메뉴 건너뛰기




Volumn 33, Issue 9, 2012, Pages 2723-2733

Metal-free and MRI visible theranostic lyotropic liquid crystal nitroxide-based nanoparticles

Author keywords

Contrast agent; Cubosome; Cytotoxicity; High throughput; Lyotropic liquid crystal; Maximum tolerated dose

Indexed keywords

CONTRAST AGENT; CUBOSOMES; HIGH-THROUGHPUT; LYOTROPIC LIQUID CRYSTAL; MAXIMUM TOLERATED DOSE;

EID: 84855935405     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.12.018     Document Type: Article
Times cited : (77)

References (52)
  • 1
    • 70349871400 scopus 로고    scopus 로고
    • Substantiating invivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking
    • Chertok B., David A.E., Moffat B.A., Yang V.C. Substantiating invivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking. Biomaterials 2009, 30(35):6780-6787.
    • (2009) Biomaterials , vol.30 , Issue.35 , pp. 6780-6787
    • Chertok, B.1    David, A.E.2    Moffat, B.A.3    Yang, V.C.4
  • 2
    • 36048943923 scopus 로고    scopus 로고
    • Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors
    • Chertok B., Moffat B.A., David A.E., Yu F., Bergemann C., Ross B.D., et al. Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors. Biomaterials 2008, 29(4):487-496.
    • (2008) Biomaterials , vol.29 , Issue.4 , pp. 487-496
    • Chertok, B.1    Moffat, B.A.2    David, A.E.3    Yu, F.4    Bergemann, C.5    Ross, B.D.6
  • 3
    • 9144262307 scopus 로고    scopus 로고
    • Anovel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI
    • Moffat B.A., Reddy G.R., McConville P., Hall D.E., Chenevert T.L., Kopelman R.R., et al. Anovel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI. Mol Imaging 2003, 2(4):324-332.
    • (2003) Mol Imaging , vol.2 , Issue.4 , pp. 324-332
    • Moffat, B.A.1    Reddy, G.R.2    McConville, P.3    Hall, D.E.4    Chenevert, T.L.5    Kopelman, R.R.6
  • 4
    • 67849135878 scopus 로고    scopus 로고
    • Folic acid-pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications
    • Lin J.J., Chen J.S., Huang S.J., Ko J.H., Wang Y.M., Chen T.L., et al. Folic acid-pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications. Biomaterials 2009, 30(28):5114-5124.
    • (2009) Biomaterials , vol.30 , Issue.28 , pp. 5114-5124
    • Lin, J.J.1    Chen, J.S.2    Huang, S.J.3    Ko, J.H.4    Wang, Y.M.5    Chen, T.L.6
  • 7
    • 78649746643 scopus 로고    scopus 로고
    • Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy
    • Kono K., Nakashima S., Kokuryo D., Aoki I., Shimomoto H., Aoshima S., et al. Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy. Biomaterials 2011, 32(5):1387-1395.
    • (2011) Biomaterials , vol.32 , Issue.5 , pp. 1387-1395
    • Kono, K.1    Nakashima, S.2    Kokuryo, D.3    Aoki, I.4    Shimomoto, H.5    Aoshima, S.6
  • 8
    • 65649115808 scopus 로고    scopus 로고
    • Magnetic nanoparticles for theragnostics
    • Shubayev V.I., Pisanic T.R., Jin S.H. Magnetic nanoparticles for theragnostics. Adv Drug Del Rev 2009, 61(6):467-477.
    • (2009) Adv Drug Del Rev , vol.61 , Issue.6 , pp. 467-477
    • Shubayev, V.I.1    Pisanic, T.R.2    Jin, S.H.3
  • 9
    • 0031956041 scopus 로고    scopus 로고
    • Liver-specific MR imaging contrast agents
    • Hahn P.F., Saini S. Liver-specific MR imaging contrast agents. Radiol Clin North Am. 1998, 36(2):287+.
