메뉴 건너뛰기




Volumn 24, Issue 2, 2000, Pages 139-143

Targeted disruption of Otog results in deafness and severe imbalance

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COCHLEA DUCT; GENE DISRUPTION; GENE EXPRESSION; GENE ISOLATION; GENE TARGETING; HAIR CELL; HEARING IMPAIRMENT; INNER EAR; MOUSE; NONHUMAN; PRIORITY JOURNAL; VESTIBULAR FUNCTION;

EID: 0033951215     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/72793     Document Type: Article
Times cited : (134)

References (30)
  • 1
    • 0029807805 scopus 로고    scopus 로고
    • Genes responsible for human hereditary deafness: Symphony of a thousand
    • Petit, C. Genes responsible for human hereditary deafness: symphony of a thousand. Nature Genet. 14, 385-391 (1996).
    • (1996) Nature Genet. , vol.14 , pp. 385-391
    • Petit, C.1
  • 2
    • 0031443872 scopus 로고    scopus 로고
    • Otogelin: A glycoprotein specific to the acellular membranes of the inner ear
    • Cohen-Salmon, M., El-Amraoui, A., Leibovici, M. & Petit, C. Otogelin: a glycoprotein specific to the acellular membranes of the inner ear. Proc. Natl Acad. Sci. USA 94, 14450-14455 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 14450-14455
    • Cohen-Salmon, M.1    El-Amraoui, A.2    Leibovici, M.3    Petit, C.4
  • 3
    • 0024433313 scopus 로고
    • How the ear's works work
    • Hudspeth, A.J. How the ear's works work. Nature 341, 397-404 (1989).
    • (1989) Nature , vol.341 , pp. 397-404
    • Hudspeth, A.J.1
  • 4
    • 0025005344 scopus 로고
    • Sodium arsanilate-induced vestibular dysfunction in rats: Effects of open-field behavior and spontaneous activity in the automated digiscan monitoring system
    • Ossenkopp, K.P., Prkacin, A. & Hargreaves, E.L. Sodium arsanilate-induced vestibular dysfunction in rats: effects of open-field behavior and spontaneous activity in the automated digiscan monitoring system. Pharmacol. Biochem. Behav. 36, 875-881 (1990).
    • (1990) Pharmacol. Biochem. Behav. , vol.36 , pp. 875-881
    • Ossenkopp, K.P.1    Prkacin, A.2    Hargreaves, E.L.3
  • 5
    • 0025108084 scopus 로고
    • An open-field activity analysis of labyrinthectomized rats
    • Porter, J.D., Pellis, S.M. & Meyer, M.E. An open-field activity analysis of labyrinthectomized rats. Physiol. Behav. 48, 27-30 (1990).
    • (1990) Physiol. Behav. , vol.48 , pp. 27-30
    • Porter, J.D.1    Pellis, S.M.2    Meyer, M.E.3
  • 6
    • 0027491851 scopus 로고
    • The behavioral syndrome caused by 3,3′-iminodipropionitrile and related nitriles in the rat is associated with degeneration of the vestibular sensory hair cells
    • Liorens, J., Dermenes, D. & Sans, A. The behavioral syndrome caused by 3,3′-iminodipropionitrile and related nitriles in the rat is associated with degeneration of the vestibular sensory hair cells. Toxicol. Applied Pharmacol. 123, 199-210 (1993).
    • (1993) Toxicol. Applied Pharmacol. , vol.123 , pp. 199-210
    • Liorens, J.1    Dermenes, D.2    Sans, A.3
  • 7
    • 0018386571 scopus 로고
    • Auditory nerve and brain stem volume-conducted potentials by pure-tone pips in the CBA/J laboratory mouse
    • Henry, K.R. Auditory nerve and brain stem volume-conducted potentials by pure-tone pips in the CBA/J laboratory mouse. Audiology 18, 93-108 (1979).
    • (1979) Audiology , vol.18 , pp. 93-108
    • Henry, K.R.1
  • 8
    • 0030889074 scopus 로고    scopus 로고
    • The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system
    • Legan, P.K., Rau, A., Keen, J.N. & Richardson, G.P. The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system. J. Biol. Chem. 272, 8791-8801 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 8791-8801
    • Legan, P.K.1    Rau, A.2    Keen, J.N.3    Richardson, G.P.4
  • 9
    • 0033535316 scopus 로고    scopus 로고
    • Tectorin mRNA expression is spatially and temporally restricted during mouse inner ear development
    • Rau, A., Legan, P.K. & Richardson, G.P. Tectorin mRNA expression is spatially and temporally restricted during mouse inner ear development. J. Comp. Neurol. 405, 271-280 (1999).
