메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER; CYTOCHROME P450; DOCOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; OMEGA 3 LYSOPHOSPHOSPHOLIPID; OMEGA 6 FATTY ACID; PHOSPHOLIPID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FAT INTAKE; LIPID;

EID: 84899705280     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096221     Document Type: Article
Times cited : (33)

References (72)
  • 1
    • 79955455705 scopus 로고    scopus 로고
    • Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century
    • Blasbalg TL, Hibbeln JR, Ramsden CE, Majchrzak SF, Rawlings RR (2011) Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. Am J Clin Nutr 93: 950-962.
    • (2011) Am J Clin Nutr , vol.93 , pp. 950-962
    • Blasbalg, T.L.1    Hibbeln, J.R.2    Ramsden, C.E.3    Majchrzak, S.F.4    Rawlings, R.R.5
  • 3
    • 80052052129 scopus 로고    scopus 로고
    • The omega-6/omega-3 fatty acid ratio in chronic diseases: Animal models and molecular aspects
    • Kang JX (2011) The omega-6/omega-3 fatty acid ratio in chronic diseases: animal models and molecular aspects. World Rev Nutr Diet 102: 22-29.
    • (2011) World Rev Nutr Diet , vol.102 , pp. 22-29
    • Kang, J.X.1
  • 4
    • 84876342098 scopus 로고    scopus 로고
    • The omega-6/omega-3 ratio and dementia or cognitive decline: A systematic review on human studies and biological evidence
    • Loef M, Walach H (2013) The omega-6/omega-3 ratio and dementia or cognitive decline: a systematic review on human studies and biological evidence. J Nutr Gerontol Geriatr 32: 1-23.
    • (2013) J Nutr Gerontol Geriatr , vol.32 , pp. 1-23
    • Loef, M.1    Walach, H.2
  • 5
    • 46449123205 scopus 로고    scopus 로고
    • The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
    • Maywood
    • Simopoulos AP (2008) The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood) 233: 674-688.
    • (2008) Exp Biol Med , vol.233 , pp. 674-688
    • Simopoulos, A.P.1
  • 6
    • 33750284280 scopus 로고    scopus 로고
    • Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: Nutritional implications for chronic diseases
    • Simopoulos AP (2006) Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomed Pharmacother 60: 502-507.
    • (2006) Biomed Pharmacother , vol.60 , pp. 502-507
    • Simopoulos, A.P.1
  • 7
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang D, Dubois RN (2010) Eicosanoids and cancer. Nat Rev Cancer 10: 181-193.
    • (2010) Nat Rev Cancer , vol.10 , pp. 181-193
    • Wang, D.1    Dubois, R.N.2
  • 8
    • 77953806861 scopus 로고    scopus 로고
    • Low omega-6/omega-3 polyunsaturated fatty acid ratios reduce hepatic C-reactive protein expression in apolipoprotein E-null mice
    • Zhang L, Geng Y, Yin M, Mao L, Zhang S, et al. (2010) Low omega-6/omega-3 polyunsaturated fatty acid ratios reduce hepatic C-reactive protein expression in apolipoprotein E-null mice. Nutrition 26: 829-834.
    • (2010) Nutrition , vol.26 , pp. 829-834
    • Zhang, L.1    Geng, Y.2    Yin, M.3    Mao, L.4    Zhang, S.5
  • 9
    • 84861206960 scopus 로고    scopus 로고
    • New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids
    • de Lorgeril M, Salen P (2012) New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids. BMC Med 10: 50.
    • (2012) BMC Med , vol.10 , pp. 50
    • De Lorgeril, M.1    Salen, P.2
  • 10
    • 84855759607 scopus 로고    scopus 로고
    • The effects of long-term omega-3 fatty acid supplementation on cognition and Alzheimer's pathology in animal models of Alzheimer's disease: A systematic review and meta-analysis
    • Hooijmans CR, Pasker-de Jong PC, de Vries RB, Ritskes-Hoitinga M (2012) The effects of long-term omega-3 fatty acid supplementation on cognition and Alzheimer's pathology in animal models of Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis 28: 191-209.