    • (1998) Radiol Clin North Am. , vol.36 , Issue.2
    • Hahn, P.F.1    Saini, S.2
  • 10
    • 0033363494 scopus 로고    scopus 로고
    • Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications
    • Caravan P., Ellison J.J., McMurry T.J., Lauffer R.B. Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev 1999, 99(9):2293-2352.
    • (1999) Chem Rev , vol.99 , Issue.9 , pp. 2293-2352
    • Caravan, P.1    Ellison, J.J.2    McMurry, T.J.3    Lauffer, R.B.4
  • 11
    • 33744516119 scopus 로고    scopus 로고
    • Strategies for increasing the sensitivity of gadolinium based MRI contrast agents
    • Caravan P. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents. Chem Soc Rev 2006, 35(6):512-523.
    • (2006) Chem Soc Rev , vol.35 , Issue.6 , pp. 512-523
    • Caravan, P.1
  • 12
    • 34247590053 scopus 로고    scopus 로고
    • Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents
    • Laurent S., Elst L.V., Muller R.N. Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents. Contrast Media Mol Imaging 2006, 1(3):128-137.
    • (2006) Contrast Media Mol Imaging , vol.1 , Issue.3 , pp. 128-137
    • Laurent, S.1    Elst, L.V.2    Muller, R.N.3
  • 14
    • 77954382927 scopus 로고    scopus 로고
    • Customizable, multi-functional fluorocarbon nanoparticles for quantitative invivo imaging using F-19 MRI and optical imaging
    • Srinivas M., Cruz L.J., Bonetto F., Heerschap A., Figdor C.G., de Vries I.J.M. Customizable, multi-functional fluorocarbon nanoparticles for quantitative invivo imaging using F-19 MRI and optical imaging. Biomaterials 2010, 31(27):7070-7077.
    • (2010) Biomaterials , vol.31 , Issue.27 , pp. 7070-7077
    • Srinivas, M.1    Cruz, L.J.2    Bonetto, F.3    Heerschap, A.4    Figdor, C.G.5    de Vries, I.J.M.6
  • 15
    • 23444432500 scopus 로고    scopus 로고
    • Invivo imaging platform for tracking immunotherapeutic cells
    • Ahrens E.T., Flores R., Xu H.Y., Morel P.A. Invivo imaging platform for tracking immunotherapeutic cells. Nat Biotechnol 2005, 23(8):983-987.
    • (2005) Nat Biotechnol , vol.23 , Issue.8 , pp. 983-987
    • Ahrens, E.T.1    Flores, R.2    Xu, H.Y.3    Morel, P.A.4
  • 16
    • 0023615021 scopus 로고
    • Nitroxides as potential contrast enhancing agents for MRI application: influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate
    • Keana J.F.W., Pou S., Rosen G.M. Nitroxides as potential contrast enhancing agents for MRI application: influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate. Magn Reson Med 1987, 5(6):525-536.
    • (1987) Magn Reson Med , vol.5 , Issue.6 , pp. 525-536
    • Keana, J.F.W.1    Pou, S.2    Rosen, G.M.3
  • 17
    • 0022292519 scopus 로고
    • Nitroxide-doped liposomes containing entrapped oxidant: an approach to the " reduction problem" of nitroxides as MRI contrast agents
    • Keana J.F., Pou S. Nitroxide-doped liposomes containing entrapped oxidant: an approach to the " reduction problem" of nitroxides as MRI contrast agents. Physiol Chem Phys Med NMR 1985, 17(2):235-240.
    • (1985) Physiol Chem Phys Med NMR , vol.17 , Issue.2 , pp. 235-240
    • Keana, J.F.1    Pou, S.2
  • 19
    • 77951678757 scopus 로고    scopus 로고
    • Lanthanide phytanates: liquid-crystalline phase behavior, colloidal particle dispersions, and potential as medical imaging agents
    • Conn C.E., Panchagnula V., Weerawardena A., Waddington L.J., Kennedy D.F., Drummond C.J. Lanthanide phytanates: liquid-crystalline phase behavior, colloidal particle dispersions, and potential as medical imaging agents. Langmuir 2010, 26(9):6240-6249.
