Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons

Experimental Neurology

Volumn 189, Issue 1, 2004, Pages 16-24

  Xu, Yun ^a,b   Zhang, Bosheng ^a   Hua, Zichun ^c   Johns, Roger A ^a   Bredt, David S ^d   Tao, Yuan Xiang ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^c NANJING UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell culture; N methyl D aspartate receptor; Neurotoxicity; Platelet activating factor; PSD 93

Indexed keywords

CYCLIC GMP; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; PROTEIN; PSD 93 PROTEIN; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BRAIN CELL; BRAIN CORTEX; CONTROLLED STUDY; EMBRYO; GENE DISRUPTION; MOUSE; NERVE CELL CULTURE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CELL COUNT; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC GMP; DITERPENES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; FLUORESCENT ANTIBODY TECHNIQUE; GINKGOLIDES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTONES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PLATELET ACTIVATING FACTOR; PRECIPITIN TESTS; PROPIDIUM; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 3543065264     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.05.013     Document Type: Article

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