A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice

Respiratory Research

Volumn 10, Issue , 2009, Pages

  Fortin, Marylène ^a   D'Anjou, Hélène ^a   Higgins, Marie Ève ^a   Gougeon, Jasmine ^a   Aubé, Paméla ^a   Moktefi, Kamel ^a   Mouissi, Sonia ^a   Séguin, Serge ^a   Séguin, Rosanne ^a   Renzi, Paolo M ^a,b   Paquet, Luc ^c   Ferrari, Nicolay ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 2' FLUORO BETA DEXTRO ARABINONUCLEIC ACID; ANTISENSE OLIGONUCLEOTIDE; AUTACOID; CHEMOKINE; CIGARETTE SMOKE; GELATINASE B; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE IVB ANTISENSE OLIGONUCLEOTIDE; PHOSPHODIESTERASE IVD ANTISENSE OLIGONUCLEOTIDE; PHOSPHODIESTERASE VII; PHOSPHODIESTERASE VII INHIBITOR; PHOSPHODIESTERASE VIIA ANTISENSE OLIGONUCLEOTIDE; RASAYAN; ROFLUMILAST; UNCLASSIFIED DRUG; 2' DEOXY 2' FLUORO BETA D ARABINONUCLEIC ACID; 2'-DEOXY-2'-FLUORO-BETA-D-ARABINONUCLEIC ACID; ARABINONUCLEOTIDE; GAMMA INTERFERON; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTISENSE THERAPY; ARTICLE; BRONCHUS MUCOSA; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; EPITHELIUM CELL; EXPOSURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PNEUMONIA; ANIMAL; BRONCHUS; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENETICS; INFLAMMATION; LUNG; PATHOPHYSIOLOGY; SMOKE; SMOKING;

ANIMALS; ARABINONUCLEOTIDES; BRONCHI; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 7; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; HUMANS; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-1BETA; LUNG; MICE; OLIGONUCLEOTIDES, ANTISENSE; RNA, MESSENGER; SMOKE; SMOKING; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70249093993     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-10-39     Document Type: Article

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