Sonic hedgehog activation is implicated in diosgenin-induced megakaryocytic differentiation of human erythroleukemia cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Ghezali, Lamia ^a   Liagre, Bertrand ^a   Limami, Youness ^a   Beneytout, Jean Louis ^a   Leger, David Yannick ^a  

^a UNIVERSITÉ DE LIMOGES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIOSGENIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; G PROTEIN COUPLED RECEPTOR; GANT 61; GLI1 PROTEIN, HUMAN; MAPK1 PROTEIN, HUMAN; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SHH PROTEIN, HUMAN; SMO PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SYNTHESIS; ERYTHROLEUKEMIA CELL; GENE SEQUENCE; GENE SILENCING; HUMAN; HUMAN CELL; MEGAKARYOCYTE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; DRUG EFFECTS; ERYTHROLEUKEMIA; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; DIOSGENIN; GENE EXPRESSION REGULATION, LEUKEMIC; HEDGEHOG PROTEINS; HUMANS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MEGAKARYOCYTES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PYRIDINES; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84899710930     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095016     Document Type: Article

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