-
1
-
-
0029856329
-
Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
-
DOI 10.1023/A:1016026101195
-
Zelphati, O and Szoka, FC Jr (1996). Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids. Pharm Res 13: 1367-1372. (Pubitemid 26344983)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.9
, pp. 1367-1372
-
-
Zelphati, O.1
Szoka Jr., F.C.2
-
2
-
-
20444377785
-
Polyethylenimine-based non-viral gene delivery systems
-
DOI 10.1016/j.ejpb.2004.11.011, PII S0939641105000147
-
Lungwitz, U, Breunig, M, Blunk, T and Göpferich, A (2005). Polyethylenimine-based nonviral gene delivery systems. Eur J Pharm Biopharm 60: 247-266. (Pubitemid 40804565)
-
(2005)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.60
, Issue.2
, pp. 247-266
-
-
Lungwitz, U.1
Breunig, M.2
Blunk, T.3
Gopferich, A.4
-
3
-
-
33746438424
-
Toxicity of cationic lipids and cationic polymers in gene delivery
-
DOI 10.1016/j.jconrel.2006.04.014, PII S0168365906002045
-
Lv, H, Zhang, S, Wang, B, Cui, S and Yan, J (2006). Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 114: 100-109. (Pubitemid 44128621)
-
(2006)
Journal of Controlled Release
, vol.114
, Issue.1
, pp. 100-109
-
-
Lv, H.1
Zhang, S.2
Wang, B.3
Cui, S.4
Yan, J.5
-
4
-
-
78650054331
-
Drug delivery trends in clinical trials and translational medicine: Challenges and opportunities in the delivery of nucleic acid-based therapeutics
-
Xu, L and Anchordoquy, T (2011). Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics. J Pharm Sci 100: 38-52.
-
(2011)
J Pharm Sci
, vol.100
, pp. 38-52
-
-
Xu, L.1
Anchordoquy, T.2
-
5
-
-
75649138331
-
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides unassisted by transfection reagents
-
Stein, CA, Hansen, B, Lai, J, Wu, S, Voskresenskiy, A, Hoeg, A et al. (2009) Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides unassisted by transfection reagents. Nucl Acids Res.
-
(2009)
Nucl Acids Res
-
-
Stein, C.A.1
Hansen, B.2
Lai, J.3
Wu, S.4
Voskresenskiy, A.5
Hoeg, A.6
-
6
-
-
79953767743
-
Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection
-
Zhang, Y, Qu, Z, Kim, S, Shi, V, Liao, B, Kraft, P et al. (2011). Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection. Gene Ther 18: 326-333.
-
(2011)
Gene Ther
, vol.18
, pp. 326-333
-
-
Zhang, Y.1
Qu, Z.2
Kim, S.3
Shi, V.4
Liao, B.5
Kraft, P.6
-
7
-
-
84555187851
-
Silencing of gene expression by gymnotic delivery of antisense oligonucleotides
-
Soifer, HS, Koch, T, Lai, J, Hansen, B, Hoeg, A, Oerum, H et al. (2012). Silencing of gene expression by gymnotic delivery of antisense oligonucleotides. Methods Mol Biol 815: 333-346.
-
(2012)
Methods Mol Biol
, vol.815
, pp. 333-346
-
-
Soifer, H.S.1
Koch, T.2
Lai, J.3
Hansen, B.4
Hoeg, A.5
Oerum, H.6
-
8
-
-
0343065617
-
LNA (locked nucleic acids): Synthesis and high-affinity nucleic acid recognition
-
Singh, S, Nielsen, P, Koshkin, A and Wengel, J (1998). LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition. Chem Commun 455-456. (Pubitemid 128675297)
-
(1998)
Chemical Communications
, Issue.4
, pp. 455-456
-
-
Singh, S.K.1
Nielsen, P.2
Koshkin, A.A.3
Wengel, J.4
-
9
-
-
65249165824
-
Locked nucleic acid: Properties and therapeutic aspects
-
Kurreck, J (ed), RSC Publishing, Cambridge
-
Koch, T, Rosenbohm, C, Hansen, H, Hansen, B, Straarup, E and Kauppinen, S. (2008). Locked Nucleic Acid: Properties and Therapeutic Aspects. In Kurreck, J (ed), Therapeutic Oligonucleotides. RSC Publishing, Cambridge, pp. 103-134.
