-
1
-
-
77955129487
-
Liver x receptor signaling pathways and atherosclerosis
-
Calkin AC, Tontonoz P. Liver x receptor signaling pathways and atherosclerosis. Arterioscler Thromb Vasc Biol. 2010;30(8):1513-1518.
-
(2010)
Arterioscler Thromb Vasc Biol.
, vol.30
, Issue.8
, pp. 1513-1518
-
-
Calkin, A.C.1
Tontonoz, P.2
-
2
-
-
34848827936
-
Targeting thyroid hormone receptor- beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index
-
Erion MD, et al. Targeting thyroid hormone receptor- beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. Proc Natl Acad Sci U S A. 2007;104(39):15490-15495.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, Issue.39
, pp. 15490-15495
-
-
Erion, M.D.1
-
3
-
-
38649135692
-
The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans
-
Berkenstam A, et al. The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans. Proc Natl Acad Sci U S A. 2008;105(2):663-667.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.2
, pp. 663-667
-
-
Berkenstam, A.1
-
4
-
-
77949349469
-
Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia
-
Ladenson PW, et al. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. N Engl J Med. 2010;362(10):906-916.
-
(2010)
N Engl J Med.
, vol.362
, Issue.10
, pp. 906-916
-
-
Ladenson, P.W.1
-
5
-
-
22644432001
-
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice
-
Johansson L, et al. Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice. Proc Natl Acad Sci U S A. 2005; 102(29):10297-10302.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, Issue.29
, pp. 10297-10302
-
-
Johansson, L.1
-
6
-
-
77649284831
-
The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice
-
Tancevski I, et al. The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice. PLoS One. 2010;5(1):e8722.
-
(2010)
PLoS One.
, vol.5
, Issue.1
-
-
Tancevski, I.1
-
7
-
-
0033650847
-
Thyroid hormone receptor betadeficient mice show complete loss of the normal cholesterol 7-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol
-
Gullberg H, Rudling M, Forrest D, Angelin B, Vennstrom B. Thyroid hormone receptor betadeficient mice show complete loss of the normal cholesterol 7-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. Mol Endocrinol. 2000;14(11):1739-1749.
-
(2000)
Mol Endocrinol.
, vol.14
, Issue.11
, pp. 1739-1749
-
-
Gullberg, H.1
Rudling, M.2
Forrest, D.3
Angelin, B.4
Vennstrom, B.5
-
8
-
-
0842269844
-
Regulation of the human cholesterol 7-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice
-
Drover VA, Agellon LB. Regulation of the human cholesterol 7-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice. Endocrinology. 2004;145(2):574-581.
-
(2004)
Endocrinology.
, vol.145
, Issue.2
, pp. 574-581
-
-
Drover, V.A.1
Agellon, L.B.2
-
9
-
-
84870167700
-
Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor
-
Lin JZ, et al. Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor. Endocrinology. 2012;153(12):6136-6144.
-
(2012)
Endocrinology.
, vol.153
, Issue.12
, pp. 6136-6144
-
-
Lin, J.Z.1
-
10
-
-
0019427798
-
Cholesterol metabolism in hypothyroidism and hyperthyroidism in man
-
Abrams JJ, Grundy SM. Cholesterol metabolism in hypothyroidism and hyperthyroidism in man. J Lipid Res. 1981;22(2):323-338.
-
(1981)
J Lipid Res.
, vol.22
, Issue.2
, pp. 323-338
-
-
Abrams, J.J.1
Grundy, S.M.2
-
11
-
-
41549144021
-
Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone
-
Galman C, Bonde Y, Matasconi M, Angelin B, Rudling M. Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone. Gastroenterology. 2008;134(4):1127-1136.
-
(2008)
Gastroenterology.
, vol.134
, Issue.4
, pp. 1127-1136
-
-
Galman, C.1
Bonde, Y.2
Matasconi, M.3
Angelin, B.4
Rudling, M.5
-
12
-
-
84868191164
-
Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex
-
Bonde Y, Plosch T, Kuipers F, Angelin B, Rudling M. Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex. Hepatology. 2012;56(5):1828-1837.