    • (2010) Langmuir , vol.26 , Issue.9 , pp. 6240-6249
    • Conn, C.E.1    Panchagnula, V.2    Weerawardena, A.3    Waddington, L.J.4    Kennedy, D.F.5    Drummond, C.J.6
  • 20
    • 78349295269 scopus 로고    scopus 로고
    • Chelating phytanyl-EDTA amphiphiles: self-assembly and promise as contrast agents for medical imaging
    • Moghaddam M.J., de Campo L., Waddington L.J., Drummond C.J. Chelating phytanyl-EDTA amphiphiles: self-assembly and promise as contrast agents for medical imaging. Soft Matter 2010, 6(23):5915-5929.
    • (2010) Soft Matter , vol.6 , Issue.23 , pp. 5915-5929
    • Moghaddam, M.J.1    de Campo, L.2    Waddington, L.J.3    Drummond, C.J.4
  • 22
    • 27944501644 scopus 로고    scopus 로고
    • Progress in liquid crystalline dispersions: cubosomes
    • Spicer P.T. Progress in liquid crystalline dispersions: cubosomes. Curr Opin Colloid Interface Sci 2005, 10(5-6):274-279.
    • (2005) Curr Opin Colloid Interface Sci , vol.10 , Issue.5-6 , pp. 274-279
    • Spicer, P.T.1
  • 23
    • 0000343719 scopus 로고
    • Structural relationships between lamellar, cubic and hexagonal phases in monoglyceride-water systems: possibility of cubic phases in biological systems
    • Larsson K., Fontell K., Krog N. Structural relationships between lamellar, cubic and hexagonal phases in monoglyceride-water systems: possibility of cubic phases in biological systems. Chem Phys Lipids 1980, 27:321-328.
    • (1980) Chem Phys Lipids , vol.27 , pp. 321-328
    • Larsson, K.1    Fontell, K.2    Krog, N.3
  • 24
    • 22644440788 scopus 로고
    • Acubic structure consisting of a lipid bilayer forming an infinite periodic minimum surface of the gyroid type in the glycerolmonooleat-water system
    • Hyde S.T., Andersson S., Ericsson B., Larsson K. Acubic structure consisting of a lipid bilayer forming an infinite periodic minimum surface of the gyroid type in the glycerolmonooleat-water system. ZKristallogr 1984, 168:213-219.
    • (1984) ZKristallogr , vol.168 , pp. 213-219
    • Hyde, S.T.1    Andersson, S.2    Ericsson, B.3    Larsson, K.4
  • 25
  • 26
    • 84943475814 scopus 로고
    • Structure of the cubosome-a closed lipid bilayer aggregate
    • Andersson S., Jacob M., Lidin S., Larsson K. Structure of the cubosome-a closed lipid bilayer aggregate. ZKristallogr 1995, 210:315-318.
    • (1995) ZKristallogr , vol.210 , pp. 315-318
    • Andersson, S.1    Jacob, M.2    Lidin, S.3    Larsson, K.4
  • 27
    • 58149084932 scopus 로고    scopus 로고
    • Chemistry and antihypertensive effects of tempol and other nitroxides
    • Wilcox C.S., Pearlman A. Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev 2008, 60(4):418-469.
    • (2008) Pharmacol Rev , vol.60 , Issue.4 , pp. 418-469
    • Wilcox, C.S.1    Pearlman, A.2
  • 28
    • 65349120023 scopus 로고    scopus 로고
    • Design of liposome-based pH sensitive nanospin probes: nano-sized particles with incorporated nitroxides
    • Woldman Y.Y., Semenov S.V., Bobko A.A., Kirilyuk I.A., Polienko J.F., Voinov M.A., et al. Design of liposome-based pH sensitive nanospin probes: nano-sized particles with incorporated nitroxides. Analyst 2009, 134(5):904-910.