    • (2012) J Alzheimers Dis , vol.28 , pp. 191-209
    • Hooijmans, C.R.1    Pasker-de Jong, P.C.2    De Vries, R.B.3    Ritskes-Hoitinga, M.4
  • 11
    • 84885979109 scopus 로고    scopus 로고
    • Novel n-3 immunoresolvents: Structures and actions
    • Dalli J, Colas RA, Serhan CN (2013) Novel n-3 immunoresolvents: structures and actions. Sci Rep 3: 1940.
    • (2013) Sci Rep , vol.3 , pp. 1940
    • Dalli, J.1    Colas, R.A.2    Serhan, C.N.3
  • 12
    • 56749173382 scopus 로고    scopus 로고
    • Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators
    • Serhan CN (2008) Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators. Prostaglandins Leukot Essent Fatty Acids 79: 157-163.
    • (2008) Prostaglandins Leukot Essent Fatty Acids , vol.79 , pp. 157-163
    • Serhan, C.N.1
  • 13
    • 0023778952 scopus 로고
    • Lipoxins: A new series of eicosanoids (biosynthesis, stereochemistry, and biological activities)
    • Serhan CN, Samuelsson B (1988) Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities). Adv Exp Med Biol 229: 1-14.
    • (1988) Adv Exp Med Biol , vol.229 , pp. 1-14
    • Serhan, C.N.1    Samuelsson, B.2
  • 14
    • 84886239681 scopus 로고    scopus 로고
    • Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids
    • Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, et al. (2013) Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One 8: e76575.
    • (2013) PLoS One , vol.8
    • Nording, M.L.1    Yang, J.2    Georgi, K.3    Hegedus Karbowski, C.4    German, J.B.5
  • 15
    • 1142310943 scopus 로고    scopus 로고
    • Fat-1 mice convert n-6 to n-3 fatty acids
    • DOI 10.1038/427504a
    • Kang JX, Wang J, Wu L, Kang ZB (2004) Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids. Nature 427: 504. (Pubitemid 38209102)
    • (2004) Nature , vol.427 , Issue.6974 , pp. 504
    • Kang, J.X.1    Wang, J.2    Wu, L.3    Kang, Z.B.4
  • 16
    • 77953288863 scopus 로고    scopus 로고
    • The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding
    • Orr SK, Tong JY, Kang JX, Ma DW, Bazinet RP (2010) The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding. Neurochem Res 35: 811-819.
    • (2010) Neurochem Res , vol.35 , pp. 811-819
    • Orr, S.K.1    Tong, J.Y.2    Kang, J.X.3    Ma, D.W.4    Bazinet, R.P.5
  • 17
    • 18144454187 scopus 로고    scopus 로고
    • A simplified method for analysis of polyunsaturated fatty acids
    • Kang JX, Wang J (2005) A simplified method for analysis of polyunsaturated fatty acids. BMC Biochem 6: 5.
    • (2005) BMC Biochem , vol.6 , pp. 5
    • Kang, J.X.1    Wang, J.2
  • 18
    • 84865494571 scopus 로고    scopus 로고
    • Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: Application in cardiac surgery
    • Strassburg K, Huijbrechts AM, Kortekaas KA, Lindeman JH, Pedersen TL, et al. (2012) Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery. Anal Bioanal Chem 404: 1413-1426.
    • (2012) Anal Bioanal Chem , vol.404 , pp. 1413-1426
    • Strassburg, K.1    Huijbrechts, A.M.2    Kortekaas, K.A.3    Lindeman, J.H.4    Pedersen, T.L.5
  • 22
    • 36649010249 scopus 로고    scopus 로고
    • Fat-1 transgenic mice: A new model for omega-3 research
    • Kang JX (2007) Fat-1 transgenic mice: a new model for omega-3 research. Prostaglandins Leukot Essent Fatty Acids 77: 263-267.