-
(2012)
Hepatology.
, vol.56
, Issue.5
, pp. 1828-1837
-
-
Bonde, Y.1
Plosch, T.2
Kuipers, F.3
Angelin, B.4
Rudling, M.5
-
13
-
-
0036020496
-
Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice
-
Gullberg H, Rudling M, Salto C, Forrest D, Angelin B, Vennstrom B. Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice. Mol Endocrinol. 2002;16(8):1767-1777.
-
(2002)
Mol Endocrinol.
, vol.16
, Issue.8
, pp. 1767-1777
-
-
Gullberg, H.1
Rudling, M.2
Salto, C.3
Forrest, D.4
Angelin, B.5
Vennstrom, B.6
-
14
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXR?
-
Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ. An oxysterol signalling pathway mediated by the nuclear receptor LXR?. Nature. 1996;383(6602):728-731.
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
15
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR?
-
Peet DJ, et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR?. Cell. 1998;93(5):693-704.
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 693-704
-
-
Peet, D.J.1
-
16
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXR-deficient mice
-
Alberti S, et al. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXR-deficient mice. J Clin Invest. 2001;107(5):565-573.
-
(2001)
J Clin Invest.
, vol.107
, Issue.5
, pp. 565-573
-
-
Alberti, S.1
-
17
-
-
84860548049
-
Liver LXRalpha expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice
-
Zhang Y, et al. Liver LXRalpha expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice. J Clin Invest. 2012;122(5):1688-1699.
-
(2012)
J Clin Invest.
, vol.122
, Issue.5
, pp. 1688-1699
-
-
Zhang, Y.1
-
18
-
-
0035834868
-
Regulation of cholesterol 7-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXR)
-
Chiang JY, Kimmel R, Stroup D. Regulation of cholesterol 7-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXR). Gene. 2001;262(1-2):257-265.
-
(2001)
Gene.
, vol.262
, Issue.1-2
, pp. 257-265
-
-
Chiang, J.Y.1
Kimmel, R.2
Stroup, D.3
-
19
-
-
0037166261
-
Regulation of ATPbinding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors and
-
Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ. Regulation of ATPbinding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors and. J Biol Chem. 2002;277(21):18793-18800.
-
(2002)
J Biol Chem.
, vol.277
, Issue.21
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.5
Mangelsdorf, D.J.6
-
20
-
-
58049196754
-
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
-
Astapova I, Lee LJ, Morales C, Tauber S, Bilban M, Hollenberg AN. The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. Proc Natl Acad Sci U S A. 2008;105(49):19544-19549.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.49
, pp. 19544-19549
-
-
Astapova, I.1
Lee, L.J.2
Morales, C.3
Tauber, S.4
Bilban, M.5
Hollenberg, A.N.6
-
21
-
-
79951715829
-
The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis
-
Astapova I, et al. The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary- thyroid axis. Mol Endocrinol. 2011;25(2):212-224.
-
(2011)
Mol Endocrinol.
, vol.25
, Issue.2
, pp. 212-224
-
-
Astapova, I.1
-
22
-
-
0024356902
-
Time course of hepatic 3-hydroxy- 3-methylglutaryl coenzyme A reductase activity and messenger ribonucleic acid, biliary lipid secretion, and hepatic cholesterol content in methimazole- treated hypothyroid and hypophysectomized rats after triiodothyronine administration: Possible linkage of cholesterol synthesis to biliary secretion
-
Day R, et al. Time course of hepatic 3-hydroxy- 3-methylglutaryl coenzyme A reductase activity and messenger ribonucleic acid, biliary lipid secretion, and hepatic cholesterol content in methimazole- treated hypothyroid and hypophysectomized rats after triiodothyronine administration: possible linkage of cholesterol synthesis to biliary secretion. Endocrinology. 1989;125(1):459-468.
