-
1
-
-
51849084360
-
The PTEN-PI3K pathway: Of feedbacks and cross-talks
-
Carracedo, A., and Pandolfi, P. P. (2008) The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene 27, 5527-5541
-
(2008)
Oncogene
, vol.27
, pp. 5527-5541
-
-
Carracedo, A.1
Pandolfi, P.P.2
-
2
-
-
58049220365
-
Pattern recognition receptors and control of adaptive immunity
-
Palm, N. W., and Medzhitov, R. (2009) Pattern recognition receptors and control of adaptive immunity. Immunol. Rev. 227, 221-233
-
(2009)
Immunol. Rev.
, vol.227
, pp. 221-233
-
-
Palm, N.W.1
Medzhitov, R.2
-
3
-
-
2942560322
-
MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells
-
DOI 10.1074/jbc.M400967200
-
Rhee, S. H., Keates, A. C., Moyer, M. P., and Pothoulakis, C. (2004) MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. J. Biol. Chem. 279, 25179-25188 (Pubitemid 38756768)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.24
, pp. 25179-25188
-
-
Rhee, S.H.1
Keates, A.C.2
Moyer, M.P.3
Pothoulakis, C.4
-
4
-
-
47249131603
-
Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease
-
Blohmke, C. J., Victor, R. E., Hirschfeld, A. F., Elias, I. M., Hancock, D. G., Lane, C. R., Davidson, A. G., Wilcox, P. G., Smith, K. D., Overhage, J., Hancock, R. E., and Turvey, S. E. (2008) Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease. J. Immunol. 180, 7764-7773
-
(2008)
J. Immunol.
, vol.180
, pp. 7764-7773
-
-
Blohmke, C.J.1
Victor, R.E.2
Hirschfeld, A.F.3
Elias, I.M.4
Hancock, D.G.5
Lane, C.R.6
Davidson, A.G.7
Wilcox, P.G.8
Smith, K.D.9
Overhage, J.10
Hancock, R.E.11
Turvey, S.E.12
-
5
-
-
3042789092
-
Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells
-
DOI 10.1111/j.1365-2567.2004.01898.x
-
Schaefer, T. M., Desouza, K., Fahey, J. V., Beagley, K. W., and Wira, C. R. (2004) Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells. Immunology 112, 428-436 (Pubitemid 38859521)
-
(2004)
Immunology
, vol.112
, Issue.3
, pp. 428-436
-
-
Schaefer, T.M.1
Desouza, K.2
Fahey, J.V.3
Beagley, K.W.4
Wira, C.R.5
-
6
-
-
45549099429
-
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
-
DOI 10.1038/ni.1622, PII NI.1622
-
Uematsu, S., Fujimoto, K., Jang, M. H., Yang, B. G., Jung, Y. J., Nishiyama, M., Sato, S., Tsujimura, T., Yamamoto, M., Yokota, Y., Kiyono, H., Miyasaka, M., Ishii, K. J., and Akira, S. (2008) Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat. Immunol. 9, 769-776 (Pubitemid 351859160)
-
(2008)
Nature Immunology
, vol.9
, Issue.7
, pp. 769-776
-
-
Uematsu, S.1
Fujimoto, K.2
Jang, M.H.3
Yang, B.-G.4
Jung, Y.-J.5
Nishiyama, M.6
Sato, S.7
Tsujimura, T.8
Yamamoto, M.9
Yokota, Y.10
Kiyono, H.11
Miyasaka, M.12
Ishii, K.J.13
Akira, S.14
-
7
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar, M., Aitken, J. D., Carvalho, F. A., Cullender, T. C., Mwangi, S., Srinivasan, S., Sitaraman, S. V., Knight, R., Ley, R. E., and Gewirtz, A. T. (2010) Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328, 228-231
-
(2010)
Science
, vol.328
, pp. 228-231
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Carvalho, F.A.3