    • (2009) Analyst , vol.134 , Issue.5 , pp. 904-910
    • Woldman, Y.Y.1    Semenov, S.V.2    Bobko, A.A.3    Kirilyuk, I.A.4    Polienko, J.F.5    Voinov, M.A.6
  • 29
    • 5844355997 scopus 로고
    • Use of nitroxides to measure redox metabolism in cells and tissues
    • Swartz H.M. Use of nitroxides to measure redox metabolism in cells and tissues. JChem Soc, Faraday Trans 1987, 83(1):191-202.
    • (1987) JChem Soc, Faraday Trans , vol.83 , Issue.1 , pp. 191-202
    • Swartz, H.M.1
  • 31
    • 0033361183 scopus 로고    scopus 로고
    • Surfactant self-assembly objects as novel drug delivery vehicles
    • Drummond C.J., Fong C. Surfactant self-assembly objects as novel drug delivery vehicles. Curr Opin Colloid Interface Sci 1999, 4(6):449-456.
    • (1999) Curr Opin Colloid Interface Sci , vol.4 , Issue.6 , pp. 449-456
    • Drummond, C.J.1    Fong, C.2
  • 32
    • 77954314331 scopus 로고    scopus 로고
    • High throughput preparation and characterisation of amphiphilic nanostructured nanoparticulate drug delivery vehicles
    • Mulet X., Kennedy D.F., Conn C.E., Hawley A., Drummond C.J. High throughput preparation and characterisation of amphiphilic nanostructured nanoparticulate drug delivery vehicles. Int J Pharm 2010, 395(1, 2):290-297.
    • (2010) Int J Pharm , vol.395 , Issue.1-2 , pp. 290-297
    • Mulet, X.1    Kennedy, D.F.2    Conn, C.E.3    Hawley, A.4    Drummond, C.J.5
  • 34
    • 70349866155 scopus 로고    scopus 로고
    • Combinatorial discovery of novel amphiphilic polymers for the phase transfer of magnetic nanoparticles
    • Muir B.W., Moffat B.A., Harbour P., Coia G., Zhen G.L., Waddington L., et al. Combinatorial discovery of novel amphiphilic polymers for the phase transfer of magnetic nanoparticles. JPhys Chem C 2009, 113(38):16615-16624.
    • (2009) JPhys Chem C , vol.113 , Issue.38 , pp. 16615-16624
    • Muir, B.W.1    Moffat, B.A.2    Harbour, P.3    Coia, G.4    Zhen, G.L.5    Waddington, L.6
  • 35
    • 78651378224 scopus 로고    scopus 로고
    • Enhanced uptake of an integral membrane protein, the dopamine D2L receptor, by cubic nanostructured lipid nanoparticles doped with Ni(II) chelated EDTA amphiphiles
    • Conn C.E., Mulet X., Moghaddam M.J., Darmanin C., Waddington L.J., Sagnella S.M., et al. Enhanced uptake of an integral membrane protein, the dopamine D2L receptor, by cubic nanostructured lipid nanoparticles doped with Ni(II) chelated EDTA amphiphiles. Soft Matter 2011, 7(2):567-578.
    • (2011) Soft Matter , vol.7 , Issue.2 , pp. 567-578
    • Conn, C.E.1    Mulet, X.2    Moghaddam, M.J.3    Darmanin, C.4    Waddington, L.J.5    Sagnella, S.M.6
  • 36
    • 0025779581 scopus 로고
    • Invivo oximetry using a nitroxide-liposome system
    • Glockner J.F., Chan H.C., Swartz H.M. Invivo oximetry using a nitroxide-liposome system. Magn Reson Med 1991, 20(1):123-133.
    • (1991) Magn Reson Med , vol.20 , Issue.1 , pp. 123-133
    • Glockner, J.F.1    Chan, H.C.2    Swartz, H.M.3
  • 37
    • 0023691320 scopus 로고
    • Delivery of nitroxide spin label to cultured cells by liposomes
    • Chan H.C., Magin R.L., Swartz H.M. Delivery of nitroxide spin label to cultured cells by liposomes. Magn Reson Med 1988, 8(2):160-170.