    • (2007) Prostaglandins Leukot Essent Fatty Acids , vol.77 , pp. 263-267
    • Kang, J.X.1
  • 23
    • 84896692369 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated Fatty acids alter the Fatty Acid composition of hepatic and plasma bioactive lipids in C57BL/6 mice: A lipidomic approach
    • Balogun KA, Albert CJ, Ford DA, Brown RJ, Cheema SK (2013) Dietary omega-3 polyunsaturated Fatty acids alter the Fatty Acid composition of hepatic and plasma bioactive lipids in C57BL/6 mice: a lipidomic approach. PLoS One 8: e82399.
    • (2013) PLoS One , vol.8
    • Balogun, K.A.1    Albert, C.J.2    Ford, D.A.3    Brown, R.J.4    Cheema, S.K.5
  • 25
    • 0030711745 scopus 로고    scopus 로고
    • Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: An 18-month controlled study
    • Katan MB, Deslypere JP, van Birgelen AP, Penders M, Zegwaard M (1997) Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study. J Lipid Res 38: 2012-2022. (Pubitemid 27468010)
    • (1997) Journal of Lipid Research , vol.38 , Issue.10 , pp. 2012-2022
    • Katan, M.B.1    Deslypere, J.P.2    Van Birgelen, A.P.J.M.3    Penders, M.4    Zegwaard, M.5
  • 26
    • 0027205413 scopus 로고
    • Incorporation of dietary n-3 fatty acids into molecular species of phosphatidyl choline and cholesteryl ester in normal human plasma
    • Subbaiah PV, Kaufman D, Bagdade JD (1993) Incorporation of dietary n-3 fatty acids into molecular species of phosphatidyl choline and cholesteryl ester in normal human plasma. Am J Clin Nutr 58: 360-368. (Pubitemid 23261966)
    • (1993) American Journal of Clinical Nutrition , vol.58 , Issue.3 , pp. 360-368
    • Subbaiah, P.V.1    Kaufman, D.2    Bagdade, J.D.3
  • 27
    • 0030892151 scopus 로고    scopus 로고
    • Relation of plasma phospholipid and cholesterol ester fatty acid composition to carotid artery intima-media thickness: The Atherosclerosis Risk in Communities (ARIC) Study
    • Ma J, Folsom AR, Lewis L, Eckfeldt JH (1997) Relation of plasma phospholipid and cholesterol ester fatty acid composition to carotid artery intima-media thickness: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Clin Nutr 65: 551-559. (Pubitemid 27130766)
    • (1997) American Journal of Clinical Nutrition , vol.65 , Issue.2 , pp. 551-559
    • Ma, J.1    Folsom, A.R.2    Lewis, L.3    Eckfeldt, J.H.4
  • 28
    • 84865477877 scopus 로고    scopus 로고
    • Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects
    • Ottestad I, Hassani S, Borge GI, Kohler A, Vogt G, et al. (2012) Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects. PLoS One 7: e42550.
    • (2012) PLoS One , vol.7
    • Ottestad, I.1    Hassani, S.2    Borge, G.I.3    Kohler, A.4    Vogt, G.5
  • 29
  • 32
    • 0030469761 scopus 로고    scopus 로고
    • Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects
    • Conquer JA, Holub BJ (1996) Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects. J Nutr 126: 3032-3039. (Pubitemid 27023877)
    • (1996) Journal of Nutrition , vol.126 , Issue.12 , pp. 3032-3039
    • Conquer, J.A.1    Holub, B.J.2
  • 33
    • 0030937209 scopus 로고    scopus 로고
    • Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores
    • DOI 10.1007/s11745-997-0043-y
    • Conquer JA, Holub BJ (1997) Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores. Lipids 32: 341-345. (Pubitemid 27131769)
    • (1997) Lipids , vol.32 , Issue.3 , pp. 341-345
    • Conquer, J.A.1    Holub, B.J.2
  • 34
    • 0026060744 scopus 로고
    • Peroxisomal retroconversion of docosahexaenoic acid (22:6(n-3)) to eicosapentaenoic acid (20:5(n-3)) studied in isolated rat liver cells
    • Gronn M, Christensen E, Hagve TA, Christophersen BO (1991) Peroxisomal retroconversion of docosahexaenoic acid (22:6(n-3)) to eicosapentaenoic acid (20:5(n-3)) studied in isolated rat liver cells. Biochim Biophys Acta 1081: 85-91.
