메뉴 건너뛰기




Volumn 7, Issue 325, 2014, Pages

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LONG UNTRANSLATED RNA; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTOME; ATM PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

EID: 84900552326     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005032     Document Type: Review
Times cited : (55)

References (88)
  • 1
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • T. Lindahl, Instability and decay of the primary structure of DNA. Nature 362, 709-715 (1993).
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 2
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • A. Ciccia, S. J. Elledge, The DNA damage response: Making it safe to play with knives. Mol. Cell 40, 179-204 (2010).
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 3
    • 84865620494 scopus 로고    scopus 로고
    • Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
    • L. H. Thompson, Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography. Mutat. Res. 751, 158-246 (2012).
    • (2012) Mutat. Res. , vol.751 , pp. 158-246
    • Thompson, L.H.1
  • 5
    • 84870738828 scopus 로고    scopus 로고
    • Diseases associated with defective responses to DNA damage
    • M. O'Driscoll, Diseases associated with defective responses to DNA damage. Cold Spring Harb. Perspect. Biol. 4, a012773 (2012).
    • (2012) Cold Spring Harb. Perspect. Biol. , vol.4
    • O'Driscoll, M.1
  • 7
    • 84873635293 scopus 로고    scopus 로고
    • Genome instability and aging
    • J. Vijg, Y. Suh, Genome instability and aging. Annu. Rev. Physiol. 75, 645-668 (2013).
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 645-668
    • Vijg, J.1    Suh, Y.2
  • 9
    • 84859864552 scopus 로고    scopus 로고
    • Targeting the DNA damage response in oncology: Past, present and future perspectives
    • B. Basu, T. A. Yap, L. R. Molife, J. S. de Bono, Targeting the DNA damage response in oncology: Past, present and future perspectives. Curr. Opin. Oncol. 24, 316-324 (2012).
    • (2012) Curr. Opin. Oncol. , vol.24 , pp. 316-324
    • Basu, B.1    Yap, T.A.2    Molife, L.R.3    De Bono, J.S.4
  • 10
    • 84894353718 scopus 로고    scopus 로고
    • DNA damage response: Three levels of DNA repair regulation
    • B. M. Sirbu, D. Cortez, DNA damage response: Three levels of DNA repair regulation. Cold Spring Harb. Perspect. Biol. 5, a012724 (2013).
    • (2013) Cold Spring Harb. Perspect. Biol. , vol.5
    • Sirbu, B.M.1    Cortez, D.2
  • 11
    • 84877824046 scopus 로고    scopus 로고
    • Programmed induction of DNA double strand breaks during meiosis: Setting up communication between DNA and the chromosome structure
    • V. Borde, B. de Massy, Programmed induction of DNA double strand breaks during meiosis: Setting up communication between DNA and the chromosome structure. Curr. Opin. Genet. Dev. 23, 147-155 (2013).
    • (2013) Curr. Opin. Genet. Dev. , vol.23 , pp. 147-155
    • Borde, V.1    De Massy, B.2
  • 12
    • 84873320525 scopus 로고    scopus 로고
    • Mechanisms of programmed DNA lesions and genomic instability in the immune system
    • F. W. Alt, Y. Zhang, F. L. Meng, C. Guo, B. Schwer, Mechanisms of programmed DNA lesions and genomic instability in the immune system. Cell 152, 417-429 (2013).
    • (2013) Cell , vol.152 , pp. 417-429
    • Alt, F.W.1    Zhang, Y.2    Meng, F.L.3    Guo, C.4    Schwer, B.5
  • 13
    • 84875423827 scopus 로고    scopus 로고
    • The ATM protein kinase: Regulating the cellular response to genotoxic stress, and more
    • Y. Shiloh, Y. Ziv, The ATM protein kinase: Regulating the cellular response to genotoxic stress, and more. Nat. Rev. Mol. Cell Biol. 14, 197-210 (2013).
