5′-O-Methylphosphonate nucleic acids - New modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes

Nucleic Acids Research

Volumn 42, Issue 8, 2014, Pages 5378-5389

  Šǐpová, Hana ^a   Špringer, Tomáš ^a   Rejman, Dominik ^b   Šimák, Ondřej ^b   Petrová, Magdalena ^b   Novák, Pavel ^b   Rosenbergová, Šárka ^b   Páv, Ondřej ^b   Liboska, Radek ^b   Barvík, Ivan ^c   Štěpánek, Josef ^c   Rosenberg, Ivan ^b   Homola, Jiří ^a  

^a INSTITUTE OF PHOTONICS AND ELECTRONICS   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

5' O METHYLPHOSPHONATE NUCLEIC ACID; ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; MICRORNA; MICRORNA 191; NUCLEIC ACID; RIBONUCLEASE H; UNCLASSIFIED DRUG; PHOSPHONIC ACID DERIVATIVE;

ARTICLE; BIOSENSOR; COMPLEX FORMATION; CONTROLLED STUDY; DNA MODIFICATION; ENZYME ACTIVITY; ENZYME MECHANISM; ESCHERICHIA COLI; MOLECULAR INTERACTION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RNA ANALYSIS; RNA CLEAVAGE; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; THERMOSTABILITY; CHEMISTRY; ENZYMOLOGY; METABOLISM;

ESCHERICHIA COLI; MICRORNAS; OLIGONUCLEOTIDES, ANTISENSE; ORGANOPHOSPHONATES; RIBONUCLEASE H; RNA CLEAVAGE;

EID: 84899878958     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku125     Document Type: Article

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