Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration

Journal of Controlled Release

Volumn 153, Issue 2, 2011, Pages 180-186

  Nguyen, Tri Hung ^a   Hanley, Tracey ^b   Porter, Christopher J H ^a   Boyd, Ben J ^a  

^a MONASH UNIVERSITY   (Australia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

Author keywords

Glyceryl monooleate; Liquid crystal; Nanostructured particles; Oral drug delivery; Phytantriol; Sustained release

Indexed keywords

GLYCERYL MONOOLEATE; NANOSTRUCTURED PARTICLES; ORAL DRUG DELIVERY; PHYTANTRIOL; SUSTAINED-RELEASE;

BIOCHEMISTRY; DRUG DELIVERY; DRUG PRODUCTS; EMULSIFICATION; LIQUID CRYSTALS; OLEIC ACID; PHOTODEGRADATION; RESERVOIRS (WATER); SUSPENSIONS (FLUIDS); WATER ABSORPTION;

NANOSTRUCTURES;

CINNARIZINE; GLYCEROL OLEATE; NANOCRYSTAL; NANOMATERIAL; NANOPARTICLE; OLEIC ACID; PHYTANTRIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM COMPARISON; EMULSION; LIQUID CRYSTAL; MALE; NANOPHARMACEUTICS; NONHUMAN; PRIORITY JOURNAL; RAT; SUSPENSION; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION;

ADMINISTRATION, ORAL; ANIMALS; CINNARIZINE; DELAYED-ACTION PREPARATIONS; FATTY ALCOHOLS; GLYCERIDES; HISTAMINE H1 ANTAGONISTS; LIQUID CRYSTALS; MALE; NANOSTRUCTURES; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; WATER;

EID: 79960078025     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.033     Document Type: Article

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