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 197-210
    • Shiloh, Y.1    Ziv, Y.2
  • 14
    • 79952235291 scopus 로고    scopus 로고
    • Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
    • S. E. Polo, S. P. Jackson, Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications. Genes Dev. 25, 409-433 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 409-433
    • Polo, S.E.1    Jackson, S.P.2
  • 16
    • 84892431829 scopus 로고    scopus 로고
    • Checkpoint kinases regulate a global network of transcription factors in response to DNA damage
    • E. J. Jaehnig, D. Kuo, H. Hombauer, T. G. Ideker, R. D. Kolodner, Checkpoint kinases regulate a global network of transcription factors in response to DNA damage. Cell Rep. 4, 174-188 (2013).
    • (2013) Cell Rep. , vol.4 , pp. 174-188
    • Jaehnig, E.J.1    Kuo, D.2    Hombauer, H.3    Ideker, T.G.4    Kolodner, R.D.5
  • 18
    • 84883559012 scopus 로고    scopus 로고
    • Unraveling DNA damage response-signaling networks through systems approaches
    • L. von Stechow, B. van de Water, E. H. Danen, Unraveling DNA damage response-signaling networks through systems approaches. Arch. Toxicol. 87, 1635-1648 (2013).
    • (2013) Arch. Toxicol. , vol.87 , pp. 1635-1648
    • Von Stechow, L.1    Van De Water, B.2    Danen, E.H.3
  • 19
    • 84876093576 scopus 로고    scopus 로고
    • DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
    • W. P. Roos, B. Kaina, DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis. Cancer Lett. 332, 237-248 (2013).
    • (2013) Cancer Lett. , vol.332 , pp. 237-248
    • Roos, W.P.1    Kaina, B.2
  • 20
    • 78751570979 scopus 로고    scopus 로고
    • RNA sequencing: Advances, challenges and opportunities
    • F. Ozsolak, P. M. Milos, RNA sequencing: Advances, challenges and opportunities. Nat. Rev. Genet. 12, 87-98 (2011).
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 87-98
    • Ozsolak, F.1    Milos, P.M.2
  • 21
    • 84869502241 scopus 로고    scopus 로고
    • ChIP-seq and beyond: New and improved methodologies to detect and characterize protein-DNA interactions
    • T. S. Furey, ChIP-seq and beyond: New and improved methodologies to detect and characterize protein-DNA interactions. Nat. Rev. Genet. 13, 840-852 (2012).
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 840-852
    • Furey, T.S.1
  • 22
    • 70349312354 scopus 로고    scopus 로고
    • ChIP-seq: Advantages and challenges of a maturing technology
    • P. J. Park, ChIP-seq: Advantages and challenges of a maturing technology. Nat. Rev. Genet. 10, 669-680 (2009).
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 669-680
    • Park, P.J.1
  • 24
    • 45549084168 scopus 로고    scopus 로고
    • p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis
    • T. Kawase, H. Ichikawa, T. Ohta, N. Nozaki, F. Tashiro, R. Ohki, Y. Taya, p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis. Oncogene 27, 3797-3810 (2008).
    • (2008) Oncogene , vol.27 , pp. 3797-3810
    • Kawase, T.1    Ichikawa, H.2    Ohta, T.3    Nozaki, N.4    Tashiro, F.5    Ohki, R.6    Taya, Y.7
  • 26
    • 33748774114 scopus 로고    scopus 로고
    • Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin
    • R. Pick, S. Badura, S. Bösser, M. Zörnig, Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin. Biochem. Biophys. Res. Commun. 349, 1329-1338 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.349 , pp. 1329-1338
    • Pick, R.1    Badura, S.2    Bösser, S.3    Zörnig, M.4
  • 28
    • 84879987789 scopus 로고    scopus 로고
    • lincRNAs: Genomics, evolution, and mechanisms
    • I. Ulitsky, D. P. Bartel, lincRNAs: Genomics, evolution, and mechanisms. Cell 154, 26-46 (2013).
    • (2013) Cell , vol.154 , pp. 26-46
    • Ulitsky, I.1    Bartel, D.P.2
  • 29
    • 84875200257 scopus 로고    scopus 로고
    • Long noncoding RNAs: Cellular address codes in development and disease
    • P. J. Batista, H. Y. Chang, Long noncoding RNAs: Cellular address codes in development and disease. Cell 152, 1298-1307 (2013).