-
(2008)
Therapeutic Oligonucleotides
, pp. 103-134
-
-
Koch, T.1
Rosenbohm, C.2
Hansen, H.3
Hansen, B.4
Straarup, E.5
Kauppinen, S.6
-
10
-
-
0032539186
-
Hybrids of RNA and arabinonucleic acids (ANA and 2'F-ANA) are substrates of ribonuclease H [11]
-
DOI 10.1021/ja982325+
-
Damha, MJ, Wilds, CJ, Noronha, A, Brukner, I, Borkow, G and Parniak MA (1998). Hybrids of RNA and arabinonucleic acids (ANA and 2'F-ANA are substrates of ribonuclease H. J Amer Chem Soc 121:12976-12977. (Pubitemid 29013857)
-
(1998)
Journal of the American Chemical Society
, vol.120
, Issue.49
, pp. 12976-12977
-
-
Damha, M.J.1
Wilds, C.J.2
Noronha, A.3
Brukner, I.4
Borkow, G.5
Arion, D.6
Parniak, M.A.7
-
11
-
-
46249131334
-
2'-Fluoroarabinonucleic acids (2'F-ANA): History, properties and new frontiers
-
Watts, J and Damha, MJ. (2008) 2'-Fluoroarabinonucleic acids (2'F-ANA): history, properties and new frontiers. Can J Chem 86:641-656.
-
(2008)
Can J Chem
, vol.86
, pp. 641-656
-
-
Watts, J.1
Damha, M.J.2
-
12
-
-
0037066105
-
Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2′-deoxy-2′-fluoro-D-arabinose and 2′-deoxyribose nucleotides
-
DOI 10.1021/bi0115075
-
Lok, CN, Viazovkina, E, Min, KL, Nagy, E, Wilds, CJ, Damha, MJ et al. (2002). Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-d-arabinose and 2'-deoxyribose nucleotides. Biochemistry 41: 3457-3467. (Pubitemid 34214044)
-
(2002)
Biochemistry
, vol.41
, Issue.10
, pp. 3457-3467
-
-
Lok, C.-N.1
Viazovkina, E.2
Min, K.-L.3
Nagy, E.4
Wilds, C.J.5
Damha, M.J.6
Parniak, M.A.7
-
13
-
-
32644436335
-
2′-Deoxy-2′-fluoro-β-D-arabinonucleic acid (2′F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing
-
DOI 10.1093/nar/gkj455
-
Kalota, A, Karabon, L, Swider, CR, Viazovkina, E, Elzagheid, M, Damha, MJ et al. (2006). 2'-deoxy-2'-fluoro-beta-d-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing. Nucleic Acids Res 34: 451-461. (Pubitemid 43240235)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.2
, pp. 451-461
-
-
Kalota, A.1
Karabon, L.2
Swider, C.R.3
Viazovkina, E.4
Elzagheid, M.5
Damha, M.J.6
Gewirtz, A.M.7
-
14
-
-
64549086726
-
Studies on the hydrolytic stability of 2'-fluoroarabinonucleic acid (2'F-ANA)
-
Watts, JK, Katolik, A, Viladoms, J and Damha, MJ (2009). Studies on the hydrolytic stability of 2'-fluoroarabinonucleic acid (2'F-ANA). Org Biomol Chem 7: 1904-1910.
-
(2009)
Org Biomol Chem
, vol.7
, pp. 1904-1910
-
-
Watts, J.K.1
Katolik, A.2
Viladoms, J.3
Damha, M.J.4
-
15
-
-
0034666192
-
2'-Deoxy-2'-fluoro-beta-d-arabinonucleosides and oligonucleotides (2'F-ANA): Synthesis and physicochemical studies
-
Wilds, CJ and Damha, MJ (2000). 2'-Deoxy-2'-fluoro-beta-d- arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies. Nucleic Acids Res 28: 3625-3635.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 3625-3635
-
-
Wilds, C.J.1
Damha, M.J.2
-
16
-
-
33644675811
-
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
-
DOI 10.1200/JCO.2005.03.4777
-
Scher, HI and Sawyers, CL (2005). Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol 23: 8253-8261. (Pubitemid 46211563)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.32
, pp. 8253-8261
-
-
Scher, H.I.1
Sawyers, C.L.2
-
17
-
-
84863011652
-
Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells
-
Soifer, HS, Souleimanian, N, Wu, S, Voskresenskiy, AM, Collak, FK, Cinar, B et al. (2012). Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells. J Biol Chem 287: 3777-3787.