Cullender, T.C.4
Mwangi, S.5
Srinivasan, S.6
Sitaraman, S.V.7
Knight, R.8
Ley, R.E.9
Gewirtz, A.T.10
-
8
-
-
36849000520
-
Deletion of TLR5 results in spontaneous colitis in mice
-
DOI 10.1172/JCI33084
-
Vijay-Kumar, M., Sanders, C. J., Taylor, R. T., Kumar, A., Aitken, J. D., Sitaraman, S. V., Neish, A. S., Uematsu, S., Akira, S., Williams, I. R., and Gewirtz, A. T. (2007) Deletion of TLR5 results in spontaneous colitis in mice. J. Clin. Invest. 117, 3909-3921 (Pubitemid 350224100)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3909-3921
-
-
Vijay-Kumar, M.1
Sanders, C.J.2
Taylor, R.T.3
Kumar, A.4
Aitken, J.D.5
Sitaraman, S.V.6
Neish, A.S.7
Uematsu, S.8
Akira, S.9
Williams, I.R.10
Gewirtz, A.T.11
-
9
-
-
33747769371
-
Involvement of toll-like receptor 5 in the recognition of flagellated bacteria
-
DOI 10.1073/pnas.0605200103
-
Feuillet, V., Medjane, S., Mondor, I., Demaria, O., Pagni, P. P., Galan, J. E., Flavell, R. A., and Alexopoulou, L. (2006) Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc. Natl. Acad. Sci. U. S. A. 103, 12487-12492 (Pubitemid 44274883)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.33
, pp. 12487-12492
-
-
Feuillet, V.1
Medjane, S.2
Mondor, I.3
Demaria, O.4
Pagni, P.P.5
Galan, J.E.6
Flavell, R.A.7
Alexopoulou, L.8
-
10
-
-
79955527226
-
TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen
-
Letran, S. E., Lee, S. J., Atif, S. M., Flores-Langarica, A., Uematsu, S., Akira, S., Cunningham, A. F., and McSorley, S. J. (2011) TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen. J. Immunol. 186, 5406-5412
-
(2011)
J. Immunol.
, vol.186
, pp. 5406-5412
-
-
Letran, S.E.1
Lee, S.J.2
Atif, S.M.3
Flores-Langarica, A.4
Uematsu, S.5
Akira, S.6
Cunningham, A.F.7
McSorley, S.J.8
-
11
-
-
2342646956
-
Bacterial flagellin is a dominant antigen in Crohn disease
-
DOI 10.1172/JCI200420295
-
Lodes, M. J., Cong, Y., Elson, C. O., Mohamath, R., Landers, C. J., Targan, S. R., Fort, M., and Hershberg, R. M. (2004) Bacterial flagellin is a dominant antigen in Crohn disease. J. Clin. Invest. 113, 1296-1306 (Pubitemid 39069929)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.9
, pp. 1296-1306
-
-
Lodes, M.J.1
Cong, Y.2
Elson, C.O.3
Mohamath, R.4
Landers, C.J.5
Targan, S.R.6
Fort, M.7
Hershberg, R.M.8
-
12
-
-
26444440067
-
Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagenllin in colonic inflammation
-
DOI 10.1073/pnas.0502174102
-
Rhee, S. H., Im, E., Riegler, M., Kokkotou, E., O'Brien, M., and Pothoulakis, C. (2005) Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc. Natl. Acad. Sci. U. S. A. 102, 13610-13615 (Pubitemid 41420896)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13610-13615
-
-
Rhee, S.H.1
Im, E.2
Riegler, M.3
Kokkotou, E.4
O'Brien, M.5
Pothoulakis, C.6
-
13
-
-
49749149169
-
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin
-
Carvalho, F. A., Barnich, N., Sauvanet, P., Darcha, C., Gelot, A., and Darfeuille-Michaud, A. (2008) Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin. Inflamm. Bowel Dis. 14, 1051-1060
-
(2008)
Inflamm. Bowel Dis.
