Lyotropic liquid crystalline nanoparticles of CoQ10: Implication of lipase digestibility on oral bioavailability, in vivo antioxidant activity, and in vitro - In vivo relationships

Molecular Pharmaceutics

Volumn 11, Issue 5, 2014, Pages 1435-1449

  Swarnakar, Nitin K ^a   Thanki, Kaushik ^a   Jain, Sanyog ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Caco 2 cell uptake; coenzyme Q10 (CoQ10); enhanced bioavailability; in vitro in vivo relationship; in vivo antioxidant activity; liquid crystalline nanoparticles

Indexed keywords

ANTIOXIDANT; GLUCOSE; GLUTATHIONE; GLYCEROL OLEATE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NANOPARTICLE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL LIPASE; UBIDECARENONE; UBIQUINONE;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOAVAILABILITY; BODY WEIGHT; CACO 2 CELL LINE; DRUG DELIVERY SYSTEM; DRUG RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MOLECULAR WEIGHT; MORPHOLOGICAL TRAIT; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG EFFECTS; FEMALE; MEDICINAL CHEMISTRY; OXIDATIVE STRESS; PROCEDURES; RAT; SMALL ANGLE SCATTERING; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; CACO-2 CELLS; CHEMISTRY, PHARMACEUTICAL; FEMALE; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SCATTERING, SMALL ANGLE; UBIQUINONE;

EID: 84899871485     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400601g     Document Type: Article

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