Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13142-13154

  Novgorodov, Sergei A ^b   Riley, Christopher L ^a   Yu, Jin ^b   Borg, Keith T ^b   Hannun, Yusuf A ^b   Proia, Richard L ^c   Kindy, Mark S ^b   Gudz, Tatyana I ^b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ENZYME ACTIVITY; GENE EXPRESSION; MITOCHONDRIA; PHOSPHOLIPIDS; SPHINGOSINES;

CELLULAR MECHANISMS; IMMUNOPRECIPITATIONS; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL ELECTRON TRANSPORT CHAIN; RATE-LIMITING ENZYMES; SPHINGOLIPID METABOLISM; SPHINGOSINE KINASE 2; TRAUMATIC BRAIN INJURIES;

BRAIN;

CYTOCHROME C OXIDASE; NEUTRAL CERAMIDASE; SPHINGOSINE KINASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT; ENZYME ACTIVATION; GENE EXPRESSION; GENE SILENCING; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; TRANSLATION REGULATION; TRAUMATIC BRAIN INJURY; UPREGULATION;

BRAIN; CELL DEATH; MITOCHONDRIA; RESPIRATORY CHAIN; SPHINGOLIPID;

ALKALINE CERAMIDASE; ANIMALS; BRAIN; BRAIN INJURIES; ELECTRON TRANSPORT COMPLEX IV; HUMANS; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NERVE TISSUE PROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SPHINGOSINE;

EID: 84900398503     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.530311     Document Type: Article

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