    • (1988) Magn Reson Med , vol.8 , Issue.2 , pp. 160-170
    • Chan, H.C.1    Magin, R.L.2    Swartz, H.M.3
  • 39
    • 79960697042 scopus 로고    scopus 로고
    • The evaluation of new and isotopically labeled isoindoline nitroxides and an azaphenalene nitroxide for EPR oximetry
    • Khan N., Blinco J.P., Bottle S.E., Hosokawa K., Swartz H.M., Micallef A.S. The evaluation of new and isotopically labeled isoindoline nitroxides and an azaphenalene nitroxide for EPR oximetry. JMagn Reson 2011, 211(2):170-177.
    • (2011) JMagn Reson , vol.211 , Issue.2 , pp. 170-177
    • Khan, N.1    Blinco, J.P.2    Bottle, S.E.3    Hosokawa, K.4    Swartz, H.M.5    Micallef, A.S.6
  • 41
    • 65249120792 scopus 로고    scopus 로고
    • Utility decay rates of T1-weighted magnetic resonance imaging contrast based on redox-sensitive paramagnetic nitroxyl contrast agents
    • Matsumoto K. Utility decay rates of T1-weighted magnetic resonance imaging contrast based on redox-sensitive paramagnetic nitroxyl contrast agents. Biol Pharm Bull 2009, 32(4):711-716.
    • (2009) Biol Pharm Bull , vol.32 , Issue.4 , pp. 711-716
    • Matsumoto, K.1
  • 42
    • 39049141266 scopus 로고    scopus 로고
    • Poly(amidoamine)s carrying TEMPO residues for NMR imaging applications
    • Gussoni M., Greco F., Ferruti P., Ranucci E., Ponti A., Zetta L. Poly(amidoamine)s carrying TEMPO residues for NMR imaging applications. New J Chem 2008, 32(2):323-332.
    • (2008) New J Chem , vol.32 , Issue.2 , pp. 323-332
    • Gussoni, M.1    Greco, F.2    Ferruti, P.3    Ranucci, E.4    Ponti, A.5    Zetta, L.6
  • 43
    • 0030148764 scopus 로고    scopus 로고
    • The temperature-composition phase diagram and mesophase structure characterization of the monoolein/water system
    • Briggs J., Chung H., Caffrey M. The temperature-composition phase diagram and mesophase structure characterization of the monoolein/water system. Journal De Physique Ii 1996, 6(5):723-751.
    • (1996) Journal De Physique Ii , vol.6 , Issue.5 , pp. 723-751
    • Briggs, J.1    Chung, H.2    Caffrey, M.3
  • 44
    • 77955875402 scopus 로고    scopus 로고
    • Direct visualisation of lipid bilayer cubic phases using atomic force microscopy
    • Rittman M., Frischherz M., Burgmann F., Hartley P.G., Squires A. Direct visualisation of lipid bilayer cubic phases using atomic force microscopy. Soft Matter 2010, 6(17):4058-4061.
    • (2010) Soft Matter , vol.6 , Issue.17 , pp. 4058-4061
    • Rittman, M.1    Frischherz, M.2    Burgmann, F.3    Hartley, P.G.4    Squires, A.5
  • 45
    • 78149405873 scopus 로고    scopus 로고
    • Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast
    • Ananta J.S., Godin B., Sethi R., Moriggi L., Liu X.W., Serda R.E., et al. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nature Nanotech 2010, 5(11):815-821.
    • (2010) Nature Nanotech , vol.5 , Issue.11 , pp. 815-821
    • Ananta, J.S.1    Godin, B.2    Sethi, R.3    Moriggi, L.4    Liu, X.W.5    Serda, R.E.6
  • 46
    • 78149466752 scopus 로고    scopus 로고
    • The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions
    • Shen H.H., Crowston J.G., Huber F., Saubern S., McLean K.M., Hartley P.G. The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions. Biomaterials 2010, 31(36):9473-9481.
