-
1
-
-
34248584542
-
Treatment of newly diagnosed diffuse brain stem gliomas in children: In search of the holy grail
-
Korones DN: Treatment of newly diagnosed diffuse brain stem gliomas in children: In search of the holy grail. Expert Rev Anticancer Ther 7:663-674, 2007
-
(2007)
Expert Rev Anticancer Ther
, vol.7
, pp. 663-674
-
-
Korones, D.N.1
-
2
-
-
55949132115
-
Management of and prognosis with medulloblastoma: Therapy at a crossroads
-
Packer RJ, Vezina G: Management of and prognosis with medulloblastoma: Therapy at a crossroads. Arch Neurol 65:1419-1424, 2008
-
(2008)
Arch Neurol
, vol.65
, pp. 1419-1424
-
-
Packer, R.J.1
Vezina, G.2
-
3
-
-
22944436550
-
Treatment of medulloblastoma with postoperative chemotherapy alone: An SFOP prospective trial in young children
-
DOI 10.1016/S1470-2045(05)70252-7, PII S1470204505702527
-
Grill J, Sainte-Rose C, Jouvet A, et al: Treatment of medulloblastoma with postoperative chemotherapy alone: An SFOP prospective trial in young children. Lancet Oncol 6:573-580, 2005 (Pubitemid 41051935)
-
(2005)
Lancet Oncology
, vol.6
, Issue.8
, pp. 573-580
-
-
Grill, J.1
Sainte-Rose, C.2
Jouvet, A.3
Gentet, J.-C.4
Lejars, O.5
Frappaz, D.6
Doz, F.7
Rialland, X.8
Pichon, F.9
Bertozzi, A.-I.10
Chastagner, P.11
Couanet, D.12
Habrand, J.-L.13
Raquin, M.-A.14
Le, D.M.-C.15
Kalifa, C.16
-
4
-
-
20044371594
-
Treatment of early childhood medulloblastoma by postoperative chemotherapy alone
-
DOI 10.1056/NEJMoa042176
-
Rutkowski S, Bode U, Deinlein F, et al: Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med 352: 978-986, 2005 (Pubitemid 40349500)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 978-986
-
-
Rutkowski, S.1
Bode, U.2
Deinlein, F.3
Ottensmeier, H.4
Warmuth-Metz, M.5
Soerensen, N.6
Graf, N.7
Emser, A.8
Pietsch, T.9
Wolff, J.E.A.10
Kortmann, R.D.11
Kuehl, J.12
-
5
-
-
33749044182
-
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective, multicentre trial
-
DOI 10.1016/S1470-2045(06)70867-1, PII S1470204506708671
-
Gajjar A, Chintagumpala M, Ashley D, et al: Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective, multicentre trial. Lancet Oncol 7:813-820, 2006 (Pubitemid 44464063)
-
(2006)
Lancet Oncology
, vol.7
, Issue.10
, pp. 813-820
-
-
Gajjar, A.1
Chintagumpala, M.2
Ashley, D.3
Kellie, S.4
Kun, L.E.5
Merchant, T.E.6
Woo, S.7
Wheeler, G.8
Ahern, V.9
Krasin, M.J.10
Fouladi, M.11
Broniscer, A.12
Krance, R.13
Hale, G.A.14
Stewart, C.F.15
Dauser, R.16
Sanford, R.A.17
Fuller, C.18
Lau, C.19
Boyett, J.M.20
Wallace, D.21
Gilbertson, R.J.22
more..
