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Volumn 8, Issue 2, 2011, Pages 466-478

Doxorubicin-loaded (PEG)3-PLA nanopolymersomes: Effect of solvents and process parameters on formulation development and in vitro study

Author keywords

(PEG)3 PLA; amphiphilic copolymer; doxorubicin; nanopolymersomes; self assembly

Indexed keywords

DOXORUBICIN; MACROGOL; POLYLACTIC ACID;

EID: 79953828616     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp1003256     Document Type: Article
Times cited : (54)

References (53)
  • 4
    • 2542458246 scopus 로고    scopus 로고
    • Membrane solubilization by detergent: Resistance confered by thickness
    • Pata, V.; Ahmed, F.; Discher, D. E.; Dan, N. Membrane solubilization by detergent: resistance confered by thickness. Langmuir 2004, 20, 3888-3893.
    • (2004) Langmuir , vol.20 , pp. 3888-3893
    • Pata, V.1    Ahmed, F.2    Discher, D.E.3    Dan, N.4
  • 5
  • 6
    • 0037047627 scopus 로고    scopus 로고
    • Polymer vesicles
    • DOI 10.1126/science.1074972
    • Discher, D. E.; Eisenberg, A. Polymer vesicles. Science 2002, 297, 967-73. (Pubitemid 34856022)
    • (2002) Science , vol.297 , Issue.5583 , pp. 967-973
    • Discher, D.E.1    Eisenberg, A.2
  • 7
    • 1842526004 scopus 로고    scopus 로고
    • Self-porating polymersomes of PEG-PLA and PEG-PCL: Hydrolysis-triggered controlled release vesicles
    • DOI 10.1016/j.jconrel.2003.12.021, PII S0168365903006084
    • Ahmed, F.; Discher, D. E. Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles. J. Controlled Release 2004, 96, 37-53. (Pubitemid 38438488)
    • (2004) Journal of Controlled Release , vol.96 , Issue.1 , pp. 37-53
    • Ahmed, F.1    Discher, D.E.2
  • 8
    • 33845296078 scopus 로고    scopus 로고
    • Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug
    • DOI 10.1016/j.jconrel.2006.07.012, PII S016836590600335X
    • Ahmed, F.; Pakunlu, R. I.; Brannan, A.; Bates, F. S.; Minko, T.; Discher, D. E. Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug. J. Controlled Release 2006, 116, 150-8. (Pubitemid 44868999)
    • (2006) Journal of Controlled Release , vol.116 , Issue.2 SPEC. ISS , pp. 150-158
    • Ahmed, F.1    Pakunlu, R.I.2    Brannan, A.3    Bates, F.4    Minko, T.5    Discher, D.E.6
  • 9
    • 25844472606 scopus 로고    scopus 로고
    • Novel biomimetic polymersomes as polymer therapeutics for drug delivery
    • DOI 10.1016/j.jconrel.2005.06.013, PII S0168365905002816
    • Xu, J. P.; Ji, J.; Chen, W.; Shen, J. Novel biomimetic polymersomes as polymer therapeutics for drug delivery. J. Controlled Release 2005, 107, 502-512. (Pubitemid 41393357)
    • (2005) Journal of Controlled Release , vol.107 , Issue.3 , pp. 502-512
    • Xu, J.-P.1    Ji, J.2    Chen, W.-D.3    Shen, J.-C.4
  • 10
    • 68649100989 scopus 로고    scopus 로고
    • A novel method for the encapsulation of biomolecules into polymersomes via direct hydration
    • O'Nell, C. P.; Suzuki, T.; Demurtas, D.; Finka, A.; Hubbell, J. A. A novel method for the encapsulation of biomolecules into polymersomes via direct hydration. Langmuir 2009, 25, 9025-9029.
    • (2009) Langmuir , vol.25 , pp. 9025-9029
    • O'Nell, C.P.1    Suzuki, T.2    Demurtas, D.3    Finka, A.4    Hubbell, J.A.5
  • 12
    • 77955279339 scopus 로고    scopus 로고
    • Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs
    • Licciardi, M.; Paolino, D.; Giammona, G.; Cavallaro, G.; Fresta, M. Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs. Biomaterials 2010, 31, 7340-7354.
