메뉴 건너뛰기




Volumn 306, Issue 9, 2014, Pages

MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice

Author keywords

Bone marrow chimera; Colon cancer; Goll like receptors; Inflammation; MyD88

Indexed keywords

AZOXYMETHANE; DEXTRAN SULFATE; PROTEIN; PROTEIN MAL; UNCLASSIFIED DRUG;

EID: 84900534311     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00399.2013     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 75649093343 scopus 로고    scopus 로고
    • Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function
    • Abreu MT. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol 10: 131-144, 2010.
    • (2010) Nat Rev Immunol , vol.10 , pp. 131-144
    • Abreu, M.T.1
  • 4
    • 44349132270 scopus 로고    scopus 로고
    • Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
    • Artis D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 8: 411-420, 2008.
    • (2008) Nat Rev Immunol , vol.8 , pp. 411-420
    • Artis, D.1
  • 5
    • 77955346494 scopus 로고    scopus 로고
    • Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease
    • 529+e1-e2
    • Asquith MJ, Boulard O, Powrie F, Maloy KJ. Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease. Gastroenterology 139: 519-529, 529. e1-e2, 2010.
    • (2010) Gastroenterology , vol.139 , pp. 519-529
    • Asquith, M.J.1    Boulard, O.2    Powrie, F.3    Maloy, K.J.4
  • 6
    • 84893788667 scopus 로고    scopus 로고
    • A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner
    • Aviello G, Amu S, Saunders SP, Fallon PG. A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner. Phytother Res 28: 300-304, 2014.
    • (2014) Phytother Res , vol.28 , pp. 300-304
    • Aviello, G.1    Amu, S.2    Saunders, S.P.3    Fallon, P.G.4
  • 9
    • 84864320130 scopus 로고    scopus 로고
    • Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation
    • Boulard O, Kirchberger S, Royston DJ, Maloy KJ, Powrie FM. Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation. J Exp Med 209: 1309-1324, 2012.
    • (2012) J Exp Med , vol.209 , pp. 1309-1324
    • Boulard, O.1    Kirchberger, S.2    Royston, D.J.3    Maloy, K.J.4    Powrie, F.M.5
  • 10
    • 79959459365 scopus 로고    scopus 로고
    • Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-kappaB pathways in intestinal epithelial cells
    • Bruno ME, Frantz AL, Rogier EW, Johansen FE, Kaetzel CS. Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-kappaB pathways in intestinal epithelial cells. Mucosal Immunol 4: 468-478, 2011.
    • (2011) Mucosal Immunol , vol.4 , pp. 468-478
    • Bruno, M.E.1    Frantz, A.L.2    Rogier, E.W.3    Johansen, F.E.4    Kaetzel, C.S.5
  • 11
    • 77956289824 scopus 로고    scopus 로고
    • Toll-like receptors in inflammatory bowel diseases: A decade later
    • Cario E. Toll-like receptors in inflammatory bowel diseases: a decade later. Inflamm Bowel Dis 16: 1583-1597, 2010.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1583-1597
    • Cario, E.1
  • 12
    • 84871869646 scopus 로고    scopus 로고
    • PTEN regulates TLR5-induced intestinal inflammation by controlling Mal/TIRAP recruitment
    • Choi YJ, Jung J, Chung HK, Im E, Rhee SH. PTEN regulates TLR5-induced intestinal inflammation by controlling Mal/TIRAP recruitment. FASEB J 27: 243-254, 2013.
    • (2013) FASEB J , vol.27 , pp. 243-254
    • Choi, Y.J.1    Jung, J.2    Chung, H.K.3    Im, E.4    Rhee, S.H.5
  • 15
    • 84872445265 scopus 로고    scopus 로고
    • Neutralizing tumor-promoting chronic inflammation: A magic bullet?
    • Coussens LM, Zitvogel L, Palucka AK. Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 339: 286-291, 2013.
    • (2013) Science , vol.339 , pp. 286-291
    • Coussens, L.M.1    Zitvogel, L.2    Palucka, A.K.3
  • 17
    • 61349149941 scopus 로고    scopus 로고
    • Principles of bone marrow transplantation (BMT): Providing optimal veterinary and husbandry care to irradiated mice in BMT studies
    • Duran-Struuck R, Dysko RC. Principles of bone marrow transplantation (BMT): providing optimal veterinary and husbandry care to irradiated mice in BMT studies. J Am Assoc Lab Anim Sci 48: 11-22, 2009.
    • (2009) J Am Assoc Lab Anim Sci , vol.48 , pp. 11-22
    • Duran-Struuck, R.1    Dysko, R.C.2
  • 20
    • 84864886608 scopus 로고    scopus 로고
    • Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides
    • Frantz AL, Rogier EW, Weber CR, Shen L, Cohen DA, Fenton LA, Bruno ME, Kaetzel CS. Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol 5: 501-512, 2012.
    • (2012) Mucosal Immunol , vol.5 , pp. 501-512
    • Frantz, A.L.1    Rogier, E.W.2    Weber, C.R.3    Shen, L.4    Cohen, D.A.5    Fenton, L.A.6    Bruno, M.E.7    Kaetzel, C.S.8
  • 21
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 140: 883-899, 2010.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 22
    • 0027424646 scopus 로고
    • Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated
    • Hermiston ML, Green RP, Gordon JI. Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated. Proc Natl Acad Sci USA 90: 8866-8870, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8866-8870
    • Hermiston, M.L.1    Green, R.P.2    Gordon, J.I.3
  • 23
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T, Barton GM, Flavell RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420: 329-333, 2002.
    • (2002) Nature , vol.420 , pp. 329-333
