An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

Genes and Development

Volumn 28, Issue 10, 2014, Pages 1068-1084

  Adler, Adam S ^a   McCleland, Mark L ^a   Yee, Sharon ^a   Yaylaoglu, Murat ^a   Hussain, Sofia ^a   Cosino, Ely ^a   Quinones, Gabriel ^a   Modrusan, Zora ^a   Seshagiri, Somasekar ^a   Torres, Eric ^a   Chopra, Vivek S ^a   Haley, Benjamin ^a   Zhang, Zemin ^a   Blackwood, Elizabeth M ^a   Singh, Mallika ^a   Junttila, Melissa ^a   Stephan, Jean Philippe ^a   Liu, Jinfeng ^a   Pau, Gregoire ^a   Fearon, Eric R ^b   Jiang, Zhaoshi ^a   Firestein, Ron ^a   more..

^a GENENTECH INC   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Colon cancer; PRPF6; RNAi; Spliceosome; Tri snRNP

Indexed keywords

MICRORNA; PRPF6 PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CANCER CELL; CANCER CELL LINE; CANCER GROWTH; CELL COUNT; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; COPY NUMBER VARIATION; EXON; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENOMICS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOSS OF FUNCTION MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RNA SPLICING; SPLICEOSOME;

COLON CANCER; PRPF6; RNAI; SPLICEOSOME; TRI-SNRNP;

ALTERNATIVE SPLICING; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; HUMANS; PROTEIN ISOFORMS; RNA-BINDING PROTEINS; SPLICEOSOMES; TRANSCRIPTION FACTORS;

EID: 84900804430     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.237206.113     Document Type: Article

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