Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

Human Molecular Genetics

Volumn 23, Issue 11, 2014, Pages 2816-2833

  Kong, Stephanie M Y ^a,g   Chan, Brian K K ^a   Park, Jin Sung ^c   Hill, Kathryn J ^a   Aitken, Jade B ^d,e,f   Cottle, Louise ^a   Farghaian, Hovik ^a   Cole, Adam R ^a   Lay, Peter A ^d   Sue, Carolyn M ^c   Cooper, Antony A ^a,b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ROYAL NORTH SHORE HOSPITAL   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e AUSTRALIAN SYNCHROTRON   (Australia)

^f INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^g VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; PARK9 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; ZINC; ATP13A2 PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ARTICLE; BIOGENESIS; CONTROLLED STUDY; EXOSOME; HOMEOSTASIS; HUMAN; HUMAN CELL; LYSOSOME; MULTIVESICULAR BODY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN TRANSPORT; SUBSTANTIA NIGRA PARS COMPACTA; AUTOPHAGY; ENZYMOLOGY; GENETICS; METABOLISM; NERVE CELL;

ALPHA-SYNUCLEIN; AUTOPHAGY; EXOSOMES; HOMEOSTASIS; HUMANS; NEURONS; PARKINSON DISEASE; PROTON-TRANSLOCATING ATPASES; ZINC;

EID: 84899964982     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu099     Document Type: Article

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