    • (1991) Biochim Biophys Acta , vol.1081 , pp. 85-91
    • Gronn, M.1    Christensen, E.2    Hagve, T.A.3    Christophersen, B.O.4
  • 35
    • 2442445051 scopus 로고    scopus 로고
    • Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy
    • Stark KD, Holub BJ (2004) Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. Am J Clin Nutr 79: 765-773. (Pubitemid 41103876)
    • (2004) American Journal of Clinical Nutrition , vol.79 , Issue.5 , pp. 765-773
    • Stark, K.D.1    Holub, B.J.2
  • 36
    • 0022338088 scopus 로고
    • Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans
    • von Schacky C, Weber PC (1985) Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans. J Clin Invest 76: 2446-2450.
    • (1985) J Clin Invest , vol.76 , pp. 2446-2450
    • Von Schacky, C.1    Weber, P.C.2
  • 37
    • 84877898340 scopus 로고    scopus 로고
    • Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets
    • Bruins MJ, Dane AD, Strassburg K, Vreeken RJ, Newman JW, et al. (2013) Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets. J Lipid Res 54: 1598-1607.
    • (2013) J Lipid Res , vol.54 , pp. 1598-1607
    • Bruins, M.J.1    Dane, A.D.2    Strassburg, K.3    Vreeken, R.J.4    Newman, J.W.5
  • 38
    • 0024546674 scopus 로고
    • The reactivity of plasma phospholipids with lecithin:cholesterol acyltransferase is decreased in fish oil-fed monkeys
    • Parks JS, Bullock BC, Rudel LL (1989) The reactivity of plasma phospholipids with lecithin:cholesterol acyltransferase is decreased in fish oil-fed monkeys. J Biol Chem 264: 2545-2551. (Pubitemid 19057742)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.5 , pp. 2545-2551
    • Parks, J.S.1    Bullock, B.C.2    Rudel, L.L.3
  • 39
    • 0028817149 scopus 로고
    • Dietary fatty acid modification of HDL phospholipid molecular species alters lecithin: Cholesterol acyltransferase reactivity in cynomolgus monkeys
    • Thornburg JT, Parks JS, Rudel LL (1995) Dietary fatty acid modification of HDL phospholipid molecular species alters lecithin: cholesterol acyltransferase reactivity in cynomolgus monkeys. J Lipid Res 36: 277-289.
    • (1995) J Lipid Res , vol.36 , pp. 277-289
    • Thornburg, J.T.1    Parks, J.S.2    Rudel, L.L.3
  • 40
    • 0023218989 scopus 로고
    • Alterations in molecular species of cholesterol esters formed via plasma lecithin-cholesterol acyltransferase in human subjects consuming fish oil
    • Holub BJ, Bakker DJ, Skeaff CM (1987) Alterations in molecular species of cholesterol esters formed via plasma lecithin-cholesterol acyltransferase in human subjects consuming fish oil. Atherosclerosis 66: 11-18. (Pubitemid 17109733)
    • (1987) Atherosclerosis , vol.66 , Issue.1-2 , pp. 11-18
    • Holub, B.J.1    Bakker, D.J.2    Skeaff, C.M.3
  • 41
    • 0026769840 scopus 로고
    • Inhibition of lecithin:Cholesterol acyltransferase activity by synthetic phosphatidylcholine species containing eicosapentaenoic acid or docosahexaenoic acid in the sn-2 position
    • Parks JS, Thuren TY, Schmitt JD (1992) Inhibition of lecithin:cholesterol acyltransferase activity by synthetic phosphatidylcholine species containing eicosapentaenoic acid or docosahexaenoic acid in the sn-2 position. J Lipid Res 33: 879-887.
    • (1992) J Lipid Res , vol.33 , pp. 879-887
    • Parks, J.S.1    Thuren, T.Y.2    Schmitt, J.D.3
  • 42
    • 0027021117 scopus 로고
    • Effects of purified eicosapentaenoic acid ethyl ester on plasma lipoproteins in primary hypercholesterolemia
    • Nozaki S, Matsuzawa Y, Hirano K, Sakai N, Kubo M, et al. (1992) Effects of purified eicosapentaenoic acid ethyl ester on plasma lipoproteins in primary hypercholesterolemia. Int J Vitam Nutr Res 62: 256-260.