    • (2010) Biomaterials , vol.31 , Issue.36 , pp. 9473-9481
    • Shen, H.H.1    Crowston, J.G.2    Huber, F.3    Saubern, S.4    McLean, K.M.5    Hartley, P.G.6
  • 47
    • 77953942346 scopus 로고    scopus 로고
    • Nanoparticles from lipid-based liquid crystals: emulsifier influence on morphology and cytotoxicity
    • Murgia S., Falchi A.M., Mano M., Lampis S., Angius R., Carnerup A.M., et al. Nanoparticles from lipid-based liquid crystals: emulsifier influence on morphology and cytotoxicity. JPhys Chem B 2010, 114(10):3518-3525.
    • (2010) JPhys Chem B , vol.114 , Issue.10 , pp. 3518-3525
    • Murgia, S.1    Falchi, A.M.2    Mano, M.3    Lampis, S.4    Angius, R.5    Carnerup, A.M.6
  • 48
    • 79959216906 scopus 로고    scopus 로고
    • Nanostructured self-assembly materials from neat and aqueous solutions of C18 lipid pro-drug analogues of Capecitabine-a chemotherapy agent: focus on nanoparticulate cubosomes of the oleyl analogue
    • Gong X.J., Moghaddam M.J., Sagnella S.M., Conn C.E., Mulet X., Danon S.J., et al. Nanostructured self-assembly materials from neat and aqueous solutions of C18 lipid pro-drug analogues of Capecitabine-a chemotherapy agent: focus on nanoparticulate cubosomes of the oleyl analogue. Soft Matter 2011, 7(12):5764-5776.
    • (2011) Soft Matter , vol.7 , Issue.12 , pp. 5764-5776
    • Gong, X.J.1    Moghaddam, M.J.2    Sagnella, S.M.3    Conn, C.E.4    Mulet, X.5    Danon, S.J.6
  • 49
    • 79952596766 scopus 로고    scopus 로고
    • Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination
    • Fong C., Weerawardena A., Sagnella S.M., Mulet X., Krodkiewska I., Chong J., et al. Monodisperse nonionic isoprenoid-type hexahydrofarnesyl ethylene oxide surfactants: high throughput lyotropic liquid crystalline phase determination. Langmuir 2011, 27(6):2317-2326.
    • (2011) Langmuir , vol.27 , Issue.6 , pp. 2317-2326
    • Fong, C.1    Weerawardena, A.2    Sagnella, S.M.3    Mulet, X.4    Krodkiewska, I.5    Chong, J.6
  • 50
    • 80051623994 scopus 로고    scopus 로고
    • Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds
    • Dong Y.-D., Larson I., Bames T.J., Prestidge C.A., Boyd B.J. Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds. ACS Appl Mater Interfaces 2011, 3(5):1771-1780.
    • (2011) ACS Appl Mater Interfaces , vol.3 , Issue.5 , pp. 1771-1780
    • Dong, Y.-D.1    Larson, I.2    Bames, T.J.3    Prestidge, C.A.4    Boyd, B.J.5
  • 51
    • 80053275944 scopus 로고    scopus 로고
    • Differences in colloidal structure of pegylated nanomaterials dictate the likelihood of accelerated blood clearance
    • Kaminskas L.M., McLeod V.M.H., Porter C.J., Boyd B.J. Differences in colloidal structure of pegylated nanomaterials dictate the likelihood of accelerated blood clearance. JPharm Sci 2011, 100(11):5069-5077.
    • (2011) JPharm Sci , vol.100 , Issue.11 , pp. 5069-5077
    • Kaminskas, L.M.1    McLeod, V.M.H.2    Porter, C.J.3    Boyd, B.J.4
  • 52
    • 0024551243 scopus 로고
    • Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues
    • Allen T.M., Hansen C., Rutledge J. Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues. Biochim Biophys Acta 1989, 981(1):27-35.
    • (1989) Biochim Biophys Acta , vol.981 , Issue.1 , pp. 27-35
    • Allen, T.M.1    Hansen, C.2    Rutledge, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.