Novel isosteric, isopolar phosphonate analogs of oligonucleotides: Preparation and properties

Biopolymers

Volumn 83, Issue 4, 2006, Pages 400-413

  Točík, Zdeněk ^a   Barvík Jr , Ivan ^b   Buděšínský, Miloš ^a   Rosenberg, Ivan ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Hybridization; Isosteric; MDS; Oligonucleotide; Phosphonate

Indexed keywords

CHEMICAL BONDS; NUCLEAR MAGNETIC RESONANCE; OPTICAL PROPERTIES; SYNTHESIS (CHEMICAL);

INTERNUCLEOTIDE BOND; OLIGONUCLEOTIDES; PHOSPHONATE;

OLIGOMERS;

DNA; INTEGRASE; MONOMER; NUCLEOSIDE ANALOG; OLIGOMER; OLIGONUCLEOTIDE; PHOSPHATE; PHOSPHODIESTERASE; PHOSPHONIC ACID DERIVATIVE; RIBONUCLEASE H; THYMIDINE; THYMINE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; ENZYME ACTIVITY; ENZYME STABILITY; HYBRIDIZATION; INTERMETHOD COMPARISON; NUCLEAR MAGNETIC RESONANCE; POLYMERIZATION; SIMULATION; SYNTHESIS; ULTRAVIOLET RADIATION;

CIRCULAR DICHROISM; COMPUTER SIMULATION; DIMERIZATION; MODELS, CHEMICAL; MODELS, MOLECULAR; OLIGONUCLEOTIDES; PHOSPHONIC ACIDS; STEREOISOMERISM;

EID: 33750575584     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20571     Document Type: Article

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