The effect of injury severity on behavior: A phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice

Journal of Neurotrauma

Volumn 29, Issue 13, 2012, Pages 2283-2296

  Washington, Patricia M ^a   Forcelli, Patrick A ^a   Wilkins, Tiffany ^a   Zapple, David N ^a   Parsadanian, Maia ^a   Burns, Mark P ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

elevated plus maze; forced swim test; Morris water maze; prepulse inhibition; traumatic brain injury

Indexed keywords

ARTICLE; BEHAVIOR; COGNITIVE DEFECT; COHORT ANALYSIS; COMORBIDITY; CONTROLLED CORTICAL IMPACT INJURY; CONTROLLED STUDY; EMOTIONAL DISORDER; FORCED SWIMMING TEST; INJURY SEVERITY; MALE; MAZE TEST; MOUSE; NONHUMAN; PHENOTYPE; PREPULSE INHIBITION; STARTLE REFLEX; TRAUMATIC BRAIN INJURY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN INJURIES; CEREBRAL CORTEX; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; MALE; MENTAL DISORDERS; MICE; MICE, INBRED C57BL; PHENOTYPE; TRAUMA SEVERITY INDICES;

EID: 84865616019     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2012.2456     Document Type: Article

References (39)

1. Arciniegas, D., Adler, L., Topkoff, J., Cawthra, E., Filley, C. M., and Reite, M. (1999). Attention and memory dysfunction after traumatic brain injury: cholinergic mechanisms, sensory gating, and a hypothesis for further investigation. Brain Inj. 13, 1-13. (Pubitemid 29043314)
2. Arciniegas, D., Olincy, A., Topkoff, J., McRae, K., Cawthra, E., Filley, C. M., Reite, M., and Adler, L. E. (2000). Impaired auditory gating and P50 nonsuppression following traumatic brain injury. J. Neuropsychiatry Clin. Neurosci. 12, 77-85. (Pubitemid 30093693)
3. Bhardwaj, S. K., Forcelli, P. A., Palchik, G., Gale, K., Srivastava, L. K., and Kondratyev, A. (2012). Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology 62, 2336-2344.
4. Bombardier, C. H., Fann, J. R., Temkin, N. R., Esselman, P. C., Barber, J., and Dikmen, S. S. (2010). Rates of major depressive disorder and clinical outcomes following traumatic brain injury. JAMA 303, 1938-1945.
5. Borlongan, C. V., and Sanberg, P. R. (1995). Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamineinduced hemiparkinsonism. J. Neurosci. 15, 5372-5378.
6. Chauhan, N. B., Gatto, R., and Chauhan, M. B. (2010). Neuroanatomical correlation of behavioral deficits in the CCI model of TBI. J. Neurosci. Methods 190, 1-9.
7. Draper, K., and Ponsford, J. (2009). Long-term outcome following traumatic brain injury: a comparison of subjective reports by those injured and their relatives. Neuropsychol. Rehabil. 19, 645-661.
8. Forcelli, P. A., and Heinrichs, S. C. (2008). Teratogenic effects of maternal antidepressant exposure on neural substrates of drug-seeking behavior in offspring. Addict Biol. 13, 52-62. (Pubitemid 351202131)
9. Forcelli, P. A., Kozlowski, R., Snyder, C., Kondratyev, A., and Gale, K. (2012b). Effects of neonatal antiepileptic drug exposure on cognitive, emotional, and motor function in adult rats. J. Pharmacol. Exp. Ther. 340, 558-566.
10. Forcelli, P. A., West, E. A., Murnen, A. T., and Malkova, L. (2012a). Ventral pallidum mediates amygdala-evoked deficits in prepulse inhibition. Behav. Neurosci. 126, 290-300.
11. Fox, G. B., Levasseur, R. A., and Faden, A. I. (1999). Behavioral responses of C57BL/6, FVB/N, and 129/SvEMS mouse strains to traumatic brain injury: implications for gene targeting approaches to neurotrauma. J. Neurotrauma 16, 377-389. (Pubitemid 29264790)
