Complex between Human RNase HI and the phosphonate-DNA/RNA duplex: Molecular dynamics study

Journal of Molecular Graphics and Modelling

Volumn 44, Issue , 2013, Pages 81-90

  Maláč, Kamil ^a   Barvík, Ivan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

ACEMD; Antisense oligonucleotides; Argonaute; Molecular dynamics; Phosphonate; RNAi; RNase H

Indexed keywords

BINS; METAL IONS; METALS; OLIGONUCLEOTIDES;

ACEMD; ANTISENSE OLIGONUCLEOTIDES; ARGONAUTE; PHOSPHONATES; RNAI; RNASE H;

MOLECULAR DYNAMICS;

ARGONAUTE PROTEIN; DNA; MAGNESIUM; MAGNESIUM ION; METAL ION; NUCLEOTIDE; OLIGONUCLEOTIDE; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; RIBONUCLEASE H; RIBONUCLEASE HI; RNA; UNCLASSIFIED DRUG;

ARTICLE; ATOM; ENZYME ACTIVITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SIMULATION; THERMUS THERMOPHILUS;

THERMUS THERMOPHILUS;

ACEMD; ANTISENSE OLIGONUCLEOTIDES; ARGONAUTE; MOLECULAR DYNAMICS; PHOSPHONATE; RNAI; RNASE H;

BINDING SITES; CATALYTIC DOMAIN; DNA; HUMANS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; ORGANOPHOSPHONATES; PROTEIN BINDING; PROTEIN CONFORMATION; RIBONUCLEASE H; RNA;

EID: 84878719458     PISSN: 10933263     EISSN: 18734243     Source Type: Journal    
DOI: 10.1016/j.jmgm.2013.05.004     Document Type: Article

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