    • (1992) Int J Vitam Nutr Res , vol.62 , pp. 256-260
    • Nozaki, S.1    Matsuzawa, Y.2    Hirano, K.3    Sakai, N.4    Kubo, M.5
  • 43
    • 71049173637 scopus 로고    scopus 로고
    • Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome
    • Satoh N, Shimatsu A, Kotani K, Himeno A, Majima T, et al. (2009) Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome. Hypertens Res 32: 1004-1008.
    • (2009) Hypertens Res , vol.32 , pp. 1004-1008
    • Satoh, N.1    Shimatsu, A.2    Kotani, K.3    Himeno, A.4    Majima, T.5
  • 45
    • 0034016538 scopus 로고    scopus 로고
    • Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hypedipidemic men
    • Mori TA, Burke V, Puddey IB, Watts GF, O'Neal DN, et al. (2000) Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men. Am J Clin Nutr 71: 1085-1094. (Pubitemid 30230554)
    • (2000) American Journal of Clinical Nutrition , vol.71 , Issue.5 , pp. 1085-1094
    • Mori, T.A.1    Burke, V.2    Puddey, I.B.3    Watts, G.F.4    O'Neal, D.N.5    Best, J.D.6    Beilin, L.J.7
  • 46
    • 0021169911 scopus 로고
    • Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet
    • Kobatake Y, Kuroda K, Jinnouchi H, Nishide E, Innami S (1984) Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet. J Nutr Sci Vitaminol (Tokyo) 30: 357-372. (Pubitemid 14012014)
    • (1984) Journal of Nutritional Science and Vitaminology , vol.30 , Issue.4 , pp. 357-372
    • Kobatake, Y.1    Kuroda, K.2    Jinnouchi, H.3
  • 47
    • 84856179128 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: A review
    • Jacobson TA, Glickstein SB, Rowe JD, Soni PN (2012) Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review. J Clin Lipidol 6: 5-18.
    • (2012) J Clin Lipidol , vol.6 , pp. 5-18
    • Jacobson, T.A.1    Glickstein, S.B.2    Rowe, J.D.3    Soni, P.N.4
  • 48
    • 0142059080 scopus 로고    scopus 로고
    • Docosahexaenoic acid: Membrane properties of a unique fatty acid
    • DOI 10.1016/S0009-3084(03)00101-4
    • Stillwell W, Wassall SR (2003) Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids 126: 1-27. (Pubitemid 37297962)
    • (2003) Chemistry and Physics of Lipids , vol.126 , Issue.1 , pp. 1-27
    • Stillwell, W.1    Wassall, S.R.2
  • 50
    • 0034912812 scopus 로고    scopus 로고
    • Lysophosphatidylcholine as a preferred carrier form of docosahexaenoic acid to the brain
    • discussion 215-221
    • Lagarde M, Bernoud N, Brossard N, Lemaitre-Delaunay D, Thies F, et al. (2001) Lysophosphatidylcholine as a preferred carrier form of docosahexaenoic acid to the brain. J Mol Neurosci 16: 201-204; discussion 215-221.
    • (2001) J Mol Neurosci , vol.16 , pp. 201-204
    • Lagarde, M.1    Bernoud, N.2    Brossard, N.3    Lemaitre-Delaunay, D.4    Thies, F.5
  • 51
    • 84899470675 scopus 로고    scopus 로고
    • Docosahexaenoic acid and its derivative neuroprotectin D1 display neuroprotective properties in the retina, brain and central nervous system
    • Bazan NG, Calandria JM, Gordon WC (2013) Docosahexaenoic acid and its derivative neuroprotectin D1 display neuroprotective properties in the retina, brain and central nervous system. Nestle Nutr Inst Workshop Ser 77: 121-131.
    • (2013) Nestle Nutr Inst Workshop Ser , vol.77 , pp. 121-131
    • Bazan, N.G.1    Calandria, J.M.2    Gordon, W.C.3
  • 53
    • 78650060401 scopus 로고    scopus 로고
    • Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice
    • White PJ, Arita M, Taguchi R, Kang JX, Marette A (2010) Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice. Diabetes 59: 3066-3073.
