Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

Acta Neuropathologica

Volumn 122, Issue 2, 2011, Pages 231-240

  Northcott, Paul A ^a   Hielscher, Thomas ^b   Dubuc, Adrian ^a,c   MacK, Stephen ^a,c   Shih, David ^a,c   Remke, Marc ^b,d   Al Halabi, Hani ^e   Albrecht, Steffen ^f   Jabado, Nada ^g   Eberhart, Charles G ^h   Grajkowska, Wieslawa ⁱ   Weiss, William A ^j   Clifford, Steven C ^k   Bouffet, Eric ^a   Rutka, James T ^a,c   Korshunov, Andrey ^b   Pfister, Stefan ^b,d   Taylor, Michael D ^a,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e MONTREAL GENERAL HOSPITAL   (Canada)

^f MONTREAL CHILDREN S HOSPITAL   (Canada)

^g MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^h JOHNS HOPKINS UNIVERSITY   (United States)

ⁱ CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k NEWCASTLE UNIVERSITY   (United Kingdom)

more..

Author keywords

Genomics; Medulloblastoma; Molecular classification; Sonic hedgehog

Indexed keywords

CYCLIN DEPENDENT KINASE 6; MYC PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2;

ADULT; AGE DISTRIBUTION; ARTICLE; CANCER SURVIVAL; CHILD; CHROMOSOME 10Q; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CHROMOSOME GAIN; COHORT ANALYSIS; CONTROLLED STUDY; CYTOGENETICS; EXTRACELLULAR MATRIX; FEMALE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE LOCATION; GENETIC DATABASE; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; METASTASIS; NUCLEOTIDE SEQUENCE; ONCOGENE; ONCOGENE MYC; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; SHH GENE; SYNAPTOGENESIS; TISSUE MICROARRAY;

ADULT; AGE OF ONSET; CEREBELLAR NEOPLASMS; CHILD; CLUSTER ANALYSIS; FEMALE; HEDGEHOG PROTEINS; HUMANS; INFANT; MALE; MEDULLOBLASTOMA;

EID: 79960842253     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0846-7     Document Type: Article

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