-
(1989)
Endocrinology.
, vol.125
, Issue.1
, pp. 459-468
-
-
Day, R.1
-
23
-
-
2342584091
-
Intracerebroventricular leptin regulates hepatic cholesterol metabolism
-
Vanpatten S, Karkanias GB, Rossetti L, Cohen DE. Intracerebroventricular leptin regulates hepatic cholesterol metabolism. Biochem J. 2004; 379(pt 2):229-233.
-
(2004)
Biochem J.
, vol.379
, Issue.PART 2
, pp. 229-233
-
-
Vanpatten, S.1
Karkanias, G.B.2
Rossetti, L.3
Cohen, D.E.4
-
24
-
-
67650092919
-
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
-
Zelcer N, Hong C, Boyadjian R, Tontonoz P. LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor. Science. 2009;325(5936):100-104.
-
(2009)
Science.
, vol.325
, Issue.5936
, pp. 100-104
-
-
Zelcer, N.1
Hong, C.2
Boyadjian, R.3
Tontonoz, P.4
-
25
-
-
0038614979
-
Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8
-
Yu L, York J, von Bergmann K, Lutjohann D, Cohen JC, Hobbs HH. Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8. J Biol Chem. 2003;278(18):15565- 15570.
-
(2003)
J Biol Chem.
, vol.278
, Issue.18
, pp. 15565-15570
-
-
Yu, L.1
York, J.2
Von Bergmann, K.3
Lutjohann, D.4
Cohen, J.C.5
Hobbs, H.H.6
-
26
-
-
0028157731
-
Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster
-
Turley SD, Herndon MW, Dietschy JM. Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. J Lipid Res. 1994;35(2):328-339.
-
(1994)
J Lipid Res.
, vol.35
, Issue.2
, pp. 328-339
-
-
Turley, S.D.1
Herndon, M.W.2
Dietschy, J.M.3
-
27
-
-
0041912965
-
Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: An analysis of direct versus indirect methodologies
-
Wang DQ, Carey MC. Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies. J Lipid Res. 2003;44(5):1042-1059.
-
(2003)
J Lipid Res.
, vol.44
, Issue.5
, pp. 1042-1059
-
-
Wang, D.Q.1
Carey, M.C.2
-
28
-
-
0041965752
-
Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: Studies in the gallstonesusceptible mouse
-
Wang DQ, Tazuma S, Cohen DE, Carey MC. Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstonesusceptible mouse. Am J Physiol Gastrointest Liver Physiol. 2003;285(3):G494-G502.
-
(2003)
Am J Physiol Gastrointest Liver Physiol.
, vol.285
, Issue.3
-
-
Wang, D.Q.1
Tazuma, S.2
Cohen, D.E.3
Carey, M.C.4
-
30
-
-
0037072876
-
Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts
-
Hyogo H, Roy S, Paigen B, Cohen DE. Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts. J Biol Chem. 2002;277(37):34117-34124.
-
(2002)
J Biol Chem.
, vol.277
, Issue.37
, pp. 34117-34124
-
-
Hyogo, H.1
Roy, S.2
Paigen, B.3
Cohen, D.E.4
-
31
-
-
0032913495
-
Thyroid hormone suppresses hepatic sterol 12-hydroxylase (CYP8B1) activity and messenger ribonucleic acid in rat liver: Failure to define known thyroid hormone response elements in the gene
-
Andersson U, Yang YZ, Bjorkhem I, Einarsson C, Eggertsen G, Gafvels M. Thyroid hormone suppresses hepatic sterol 12-hydroxylase (CYP8B1) activity and messenger ribonucleic acid in rat liver: failure to define known thyroid hormone response elements in the gene. Biochim Biophys Acta. 1999;1438(2):167-174.
-
(1999)
Biochim Biophys Acta.