-
6
-
-
33748660920
-
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma
-
DOI 10.1200/JCO.2006.06.4980
-
Packer RJ, Gajjar A, Vezina G, et al: Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol 24: 4202-4208, 2006 (Pubitemid 46622300)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.25
, pp. 4202-4208
-
-
Packer, R.J.1
Gajjar, A.2
Vezina, G.3
Rorke-Adams, L.4
Burger, P.C.5
Robertson, P.L.6
Bayer, L.7
LaFond, D.8
Donahue, B.R.9
Marymont, M.H.10
Muraszko, K.11
Langston, J.12
Sposto, R.13
-
7
-
-
0037604509
-
Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas
-
McManamy CS, Lamont JM, Taylor RE, et al: Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas. J Neuropathol Exp Neurol 62:627-632, 2003 (Pubitemid 36682635)
-
(2003)
Journal of Neuropathology and Experimental Neurology
, vol.62
, Issue.6
, pp. 627-632
-
-
McManamy, C.S.1
Lamont, J.M.2
Taylor, R.E.3
Cole, M.4
Pearson, A.D.J.5
Clifford, S.C.6
Ellison, D.W.7
-
8
-
-
33947521508
-
Nodule formation and desmoplasia in medulloblastomas - Defining the nodular/desmoplastic variant and its biological behavior
-
DOI 10.1111/j.1750-3639.2007.00058.x
-
McManamy CS, Pears J, Weston CL, et al: Nodule formation and desmoplasia in medulloblastomasdefining the nodular/desmoplastic variant and its biological behavior. Brain Pathol 17:151-164, 2007 (Pubitemid 46466135)
-
(2007)
Brain Pathology
, vol.17
, Issue.2
, pp. 151-164
-
-
McManamy, C.S.1
Pears, J.2
Weston, C.L.3
Hanzely, Z.4
Ironside, J.W.5
Taylor, R.E.6
Grundy, R.G.7
Clifford, S.C.8
Ellison, D.W.9
-
9
-
-
0033994659
-
TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors
-
Grotzer MA, Janss AJ, Fung K, et al: TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors. J Clin Oncol 18:1027-1035, 2000 (Pubitemid 30123779)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.5
, pp. 1027-1035
-
-
Grotzer, M.A.1
Janss, A.J.2
Fung, K.-M.3
Biegel, J.A.4
Sutton, L.N.5
Rorke, L.B.6
Zhao, H.7
Cnaan, A.8
Phillips, P.C.9
Lee, V.M.-Y.10
Trojanowski, J.Q.11
-
10
-
-
32944461274
-
Beta-catenin status predicts a favorable outcome in childhood medulloblastoma: The United Kingdom Children's Cancer Study Group Brain Tumour Committee
-
DOI 10.1200/JCO.2005.01.5479
-
Ellison DW, Onilude OE, Lindsey JC, et al: Beta-catenin status predicts a favorable outcome in childhood medulloblastoma: The United Kingdom Children's Cancer Study Group Brain Tumour Committee. J Clin Oncol 23:7951-7957, 2005 (Pubitemid 46657395)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 7951-7957
-
-
Ellison, D.W.1
Onilude, O.E.2
Lindsey, J.C.3
Lusher, M.E.4
Weston, C.L.5
Taylor, R.E.6
Pearson, A.D.7
Clifford, S.C.8
-
11
-
-
23044445753
-
Survivin is a negative prognostic marker in medulloblastoma
-
DOI 10.1111/j.1365-2990.2005.00664.x
-
Pizem J, Cort A, Zadravec-Zaletel L, et al: Survivin is a negative prognostic marker in medulloblastoma. Neuropathol Appl Neurobiol 31:422-428, 2005 (Pubitemid 41059863)
-
(2005)
Neuropathology and Applied Neurobiology
, vol.31
, Issue.4
, pp. 422-428
-
-
Pizem, J.1
Cor, A.2
Zadravec-Zaletel, L.3
Popovic, M.4
-
12
-
-
63749118521
-
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
-
Pfister S, Remke M, Benner A, et al: Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol 27:1627-1636, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 1627-1636
-
-
Pfister, S.1
Remke, M.2
Benner, A.3
-
13
-
-
9344240453
-
A clinicobiological model predicting survival in medulloblastoma
-
DOI 10.1158/1078-0432.CCR-04-0499
-
Ray A, Ho M, Ma J, et al: A clinicobiological model predicting survival in medulloblastoma. Clin Cancer Res 10:7613-7620, 2004 (Pubitemid 39557524)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.22
, pp. 7613-7620
-
-
Ray, A.1
Ho, M.2
Ma, J.3
Parkes, R.K.4
Mainprize, T.G.5
Ueda, S.6
McLaughlin, J.7
Bouffet, E.8
Rutka, J.T.9
Hawkins, C.E.10
-
14
-
-
33646362581
-
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