    • (2010) Biomaterials , vol.31 , pp. 7340-7354
    • Licciardi, M.1    Paolino, D.2    Giammona, G.3    Cavallaro, G.4    Fresta, M.5
  • 15
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • Moghimi, S. M.; Hunter, A. C.; Murray, J. C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 2001, 53, 283-318.
    • (2001) Pharmacol. Rev. , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 16
    • 33847256524 scopus 로고    scopus 로고
    • A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: Micelles, nanospheres, nanocapsules and polymersomes
    • Letchford, K.; Burt, H. A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes. Eur. J. Pharm. Biopharm. 2007, 65, 259-269.
    • (2007) Eur. J. Pharm. Biopharm. , vol.65 , pp. 259-269
    • Letchford, K.1    Burt, H.2
  • 17
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis, F.; Pridgen, E.; Molnar, L. K.; Farokzhad, O. C. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharmaceutics 2008, 5, 505-515.
    • (2008) Mol. Pharmaceutics , vol.5 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokzhad, O.C.4
  • 18
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li, S.-D.; Huang, L. Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharmaceutics 2008, 5, 496-504.
    • (2008) Mol. Pharmaceutics , vol.5 , pp. 496-504
    • Li, S.-D.1    Huang, L.2
  • 19
    • 70349542520 scopus 로고    scopus 로고
    • Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer
    • Li, S.-D.; Huang, L. Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer. Biochim. Biophys. Acta 2009, 1788, 2259-2266.
    • (2009) Biochim. Biophys. Acta , vol.1788 , pp. 2259-2266
    • Li, S.-D.1    Huang, L.2
  • 21
    • 0343191443 scopus 로고    scopus 로고
    • 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): Influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption
    • DOI 10.1016/S0927-7765(99)00156-3, PII S0927776599001563
    • Gref, R.; Luck, M.; Quellec, P.; Marchand, M.; Dellacherie, E.; Harnisch, S. Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf., B 2000, 18, 301-313. (Pubitemid 30479870)
    • (2000) Colloids and Surfaces B: Biointerfaces , vol.18 , Issue.3-4 , pp. 301-313
    • Gref, R.1    Luck, M.2    Quellec, P.3    Marchand, M.4    Dellacherie, E.5    Harnisch, S.6    Blunk, T.7    Muller, R.H.8
  • 24
    • 0032952283 scopus 로고    scopus 로고
    • PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug
    • DOI 10.1016/S0168-3659(98)00116-3, PII S0168365998001163
    • Govender, T.; Stolnik, S.; Garnett, M. C.; Illum, L.; Davis, S. S. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J. Controlled Release 1999, 57, 171-185. (Pubitemid 29062869)
    • (1999) Journal of Controlled Release , vol.57 , Issue.2 , pp. 171-185
    • Govender, T.1    Stolnik, S.2    Garnett, M.C.3    Illum, L.4    Davis, S.S.5
  • 25
    • 34249815817 scopus 로고    scopus 로고
    • Doxorubicin-loaded PLGA nanoparticles by nanoprecipitation: Preparation, characterization and in vitro evaluation
    • DOI 10.2217/17435889.2.2.219
    • Betancourt, T.; Brown, B.; Brannon-Peppas, L. Doxorubicin-loaded PLGA nanoparticles by nanoprecipitation: preparation, characterization and in vitro evaluation. Nanomedicine 2007, 2, 219-232. (Pubitemid 46845768)
    • (2007) Nanomedicine , vol.2 , Issue.2 , pp. 219-232
    • Betancourt, T.1    Brown, B.2    Brannon-Peppas, L.3
  • 26
    • 12344337457 scopus 로고    scopus 로고
    • PLGA nanoparticles containing praziquantel: Effect of formulation variables on size distribution
    • Mainardes, R. M.; Evangelista, R. C. PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution. Int. J. Pharm. 2005, 290, 137-144.