, vol.1438
, Issue.2
, pp. 167-174
-
-
Andersson, U.1
Yang, Y.Z.2
Bjorkhem, I.3
Einarsson, C.4
Eggertsen, G.5
Gafvels, M.6
-
32
-
-
78149353724
-
Abolished synthesis of cholic acid reduces atherosclerotic development in apolipoprotein e knockout mice
-
Slatis K, et al. Abolished synthesis of cholic acid reduces atherosclerotic development in apolipoprotein E knockout mice. J Lipid Res. 2010;51(11):3289-3298.
-
(2010)
J Lipid Res.
, vol.51
, Issue.11
, pp. 3289-3298
-
-
Slatis, K.1
-
33
-
-
0033613935
-
Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5-cholestane-3,7,12-triol in human liver microsomes
-
Furster C, Wikvall K. Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5-cholestane-3,7,12-triol in human liver microsomes. Biochim Biophys Acta. 1999;1437(1):46-52.
-
(1999)
Biochim Biophys Acta.
, vol.1437
, Issue.1
, pp. 46-52
-
-
Furster, C.1
Wikvall, K.2
-
34
-
-
79960671360
-
Cholesterol 25-hydroxylation activity of CYP3A
-
Honda A, et al. Cholesterol 25-hydroxylation activity of CYP3A. J Lipid Res. 2011;52(8):1509-1516.
-
(2011)
J Lipid Res.
, vol.52
, Issue.8
, pp. 1509-1516
-
-
Honda, A.1
-
35
-
-
23244432637
-
LXR deficiency and cholesterol feeding affect the expression and phenobarbitalmediated induction of cytochromes P450 in mouse liver
-
Gnerre C, et al. LXR deficiency and cholesterol feeding affect the expression and phenobarbitalmediated induction of cytochromes P450 in mouse liver. J Lipid Res. 2005;46(8):1633-1642.
-
(2005)
J Lipid Res.
, vol.46
, Issue.8
, pp. 1633-1642
-
-
Gnerre, C.1
-
36
-
-
84455188475
-
Identical gene regulation patterns of T3 and selective thyroid hormone receptor modulator GC-1
-
Yuan C, et al. Identical gene regulation patterns of T3 and selective thyroid hormone receptor modulator GC-1. Endocrinology. 2012;153(1):501-511.
-
(2012)
Endocrinology.
, vol.153
, Issue.1
, pp. 501-511
-
-
Yuan, C.1
-
37
-
-
84865068640
-
Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice
-
Park YJ, Lee EK, Lee YK, Park do J, Jang HC, Moore DD. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice. Toxicol Appl Pharmacol. 2012;263(2):131-137.
-
(2012)
Toxicol Appl Pharmacol.
, vol.263
, Issue.2
, pp. 131-137
-
-
Park, Y.J.1
Lee, E.K.2
Lee, Y.K.3
Park Do, J.4
Jang, H.C.5
Moore, D.D.6
-
38
-
-
58149250221
-
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR)
-
Hernandez JP, Mota LC, Huang W, Moore DD, Baldwin WS. Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). Toxicology. 2009;256(1-2):53-64.
-
(2009)
Toxicology.
, vol.256
, Issue.1-2
, pp. 53-64
-
-
Hernandez, J.P.1
Mota, L.C.2
Huang, W.3
Moore, D.D.4
Baldwin, W.S.5
-
39
-
-
0035800772
-
Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
-
Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J Biol Chem. 2001;276(31):28857-28865.
-
(2001)
J Biol Chem.
, vol.276
, Issue.31
, pp. 28857-28865
-
-
Ananthanarayanan, M.1
Balasubramanian, N.2
Makishima, M.3
Mangelsdorf, D.J.4
Suchy, F.J.5
-
40
-
-
24144490445
-
LXRs regulate the balance between fat storage and oxidation
-
Kalaany NY, et al. LXRs regulate the balance between fat storage and oxidation. Cell Metab. 2005;1(4):231-244.
-
(2005)
Cell Metab.
