메뉴 건너뛰기




Volumn 23, Issue 17, 2003, Pages 6759-6767

Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells in vivo by genetically manipulated expression of tetanus neurotoxin light chain

Author keywords

Cerebellum; GABAA receptor; Glutamatergic transmission; Granule cell; Tetanus neurotoxin; Tetracycline inducible system; Transgenic mouse; VAMP2

Indexed keywords

BETA TUBULIN; CELLUBREVIN; DOXYCYCLINE; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN LIGHT CHAIN; NEUROTOXIN; RECEPTOR SUBUNIT; SYNAPTOBREVIN; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; SYNTAXIN; TETANUS TOXIN; TETRACYCLINE;

EID: 0042634348     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-17-06759.2003     Document Type: Article
Times cited : (124)

References (64)
  • 2
    • 0028048223 scopus 로고
    • Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats
    • Akazawa C, Shigemoto R, Bessho Y, Nakanishi S, Mizuno N (1994) Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J Comp Neurol 347:150-160.
    • (1994) J Comp Neurol , vol.347 , pp. 150-160
    • Akazawa, C.1    Shigemoto, R.2    Bessho, Y.3    Nakanishi, S.4    Mizuno, N.5
  • 3
    • 0025007115 scopus 로고
    • Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2
    • Archer BT, Özçelik T, Jahn R, Francke U, Südhof TC (1990) Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2. J Biol Chem 265:17267-17273.
    • (1990) J Biol Chem , vol.265 , pp. 17267-17273
    • Archer, B.T.1    Özçelik, T.2    Jahn, R.3    Francke, U.4    Südhof, T.C.5
  • 4
    • 0030875173 scopus 로고    scopus 로고
    • Directing gene expression to cerebellar granule cells using γ-aminobutyric acid type A receptor α6 subunit transgenes
    • Bahn S, Jones A, Wisden W (1997) Directing gene expression to cerebellar granule cells using γ-aminobutyric acid type A receptor α6 subunit transgenes. Proc Natl Acad Sci USA 94:9417-9421.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9417-9421
    • Bahn, S.1    Jones, A.2    Wisden, W.3
  • 5
    • 0024366008 scopus 로고
    • Synaptobrevin: An integral membrane protein of 18,000 Daltons present in small synaptic vesicles of rat brain
    • Baumert M, Maycox PR, Navone F, De Camilli P, Jahn R (1989) Synaptobrevin: an integral membrane protein of 18,000 Daltons present in small synaptic vesicles of rat brain. EMBO J 8:379-384.
    • (1989) EMBO J , vol.8 , pp. 379-384
    • Baumert, M.1    Maycox, P.R.2    Navone, F.3    De Camilli, P.4    Jahn, R.5
  • 6
    • 0025358573 scopus 로고
    • Calbindin D-28K and parvalbumin in the rat nervous system
    • Celio MR (1990) Calbindin D-28K and parvalbumin in the rat nervous system. Neuroscience 35:375-475.
    • (1990) Neuroscience , vol.35 , pp. 375-475
    • Celio, M.R.1
  • 10
    • 0032031999 scopus 로고    scopus 로고
    • Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex
    • De Zeeuw CI, Hansel C, Bian F, Koekkoek SKE, van Alphen AM, Linden DJ, Oberdick J (1998) Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron 20:495-508.
    • (1998) Neuron , vol.20 , pp. 495-508
    • De Zeeuw, C.I.1    Hansel, C.2    Bian, F.3    Koekkoek, S.K.E.4    Van Alphen, A.M.5    Linden, D.J.6    Oberdick, J.7
  • 11
    • 0035942734 scopus 로고    scopus 로고
    • Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory
    • Dubnau J, Grady L, Kitamoto T, Tully T (2001) Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory. Nature 411:476-480.
    • (2001) Nature , vol.411 , pp. 476-480
    • Dubnau, J.1    Grady, L.2    Kitamoto, T.3    Tully, T.4
  • 12
    • 0027201146 scopus 로고
    • Tetanus toxin light chain expression in Sertoli cells of transgenic mice causes alterations of the actin cytoskeleton and disrupts spermatogenesis
    • Eisel U, Reynolds K, Riddick M, Zimmer A, Niemann H, Zimmer A (1993) Tetanus toxin light chain expression in Sertoli cells of transgenic mice causes alterations of the actin cytoskeleton and disrupts spermatogenesis. EMBO J 12:3365-3372.
    • (1993) EMBO J , vol.12 , pp. 3365-3372
    • Eisel, U.1    Reynolds, K.2    Riddick, M.3    Zimmer, A.4    Niemann, H.5    Zimmer, A.6