    • (2005) Int. J. Pharm. , vol.290 , pp. 137-144
    • Mainardes, R.M.1    Evangelista, R.C.2
  • 27
    • 0033980297 scopus 로고    scopus 로고
    • Doxorubicin-loaded poly(ethylene glycol)-poly([beta]-benzyl--aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance
    • Kataoka, K.; Matsumoto, T.; Yokoyama, M.; Okano, T.; Sakurai, Y.; Fukushima, S.; Okamoto, K.; Kwon, G. S. Doxorubicin-loaded poly(ethylene glycol)-poly([beta]-benzyl--aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance. J. Controlled Release 2000, 64, 143-153.
    • (2000) J. Controlled Release , vol.64 , pp. 143-153
    • Kataoka, K.1    Matsumoto, T.2    Yokoyama, M.3    Okano, T.4    Sakurai, Y.5    Fukushima, S.6    Okamoto, K.7    Kwon, G.S.8
  • 28
    • 4143074645 scopus 로고    scopus 로고
    • Micellar carriers based on block copolymers of poly([var epsilon]-caprolactone) and poly(ethylene glycol) for doxorubicin delivery
    • Shuai, X.; Ai, H.; Nasongkla, N.; Kim, S.; Gao, J. Micellar carriers based on block copolymers of poly([var epsilon]-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J. Controlled Release 2004, 98, 415-426.
    • (2004) J. Controlled Release , vol.98 , pp. 415-426
    • Shuai, X.1    Ai, H.2    Nasongkla, N.3    Kim, S.4    Gao, J.5
  • 29
    • 13444254143 scopus 로고    scopus 로고
    • In vitro study of anticancer drug doxorubicin in PLGA-based microparticles
    • Lina, R.; Nga, L. S.; Wang, C. In vitro study of anticancer drug doxorubicin in PLGA-based microparticles. Biomaterials 2005, 26, 4476-4481.
    • (2005) Biomaterials , vol.26 , pp. 4476-4481
    • Lina, R.1    Nga, L.S.2    Wang, C.3
  • 31
    • 33845930266 scopus 로고    scopus 로고
    • PEG-PLA block-copolymer as potential drug carrier: Preparation and characterization
    • Ben-Shabat, S.; Kumar, N.; Domb, A. PEG-PLA block-copolymer as potential drug carrier: preparation and characterization. Macromol. Biosci. 2006, 6, 1019-1025.
    • (2006) Macromol. Biosci. , vol.6 , pp. 1019-1025
    • Ben-Shabat, S.1    Kumar, N.2    Domb, A.3
  • 32
    • 77950831378 scopus 로고    scopus 로고
    • 3-PLA copolymer as polymersomes: Preparation, characterization and their evaluation as drug carrier
    • 3-PLA copolymer as polymersomes: preparation, characterization and their evaluation as drug carrier. Biomacromolecules 2010, 11, 1027-1035.
    • (2010) Biomacromolecules , vol.11 , pp. 1027-1035
    • Jain, J.P.1    Kumar, N.2
  • 33
    • 77953914712 scopus 로고    scopus 로고
    • Development of amphotericin B-loaded polymersomes based on (PEG)3-PLA co-polymers: Factors affecting size and in vitro evaluation
    • Jain, J. P.; Kumar, N. Development of amphotericin B-loaded polymersomes based on (PEG)3-PLA co-polymers: Factors affecting size and in vitro evaluation. Eur. J. Pharm. Sci. 2010, 40, 456-465.
    • (2010) Eur. J. Pharm. Sci. , vol.40 , pp. 456-465
    • Jain, J.P.1    Kumar, N.2
  • 34
    • 78650696904 scopus 로고    scopus 로고
    • Effect of PEG chain length and hydrophilic weight fraction on polymersomes prepared from branched (PEG)3-PLA co-polymers
    • Ayen, W. Y.; Chintankumar, B.; Jain, J. P.; Kumar, N. Effect of PEG chain length and hydrophilic weight fraction on polymersomes prepared from branched (PEG)3-PLA co-polymers. Polym. Adv. Technol. 2011, 22, 158-165.
