Incremental replacement of saturated fats by n-3 fatty acids in high-fat, high-cholesterol diets reduces elevated plasma lipid levels and arterial lipoprotein lipase, macrophages and atherosclerosis in LDLR-/- mice

Atherosclerosis

Volumn 234, Issue 2, 2014, Pages 401-409

  Chang, Chuchun L ^a   Torrejon, Claudia ^a,b   Jung, Un Ju ^a   Graf, Kristin ^b   Deckelbaum, Richard J ^a  

^a Institute of Human Nutrition College of Physicians and Surgeons Columbia University ^*  (United States)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Atherosclerosis; Inflammation; LDLR ; Lipoprotein lipase; N 3 fatty acids

Indexed keywords

ARACHIDONIC ACID; CD68 ANTIGEN; CHOLESTEROL; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LAURIC ACID; LINOLEIC ACID; LIPID; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYRISTIC ACID; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SATURATED FATTY ACID; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; AUTACOID; CD68 PROTEIN, MOUSE; CHOLESTEROL INTAKE; DIFFERENTIATION ANTIGEN; FISH OIL; INTERLEUKIN-6, MOUSE; LEUKOCYTE ANTIGEN; MENHADEN OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTERY WALL; ARTICLE; ATHEROGENESIS; BODY WEIGHT; CARDIOVASCULAR EFFECT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; LIPID COMPOSITION; LIPID DIET; LIPID STORAGE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; AORTA; AORTIC DISEASES; ATHEROSCLEROSIS; BLOOD; CHOLESTEROL INTAKE; DEFICIENCY; DIET THERAPY; DISEASE MODEL; DOWN REGULATION; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; TIME;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; AORTA; AORTIC DISEASES; ATHEROSCLEROSIS; BODY WEIGHT; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FISH OILS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIPIDS; LIPOPROTEIN LIPASE; MACROPHAGES; MALE; MICE, KNOCKOUT; RECEPTORS, LDL; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84900854744     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.03.022     Document Type: Article

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