, vol.1
, Issue.4
, pp. 231-244
-
-
Kalaany, N.Y.1
-
41
-
-
84892660787
-
Novel mechanism of positive versus negative regulation by thyroid hormone receptor 1 (TR1) identified by genome-wide profiling of binding sites in mouse liver
-
Ramadoss P, et al. Novel mechanism of positive versus negative regulation by thyroid hormone receptor 1 (TR1) identified by genome-wide profiling of binding sites in mouse liver. J Biol Chem. 2014;289(3):1313-1328.
-
(2014)
J Biol Chem.
, vol.289
, Issue.3
, pp. 1313-1328
-
-
Ramadoss, P.1
-
42
-
-
79952529158
-
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
-
Feng D, et al. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science. 2011;331(6022):1315-1319.
-
(2011)
Science.
, vol.331
, Issue.6022
, pp. 1315-1319
-
-
Feng, D.1
-
43
-
-
0001611155
-
Blood cholesterol values in hyperthyroidism and hypothyroidism - their significance
-
Mason RL, Hunt HM, Hurxthal L. Blood cholesterol values in hyperthyroidism and hypothyroidism - their significance. N Engl J Med. 1930;203(26):1273-1277.
-
(1930)
N Engl J Med.
, vol.203
, Issue.26
, pp. 1273-1277
-
-
Mason, R.L.1
Hunt, H.M.2
Hurxthal, L.3
-
44
-
-
78650911273
-
Cellular energy depletion resets whole-body energy by promoting coactivatormediated dietary fuel absorption
-
Chopra AR, et al. Cellular energy depletion resets whole-body energy by promoting coactivatormediated dietary fuel absorption. Cell Metab. 2011;13(1):35-43.
-
(2011)
Cell Metab.
, vol.13
, Issue.1
, pp. 35-43
-
-
Chopra, A.R.1
-
45
-
-
81055125669
-
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function
-
Yamamoto H, et al. NCoR1 is a conserved physiological modulator of muscle mass and oxidative function. Cell. 2011;147(4):827-839.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 827-839
-
-
Yamamoto, H.1
-
46
-
-
81055144760
-
Adipocyte NCoR knockout decreases PPAR phosphorylation and enhances PPAR activity and insulin sensitivity
-
Li P, et al. Adipocyte NCoR knockout decreases PPAR phosphorylation and enhances PPAR activity and insulin sensitivity. Cell. 2011;147(4):815-826.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 815-826
-
-
Li, P.1
-
47
-
-
0043133791
-
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression
-
Wagner BL, et al. Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol. 2003;23(16):5780-5789.
-
(2003)
Mol Cell Biol.
, vol.23
, Issue.16
, pp. 5780-5789
-
-
Wagner, B.L.1
-
49
-
-
0025914556
-
Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis
-
Cali JJ, Hsieh CL, Francke U, Russell DW. Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. J Biol Chem. 1991;266(12):7779-7783.
-
(1991)
J Biol Chem.
, vol.266
, Issue.12
, pp. 7779-7783
-
-
Cali, J.J.1
Hsieh, C.L.2
Francke, U.3
Russell, D.W.4
-
50
-
-
0032511035
-
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene
-
Rosen H, et al. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J Biol Chem. 1998; 273(24):14805-14812.
-
(1998)
J Biol Chem.
, vol.273
, Issue.24
, pp. 14805-14812
-
-
Rosen, H.1
-
51
-
-
0034671509
-
Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia
-
Repa JJ, et al. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J Biol Chem. 2000;275(50):39685-39692.
-
(2000)
Reversal by Cholic Acid Feeding. J Biol Chem.
, vol.275
, Issue.50
, pp. 39685-39692
-
-
Repa, J.J.1
-
52
-
-
19944427358
-
Role of CYP27A in cholesterol and bile acid metabolism
-
Dubrac S, et al. Role of CYP27A in cholesterol and bile acid metabolism. J Lipid Res. 2005;46(1):76-85.
-
(2005)
J Lipid Res.