  • 13
    • 0024308501 scopus 로고
    • Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous system
    • Elferink LA, Trimble WS, Scheller RH (1989) Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous system. J Biol Chem 264:11061-11064.
    • (1989) J Biol Chem , vol.264 , pp. 11061-11064
    • Elferink, L.A.1    Trimble, W.S.2    Scheller, R.H.3
  • 14
    • 0028291894 scopus 로고
    • Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferring receptor-containing vesicles in CHO cells
    • Galli T, Chilcote T, Mundigl O, Binz T, Niemann H, De Camilli P (1994) Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferring receptor-containing vesicles in CHO cells. J Cell Biol 125:1015-1024.
    • (1994) J Cell Biol , vol.125 , pp. 1015-1024
    • Galli, T.1    Chilcote, T.2    Mundigl, O.3    Binz, T.4    Niemann, H.5    De Camilli, P.6
  • 15
    • 0033698229 scopus 로고    scopus 로고
    • Genetic ablation and restoration of the olfactory topographic map
    • Gogos JA, Osborne J, Nemes A, Mendelsohn M, Axel R (2000) Genetic ablation and restoration of the olfactory topographic map. Cell 103:609-620.
    • (2000) Cell , vol.103 , pp. 609-620
    • Gogos, J.A.1    Osborne, J.2    Nemes, A.3    Mendelsohn, M.4    Axel, R.5
  • 19
    • 0024520759 scopus 로고
    • Long-term depression
    • Ito M (1989) Long-term depression. Annu Rev Neurosci 12:85-102.
    • (1989) Annu Rev Neurosci , vol.12 , pp. 85-102
    • Ito, M.1
  • 20
    • 0031830694 scopus 로고    scopus 로고
    • Cerebellar learning in the vestibulo-ocular reflex
    • Ito M (1998) Cerebellar learning in the vestibulo-ocular reflex. Trends Cogn Sci 2:313-321.
    • (1998) Trends Cogn Sci , vol.2 , pp. 313-321
    • Ito, M.1
  • 21
    • 0020005065 scopus 로고
    • Climbing fibre induced depression of both mossy fibre responsiveness and glutamate sensitivity of cerebellar Purkinje cells
    • Ito M, Sakurai M, Tongroach P (1982) Climbing fibre induced depression of both mossy fibre responsiveness and glutamate sensitivity of cerebellar Purkinje cells. J Physiol (Lond) 324:113-134.
    • (1982) J Physiol (Lond) , vol.324 , pp. 113-134
    • Ito, M.1    Sakurai, M.2    Tongroach, P.3
  • 22
    • 0025253838 scopus 로고
    • The novel mechanism of initiation of picornavirus RNA translation
    • Jackson RJ, Howell MT, Kaminski A (1990) The novel mechanism of initiation of picornavirus RNA translation. Trends Biochem Sci 15:477-483.
    • (1990) Trends Biochem Sci , vol.15 , pp. 477-483
    • Jackson, R.J.1    Howell, M.T.2    Kaminski, A.3
  • 23
    • 0029848478 scopus 로고    scopus 로고
    • Characterization of a cerebellar granule cell-specific gene encoding the γ-aminobutyric acid type A receptor α6 subunit
    • Jones A, Bahn S, Grant AL, Köhler M, Wisden W (1996) Characterization of a cerebellar granule cell-specific gene encoding the γ-aminobutyric acid type A receptor α6 subunit. J Neurochem 67:907-916.
    • (1996) J Neurochem , vol.67 , pp. 907-916
    • Jones, A.1    Bahn, S.2    Grant, A.L.3    Köhler, M.4    Wisden, W.5
  • 24
    • 0029812141 scopus 로고    scopus 로고
    • Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit
    • Kadotani H, Hirano T, Masugi M, Nakamura K, Nakao K, Katsuki M, Nakanishi S (1996) Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit. J Neurosci 16:7859-7867.
    • (1996) J Neurosci , vol.16 , pp. 7859-7867
    • Kadotani, H.1    Hirano, T.2    Masugi, M.3    Nakamura, K.4    Nakao, K.5    Katsuki, M.6    Nakanishi, S.7
  • 26
    • 0033897705 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthesis and gene knockout of neuronal nitric oxide synthase impaired adaptation of mouse optokinetic response eye movements
    • Katoh A, Kitazawa H, Itohara S, Nagao S (2000) Inhibition of nitric oxide synthesis and gene knockout of neuronal nitric oxide synthase impaired adaptation of mouse optokinetic response eye movements. Learn Mem 7:220-226.
    • (2000) Learn Mem , vol.7 , pp. 220-226
    • Katoh, A.1    Kitazawa, H.2    Itohara, S.3    Nagao, S.4
  • 29