    • (2010) Diabetes , vol.59 , pp. 3066-3073
    • White, P.J.1    Arita, M.2    Taguchi, R.3    Kang, J.X.4    Marette, A.5
  • 54
    • 84890142204 scopus 로고    scopus 로고
    • Elevated tissue omega-3 fatty acid status prevents age-related glucose intolerance in fat-1 transgenic mice
    • Romanatto T, Fiamoncini J, Wang B, Curi R, Kang JX (2013) Elevated tissue omega-3 fatty acid status prevents age-related glucose intolerance in fat-1 transgenic mice. Biochim Biophys Acta 1842: 186-191.
    • (2013) Biochim Biophys Acta , vol.1842 , pp. 186-191
    • Romanatto, T.1    Fiamoncini, J.2    Wang, B.3    Curi, R.4    Kang, J.X.5
  • 55
    • 79953174254 scopus 로고    scopus 로고
    • High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: Inflammatory pathway inhibition
    • Bellenger J, Bellenger S, Bataille A, Massey KA, Nicolaou A, et al. (2011) High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition. Diabetes 60: 1090-1099.
    • (2011) Diabetes , vol.60 , pp. 1090-1099
    • Bellenger, J.1    Bellenger, S.2    Bataille, A.3    Massey, K.A.4    Nicolaou, A.5
  • 56
    • 84891737631 scopus 로고    scopus 로고
    • Molecular interplay between Delta5/Delta6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis
    • Lopez-Vicario C, Gonzalez-Periz A, Rius B, Moran-Salvador E, Garcia-Alonso V, et al. (2014) Molecular interplay between Delta5/Delta6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis. Gut 63: 344-355.
    • (2014) Gut , vol.63 , pp. 344-355
    • Lopez-Vicario, C.1    Gonzalez-Periz, A.2    Rius, B.3    Moran-Salvador, E.4    Garcia-Alonso, V.5
  • 57
    • 0035942156 scopus 로고    scopus 로고
    • Cholesterol sulfate: A new adhesive molecule for platelets
    • Merten M, Dong JF, Lopez JA, Thiagarajan P (2001) Cholesterol sulfate: a new adhesive molecule for platelets. Circulation 103: 2032-2034. (Pubitemid 32373002)
    • (2001) Circulation , vol.103 , Issue.16 , pp. 2032-2034
    • Merten, M.1    Dong, J.F.2    Lopez, J.A.3    Thiagarajan, P.4
  • 58
    • 43049170473 scopus 로고    scopus 로고
    • Docosahexaenoic acid domains: The ultimate non-raft membrane domain
    • Wassall SR, Stillwell W (2008) Docosahexaenoic acid domains: the ultimate non-raft membrane domain. Chem Phys Lipids 153: 57-63.
    • (2008) Chem Phys Lipids , vol.153 , pp. 57-63
    • Wassall, S.R.1    Stillwell, W.2
  • 59
    • 0032412509 scopus 로고    scopus 로고
    • Cholesterol versus cholesterol sulfate: Effects on properties of phospholipid bilayers containing docosahexaenoic acid
    • DOI 10.1016/S0009-3084(98)00065-6, PII S0009308498000656
    • Schofield M, Jenski LJ, Dumaual AC, Stillwell W (1998) Cholesterol versus cholesterol sulfate: effects on properties of phospholipid bilayers containing docosahexaenoic acid. Chem Phys Lipids 95: 23-36. (Pubitemid 29034716)
    • (1998) Chemistry and Physics of Lipids , vol.95 , Issue.1 , pp. 23-36
    • Schofield, M.1    Jenski, L.J.2    Dumaual, A.C.3    Stillwell, W.4
  • 60
    • 84872254688 scopus 로고    scopus 로고
    • Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health
    • Morisseau C, Hammock BD (2013) Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol 53: 37-58.
