Gelatin coated hybrid lipid nanoparticles for oral delivery of Amphotericin B

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2542-2553

  Jain, Sanyog ^a   Valvi, Pankaj U ^a   Swarnakar, Nitin K ^a   Thanki, Kaushik ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

amphotericin B; gelatin; lecithin; nephrotoxicity; oral delivery; polymer lipid hybrid nanoparticles (PLNs)

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; CREATININE; GELATIN; LIPID HYBRID NANOPARTICLE; NANOCARRIER; NITROGEN; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; CELL STRAIN CACO 2; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; DRUG UPTAKE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FREEZE DRYING; HEMOLYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE MUCOSA PERMEABILITY; ISOELECTRIC POINT; MALE; MATERIAL COATING; MAXIMUM PLASMA CONCENTRATION; NEPHROTOXICITY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; UREA NITROGEN BLOOD LEVEL; ZETA POTENTIAL;

ADMINISTRATION, ORAL; AMPHOTERICIN B; ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; FREEZE DRYING; GELATIN; HUMANS; INTESTINAL ABSORPTION; KIDNEY TUBULES; KINETICS; LECITHINS; LIPIDS; MALE; MICE; NANOPARTICLES; PARTICLE SIZE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84865966794     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300320d     Document Type: Article

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