    • (2013) Cell , vol.152 , pp. 1298-1307
    • Batista, P.J.1    Chang, H.Y.2
  • 30
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • J. L. Rinn, H. Y. Chang, Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 81, 145-166 (2012).
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 31
    • 84876093209 scopus 로고    scopus 로고
    • p53 induces transcriptional and translational programs to suppress cell proliferation and growth
    • F. Loayza-Puch, J. Drost, K. Rooijers, R. Lopes, R. Elkon, R. Agami, p53 induces transcriptional and translational programs to suppress cell proliferation and growth. Genome Biol. 14, R32 (2013).
    • (2013) Genome Biol. , vol.14
    • Loayza-Puch, F.1    Drost, J.2    Rooijers, K.3    Lopes, R.4    Elkon, R.5    Agami, R.6
  • 36
    • 84864022892 scopus 로고    scopus 로고
    • E2F7, a novel target, is upregulated by p53 and mediates DNA damage-dependent transcriptional repression
    • L. A. Carvajal, P. J. Hamard, C. Tonnessen, J. J. Manfredi, E2F7, a novel target, is upregulated by p53 and mediates DNA damage-dependent transcriptional repression. Genes Dev. 26, 1533-1545 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 1533-1545
    • Carvajal, L.A.1    Hamard, P.J.2    Tonnessen, C.3    Manfredi, J.J.4
  • 37
    • 84864011866 scopus 로고    scopus 로고
    • The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence
    • O. Aksoy, A. Chicas, T. Zeng, Z. Zhao, M. McCurrach, X. Wang, S. W. Lowe, The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence. Genes Dev. 26, 1546-1557 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 1546-1557
    • Aksoy, O.1    Chicas, A.2    Zeng, T.3    Zhao, Z.4    McCurrach, M.5    Wang, X.6    Lowe, S.W.7
  • 38
    • 84860369516 scopus 로고    scopus 로고
    • Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis
    • A. Busca, M. Saxena, A. Kumar, Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis. J. Biol. Chem. 287, 15118-15133 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 15118-15133
    • Busca, A.1    Saxena, M.2    Kumar, A.3
  • 40
    • 0036337748 scopus 로고    scopus 로고
    • A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells
    • K. L. He, A. T. Ting, A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol. Cell. Biol. 22, 6034-6045 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6034-6045
    • He, K.L.1    Ting, A.T.2
  • 41
    • 34447507710 scopus 로고    scopus 로고
    • A20/TNFAIP3, a new estrogen-regulated gene that confers tamoxifen resistance in breast cancer cells
    • J. A. Vendrell, S. Ghayad, S. Ben-Larbi, C. Dumontet, N. Mechti, P. A. Cohen, A20/TNFAIP3, a new estrogen-regulated gene that confers tamoxifen resistance in breast cancer cells. Oncogene 26, 4656-4667 (2007).
    • (2007) Oncogene , vol.26 , pp. 4656-4667
    • Vendrell, J.A.1    Ghayad, S.2    Ben-Larbi, S.3    Dumontet, C.4    Mechti, N.5    Cohen, P.A.6
  • 44
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • S. L. Berger, The complex language of chromatin regulation during transcription. Nature 447, 407-412 (2007).
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 45
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • Z. Wang, M. Gerstein, M. Snyder, RNA-Seq: A revolutionary tool for transcriptomics. Nat. Rev. Genet. 10, 57-63 (2009).
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 47
    • 0141785046 scopus 로고    scopus 로고
    • Functional genomics as a window on radiation stress signaling
    • S. A. Amundson, M. Bittner, A. J. Fornace Jr., Functional genomics as a window on radiation stress signaling. Oncogene 22, 5828-5833 (2003).
    • (2003) Oncogene , vol.22 , pp. 5828-5833
    • Amundson, S.A.1    Bittner, M.2    Fornace Jr., A.J.3
  • 48
    • 70350343183 scopus 로고    scopus 로고
    • Cell response to ionising radiation analysed by gene expression patterns
    • L. Roy, G. Gruel, A. Vaurijoux, Cell response to ionising radiation analysed by gene expression patterns. Ann. Ist. Super. Sanita 45, 272-277 (2009).