    • (1999) J. Comp. Neurol. , vol.405 , pp. 271-280
    • Rau, A.1    Legan, P.K.2    Richardson, G.P.3
  • 10
    • 0028106530 scopus 로고
    • Immunohistochemical localization of keratan sulfate and chondroitin 4- and 6-sulfate proteoglycans in subregions of the tectorial and basilar membranes
    • Munyer, P.D. & Schulte, B.A. Immunohistochemical localization of keratan sulfate and chondroitin 4- and 6-sulfate proteoglycans in subregions of the tectorial and basilar membranes. Hearing Res. 79, 83-93 (1994).
    • (1994) Hearing Res. , vol.79 , pp. 83-93
    • Munyer, P.D.1    Schulte, B.A.2
  • 11
    • 0015403485 scopus 로고
    • Fine morphology of the tectorial membrane. Its relationship to the organ of Corti
    • Lim, D.J. Fine morphology of the tectorial membrane. Its relationship to the organ of Corti. Arch. Otolaryngol. 96, 199-215 (1972).
    • (1972) Arch. Otolaryngol. , vol.96 , pp. 199-215
    • Lim, D.J.1
  • 12
    • 0018172093 scopus 로고
    • Ultrastructure of the different zones of the tectorial membrane
    • Kronester-Frei, A. Ultrastructure of the different zones of the tectorial membrane. Cell Tissue Res. 193, 11-23 (1978).
    • (1978) Cell Tissue Res. , vol.193 , pp. 11-23
    • Kronester-Frei, A.1
  • 13
    • 0023759376 scopus 로고
    • The ultrastructural organization and properties of the mouse tectorial membrane matrix
    • Hasko, J.A. & Richardson, G.P. The ultrastructural organization and properties of the mouse tectorial membrane matrix. Hearing Res. 35, 21-38 (1988).
    • (1988) Hearing Res. , vol.35 , pp. 21-38
    • Hasko, J.A.1    Richardson, G.P.2
  • 14
    • 0030757333 scopus 로고    scopus 로고
    • Ultrastructure organization of proteoglycans and fibrillar matrix of the tectorial membrane
    • Tsuprun, V. & Santi, P. Ultrastructure organization of proteoglycans and fibrillar matrix of the tectorial membrane. Hearing Res. 110, 107-118 (1997).
    • (1997) Hearing Res. , vol.110 , pp. 107-118
    • Tsuprun, V.1    Santi, P.2
  • 15
    • 0026515616 scopus 로고
    • Type II and type IX collagen form heterotypic fibers in the tectorial membrane of the inner ear
    • Slepecky, N.B., Cefaratti, L.K. & Yoo, T.J. Type II and type IX collagen form heterotypic fibers in the tectorial membrane of the inner ear. Matrix 12, 80-86 (1992).
    • (1992) Matrix , vol.12 , pp. 80-86
    • Slepecky, N.B.1    Cefaratti, L.K.2    Yoo, T.J.3
  • 16
    • 0026547507 scopus 로고
    • Electron-microscopic localization of type II,IX and V collagen in the organ of corti
    • Slepecky, N.B., Savage, S.E., Cerafatti, L.K. & Yoo, T.J. Electron-microscopic localization of type II,IX and V collagen in the organ of Corti. Cell Tissue Res. 267, 413-418 (1992).
    • (1992) Cell Tissue Res. , vol.267 , pp. 413-418
    • Slepecky, N.B.1    Savage, S.E.2    Cerafatti, L.K.3    Yoo, T.J.4
  • 17
    • 0023895565 scopus 로고
    • Tectorial membrane. I: Static mechanical properties in vivo
    • Zwislocki, J.J., Chamberlain, S.C. & Slepecky, N.B. Tectorial membrane. I: static mechanical properties in vivo. Hearing Res. 33, 207-222 (1988).
    • (1988) Hearing Res. , vol.33 , pp. 207-222
    • Zwislocki, J.J.1    Chamberlain, S.C.2    Slepecky, N.B.3
  • 18
    • 0028226978 scopus 로고
    • Tightly linked flanking microsatellite markers for the usher syndrome type I locus on the short arm of chromosome 11
    • Keats, B.J., Noury, N., Pelias, M.Z., Deininger, P.L. & Litt, M. Tightly linked flanking microsatellite markers for the Usher syndrome type I locus on the short arm of chromosome 11. Am. J. Hum. Genet. 54, 681-686 (1994).
    • (1994) Am. J. Hum. Genet. , vol.54 , pp. 681-686
    • Keats, B.J.1    Noury, N.2    Pelias, M.Z.3    Deininger, P.L.4    Litt, M.5
  • 19
    • 0032104235 scopus 로고    scopus 로고
    • A gene responsible for nonsyndromic sensorineural deafness (DFNB18) maps to the chromosomal region 11p14-p15.1 containing the Usher syndrome type 1C gene
