Structural basis for executioner caspase recognition of P5 position in substrates

Apoptosis

Volumn 13, Issue 11, 2008, Pages 1291-1302

  Fu, Guoxing ^a   Chumanevich, Alexander A ^a   Agniswamy, Johnson ^a   Fang, Bin ^a   Harrison, Robert W ^a   Weber, Irene T ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Cysteine protease; Enzyme catalysis; Induced fit; Protein recognition

Indexed keywords

ASPARTYLGLUTAMYLVALYLASPARTIC ACID; CASPASE; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; GLUTAMINYLASPARTYLGLUTAMYLVALYLASPARTIC ACID; LEUCYLASPARTYLGLUTAMYLSERYLASPARTIC ACID; LEUCYLASPARTYLGLUTAMYLVALYLASPARTIC ACID; PENTAPEPTIDE; PEPTIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME BINDING; HYDROLYSIS; KINETICS; MODEL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; HUMANS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 53849142861     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0259-9     Document Type: Article

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