12. Gould, K. R., Ponsford, J. L., Johnston, L., and Schonberger, M. (2011). The nature, frequency and course of psychiatric disorders in the first year after traumatic brain injury: a prospective study. Psychol. Med. 41, 2099-2109.
13. Hamm, R. J., Dixon, C. E., Gbadebo, D. M., Singha, A. K., Jenkins, L. W., Lyeth, B. G., and Hayes, R. L. (1992). Cognitive deficits following traumatic brain injury produced by controlled cortical impact. J. Neurotrauma 9, 11-20.
14. Harkin, A., Connor, T. J., Burns, M. P., and Kelly, J. P. (2004). Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. Eur. Neuropsychopharmacol. 14, 274-281. (Pubitemid 38649083)
15. Hogg, S., Moser, P. C., and Sanger, D. J. (1998). Mild traumatic lesion of the right parietal cortex of the rat: selective behavioural deficits in the absence of neurological impairment. Behavioural Brain Res. 93, 143-155. (Pubitemid 28289433)
16. Jamora, C. W., Young, A., and Ruff, R. M. (2012). Comparison of subjective cognitive complaints with neuropsychological tests in individuals with mild vs. more severe traumatic brain injuries. Brain Inj. 26, 36-47.
17. Jones, N. C., Cardamone, L., Williams, J. P., Salzberg, M. R., Myers, D., and O'Brien, T. J. (2008). Experimental traumatic brain injury induces a pervasive hyperanxious phenotype in rats. J. Neurotrauma 25, 1367-1374.
18. Jorge, R. E., Robinson, R. G., Moser, D., Tateno, A., Crespo-Facorro, B., and Arndt, S. (2004). Major depression following traumatic brain injury. Arch. Gen. Psychiatry 61, 42-50. (Pubitemid 38044640)
19. Levin, H. S., High, W. M., Goethe, K. E., Sisson, R. A., Overall, J. E., Rhoades, H. M., Eisenberg, H. M., Kalisky, Z., and Gary, H. E. (1987). The neurobehavioural rating scale: assessment of the behavioural sequelae of head injury by the clinician. J. Neurol. Neurosurg. Psychiatry 50, 183-193. (Pubitemid 17016559)
20. Liu, Y. R., Cardamone, L., Hogan, R. E., Gregoire, M. C., Williams, J. P., Hicks, R. J., Binns, D., Koe, A., Jones, N. C., Myers, D. E., O'Brien, T. J., and Bouilleret, V. (2010). Progressive metabolic and structural cerebral perturbations after traumatic brain injury: an in vivo imaging study in the rat. J. Nucl. Med. 51, 1788-1795.
21. Loane, D. J., Pocivavsek, A., Moussa, C. E., Thompson, R., Matsuoka, Y., Faden, A. I., Rebeck, G. W., and Burns, M. P. (2009). Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat. Med. 15, 377-379.
22. Markgraf, C. G., Clifton, G. L., Aguirre, M., Chaney, S. F., Knox-Du Bois, C., Kennon, K., and Verma, N. (2001). Injury severity and sensitivity to treatment after controlled cortical impact in rats. J. Neurotrauma 18, 175-186. (Pubitemid 32173425)
23. Milman, A., Rosenberg, A., Weizman, R., and Pick, C. G. (2005). Mild traumatic brain injury induces persistent cognitive deficits and behavioral disturbances in mice. J. Neurotrauma 22, 1003-1010. (Pubitemid 41362066)
24. Milman, A., Zohar, O., Maayan, R., Weizman, R., and Pick, C. G. (2008). DHEAS repeated treatment improves cognitive and behavioral deficits after mild traumatic brain injury. Eur. Neuropsychopharmacol. 18, 181-187.
25. Newcomb, J. K., Zhao, X., Pike, B. R., and Hayes, R. L. (1999). Temporal profile of apoptotic-like changes in neurons and astrocytes following controlled cortical impact injury in the rat. Exp. Neurol. 158, 76-88. (Pubitemid 29344319)