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 37-58
    • Morisseau, C.1    Hammock, B.D.2
  • 61
    • 77955689624 scopus 로고    scopus 로고
    • Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters
    • Shearer GC, Harris WS, Pedersen TL, Newman JW (2010) Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res 51: 2074-2081.
    • (2010) J Lipid Res , vol.51 , pp. 2074-2081
    • Shearer, G.C.1    Harris, W.S.2    Pedersen, T.L.3    Newman, J.W.4
  • 63
    • 84863792296 scopus 로고    scopus 로고
    • Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers
    • Keenan AH, Pedersen TL, Fillaus K, Larson MK, Shearer GC, et al. (2012) Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers. J Lipid Res 53: 1662-1669.
    • (2012) J Lipid Res , vol.53 , pp. 1662-1669
    • Keenan, A.H.1    Pedersen, T.L.2    Fillaus, K.3    Larson, M.K.4    Shearer, G.C.5
  • 64
    • 77958484254 scopus 로고    scopus 로고
    • Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids
    • Arnold C, Markovic M, Blossey K, Wallukat G, Fischer R, et al. (2010) Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem 285: 32720-32733.
    • (2010) J Biol Chem , vol.285 , pp. 32720-32733
    • Arnold, C.1    Markovic, M.2    Blossey, K.3    Wallukat, G.4    Fischer, R.5
  • 65
    • 18344400259 scopus 로고    scopus 로고
    • Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases
    • DOI 10.1016/S0090-6980(02)00038-2, PII S0090698002000382
    • Capdevila JH, Falck JR (2002) Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases. Prostaglandins Other Lipid Mediat 68-69: 325-344. (Pubitemid 35247405)
    • (2002) Prostaglandins and Other Lipid Mediators , vol.68-69 , pp. 325-344
    • Capdevila, J.H.1    Falck, J.R.2
  • 66
    • 66349109660 scopus 로고    scopus 로고
    • Arachidonic acid cytochrome P450 epoxygenase pathway
    • Spector AA (2009) Arachidonic acid cytochrome P450 epoxygenase pathway. J Lipid Res 50 Suppl: S52-56.
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Spector, A.A.1
  • 67
    • 0035965327 scopus 로고    scopus 로고
    • Epoxygenase pathways of arachidonic acid metabolism
    • Zeldin DC (2001) Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem 276: 36059-36062.
    • (2001) J Biol Chem , vol.276 , pp. 36059-36062
    • Zeldin, D.C.1
  • 68
    • 78149253514 scopus 로고    scopus 로고
    • 17,18-epoxyeicosatetraenoic acid targets PPARgamma and p38 mitogen-activated protein kinase to mediate its anti-inflammatory effects in the lung: Role of soluble epoxide hydrolase
    • Morin C, Sirois M, Echave V, Albadine R, Rousseau E (2010) 17,18-epoxyeicosatetraenoic acid targets PPARgamma and p38 mitogen-activated protein kinase to mediate its anti-inflammatory effects in the lung: role of soluble epoxide hydrolase. Am J Respir Cell Mol Biol 43: 564-575.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , pp. 564-575
    • Morin, C.1    Sirois, M.2    Echave, V.3    Albadine, R.4    Rousseau, E.5
  • 69
    • 78650051942 scopus 로고    scopus 로고
    • Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids
    • Morisseau C, Inceoglu B, Schmelzer K, Tsai HJ, Jinks SL, et al. (2010) Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res 51: 3481-3490.
    • (2010) J Lipid Res , vol.51 , pp. 3481-3490
    • Morisseau, C.1    Inceoglu, B.2    Schmelzer, K.3    Tsai, H.J.4    Jinks, S.L.5
  • 70
    • 0029021197 scopus 로고
    • Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis
    • VanRollins M (1995) Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis. J Pharmacol Exp Ther 274: 798-804.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 798-804
    • VanRollins, M.1
  • 72
    • 77954856325 scopus 로고    scopus 로고
    • Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids
    • Arnold C, Konkel A, Fischer R, Schunck WH (2010) Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids. Pharmacol Rep 62: 536-547.
    • (2010) Pharmacol Rep , vol.62 , pp. 536-547
    • Arnold, C.1    Konkel, A.2    Fischer, R.3    Schunck, W.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.