A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice

Molecular and Cellular Biology

Volumn 34, Issue 11, 2014, Pages 2029-2045

  Cecchini, Matthew J ^a   Thwaites, Michael J ^a   Talluri, Srikanth ^a   MacDonald, James I ^a   Passos, Daniel T ^a   Chong, Jean Leon ^b   Cantalupo, Paul ^c   Stafford, Paul M ^a   Sáenz Robles, M Teresa ^c   Francis, Sarah M ^a   Pipas, James M ^c   Leone, Gustavo ^b   Welch, Ian ^a   Dick, Frederick A ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; EMBRYO; FIBROBLAST; GAMMA IRRADIATION; GENE MUTATION; GENE TARGETING; LIFESPAN; MOUSE; MUSCLE ATROPHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSACTIVATION; WILD TYPE;

ADENOCARCINOMA; ALLELES; ANIMALS; BINDING SITES; CELL LINE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; E2F TRANSCRIPTION FACTORS; FIBROBLASTS; GENE TARGETING; MICE; MICE, KNOCKOUT; MUTATION; PITUITARY NEOPLASMS; RETINOBLASTOMA PROTEIN; S PHASE; S PHASE CELL CYCLE CHECKPOINTS;

EID: 84899888987     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01589-13     Document Type: Article

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