    • Horng, T.1    Barton, G.M.2    Flavell, R.A.3    Medzhitov, R.4
  • 24
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng T, Barton GM, Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2: 835-841, 2001.
    • (2001) Nat Immunol , vol.2 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 27
    • 84862804952 scopus 로고    scopus 로고
    • Accessory molecules for Toll-like receptors and their function
    • Lee CC, Avalos AM, Ploegh HL. Accessory molecules for Toll-like receptors and their function. Nat Rev Immunol 12: 168-179, 2012.
    • (2012) Nat Rev Immunol , vol.12 , pp. 168-179
    • Lee, C.C.1    Avalos, A.M.2    Ploegh, H.L.3
  • 28
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy KJ, Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 474: 298-306, 2011.
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 29
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature 454: 428-435, 2008.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 32
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM, Karin M. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317: 121-124, 2007.
    • (2007) Science , vol.317 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3    Maeda, S.4    Kim, K.5    Elsharkawy, A.M.6    Karin, M.7
  • 33
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • Neufert C, Becker C, Neurath MF. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat Protoc 2: 1998-2004, 2007.
    • (2007) Nat Protoc , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 34
    • 84878349644 scopus 로고    scopus 로고
    • Five-year mortality in colorectal cancer patients with ulcerative colitis or Crohn's disease: A nationwide population-based cohort study
    • Ording AG, Horvath-Puho E, Erichsen R, Long MD, Baron JA, Lash TL, Sorensen HT. Five-year mortality in colorectal cancer patients with ulcerative colitis or Crohn's disease: a nationwide population-based cohort study. Inflamm Bowel Dis 19: 800-805, 2013.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 800-805
    • Ording, A.G.1    Horvath-Puho, E.2    Erichsen, R.3    Long, M.D.4    Baron, J.A.5    Lash, T.L.6    Sorensen, H.T.7
  • 35
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 347: 417-429, 2002.
    • (2002) N Engl J Med , vol.347 , pp. 417-429
    • Podolsky, D.K.1
  • 36
    • 34447296425 scopus 로고    scopus 로고
    • Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
    • Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 317: 124-127, 2007.
    • (2007) Science , vol.317 , pp. 124-127
    • Rakoff-Nahoum, S.1    Medzhitov, R.2
  • 37
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118: 229-241, 2004.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 40
    • 78650624793 scopus 로고    scopus 로고
    • Innate immune mechanisms of colitis and colitis-associated colorectal cancer
    • Saleh M, Trinchieri G. Innate immune mechanisms of colitis and colitis-associated colorectal cancer. Nat Rev Immunol 11: 9-20, 2011.
    • (2011) Nat Rev Immunol , vol.11 , pp. 9-20
    • Saleh, M.1    Trinchieri, G.2
  • 42
    • 84888638819 scopus 로고    scopus 로고
    • The microbiome and cancer
    • Schwabe RF, Jobin C. The microbiome and cancer. Nat Rev Cancer 13: 800-812, 2013.
    • (2013) Nat Rev Cancer , vol.13 , pp. 800-812
    • Schwabe, R.F.1    Jobin, C.2
  • 44
    • 84868266897 scopus 로고    scopus 로고
    • Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS)
    • Thaker AI, Shaker A, Rao MS, Ciorba MA. Modeling colitis-associated cancer with azoxymethane (AOM) and dextran sulfate sodium (DSS). J Vis Exp 67: 4100, 2012.
    • (2012) J Vis Exp , vol.67 , pp. 4100
    • Thaker, A.I.1    Shaker, A.2    Rao, M.S.3    Ciorba, M.A.4
  • 46
    • 69949183194 scopus 로고    scopus 로고
    • MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2-and TLR4-mediated NF-kappaB proinflammatory responses
    • Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A. MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2-and TLR4-mediated NF-kappaB proinflammatory responses. J Biol Chem 284: 24192-24203, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 24192-24203
    • Verstak, B.1    Nagpal, K.2    Bottomley, S.P.3    Golenbock, D.T.4    Hertzog, P.J.5    Mansell, A.6
  • 47
    • 77649272127 scopus 로고    scopus 로고
    • High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer
    • Wang EL, Qian ZR, Nakasono M, Tanahashi T, Yoshimoto K, Bando Y, Kudo E, Shimada M, Sano T. High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer. Br J Cancer 102: 908-915, 2010.
    • (2010) Br J Cancer , vol.102 , pp. 908-915
    • Wang, E.L.1    Qian, Z.R.2    Nakasono, M.3    Tanahashi, T.4    Yoshimoto, K.5    Bando, Y.6    Kudo, E.7    Shimada, M.8    Sano, T.9
  • 48
    • 77955909527 scopus 로고    scopus 로고
    • NF-kappaB-mediated expression of MAPK phosphatase-1 is an early step in desensitization to TLR ligands in enterocytes
    • Wang J, Ford HR, Grishin AV. NF-kappaB-mediated expression of MAPK phosphatase-1 is an early step in desensitization to TLR ligands in enterocytes. Mucosal Immunol 3: 523-534, 2010.
    • (2010) Mucosal Immunol , vol.3 , pp. 523-534
    • Wang, J.1    Ford, H.R.2    Grishin, A.V.3
  • 49
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434, 2007.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.