Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells

Oncogene

Volumn 30, Issue 39, 2011, Pages 4075-4086

  Xing, F ^a   Okuda, H ^a   Watabe, M ^a   Kobayashi, A ^a   Pai, S K ^a   Liu, W ^a   Pandey, P R ^a   Fukuda, K ^a   Hirota, S ^b   Sugai, T ^b   Wakabayshi, G ^b   Koeda, K ^b   Kashiwaba, M ^b   Suzuki, K ^b   Chiba, T ^b   Endo, M ^b   Mo, Y Y ^a   Watabe, K ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

breast cancer; cancer stem like cells; hypoxia; Jagged2; Notch

Indexed keywords

GAMMA SECRETASE INHIBITOR; JAGGED2; NOTCH RECEPTOR; PROTEIN KINASE B; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; BONE CELL; BONE MARROW CELL; BONE METASTASIS; BREAST CANCER; CANCER INVASION; CANCER PATIENT; CANCER STEM CELL; CANCER SURVIVAL; CELL RENEWAL; CELL SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL NICHE; STROMA CELL; TUMOR GROWTH; TUMOR PROMOTION; UPREGULATION;

EID: 85027941540     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.122     Document Type: Article

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