-
Thompson MC, Fuller C, Hogg TL, et al: Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol 24:1924-1931, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 1924-1931
-
-
Thompson, M.C.1
Fuller, C.2
Hogg, T.L.3
-
15
-
-
0035863498
-
Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched
-
Wetmore C, Eberhart DE, Curran T: Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched. Cancer Res 61:513-516, 2001 (Pubitemid 32128609)
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 513-516
-
-
Wetmore, C.1
Eberhart, D.E.2
Curran, T.3
-
16
-
-
60549111837
-
Biological background of pediatric medulloblastoma and ependymoma: A review from a translational research perspective
-
de Bont JM, Packer RJ, Michiels EM, et al: Biological background of pediatric medulloblastoma and ependymoma: A review from a translational research perspective. Neuro Oncol 10:1040-1060, 2008
-
(2008)
Neuro Oncol
, vol.10
, pp. 1040-1060
-
-
De Bont, J.M.1
Packer, R.J.2
Michiels, E.M.3
-
17
-
-
0034972938
-
Intense p53 staining is a valuable prognostic indicator for poor prognosis in medulloblastoma/central nervous system primitive neuroectodermal tumors
-
DOI 10.1023/A:1010691330670
-
Woodburn RT, Azzarelli B, Montebello JF, et al: Intense p53 staining is a valuable prognostic indicator for poor prognosis in medulloblastoma/central nervous system primitive neuroectodermal tumors. J Neurooncol 52:57-62, 2001 (Pubitemid 32544659)
-
(2001)
Journal of Neuro-Oncology
, vol.52
, Issue.1
, pp. 57-62
-
-
Woodburn, R.T.1
Azzarelli, B.2
Montebello, J.F.3
Goss, I.E.4
-
18
-
-
0037034253
-
Expression of p53 and prognosis in children with malignant gliomas
-
DOI 10.1056/NEJMoa012224
-
Pollack IF, Finkelstein SD, Woods J, et al: Expression of p53 and prognosis in children with malignant gliomas. N Engl J Med 346:420-427, 2002 (Pubitemid 34437697)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.6
, pp. 420-427
-
-
Pollack, I.F.1
Finkelstein, S.D.2
Woods, J.3
Burnham, J.4
Holmes, E.J.5
Hamilton, R.L.6
Yates, A.J.7
Boyett, J.M.8
Finlay, J.L.9
Sposto, R.10
-
19
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97-109, 2007
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
20
-
-
0037080303
-
Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study
-
DOI 10.1002/cncr.10189
-
Eberhart CG, Kepner JL, Goldthwaite PT, et al: Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study. Cancer 94:552-560, 2002 (Pubitemid 34081387)
-
(2002)
Cancer
, vol.94
, Issue.2
, pp. 552-560
-
-
Eberhart, C.G.1
Kepner, J.L.2
Goldthwaite, P.T.3
Kun, L.E.4
Duffner, P.K.5
Friedman, H.S.6
Strother, D.R.7
Burger, P.C.8
-
21
-
-
49649110984
-
Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome
-
Shlien A, Tabori U, Marshall CR, et al: Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome. Proc Natl Acad Sci U S A 105:11264-11269, 2008
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11264-11269
-
-
Shlien, A.1
Tabori, U.2
Marshall, C.R.3
-
22
-
-
0028172248
-
p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma
-
Adesina AM, Nalbantoglu J, Cavenee WK: p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 54:5649-5651, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5649-5651
-
-
Adesina, A.M.1
Nalbantoglu, J.2
Cavenee, W.K.3
-
24
-
-
1242351324
-
The TP53-ARF tumor suppressor pathway is frequently disrupted in large/ cell anaplastic medulloblastoma
-
DOI 10.1016/j.molbrainres.2003.11.016
-
Frank AJ, Hernan R, Hollander A, et al: The TP53-ARF tumor suppressor pathway is frequently disrupted in large/cell anaplastic medulloblastoma. Brain Res Mol Brain Res 121:137-140, 2004 (Pubitemid 38224178)
-
(2004)
Molecular Brain Research
, vol.121
, Issue.1-2
, pp. 137-140
-
-
Frank, A.J.1
Hernan, R.2
Hollander, A.3
Lindsey, J.C.4
Lusher, M.E.5
Fuller, C.E.6
Clifford, S.C.7
Gilbertson, R.J.8
-
25
-
-
0034794796
-
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease