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak M (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 30
    • 0026612362 scopus 로고
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci 12:1063-1076.
    • (1992) J Neurosci , vol.12 , pp. 1063-1076
    • Laurie, D.J.1    Seeburg, P.H.2    Wisden, W.3
  • 31
    • 0032567339 scopus 로고    scopus 로고
    • Generation of destabilized green fluorescent protein as a transcription reporter
    • Li X, Zhao X, Fang Y, Jiang X, Duong T, Fan C, Huang C-C, Kain SR (1998) Generation of destabilized green fluorescent protein as a transcription reporter. J Biol Chem 273:34970-34975.
    • (1998) J Biol Chem , vol.273 , pp. 34970-34975
    • Li, X.1    Zhao, X.2    Fang, Y.3    Jiang, X.4    Duong, T.5    Fan, C.6    Huang, C.-C.7    Kain, S.R.8
  • 32
    • 0028208421 scopus 로고
    • Long-term synaptic depression in the mammalian brain
    • Linden DJ (1994) Long-term synaptic depression in the mammalian brain. Neuron 12:457-472.
    • (1994) Neuron , vol.12 , pp. 457-472
    • Linden, D.J.1
  • 34
    • 0023716463 scopus 로고
    • The neural basis for learning of simple motor skills
    • Lisberger SG (1988) The neural basis for learning of simple motor skills. Science 242:728-735.
    • (1988) Science , vol.242 , pp. 728-735
    • Lisberger, S.G.1
  • 35
    • 0032214487 scopus 로고    scopus 로고
    • Mechanism of action of rab3A in mossy fiber LTP
    • Lonart G, Janz R, Johnson KM, Südhof TC (1998) Mechanism of action of rab3A in mossy fiber LTP. Neuron 21:1141-1150.
    • (1998) Neuron , vol.21 , pp. 1141-1150
    • Lonart, G.1    Janz, R.2    Johnson, K.M.3    Südhof, T.C.4
  • 37
    • 0035903017 scopus 로고    scopus 로고
    • The role of Drosophila mushroom body signaling in olfactory memory
    • McGuire SE, Le PT, Davis RL (2001) The role of Drosophila mushroom body signaling in olfactory memory. Science 293:1330-1333.
    • (2001) Science , vol.293 , pp. 1330-1333
    • McGuire, S.E.1    Le, P.T.2    Davis, R.L.3
  • 38
    • 0027265710 scopus 로고
    • Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
    • McMahon HT, Ushkaryov YA, Edelmann L, Link E, Binz T, Niemann H, Jahn R, Südhof TC (1993) Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature 364:346-349.
    • (1993) Nature , vol.364 , pp. 346-349
    • McMahon, H.T.1    Ushkaryov, Y.A.2    Edelmann, L.3    Link, E.4    Binz, T.5    Niemann, H.6    Jahn, R.7    Südhof, T.C.8
  • 39
    • 0035862965 scopus 로고    scopus 로고
    • Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor ε1 subunit
    • Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T (2001) Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor ε1 subunit. J Neurosci 21:750-757.
    • (2001) J Neurosci , vol.21 , pp. 750-757
    • Miyamoto, Y.1    Yamada, K.2    Noda, Y.3    Mori, H.4    Mishina, M.5    Nabeshima, T.6
  • 40
    • 0024356962 scopus 로고
    • Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuroneuronal synapses, and its internalization is mediated by heavy chain
    • Mochida S, Poulain B, Weller U, Habermann E, Tauc L (1989) Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuroneuronal synapses, and its internalization is mediated by heavy chain. FEBS Lett 253:47-51.
    • (1989) FEBS Lett , vol.253 , pp. 47-51
    • Mochida, S.1    Poulain, B.2    Weller, U.3    Habermann, E.4    Tauc, L.5
  • 41
    • 0023755390 scopus 로고
    • Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat
    • Napper RMA, Harvey RJ (1988) Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. J Comp Neurol 274:168-177.
    • (1988) J Comp Neurol , vol.274 , pp. 168-177
    • Napper, R.M.A.1    Harvey, R.J.2
  • 42
    • 0027176320 scopus 로고
    • Targeted ablation of diverse cell classes in the nervous system in vivo
    • Nirenberg S, Cepko C (1993) Targeted ablation of diverse cell classes in the nervous system in vivo. J Neurosci 13:3238-3251.
    • (1993) J Neurosci , vol.13 , pp. 3238-3251
    • Nirenberg, S.1    Cepko, C.2
  • 43
    • 0028088017 scopus 로고
    • Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex
