An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation

Molecular and Cellular Proteomics

Volumn 13, Issue 5, 2014, Pages 1184-1197

  Turowec, Jacob P ^a   Zukowski, Stephanie A ^a   Knight, James D R ^b   Smalley, David M ^c   Graves, Lee M ^c   Johnson, Gary L ^c   Li, Shawn S C ^a   Lajoie, Gilles A ^a   Litchfield, David W ^a  

^a WESTERN UNIVERSITY   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; GOLGIN 160; MST3 PROTEIN; PHOSPHOSERINE; PROTEIN; SYNTHETIC PEPTIDE; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG; CASPASE; MEMBRANE PROTEIN; PEPTIDE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; STK24 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CELL SURVIVAL; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEOMICS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; CHEMICAL STRUCTURE; CHEMISTRY; HELA CELL LINE; METABOLISM; PHOSPHORYLATION; PROCEDURES; PROTEIN DEGRADATION; PROTEIN PROCESSING;

CASPASES; HELA CELLS; HUMANS; ISOTOPE LABELING; MEMBRANE PROTEINS; MODELS, MOLECULAR; PEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; PROTEOMICS;

EID: 84899750481     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M113.037374     Document Type: Article

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