol.333 , pp. 1292-1296
    • Magnus, C.J.1    Lee, P.H.2    Atasoy, D.3    Su, H.H.4    Looger, L.L.5    Sternson, S.M.6
  • 34
    • 0021164310 scopus 로고
    • Clonidine-induced feeding: analysis of central sites of action and fiber projections mediating this response
    • McCabe J.T., DeBellis M., Leibowitz S.F. Clonidine-induced feeding: analysis of central sites of action and fiber projections mediating this response. Brain Res. 1984, 309:85-104.
    • (1984) Brain Res. , vol.309 , pp. 85-104
    • McCabe, J.T.1    DeBellis, M.2    Leibowitz, S.F.3
  • 35
    • 34247548430 scopus 로고    scopus 로고
    • Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections
    • Petreanu L., Huber D., Sobczyk A., Svoboda K. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat. Neurosci. 2007, 10:663-668.
    • (2007) Nat. Neurosci. , vol.10 , pp. 663-668
    • Petreanu, L.1    Huber, D.2    Sobczyk, A.3    Svoboda, K.4
  • 36
    • 33645227423 scopus 로고    scopus 로고
    • G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties
    • Photowala H., Blackmer T., Schwartz E., Hamm H.E., Alford S. G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties. Proc. Natl. Acad. Sci. USA 2006, 103:4281-4286.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4281-4286
    • Photowala, H.1    Blackmer, T.2    Schwartz, E.3    Hamm, H.E.4    Alford, S.5
  • 37
    • 0031841088 scopus 로고    scopus 로고
    • Differential presynaptic and postsynaptic expression of m1-m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse
    • Rouse S.T., Gilmor M.L., Levey A.I. Differential presynaptic and postsynaptic expression of m1-m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse. Neuroscience 1998, 86:221-232.
    • (1998) Neuroscience , vol.86 , pp. 221-232
    • Rouse, S.T.1    Gilmor, M.L.2    Levey, A.I.3
  • 38
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH -> arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson S.M., Shepherd G.M., Friedman J.M. Topographic mapping of VMH -> arcuate nucleus microcircuits and their reorganization by fasting. Nat. Neurosci. 2005, 8:1356-1363.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 40
    • 0032079846 scopus 로고    scopus 로고
    • G-Protein-coupled modulation of presynaptic calcium currents and transmitter release by a GABAB receptor
    • Takahashi T., Kajikawa Y., Tsujimoto T. G-Protein-coupled modulation of presynaptic calcium currents and transmitter release by a GABAB receptor. J.Neurosci. 1998, 18:3138-3146.
    • (1998) J.Neurosci. , vol.18 , pp. 3138-3146
    • Takahashi, T.1    Kajikawa, Y.2    Tsujimoto, T.3
  • 41
    • 50249120768 scopus 로고    scopus 로고
    • Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    • Tong Q., Ye C.P., Jones J.E., Elmquist J.K., Lowell B.B. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat. Neurosci. 2008, 11:998-1000.
    • (2008) Nat. Neurosci. , vol.11 , pp. 998-1000
    • Tong, Q.1    Ye, C.P.2    Jones, J.E.3    Elmquist, J.K.4    Lowell, B.B.5
  • 43
    • 0022341109 scopus 로고
    • Efferent projections from the paraventricular nucleus mediating alpha 2-noradrenergic feeding
    • Weiss G.F., Leibowitz S.F. Efferent projections from the paraventricular nucleus mediating alpha 2-noradrenergic feeding. Brain Res. 1985, 347:225-238.
    • (1985) Brain Res. , vol.347 , pp. 225-238
    • Weiss, G.F.1    Leibowitz, S.F.2
  • 44
    • 84859215897 scopus 로고    scopus 로고
    • Deciphering a neuronal circuit that mediates appetite
    • Wu Q., Clark M.S., Palmiter R.D. Deciphering a neuronal circuit that mediates appetite. Nature 2012, 483:594-597.
    • (2012) Nature , vol.483 , pp. 594-597
    • Wu, Q.1    Clark, M.S.2    Palmiter, R.D.3
  • 45
    • 84889659070 scopus 로고    scopus 로고
    • Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation
    • Xu Y., Wu Z., Sun H., Zhu Y., Kim E.R., Lowell B.B., Arenkiel B.R., Xu Y., Tong Q. Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation. Cell Metab. 2013, 18:860-870.
    • (2013) Cell Metab. , vol.18 , pp. 860-870
    • Xu, Y.1    Wu, Z.2    Sun, H.3    Zhu, Y.4    Kim, E.R.5    Lowell, B.B.6    Arenkiel, B.R.7    Xu, Y.8    Tong, Q.9
  • 46
    • 0042634348 scopus 로고    scopus 로고
    • Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells invivo by genetically manipulated expression of tetanus neurotoxin light chain
    • Yamamoto M., Wada N., Kitabatake Y., Watanabe D., Anzai M., Yokoyama M., Teranishi Y., Nakanishi S. Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells invivo by genetically manipulated expression of tetanus neurotoxin light chain. J.Neurosci. 2003, 23:6759-6767.
    • (2003) J.Neurosci. , vol.23 , pp. 6759-6767
    • Yamamoto, M.1    Wada, N.2    Kitabatake, Y.3    Watanabe, D.4    Anzai, M.5    Yokoyama, M.6    Teranishi, Y.7    Nakanishi, S.8
  • 47
    • 0036522982 scopus 로고    scopus 로고
    • Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice
    • Zhang W., Basile A.S., Gomeza J., Volpicelli L.A., Levey A.I., Wess J. Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice. J.Neurosci. 2002, 22:1709-1717.
    • (2002) J.Neurosci. , vol.22 , pp. 1709-1717
    • Zhang, W.1    Basile, A.S.2    Gomeza, J.3    Volpicelli, L.A.4    Levey, A.I.5    Wess, J.6
  • 48
    • 0029348838 scopus 로고
    • Descending projections from the paraventricular hypothalamic nucleus to the spinal cord: anterograde tracing study in the rat
    • Zheng J.Q., Seki M., Hayakawa T., Ito H., Zyo K. Descending projections from the paraventricular hypothalamic nucleus to the spinal cord: anterograde tracing study in the rat. Okajimas Folia Anat. Jpn. 1995, 72:119-135.
    • (1995) Okajimas Folia Anat. Jpn. , vol.72 , pp. 119-135
    • Zheng, J.Q.1    Seki, M.2    Hayakawa, T.3    Ito, H.4    Zyo, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.