-
(2012)
J Biol Chem
, vol.287
, pp. 3777-3787
-
-
Soifer, H.S.1
Souleimanian, N.2
Wu, S.3
Voskresenskiy, A.M.4
Collak, F.K.5
Cinar, B.6
-
18
-
-
85047697645
-
Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor
-
DOI 10.1038/sj/cgt/7700416
-
Eder, IE, Hoffmann, J, Rogatsch, H, Schäfer, G, Zopf, D, Bartsch, G et al. (2002). Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor. Cancer Gene Ther 9: 117-125. (Pubitemid 34141913)
-
(2002)
Cancer Gene Therapy
, vol.9
, Issue.2
, pp. 117-125
-
-
Eder, I.E.1
Hoffmann, J.2
Rogatsch, H.3
Schafer, G.4
Zopf, D.5
Bartsch, G.6
Klocker, H.7
-
19
-
-
0032973996
-
ω-6 Polyunsaturated fatty acid-stimulated cellular internalization of phosphorothioate oligodeoxynucleotides. Evidence for protein kinase C-ζ dependency
-
DOI 10.1016/S0006-2952(99)00126-4, PII S0006295299001264
-
Khaled, Z, Ho, YY, Benimetskaya, L, Deckelbaum, RJ and Stein, CA (1999). Omega-6 polyunsaturated fatty acid-stimulated cellular internalization of phosphorothioate oligodeoxynucleotides: evidence for protein kinase C-zeta dependency. Biochem Pharmacol 58: 411-423. (Pubitemid 29281540)
-
(1999)
Biochemical Pharmacology
, vol.58
, Issue.3
, pp. 411-423
-
-
Khaled, Z.1
Ho, Y.-Y.2
Benimetskaya, L.3
Deckelbaum, R.J.4
Stein, C.A.5
-
20
-
-
0033153374
-
Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes
-
DOI 10.1093/nar/27.11.2315
-
Laktionov, PP, Dazard, JE, Vives, E, Rykova, EY, Piette, J, Vlassov, VV et al. (1999). Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes. Nucleic Acids Res 27: 2315-2324. (Pubitemid 29245650)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.11
, pp. 2315-2324
-
-
Laktionov, P.P.1
Dazard, J.-E.2
Vives, E.3
Rykova, E.Y.4
Piette, J.5
Vlassov, V.V.6
Lebleu, B.7
-
21
-
-
0000407290
-
Mechanism of oligonucleotide uptake by cells: Involvement of specific receptors?
-
Yakubov, LA, Deeva, EA, Zarytova, VF, Ivanova, EM, Ryte, AS, Yurchenko, LV et al. (1989). Mechanism of oligonucleotide uptake by cells: involvement of specific receptors? Proc Natl Acad Sci USA 86: 6454-6458. (Pubitemid 19236298)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.17
, pp. 6454-6458
-
-
Yakubov, L.A.1
Deeva, E.A.2
Zarytova, V.F.3
Ivanova, E.M.4
Ryte, A.S.5
Yurchenko, L.V.6
Vlassov, V.V.7
-
22
-
-
0034601112
-
Cellular delivery of antisense oligonucleotides
-
DOI 10.1016/S0939-6411(00)00088-6, PII S0939641100000886
-
Lebedeva, I, Benimetskaya, L, Stein, CA and Vilenchik, M (2000). Cellular delivery of antisense oligonucleotides. Eur J Pharm Biopharm 50: 101-119. (Pubitemid 30326691)
-
(2000)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.50
, Issue.1
, pp. 101-119
-
-
Lebedeva, I.1
Benimetskaya, L.2
Stein, C.A.3
Vilenchik, M.4
-
23
-
-
0002971147
-
Pharmacokinetics of oligonucleotides: A review of current knowledge and issues for the future
-
Stein, C and Krieg, A. (eds.), Wiley-Liss, NY
-
Wallace, T, Cossum, P and Cameron, P. (1998). Pharmacokinetics of oligonucleotides: A review of current knowledge and issues for the future. In Stein, C and Krieg, A. (eds.) Applied Antisense Oligonucleotide Technology. Wiley-Liss, NY, pp. 407-429.
-
(1998)
Applied Antisense Oligonucleotide Technology.
, pp. 407-429
-
-
Wallace, T.1
Cossum, P.2
Cameron, P.3
-
24
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
DOI 10.1038/nature04871, PII NATURE04871
-
Pouysségur, J, Dayan, F and Mazure, NM (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441: 437-443. (Pubitemid 44050138)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
25
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
DOI 10.1126/science.1104819
-
Jain, RK (2005). Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307: 58-62. (Pubitemid 40093472)
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
26
-
-
0032781920
-
Understanding barriers to drug delivery: High resolution in vivo imaging is key
-
Jain, RK (1999). Understanding barriers to drug delivery: high resolution in vivo imaging is key. Clin Cancer Res 5: 1605-1606. (Pubitemid 29334434)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.7
, pp. 1605-1606
-
-
Jain, R.K.1
-
27
-
-
84862211680
-
The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity
-
Felber, AE, Bayó-Puxan, N, Deleavey, GF, Castagner, B, Damha, MJ and Leroux, JC (2012). The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity. Biomaterials 33: 5955-5965.