, vol.14
, pp. 1051-1060
-
-
Carvalho, F.A.1
Barnich, N.2
Sauvanet, P.3
Darcha, C.4
Gelot, A.5
Darfeuille-Michaud, A.6
-
14
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C., Ghosh, S., and Janeway, C. A., Jr. (1998) MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell 2, 253-258 (Pubitemid 128373651)
-
(1998)
Molecular Cell
, vol.2
, Issue.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway Jr., C.A.7
-
15
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for toll-like recepfor-4 signal transduction
-
DOI 10.1038/35092578
-
Fitzgerald, K. A., Palsson-McDermott, E. M., Bowie, A. G., Jefferies, C. A., Mansell, A. S., Brady, G., Brint, E., Dunne, A., Gray, P., Harte, M. T., McMurray, D., Smith, D. E., Sims, J. E., Bird, T. A., and O'Neill, L. A. (2001) Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413, 78-83 (Pubitemid 32843491)
-
(2001)
Nature
, vol.413
, Issue.6851
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-Mcdermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
McMurray, D.11
Smith, D.E.12
Sims, J.E.13
Bird, T.A.14
O'Neill, L.A.J.15
-
16
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng, T., Barton, G. M., and Medzhitov, R. (2001) TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2, 835-841
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
17
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K., and Akira, S. (2002) Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J. Immunol. 169, 6668-6672 (Pubitemid 36899248)
-
(2002)
Journal of Immunology
, vol.169
, Issue.12
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
18
-
-
0042591216
-
TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
-
Bin, L. H., Xu, L. G., and Shu, H. B. (2003) TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J. Biol. Chem. 278, 24526-24532
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24526-24532
-
-
Bin, L.H.1
Xu, L.G.2
Shu, H.B.3
-
19
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
DOI 10.1038/ni986
-
Yamamoto, M., Sato, S., Hemmi, H., Uematsu, S., Hoshino, K., Kaisho, T., Takeuchi, O., Takeda, K., and Akira, S. (2003) TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat. Immunol. 4, 1144-1150 (Pubitemid 37428043)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1144-1150
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
Takeuchi, O.7
Takeda, K.8
Akira, S.9
-
20
-
-
78549284013
-
TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells
-
Choi, Y. J., Im, E., Chung, H. K., Pothoulakis, C., and Rhee, S. H. (2010) TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells. J. Biol. Chem. 285, 37570-37578
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37570-37578
-
-
Choi, Y.J.1
Im, E.2
Chung, H.K.3
Pothoulakis, C.4
Rhee, S.H.5
-
21
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
DOI 10.1016/0092-8674(93)80068-P
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W. (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274 (Pubitemid 23320290)
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
22
-
-
0036195102
-
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
-
DOI 10.1002/gene.10036
-
Lesche, R., Groszer, M., Gao, J., Wang, Y., Messing, A., Sun, H., Liu, X., and Wu, H. (2002) Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 32, 148-149 (Pubitemid 34211723)
-
(2002)
Genesis
, vol.32
, Issue.2
, pp. 148-149
-
-
Lesche, R.1
Groszer, M.2
Gao, J.3
Wang, Y.4
Messing, A.5
Sun, H.6
Liu, X.7
Wu, H.8
-
23
-
-
0037031856
-
cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
-
DOI 10.1074/jbc.M204935200
-
Madison, B. B., Dunbar, L., Qiao, X. T., Braunstein, K., Braunstein, E., and Gumucio, D. L. (2002) Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J. Biol. Chem. 277, 33275-33283 (Pubitemid 34984848)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.36
, pp. 33275-33283
-
-
Madison, B.B.1
Dunbar, L.2
Qiao, X.T.3
Braunstein, K.4
Braunstein, E.5
Gumucio, D.L.6
-
24
-
-
67649380840
-
Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia
-
Langlois, M. J., Roy, S. A., Auclair, B. A., Jones, C., Boudreau, F., Carrier, J. C., Rivard, N., and Perreault, N. (2009) Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia. FASEB J. 23, 1835-1844
-
(2009)
FASEB J.