    • Jain, P.K. et al. A gene responsible for nonsyndromic sensorineural deafness (DFNB18) maps to the chromosomal region 11p14-p15.1 containing the Usher syndrome type 1C gene. Genomics 50, 290-292 (1998).
    • (1998) Genomics , vol.50 , pp. 290-292
    • Jain, P.K.1
  • 20
    • 0032811509 scopus 로고    scopus 로고
    • Mapping of the otogelin gene (OTGN) to mouse chromosome 7 and human chromosome 11p14.3: A candidate for human autosomal recessive nonsyndromic deafness DFNB18
    • Cohen-Salmon, M., Mattei, M.-G. & Petit, C. Mapping of the otogelin gene (OTGN) to mouse chromosome 7 and human chromosome 11p14.3: a candidate for human autosomal recessive nonsyndromic deafness DFNB18. Mamm. Genome 10, 520-522 (1999).
    • (1999) Mamm. Genome , vol.10 , pp. 520-522
    • Cohen-Salmon, M.1    Mattei, M.-G.2    Petit, C.3
  • 21
    • 0031007349 scopus 로고    scopus 로고
    • Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
    • Kelsell, D.P. et al. Connexin 26 mutations in hereditary non-syndromic sensorineural deafness. Nature 387, 80-83 (1997).
    • (1997) Nature , vol.387 , pp. 80-83
    • Kelsell, D.P.1
  • 22
    • 17344373747 scopus 로고    scopus 로고
    • Mutations in the gene encoding gap junction protein β-3 associated with autosomal dominant hearing impairment
    • Xia, J.-h. et al. Mutations in the gene encoding gap junction protein β-3 associated with autosomal dominant hearing impairment. Nature Genet. 20, 370-373 (1998).
    • (1998) Nature Genet. , vol.20 , pp. 370-373
    • Xia, J.-H.1
  • 23
    • 0033524936 scopus 로고    scopus 로고
    • KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness
    • Kubisch, C. et al. KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. Cell 96, 437-446 (1999).
    • (1999) Cell , vol.96 , pp. 437-446
    • Kubisch, C.1
  • 24
    • 85069240579 scopus 로고    scopus 로고
    • Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus
    • Grifa, A. et al. Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus Nature Genet. 23, 16-18 (1999).
    • (1999) Nature Genet. , vol.23 , pp. 16-18
    • Grifa, A.1
  • 25
    • 0029450413 scopus 로고
    • Disruption of murine Hexa gene leads to enzymatic deficiency and to neuronal lysosomal storage, similar to that observed in Tay-Sachs disease
    • Cohen-Tannoudji, M. et al. Disruption of murine Hexa gene leads to enzymatic deficiency and to neuronal lysosomal storage, similar to that observed in Tay-Sachs disease. Mamm. Genome 6, 844-849 (1995).
    • (1995) Mamm. Genome , vol.6 , pp. 844-849
    • Cohen-Tannoudji, M.1
  • 26
    • 0033582330 scopus 로고    scopus 로고
    • Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals
    • Verpy, E., Leibovici, M. & Petit, C. Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals. Proc. Natl Acad. Sci. USA 96, 529-534 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 529-534
    • Verpy, E.1    Leibovici, M.2    Petit, C.3
  • 27
    • 0029845831 scopus 로고    scopus 로고
    • lacZ mouse embryos
    • lacZ mouse embryos. Development 122, 3023-3033 (1996).
    • (1996) Development , vol.122 , pp. 3023-3033
    • Bernex, F.1
  • 29
    • 0001633148 scopus 로고    scopus 로고
    • Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses
    • Zheng, Q.Y., Johnson, K.R. & Reway, L.C. Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses. Hearing Res. 130, 94-107 (1999).
    • (1999) Hearing Res. , vol.130 , pp. 94-107
    • Zheng, Q.Y.1    Johnson, K.R.2    Reway, L.C.3
  • 30
    • 0027392717 scopus 로고
    • Genetics of age-related hearing loss in mice: I. Inbred and F1 hybrid strains
    • Erway, L.C., Willott, J.F., Archer, J.R. & Harrison, D.E. Genetics of age-related hearing loss in mice: I. Inbred and F1 hybrid strains. Hearing Res. 65, 125-132 (1993).
    • (1993) Hearing Res. , vol.65 , pp. 125-132
    • Erway, L.C.1    Willott, J.F.2    Archer, J.R.3    Harrison, D.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.