Schisandra chinensis peptidoglycan-assisted transmembrane transport of lignans uniquely altered the pharmacokinetic and pharmacodynamic mechanisms in human HepG2 cell model

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Chyau, Charng Cherng ^a   Ker, Yaw Bee ^a   Chang, Chi Huang ^a   Huang, Shiau Huei ^a   Wang, Hui Er ^a   Peng, Chiung Chi ^b   Peng, Robert Y ^a,b  

^a HUNGKUANG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ESSENTIAL AMINO ACID; GOMISIN; LIGNAN; MONOSACCHARIDE; PEPTIDOGLYCAN; SC 2; SCHIZANDRIN A; SCHIZANDRIN B; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ARTICLE; CELL TRANSPORT; CELL VIABILITY; CHEMICAL LABELING; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG TRANSPORT; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE ANALYSIS; FOURIER TRANSFORMATION; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; LIVER PROTECTION; NONHUMAN; PROTEIN PURIFICATION; SCHISANDRA CHINENSIS; THERMODYNAMICS;

ANALYSIS OF VARIANCE; BIOLOGICAL TRANSPORT; FRUIT; HEP G2 CELLS; HUMANS; IN SITU NICK-END LABELING; LIGNANS; MEMBRANE TRANSPORT MODULATORS; PEPTIDOGLYCAN; PLANT EXTRACTS; SCHISANDRA; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TETRAZOLIUM SALTS; THIAZOLES; X-RAY DIFFRACTION;

EID: 84900302255     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085165     Document Type: Article

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