Nucleoside 5′-C-phosphonates: reactivity of the α-hydroxyphosphonate moiety

Tetrahedron

Volumn 62, Issue 20, 2006, Pages 4917-4932

  Králíková, Šárka ^a   Buděšínký, Miloš ^a   Masojídková, Milena ^a   Rosenberg, Ivan ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Addition reaction; Nucleophilic substitution; Nucleoside 5 aldehydes; Oxidation; Phosphonates

Indexed keywords

2' DEOXYADENOSIN 5' C YLPHOSPHONIC ACID; 2' DEOXYCYTIDIN 5' C YLPHOSPHONIC ACID; 2' DEOXYGUANOSIN 5' C YLPHOSPHONIC ACID; 2' DEOXYTHYMIDIN 5' C YLPHOSPHONIC ACID; 3 N METHOXYMETHYLURIDIN 5' C YLPHOSPHONIC ACID; 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONIC ACID; ALDEHYDE DERIVATIVE; ALPHA HYDROXYPHOSPHONATE; ANTIVIRUS AGENT; AZIDE; CYTIDIN 5' C YLPHOSPHONIC ACID; CYTOSTATIC AGENT; DIETHYL 3' O BENZYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIETHYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIETHYL 3' O TRIMETHYLACETYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIISOPROPYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIMETHYL 2 N BENZOYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYGUANOSIN 5' C YLPHOSPHONATE; DIMETHYL 2 N ISOBUTYRYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYGUANOSIN 5' C YLPHOSPHONATE; DIMETHYL 3' O BENZYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIMETHYL 3' O DIMETHOXYTRITYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIMETHYL 3' O TERT BUTYLDIMETHYLSILYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIMETHYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYTHYMIDIN 5' C YLPHOSPHONATE; DIMETHYL 4 N BENZOYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYCYTIDIN 5' C YLPHOSPHONATE; DIMETHYL 6 N BENZOYL 2' DEOXYADENOSIN 3' O DIMETHOXYTRITYL 5' C YLPHOSPHONATE; DIMETHYL 6 N BENZOYL 3' O TERT BUTYLDIPHENYLSILYL 2' DEOXYADENOSIN 5' C YLPHOSPHONATE; NUCLEOSIDE; PHOSPHITE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIDIN 5' C YLPHOSPHONIC ACID;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CHIRALITY; CONTROLLED STUDY; CYTOSTASIS; DRUG SYNTHESIS; EPIMER; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

ANIMALIA;

EID: 33646047150     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.03.008     Document Type: Article

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