26. Olmos-Serrano, J. L., Corbin, J. G., and Burns, M. P. (2011). The GABA (A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome. Dev. Neurosci. 33, 395-403.
27. Pandey, D. K., Yadav, S. K., Mahesh, R., and Rajkumar, R. (2009). Depression-like and anxiety-like behavioural aftermaths of impact accelerated traumatic brain injury in rats: a model of comorbid depression and anxiety? Behav. Brain Res. 205, 436-442.
28. Pellow, S., Chopin, P., File, S. E., and Briley, M. (1985). Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods 14, 149-167. (Pubitemid 16239568)
29. Petullo, D., Masonic, K., Lincoln, C., Wibberley, L., Teliska, M., and Yao, D. L. (1999). Model development and behavioral assessment of focal cerebral ischemia in rats. Life Sci. 64, 1099-1108. (Pubitemid 29152027)
30. Rapoport, M., McCauley, S., Levin, H., Song, J., and Feinstein, A. (2002). The role of injury severity in neurobehavioral outcome 3 months after traumatic brain injury. Neuropsychiatry Neuropsychol. Behav. Neurol. 15, 123-132. (Pubitemid 34625863)
31. Satz, P., Zaucha, K., Forney, D. L., McCleary, C., Asarnow, R. F., Lightm R., Levin, H., Kelly, D., Bergsneider, M., Hovda, D., Martin, N., Caron, M. J., Namerow, N., and Becker, D. (1998). Neuropsychological, psychosocial and vocational correlates of the Glasgow Outcome Scale at 6 months post-injury: a study of moderate to severe traumatic brain injury patients. Brain Inj. 12, 555-567. (Pubitemid 28302004)
32. Scheff, S. W., Baldwin, S. A., Brown, R. W., and Kraemer, P. J. (1997). Morris water maze deficits in rats following traumatic brain injury: lateral controlled cortical impact. J. Neurotrauma 14, 615-627. (Pubitemid 27424265)
33. Schwarzbold, M. L., Rial, D., De Bem, T., Machado, D. G., Cunha, M. P., dos Santos, A. A., dos Santos, D. B., Figueiredo, C. P., Farina, M., Goldfeder, E. M., Rodrigues, A. L., Prediger, R. D., and Walz, R. (2010). Effects of traumatic brain injury of different severities on emotional, cognitive, and oxidative stressrelated parameters in mice. J. Neurotrauma 27, 1883-1893.
34. Shapira, M., Licht, A., Milman, A., Pick, C. G., Shohami, E., and Eldar-Finkelman, H. (2007). Role of glycogen synthase kinase-3beta in early depressive behavior induced by mild traumatic brain injury. Mol. Cell Neurosci. 34, 571-577. (Pubitemid 46483079)
35. Smith, D. H., Okiyama, K., Thomas, M. J., Claussen, B., and McIntosh, T. K. (1991). Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. J. Neurotrauma 8, 259-269.
36. Walf, A. A., and Frye, C. A. (2007). The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nat. Protoc. 2, 322-328. (Pubitemid 47040046)
37. Wiley, J. L., Compton, A. D., Pike, B. R., Temple, M. D., McElderry, J. W., and Hamm, R. J. (1996). Reduced sensorimotor reactivity following traumatic brain injury in rats. Brain Res. 716, 47-52. (Pubitemid 26155219)
38. Wobbrock, J. O., Findlater, L., Gergle, D., and Higgins, J. J. (2011). The aligned rank transform for nonparametric analysis of multiple factors using only ANOVA procedures. Proc. ACM Conf. Human Factors Computing Systems (CHI 11), 4.
39. Zohar, O., Rubovitch, V., Milman, A., Schreiber, S., and Pick, C. G. (2011). Behavioral consequences of minimal traumatic brain injury in mice. Acta Neurobiol. Exp. (Wars.) 71, 36-45.