PSD-93 deletion inhibits Fyn-mediated phosphorylation of NR2B and protects against focal cerebral ischemia

Neurobiology of Disease

Volumn 68, Issue , 2014, Pages 104-111

  Zhang, Meijuan ^a,b,c   Li, Qingjie ^a   Chen, Ling ^b   Li, Jie ^a   Zhang, Xin ^a,b,c   Chen, Xiang ^a   Zhang, Qingxiu ^a   Shao, Yuan ^a   Xu, Yun ^a,b,c  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b NANJING UNIVERSITY   (China)

^c Diagnosis and Therapy Center of Stroke   (China)

Author keywords

Fyn; Ischemic stroke; NMDAR; PSD 93; Tyrosine phosphorylation

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN KINASE FYN; TYROSINE; 2-AMINO-5-PHOSPHOPENTANOIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; DLGH4 PROTEIN, MOUSE; FYN PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR; VALINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; GENE; GENE DELETION; GENE DISRUPTION; IN VITRO STUDY; LONG TERM POTENTIATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PSD 93 GENE; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; CELL SURVIVAL; COMPLICATION; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; EXCITATORY POSTSYNAPTIC POTENTIAL; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; KNOCKOUT MOUSE; METABOLISM; NERVOUS SYSTEM DISEASES; TIME;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE EXPRESSION REGULATION; GUANYLATE KINASE; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVOUS SYSTEM DISEASES; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS; VALINE;

EID: 84901009937     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.04.010     Document Type: Article

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