    • (2009) Ann. Ist. Super. Sanita , vol.45 , pp. 272-277
    • Roy, L.1    Gruel, G.2    Vaurijoux, A.3
  • 53
    • 84862307800 scopus 로고    scopus 로고
    • Eukaryotic DNA damage checkpoint activation in response to double-strand breaks
    • K. Finn, N. F. Lowndes, M. Grenon, Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Cell. Mol. Life Sci. 69, 1447-1473 (2012).
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 1447-1473
    • Finn, K.1    Lowndes, N.F.2    Grenon, M.3
  • 54
    • 84055190692 scopus 로고    scopus 로고
    • Distinct p53 genomic binding patterns in normal and cancer-derived human cells
    • K. Botcheva, S. R. McCorkle, W. R. McCombie, J. J. Dunn, C. W. Anderson, Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle 10, 4237-4249 (2011).
    • (2011) Cell Cycle , vol.10 , pp. 4237-4249
    • Botcheva, K.1    McCorkle, S.R.2    McCombie, W.R.3    Dunn, J.J.4    Anderson, C.W.5
  • 57
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • ENCODE Project Consortium, B. E. Bernstein, E. Birney, I. Dunham, E. D. Green, C. Gunter, M. Snyder, An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
    • (2012) Nature , vol.489 , pp. 57-74
    • Bernstein, B.E.1    Birney, E.2    Dunham, I.3    Green, E.D.4    Gunter, C.5    Snyder, M.6
  • 58
    • 84856525447 scopus 로고    scopus 로고
    • Deconstructing p53 transcriptional networks in tumor suppression
    • K. T. Bieging, L. D. Attardi, Deconstructing p53 transcriptional networks in tumor suppression. Trends Cell Biol. 22, 97-106 (2012).
    • (2012) Trends Cell Biol. , vol.22 , pp. 97-106
    • Bieging, K.T.1    Attardi, L.D.2
  • 59
    • 84857443702 scopus 로고    scopus 로고
    • The p53 network: Cellular and systemic DNA damage responses in aging and cancer
    • H. C. Reinhardt, B. Schumacher, The p53 network: Cellular and systemic DNA damage responses in aging and cancer. Trends Genet. 28, 128-136 (2012).
    • (2012) Trends Genet. , vol.28 , pp. 128-136
    • Reinhardt, H.C.1    Schumacher, B.2
  • 61
    • 77954641944 scopus 로고    scopus 로고
    • Radiation-induced cell death mechanisms
    • D. Eriksson, T. Stigbrand, Radiation-induced cell death mechanisms. Tumour Biol. 31, 363-372 (2010).
    • (2010) Tumour Biol. , vol.31 , pp. 363-372
    • Eriksson, D.1    Stigbrand, T.2
  • 63
    • 84882450932 scopus 로고    scopus 로고
    • Various modes of cell death induced by DNA damage
    • O. Surova, B. Zhivotovsky, Various modes of cell death induced by DNA damage. Oncogene 32, 3789-3797 (2013).
    • (2013) Oncogene , vol.32 , pp. 3789-3797
    • Surova, O.1    Zhivotovsky, B.2
  • 64
    • 0035736138 scopus 로고    scopus 로고
    • If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
    • I. B. Roninson, E. V. Broude, B. D. Chang, If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist. Updat. 4, 303-313 (2001).
    • (2001) Drug Resist. Updat. , vol.4 , pp. 303-313
    • Roninson, I.B.1    Broude, E.V.2    Chang, B.D.3
  • 67
    • 84858722471 scopus 로고    scopus 로고
    • DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out
    • K. W. McCool, S. Miyamoto, DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. Immunol. Rev. 246, 311-326 (2012).
    • (2012) Immunol. Rev. , vol.246 , pp. 311-326
    • McCool, K.W.1    Miyamoto, S.2
  • 68
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • A. J. Bannister, T. Kouzarides, Regulation of chromatin by histone modifications. Cell Res. 21, 381-395 (2011).