, vol.23
, pp. 1835-1844
-
-
Langlois, M.J.1
Roy, S.A.2
Auclair, B.A.3
Jones, C.4
Boudreau, F.5
Carrier, J.C.6
Rivard, N.7
Perreault, N.8
-
25
-
-
77954381441
-
TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5
-
Choi, Y. J., Im, E., Pothoulakis, C., and Rhee, S. H. (2010) TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5. J. Biol. Chem. 285, 21382-21390
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 21382-21390
-
-
Choi, Y.J.1
Im, E.2
Pothoulakis, C.3
Rhee, S.H.4
-
26
-
-
0034602150
-
Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase
-
Rhee, S. H., and Hwang, D. (2000) Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase. J. Biol. Chem. 275, 34035-34040
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34035-34040
-
-
Rhee, S.H.1
Hwang, D.2
-
27
-
-
33745868678
-
Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells
-
DOI 10.1074/jbc.M513861200
-
Rhee, S. H., Kim, H., Moyer, M. P., and Pothoulakis, C. (2006) Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells. J. Biol. Chem. 281, 18560-18568 (Pubitemid 44035515)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.27
, pp. 18560-18568
-
-
Sang, H.R.1
Kim, H.2
Moyer, M.P.3
Pothoulakis, C.4
-
28
-
-
35948956639
-
Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras
-
DOI 10.1158/0008-5472.CAN-07-1827
-
Vasudevan, K. M., Burikhanov, R., Goswami, A., and Rangnekar, V. M. (2007) Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras. Cancer Res. 67, 10343-10350 (Pubitemid 350070809)
-
(2007)
Cancer Research
, vol.67
, Issue.21
, pp. 10343-10350
-
-
Vasudevan, K.M.1
Burikhanov, R.2
Goswami, A.3
Rangnekar, V.M.4
-
29
-
-
0343183328
-
Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
-
DOI 10.1016/S0960-9822(00)00417-6
-
Liliental, J., Moon, S. Y., Lesche, R., Mamillapalli, R., Li, D., Zheng, Y., Sun, H., and Wu, H. (2000) Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases. Curr. Biol. 10, 401-404 (Pubitemid 30213387)
-
(2000)
Current Biology
, vol.10
, Issue.7
, pp. 401-404
-
-
Liliental, J.1
Moon, S.Y.2
Lesche, R.3
Mamillapalli, R.4
Li, D.5
Zheng, Y.6
Sun, H.7
Wu, H.8
-
30
-
-
81255158786
-
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
-
Song, X., Zhu, S., Shi, P., Liu, Y., Shi, Y., Levin, S. D., and Qian, Y. (2011) IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat. Immunol. 12, 1151-1158
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1151-1158
-
-
Song, X.1
Zhu, S.2
Shi, P.3
Liu, Y.4
Shi, Y.5
Levin, S.D.6
Qian, Y.7
-
31
-
-
0037474303
-
HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains
-
DOI 10.1074/jbc.M207371200
-
Percherancier, Y., Lagane, B., Planchenault, T., Staropoli, I., Altmeyer, R., Virelizier, J. L., Arenzana-Seisdedos, F., Hoessli, D. C., and Bachelerie, F. (2003) HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains. J. Biol. Chem. 278, 3153-3161 (Pubitemid 36805610)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.5
, pp. 3153-3161
-
-
Percherancier, Y.1
Lagane, B.2
Planchenault, T.3
Staropoli, I.4
Altmeyer, R.5
Virelizier, J.-L.6
Arenzana-Seisdedos, F.7
Hoessli, D.C.8
Bachelerie, F.9
-
32
-
-
33646777129
-
Regulating angiogenesis at the level of PtdIns-4,5-P2
-
Im, E., and Kazlauskas, A. (2006) Regulating angiogenesis at the level of PtdIns-4,5-P2. EMBO J. 25, 2075-2082
-
(2006)
EMBO J.
, vol.25
, pp. 2075-2082
-
-
Im, E.1
Kazlauskas, A.2
-
33
-
-
0036308972
-
A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
-
Weiner, O. D., Neilsen, P. O., Prestwich, G. D., Kirschner, M. W., Cantley, L. C., and Bourne, H. R. (2002) A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat. Cell Biol. 4, 509-513
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 509-513
-
-
Weiner, O.D.1
Neilsen, P.O.2
Prestwich, G.D.3
Kirschner, M.W.4
Cantley, L.C.5
Bourne, H.R.6
-
34
-
-
70349311440
-
Bacillus polyfermenticus ameliorates colonic inflammation by promoting cytoprotective effects in colitic mice
-
Im, E., Choi, Y. J., Pothoulakis, C., and Rhee, S. H. (2009) Bacillus polyfermenticus ameliorates colonic inflammation by promoting cytoprotective effects in colitic mice. J. Nutr. 139, 1848-1854
-
(2009)
J. Nutr.
, vol.139
, pp. 1848-1854
-
-
Im, E.1
Choi, Y.J.2
Pothoulakis, C.3
Rhee, S.H.4
-
35
-
-
33747114270
-
Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis
-
DOI 10.1016/j.immuni.2006.06.010, PII S107476130600344X
-
Rakoff-Nahoum, S., Hao, L., and Medzhitov, R. (2006) Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity 25, 319-329 (Pubitemid 44224143)
-
(2006)
Immunity
, vol.25
, Issue.2
, pp. 319-329
-
-
Rakoff-Nahoum, S.1
Hao, L.2
Medzhitov, R.3
-
36
-
-
70449188638
-
Current status of therapy in regional ileitis
-
Crohn, B. B. (1958) Current status of therapy in regional ileitis. J. Am. Med. Assoc. 166, 1479-1480
-
(1958)