    • (2011) Polym. Adv. Technol. , vol.22 , pp. 158-165
    • Ayen, W.Y.1    Chintankumar, B.2    Jain, J.P.3    Kumar, N.4
  • 36
    • 77149170850 scopus 로고    scopus 로고
    • Biocompatible and biodegradable poly(trimethylene carbonate)-b-poly(L- glutamic acid) polymersomes: Size control and stability
    • Sanson, C.; Schatz, C.; Le Meins, J. F.; Brûlet, A.; Soum, A.; Lecommandoux, S. Biocompatible and biodegradable poly(trimethylene carbonate)-b-poly(L-glutamic acid) polymersomes: Size control and stability. Langmuir 2010, 26, 2751-2760.
    • (2010) Langmuir , vol.26 , pp. 2751-2760
    • Sanson, C.1    Schatz, C.2    Le Meins, J.F.3    Brûlet, A.4    Soum, A.5    Lecommandoux, S.6
  • 37
    • 34250631317 scopus 로고    scopus 로고
    • Formation and characterization of polymersomes made by a solvent injection method
    • Yildiz, M. E.; Prud'homme, R. K.; Robb, I.; Adamson, D. H. Formation and characterization of polymersomes made by a solvent injection method. Polym. Adv. Technol. 2007, 18, 427-432.
    • (2007) Polym. Adv. Technol. , vol.18 , pp. 427-432
    • Yildiz, M.E.1    Prud'homme, R.K.2    Robb, I.3    Adamson, D.H.4
  • 39
    • 33744816176 scopus 로고    scopus 로고
    • Dewetting instability during the formation of polymersomes from block-copolymer-stabilized double emulsions
    • DOI 10.1021/la060094b
    • Hayward, R. C.; Utada, A. S.; Dan, N.; Weitz, D. A. Dewetting instability during the formation of polymersomes from block-copolymer-stabilized double emulsions. Langmuir 2006, 22, 4457-4461. (Pubitemid 43829116)
    • (2006) Langmuir , vol.22 , Issue.10 , pp. 4457-4461
    • Hayward, R.C.1    Utada, A.S.2    Dan, N.3    Weitz, D.A.4
  • 42
    • 34547766051 scopus 로고    scopus 로고
    • PLA nano-and microparticles for drug delivery: An overview of the methods of preparation
    • Lassalle, V.; Ferreira, M. L. PLA nano-and microparticles for drug delivery: an overview of the methods of preparation. Macromol. Biosci. 2007, 7, 767-783.
    • (2007) Macromol. Biosci. , vol.7 , pp. 767-783
    • Lassalle, V.1    Ferreira, M.L.2
  • 43
    • 78649687712 scopus 로고    scopus 로고
    • Rapid preparation of polymersomes by a water addition/solvent evaporation method
    • Marsden, H. R.; Gabrielli, L.; Kros, A. Rapid preparation of polymersomes by a water addition/solvent evaporation method. Polym. Chem. 2010, 1, 1512-1518.
    • (2010) Polym. Chem. , vol.1 , pp. 1512-1518
    • Marsden, H.R.1    Gabrielli, L.2    Kros, A.3
  • 44
    • 77955013371 scopus 로고    scopus 로고
    • Polymersomes, smaller than you think: Ferrocene as a TEM probe to determine core structure
    • Johnston, A. H.; Dalton, P. D.; Newman, T. A. Polymersomes, smaller than you think: ferrocene as a TEM probe to determine core structure. J. Nanopart Res 2010, 12, 1997-2001.
    • (2010) J. Nanopart Res , vol.12 , pp. 1997-2001
    • Johnston, A.H.1    Dalton, P.D.2    Newman, T.A.3
  • 46
    • 2542485276 scopus 로고    scopus 로고
    • Polystyrene-b-poly-(acrylic acid) vesicle size control using solution properties and hydrophilic block length
    • Choucair, A.; Lavigueur, C.; Eisenberg, A. Polystyrene-b-poly-(acrylic acid) vesicle size control using solution properties and hydrophilic block length. Langmuir 2004, 20, 3894-3900.
