Cyclopamine induces eosinophilic differentiation and upregulates CD44 expression in myeloid leukemia cells

Leukemia Research

Volumn 35, Issue 5, 2011, Pages 638-645

  Takahashi, Tsutomu ^a   Kawakami, Koshi ^a   Mishima, Seiji ^a   Akimoto, Miho ^a   Takenaga, Keizo ^a   Suzumiya, Junji ^a   Honma, Yoshio ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

CD44; Cyclopamine; Differentiation; Eosinophil; Luxol fast blue staining; Myeloid leukemia cell

Indexed keywords

CYCLOPAMINE; HERMES ANTIGEN;

ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; EOSINOPHIL; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; MORPHOLOGY; MYELOID LEUKEMIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD44; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EOSINOPHILS; GENE EXPRESSION REGULATION, LEUKEMIC; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID; TUMOR CELLS, CULTURED; UP-REGULATION; VERATRUM ALKALOIDS;

EID: 79954569793     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.09.022     Document Type: Article

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