J. Am. Med. Assoc.
, vol.166
, pp. 1479-1480
-
-
Crohn, B.B.1
-
37
-
-
34548679608
-
TLR5 and Ipaf: Dual sensors of bacterial flagellin in the innate immune system
-
DOI 10.1007/s00281-007-0078-z, The NLR-related Disorders
-
Miao, E. A., Andersen-Nissen, E., Warren, S. E., and Aderem, A. (2007) TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Semin. Immunopathol. 29, 275-288 (Pubitemid 47416216)
-
(2007)
Seminars in Immunopathology
, vol.29
, Issue.3
, pp. 275-288
-
-
Miao, E.A.1
Andersen-Nissen, E.2
Warren, S.E.3
Aderem, A.4
-
38
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
DOI 10.1038/ni1346, PII N1346
-
Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T. D., Ozoren, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., Grant, E. P., and Nunez, G. (2006) Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat. Immunol. 7, 576-582 (Pubitemid 43797338)
-
(2006)
Nature Immunology
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.-D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
39
-
-
67649814136
-
PI3K/PTEN signaling in angiogenesis and tumorigenesis
-
Jiang, B. H., and Liu, L. Z. (2009) PI3K/PTEN signaling in angiogenesis and tumorigenesis. Adv. Cancer Res. 102, 19-65
-
(2009)
Adv. Cancer Res.
, vol.102
, pp. 19-65
-
-
Jiang, B.H.1
Liu, L.Z.2
-
40
-
-
33646908228
-
Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling
-
DOI 10.1016/j.cell.2006.03.047, PII S0092867406005617
-
Kagan, J. C., and Medzhitov, R. (2006) Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125, 943-955 (Pubitemid 43795199)
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
41
-
-
0035424901
-
Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu, M. T., Vora, P., Faure, E., Thomas, L. S., Arnold, E. T., and Arditi, M. (2001) Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J. Immunol. 167, 1609-1616 (Pubitemid 32703162)
-
(2001)
Journal of Immunology
, vol.167
, Issue.3
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
Thomas, L.S.4
Arnold, E.T.5
Arditi, M.6
-
42
-
-
0037307854
-
Human intestinal epithelial cells are broadly unresponsive to toll-like receptor 2-dependent bacterial ligands: Implications for host-microbial interactions in the gut
-
Melmed, G., Thomas, L. S., Lee, N., Tesfay, S. Y., Lukasek, K., Michelsen, K. S., Zhou, Y., Hu, B., Arditi, M., and Abreu, M. T. (2003) Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J. Immunol. 170, 1406-1415 (Pubitemid 36139508)
-
(2003)
Journal of Immunology
, vol.170
, Issue.3
, pp. 1406-1415
-
-
Melmed, G.1
Thomas, L.S.2
Lee, N.3
Tesfay, S.Y.4
Lukasek, K.5
Michelsen, K.S.6
Zhou, Y.7
Hu, B.8
Arditi, M.9
Abreu, M.T.10
-
43
-
-
48549106083
-
Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer
-
Rhee, S. H., Im, E., and Pothoulakis, C. (2008) Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. Gastroenterology 135, 518-528
-
(2008)
Gastroenterology
, vol.135
, pp. 518-528
-
-
Rhee, S.H.1
Im, E.2
Pothoulakis, C.3
-
44
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J., and Madara, J. L. (2001) Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167, 1882-1885 (Pubitemid 32747491)
-
(2001)
Journal of Immunology
, vol.167
, Issue.4
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
45
-
-
0036251680
-
Reprogramming fibroblasts to express T-cell functions using cell extracts
-
DOI 10.1038/nbt0502-460
-
Hakelien, A. M., Landsverk, H. B., Robl, J. M., Skalhegg, B. S., and Collas, P. (2002) Reprogramming fibroblasts to express T-cell functions using cell extracts. Nat. Biotechnol. 20, 460-466 (Pubitemid 34495931)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.5
, pp. 460-466
-
-
Hakelien, A.-M.1
Landsverk, H.B.2
Robl, J.M.3
Skalhegg, B.S.4
Collas, P.5
|