Mammalian TBX1 preferentially binds and regulates downstream targets via a tandem T-site repeat

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Castellanos, Raquel ^a   Xie, Qing ^a   Zheng, Deyou ^a   Cvekl, Ales ^a   Morrow, Bernice E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; T BOX TRANSCRIPTION FACTOR; PROTEIN BINDING; TBX1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; BMPER GENE; CELL CULTURE; CELLULAR DISTRIBUTION; COMBINATORIAL CHEMISTRY; COMPUTER MODEL; CONTROLLED STUDY; FGF8 GENE; GENE; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; IN VITRO STUDY; LUCIFERASE ASSAY; MISSENSE MUTATION; MOUSE; NONHUMAN; OTOG MYOD GENE; PROTEIN MOTIF; REGULATORY MECHANISM; TANDEM REPEAT; TBX1 GENE; TRANSCRIPTION REGULATION; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; DIGEORGE SYNDROME; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; METABOLISM; MUTANT MOUSE STRAIN;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; DIGEORGE SYNDROME; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICE; MICE, MUTANT STRAINS; MUTATION, MISSENSE; PROTEIN BINDING; RESPONSE ELEMENTS; T-BOX DOMAIN PROTEINS; TANDEM REPEAT SEQUENCES; TRANSCRIPTION, GENETIC;

EID: 84900432339     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095151     Document Type: Article

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