-
(2012)
Biomaterials
, vol.33
, pp. 5955-5965
-
-
Felber, A.E.1
Bayó-Puxan, N.2
Deleavey, G.F.3
Castagner, B.4
Damha, M.J.5
Leroux, J.C.6
-
28
-
-
0033058904
-
Selective activation of phospholipase D2 by unsaturated fatty acid
-
DOI 10.1016/S0014-5793(99)00745-0, PII S0014579399007450
-
Kim, JH, Kim, Y, Lee, SD, Lopez, I, Arnold, RS, Lambeth, JD et al. (1999). Selective activation of phospholipase D2 by unsaturated fatty acid. FEBS Lett 454: 42-46. (Pubitemid 29296922)
-
(1999)
FEBS Letters
, vol.454
, Issue.1-2
, pp. 42-46
-
-
Kim, J.H.1
Kim, Y.2
Lee, S.D.3
Lopez, I.4
Arnold, R.S.5
Lambeth, J.D.6
Suh, P.-G.7
Ryu, S.H.8
-
29
-
-
33745828694
-
Src triggers circular ruffling and macropinocytosis at the apical surface of polarized MDCK cells
-
DOI 10.1111/j.1600-0854.2006.00412.x
-
Mettlen, M, Platek, A, Van Der Smissen, P, Carpentier, S, Amyere, M, Lanzetti, L et al. (2006). Src triggers circular ruffling and macropinocytosis at the apical surface of polarized MDCK cells. Traffic 7: 589-603. (Pubitemid 44026756)
-
(2006)
Traffic
, vol.7
, Issue.5
, pp. 589-603
-
-
Mettlen, M.1
Platek, A.2
Van Der Smissen, P.3
Carpentier, S.4
Amyere, M.5
Lanzetti, L.6
De Diesbach, P.7
Tyteca, D.8
Courtoy, P.J.9
-
30
-
-
34547104823
-
Regulation of phospholipase D activity, membrane targeting and intracellular trafficking by phosphoinositides
-
Morris, AJ (2007). Regulation of phospholipase D activity, membrane targeting and intracellular trafficking by phosphoinositides. Biochem Soc Symp : 247-257.
-
(2007)
Biochem Soc Symp
, pp. 247-257
-
-
Morris, A.J.1
-
31
-
-
0025173323
-
A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization
-
Chalifa, V, Möhn, H and Liscovitch, M (1990). A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization. J Biol Chem 265: 17512-17519.
-
(1990)
J Biol Chem
, vol.265
, pp. 17512-17519
-
-
Chalifa, V.1
Möhn, H.2
Liscovitch, M.3
-
32
-
-
0037338677
-
PKC-ζ mediates norepinephrine-induced phospholipase D activation and cell proliferation in VSMC
-
DOI 10.1161/01.HYP.0000047873.76255.0B
-
Parmentier, JH, Smelcer, P, Pavicevic, Z, Basic, E, Idrizovic, A, Estes, A et al. (2003). PKC-zeta mediates norepinephrine-induced phospholipase D activation and cell proliferation in VSMC. Hypertension 41(3 Pt 2): 794-800. (Pubitemid 36314593)
-
(2003)
Hypertension
, vol.41
, Issue.3
, pp. 794-800
-
-
Parmentier, J.-H.1
Smelcer, P.2
Pavicevic, Z.3
Basic, E.4
Idrizovic, A.5
Estes, A.6
Malik, K.U.7
-
33
-
-
0029610065
-
Mammalian phospholipase D: Activation by ammonium sulfate and nucleotides
-
DOI 10.1073/pnas.92.26.12319
-
Nakamura, S, Shimooku, K, Akisue, T, Jinnai, H, Hitomi, T, Kiyohara, Y et al. (1995). Mammalian phospholipase D: activation by ammonium sulfate and nucleotides. Proc Natl Acad Sci USA 92: 12319-12322. (Pubitemid 26014062)
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.26
, pp. 12319-12322
-
-
Nakamura, S.-I.1
Shimooku, K.2
Akisue, T.3
Jinnai, H.4
Hitomi, T.5
Kiyohara, Y.6
Ogino, C.7
Yoshida, K.8
Nishizuka, Y.9
|