    • (2004) Langmuir , vol.20 , pp. 3894-3900
    • Choucair, A.1    Lavigueur, C.2    Eisenberg, A.3
  • 47
    • 0038237042 scopus 로고    scopus 로고
    • Controll of amphiphilic block copolymer morphologies using solution conditions
    • Choucair, A.; Eisenberg, A. Controll of amphiphilic block copolymer morphologies using solution conditions. Eur. Phys. J. E 2003, 10, 37-44.
    • (2003) Eur. Phys. J. E , vol.10 , pp. 37-44
    • Choucair, A.1    Eisenberg, A.2
  • 48
    • 29844442167 scopus 로고    scopus 로고
    • pH sensitive vesicles based on a biocompatible zwitterionic diblock copolymer
    • Du, J. Z.; Tang, Y. P.; Lewis, A. L.; Arms, S. P. pH sensitive vesicles based on a biocompatible zwitterionic diblock copolymer. J. Am. Chem. Soc. 2005, 127, 17982-17983.
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 17982-17983
    • Du, J.Z.1    Tang, Y.P.2    Lewis, A.L.3    Arms, S.P.4
  • 49
    • 33644951214 scopus 로고    scopus 로고
    • Bioresorbable vesicles formed through spontaneous self-assembly of amphiphilic poly(ethylene oxide)-block-polycaprolactone
    • Ghoroghchian, P. P.; Li, G.; Levine, D. H.; Davis, K. P.; Bates, F. S.; Hammer, D. A.; Therien, M. J. Bioresorbable vesicles formed through spontaneous self-assembly of amphiphilic poly(ethylene oxide)-block-polycaprolactone. Macromolecules 2006, 39, 1673-1675.
    • (2006) Macromolecules , vol.39 , pp. 1673-1675
    • Ghoroghchian, P.P.1    Li, G.2    Levine, D.H.3    Davis, K.P.4    Bates, F.S.5    Hammer, D.A.6    Therien, M.J.7
  • 50
    • 10044286158 scopus 로고    scopus 로고
    • Biodegradable polymersomes as a basis for artificial cells: Encapsulation, release and targeting
    • DOI 10.1016/j.jconrel.2004.09.026, PII S0168365904004286
    • Meng, F. H.; Engbers, G. H. M.; Feijen, J. Biodegradable polymersomes as a basis for artificial cells: encapsulation, release and targeting. J. Controlled Release 2005, 101, 187-198. (Pubitemid 39600982)
    • (2005) Journal of Controlled Release , vol.101 , Issue.1-3 SPEC. ISS , pp. 187-198
    • Meng, F.1    Engbers, G.H.M.2    Feijen, J.3
  • 51
    • 76749128372 scopus 로고    scopus 로고
    • pH sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles
    • Chen, W.; Meng, F.; Cheng, R.; Zhong, Z. pH sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles. J. Controlled Release 2009, 142, 40-46.
    • (2009) J. Controlled Release , vol.142 , pp. 40-46
    • Chen, W.1    Meng, F.2    Cheng, R.3    Zhong, Z.4
  • 52
    • 33745770615 scopus 로고    scopus 로고
    • Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: PH-triggered release through copolymer degradation
    • DOI 10.1021/mp050103u
    • Ahmed, F.; Pakunlu, R. I.; Srinivas, G.; Brannan, A.; Bates, F.; Klein, M. L.; Minko, T.; Discher, D. E. Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation. Mol. Pharmaceutics 2006, 3, 340-50. (Pubitemid 44021440)
    • (2006) Molecular Pharmaceutics , vol.3 , Issue.3 , pp. 340-350
    • Ahmed, F.1    Pakunlu, R.I.2    Srinivas, G.3    Brannan, A.4    Bates, F.5    Klein, M.L.6    Minko, T.7    Discher, D.E.8
  • 53
    • 0000972145 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor activities of nanoparticles based on doxorubicin-PLGA conjugates
    • Yoo, H. S.; Lee, K. H.; Oh, J. E.; Park, T. G. In vitro and in vivo antitumor activities of nanoparticles based on doxorubicin-PLGA conjugates. J. Controlled Release 2001, 68, 419-431.
    • (2001) J. Controlled Release , vol.68 , pp. 419-431
    • Yoo, H.S.1    Lee, K.H.2    Oh, J.E.3    Park, T.G.4


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