, vol.46
, Issue.1
, pp. 76-85
-
-
Dubrac, S.1
-
53
-
-
0037072799
-
Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis
-
Meir K, et al. Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. J Biol Chem. 2002;277(37):34036-34041.
-
(2002)
J Biol Chem.
, vol.277
, Issue.37
, pp. 34036-34041
-
-
Meir, K.1
-
54
-
-
78651309475
-
Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver
-
Inoue S, Yoshinari K, Sugawara M, Yamazoe Y. Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver. Mol Pharmacol. 2011;79(1):148-156.
-
(2011)
Mol Pharmacol.
, vol.79
, Issue.1
, pp. 148-156
-
-
Inoue, S.1
Yoshinari, K.2
Sugawara, M.3
Yamazoe, Y.4
-
55
-
-
17344366172
-
A gene encoding a liverspecific ABC transporter is mutated in progressive familial intrahepatic cholestasis
-
Strautnieks SS, et al. A gene encoding a liverspecific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat Genet. 1998;20(3):233-238.
-
(1998)
Nat Genet.
, vol.20
, Issue.3
, pp. 233-238
-
-
Strautnieks, S.S.1
-
56
-
-
0035852720
-
Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis
-
Wang R, et al. Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. Proc Natl Acad Sci U S A. 2001;98(4):2011-2016.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, Issue.4
, pp. 2011-2016
-
-
Wang, R.1
-
57
-
-
9144241623
-
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis
-
Figge A, et al. Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. J Biol Chem. 2004; 279(4):2790-2799.
-
(2004)
J Biol Chem.
, vol.279
, Issue.4
, pp. 2790-2799
-
-
Figge, A.1
-
58
-
-
20144386690
-
A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse
-
Roy S, et al. A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse. Hepatology. 2005; 41(4):887-895.
-
(2005)
Hepatology.
, vol.41
, Issue.4
, pp. 887-895
-
-
Roy, S.1
-
59
-
-
0034891367
-
Impaired biliary lipid secretion in obese Zucker rats: Leptin promotes hepatic cholesterol clearance
-
VanPatten S, Ranginani N, Shefer S, Nguyen LB, Rossetti L, Cohen DE. Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance. Am J Physiol Gastrointest Liver Physiol. 2001;281(2):G393-G404.
-
(2001)
Am J Physiol Gastrointest Liver Physiol.
, vol.281
, Issue.2
-
-
Vanpatten, S.1
Ranginani, N.2
Shefer, S.3
Nguyen, L.B.4
Rossetti, L.5
Cohen, D.E.6
-
60
-
-
34547652884
-
Ligand activation of LXR reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR and apoE
-
Bradley MN, et al. Ligand activation of LXR reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR and apoE. J Clin Invest. 2007;117(8):2337-2346.
-
(2007)
J Clin Invest.
, vol.117
, Issue.8
, pp. 2337-2346
-
-
Bradley, M.N.1
-
61
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226(1):497-509.
-
(1957)
J Biol Chem.
, vol.226
, Issue.1
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
62
-
-
0024574432
-
An improved procedure for bile acid extraction and purification and tissue distribution in the rat
-
Locket PL, Gallaher DD. An improved procedure for bile acid extraction and purification and tissue distribution in the rat. Lipids. 1989;24(3):221-223.
-
(1989)
Lipids.
, vol.24
, Issue.3
, pp. 221-223
-
-
Locket, P.L.1
Gallaher, D.D.2
-
63
-
-
0024318186
-
Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions
-
Heuman DM. Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions. J Lipid Res. 1989;30(5):719-730.
-
(1989)
J Lipid Res.
, vol.30
, Issue.5
, pp. 719-730
-
-
Heuman, D.M.1
-
64
-
-
65649152582
-
Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis
-
Bhatnagar S, Damron HA, Hillgartner FB. Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis. J Biol Chem. 2009;284(15):10023-10033.
-
(2009)
J Biol Chem.
, vol.284
, Issue.15
, pp. 10023-10033
-
-
Bhatnagar, S.1
Damron, H.A.2
Hillgartner, F.B.3
|