    • (2011) Cell Res. , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 69
    • 79960600521 scopus 로고    scopus 로고
    • p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation
    • O. Laptenko, R. Beckerman, E. Freulich, C. Prives, p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation. Proc. Natl. Acad. Sci. U.S.A. 108, 10385-10390 (2011).
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 10385-10390
    • Laptenko, O.1    Beckerman, R.2    Freulich, E.3    Prives, C.4
  • 70
    • 78649264722 scopus 로고    scopus 로고
    • p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy
    • E. Lidor Nili, Y. Field, Y. Lubling, J. Widom, M. Oren, E. Segal, p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Res. 20, 1361-1368 (2010).
    • (2010) Genome Res. , vol.20 , pp. 1361-1368
    • Lidor Nili, E.1    Field, Y.2    Lubling, Y.3    Widom, J.4    Oren, M.5    Segal, E.6
  • 71
    • 79957547966 scopus 로고    scopus 로고
    • The protein kinase landscape of the DNA damage response
    • A. Bensimon, R. Aebersold, Y. Shiloh, Beyond ATM: The protein kinase landscape of the DNA damage response. FEBS Lett. 585, 1625-1639 (2011).
    • (2011) FEBS Lett. , vol.585 , pp. 1625-1639
    • Bensimon, A.1    Aebersold, R.2    Shiloh, Y.3    Beyond, A.T.M.4
  • 77
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • C. Trapnell, L. Pachter, S. L. Salzberg, TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 79
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • B. Langmead, C. Trapnell, M. Pop, S. L. Salzberg, Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10, R25 (2009).
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 80
    • 55749094855 scopus 로고    scopus 로고
    • An integrated software system for analyzing ChIP-chip and ChIP-seq data
    • H. Ji, H. Jiang, W. Ma, D. S. Johnson, R. M. Myers, W. H. Wong, An integrated software system for analyzing ChIP-chip and ChIP-seq data. Nat. Biotechnol. 26, 1293-1300 (2008).
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1293-1300
    • Ji, H.1    Jiang, H.2    Ma, W.3    Johnson, D.S.4    Myers, R.M.5    Wong, W.H.6
  • 81
    • 0028685490 scopus 로고
    • Fitting a mixture model by expectation maximization to discover motifs in biopolymers
    • T. L. Bailey, C. Elkan, Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Int. Conf. Intell. Syst. Mol. Biol. 2, 28-36 (1994).
    • (1994) Proc. Int. Conf. Intell. Syst. Mol. Biol. , vol.2 , pp. 28-36
    • Bailey, T.L.1    Elkan, C.2
  • 82
    • 46449123335 scopus 로고    scopus 로고
    • Transcription factor and microRNA motif discovery: The Amadeus platform and a compendium of metazoan target sets
    • C. Linhart, Y. Halperin, R. Shamir, Transcription factor and microRNA motif discovery: The Amadeus platform and a compendium of metazoan target sets. Genome Res. 18, 1180-1189 (2008).
    • (2008) Genome Res. , vol.18 , pp. 1180-1189
    • Linhart, C.1    Halperin, Y.2    Shamir, R.3
  • 84
    • 34548561818 scopus 로고    scopus 로고
    • beadarray: R classes and methods for Illumina bead-based data
    • M. J. Dunning, M. L. Smith, M. E. Ritchie, S. Tavaré, beadarray: R classes and methods for Illumina bead-based data. Bioinformatics 23, 2183-2184 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 2183-2184
    • Dunning, M.J.1    Smith, M.L.2    Ritchie, M.E.3    Tavaré, S.4
  • 85
    • 0141506116 scopus 로고    scopus 로고
    • CLICK and EXPANDER: A system for clustering and visualizing gene expression data
    • R. Sharan, A. Maron-Katz, R. Shamir, CLICK and EXPANDER: A system for clustering and visualizing gene expression data. Bioinformatics 19, 1787-1799 (2003).
    • (2003) Bioinformatics , vol.19 , pp. 1787-1799
    • Sharan, R.1    Maron-Katz, A.2    Shamir, R.3
  • 87
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • W. Huang da, B. T. Sherman, R. A. Lempicki, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protocols 4, 44-57 (2009).
    • (2009) Nat. Protocols , vol.4 , pp. 44-57
    • Da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.