    • Ohishi H, Ogawa-Meguro R, Shigemoto R, Kaneko T, Nakanishi S, Mizuno N (1994) Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron 13:55-66.
    • (1994) Neuron , vol.13 , pp. 55-66
    • Ohishi, H.1    Ogawa-Meguro, R.2    Shigemoto, R.3    Kaneko, T.4    Nakanishi, S.5    Mizuno, N.6
  • 44
    • 0028966170 scopus 로고
    • Expression and complex formation of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptors in clonal rat endocrine cells
    • Oho C, Seino S, Takahashi M (1995) Expression and complex formation of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptors in clonal rat endocrine cells. Neurosci Lett 186:208-210.
    • (1995) Neurosci Lett , vol.186 , pp. 208-210
    • Oho, C.1    Seino, S.2    Takahashi, M.3
  • 50
    • 0027517462 scopus 로고
    • A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
    • Söllner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE (1993b) A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75:409-418.
    • (1993) Cell , vol.75 , pp. 409-418
    • Söllner, T.1    Bennett, M.K.2    Whiteheart, S.W.3    Scheller, R.H.4    Rothman, J.E.5
  • 51
    • 0032416664 scopus 로고    scopus 로고
    • Using genetic mutations to study the neural basis of behavior
    • Steele PM, Medina JF, Notes WL, Mauk MD (1998) Using genetic mutations to study the neural basis of behavior. Cell 95:879-882.
    • (1998) Cell , vol.95 , pp. 879-882
    • Steele, P.M.1    Medina, J.F.2    Notes, W.L.3    Mauk, M.D.4
  • 52
    • 0029026392 scopus 로고
    • The synaptic vesicle cycle: A cascade of protein-protein interactions
    • Südhof TC (1995) The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375:645-653.
    • (1995) Nature , vol.375 , pp. 645-653
    • Südhof, T.C.1
  • 53
    • 0028815501 scopus 로고
    • Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects
    • Sweeney ST, Broadie K, Keane J, Niemann H, O'Kane CJ (1995) Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects. Neuron 14:341-351.
    • (1995) Neuron , vol.14 , pp. 341-351
    • Sweeney, S.T.1    Broadie, K.2    Keane, J.3    Niemann, H.4    O'Kane, C.J.5
  • 54
    • 0028231217 scopus 로고
    • Organization of memory traces in the mammalian brain
    • Thompson RF, Krupa DJ (1994) Organization of memory traces in the mammalian brain. Annu Rev Neurosci 17:519-549.
    • (1994) Annu Rev Neurosci , vol.17 , pp. 519-549
    • Thompson, R.F.1    Krupa, D.J.2
  • 56
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
    • Urlinger S, Baron U, Thellmann M, Hasan MT, Bujard H, Hillen W (2000) Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 97:7963-7968.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3    Hasan, M.T.4    Bujard, H.5    Hillen, W.6
  • 57
    • 0028181651 scopus 로고
    • A/benzodiazepine receptor α6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: Expression in developing and mutant mice
    • A/benzodiazepine receptor α6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice. J Comp Neurol 339:341-352.
    • (1994) J Comp Neurol , vol.339 , pp. 341-352
    • Varecka, L.1    Wu, C.-H.2    Rotter, A.3    Frostholm, A.4
  • 59
    • 0035846595 scopus 로고    scopus 로고
    • Molecular genetic approaches to the targeted suppression of neuronal activity
    • White BH, Osterwalder TP, Keshishian H (2001) Molecular genetic approaches to the targeted suppression of neuronal activity. Curr Biol 11:R1041-R1053.
    • (2001) Curr Biol , vol.11
    • White, B.H.1    Osterwalder, T.P.2    Keshishian, H.3
  • 64
    • 0000596508 scopus 로고
    • On-line amperometric assay of glucose, L-glutamate, and acetylcholine using microdialysis probes and immobilized enzyme reactors
    • Yao T, Suzuki S, Nishino H, Nakahara T (1995) On-line amperometric assay of glucose, L-glutamate, and acetylcholine using microdialysis probes and immobilized enzyme reactors. Electroanalysis 7:1114-1117.
    • (1995) Electroanalysis , vol.7 , pp. 1114-1117
    • Yao, T.1    Suzuki, S.2    Nishino, H.3    Nakahara, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.