-
DOI 10.1038/ng731
-
MacDonald TJ, Brown KM, LaFleur B, et al: Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nat Genet 29:143-152, 2001 (Pubitemid 32952650)
-
(2001)
Nature Genetics
, vol.29
, Issue.2
, pp. 143-152
-
-
MacDonald, T.J.1
Brown, K.M.2
Lafleur, B.3
Peterson, K.4
Lawlor, C.5
Chen, Y.6
Packer, R.J.7
Cogen, P.8
Stephan, D.A.9
-
26
-
-
0032564351
-
The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression
-
Shu HK, Kim MM, Chen P, et al: The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression. Proc Natl Acad Sci U S A 95:14453-14458, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14453-14458
-
-
Shu, H.K.1
Kim, M.M.2
Chen, P.3
-
27
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068, 2008
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
28
-
-
0035445646
-
Clinical and molecular stratification of disease risk in medulloblastoma
-
DOI 10.1054/bjoc.2001.1987
-
Gilbertson R, Wickramasinghe C, Hernan R, et al: Clinical and molecular stratification of disease risk in medulloblastoma. Br J Cancer 85:705-712, 2001 (Pubitemid 32929469)
-
(2001)
British Journal of Cancer
, vol.85
, Issue.5
, pp. 705-712
-
-
Gilbertson, R.1
Wickramasinghe, C.2
Hernan, R.3
Balaji, V.4
Hunt, D.5
Jones-Wallace, D.6
Crolla, J.7
Perry, R.8
Lunec, J.9
Pearson, A.10
Ellison, D.11
-
29
-
-
0028918623
-
Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma
-
Gilbertson RJ, Pearson AD, Perry RH, et al: Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma. Br J Cancer 71:473-477, 1995
-
(1995)
Br J Cancer
, vol.71
, pp. 473-477
-
-
Gilbertson, R.J.1
Pearson, A.D.2
Perry, R.H.3
-
30
-
-
33751042197
-
Histopathological prognostic factors in medulloblastoma: High expression of survivin is related to unfavourable outcome
-
DOI 10.1016/j.ejca.2006.05.038, PII S0959804906006605
-
Haberler C, Slavc I, Czech T, et al: Histopathological prognostic factors in medulloblastoma: High expression of survivin is related to unfavourable outcome. Eur J Cancer 42:2996-3003, 2006 (Pubitemid 44755258)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.17
, pp. 2996-3003
-
-
Haberler, C.1
Slavc, I.2
Czech, T.3
Gelpi, E.4
Heinzl, H.5
Budka, H.6
Urban, C.7
Scarpatetti, M.8
Ebetsberger-Dachs, G.9
Schindler, C.10
Jones, N.11
Klein-Franke, A.12
Maier, H.13
Jauk, B.14
Kiefer, A.15
Hainfellner, J.A.16
-
31
-
-
0031425176
-
Potential prognostic value of C-erbB-2 expression in medulloblastomas in very young children
-
DOI 10.1097/00043426-199711000-00004
-
Herms JW, Behnke J, Bergmann M, et al: Potential prognostic value of C-erbB-2 expression in medulloblastomas in very young children. J Pediatr Hematol Oncol 19:510-515, 1997 (Pubitemid 28099081)
-
(1997)
Journal of Pediatric Hematology/Oncology
, vol.19
, Issue.6
, pp. 510-515
-
-
Herms, J.W.1
Behnke, J.2
Bergmann, M.3
Christen, H.-J.4
Kolb, R.5
Wilkening, M.6
Markakis, E.7
Hanefeld, F.8
Kretzschmar, H.A.9
-
32
-
-
42949114938
-
Discovery, in Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
-
DOI 10.1016/j.ccr.2008.03.004, PII S1535610808000895
-
Lain S, Hollick JJ, Campbell J, et al: Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell 13:454-463, 2008 (Pubitemid 351609441)
-
(2008)
Cancer Cell
, vol.13
, Issue.5
, pp. 454-463
-
-
Lain, S.1
Hollick, J.J.2
Campbell, J.3
Staples, O.D.4
Higgins, M.5
Aoubala, M.6
McCarthy, A.7
Appleyard, V.8
Murray, K.E.9
Baker, L.10
Thompson, A.11
Mathers, J.12
Holland, S.J.13
Stark, M.J.R.14
Pass, G.15
Woods, J.16
Lane, D.P.17
Westwood, N.J.18
-
33
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
DOI 10.1038/78638
-
Khuri FR, Nemunaitis J, Ganly I, et al: A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6:879-885, 2000 (Pubitemid 30644745)
-
(2000)
Nature Medicine
, vol.6
, Issue.8
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
Gore, M.7
Ironside, J.8
MacDougall, R.H.9
Heise, C.10
Randlev, B.11
Gillenwater, A.M.12
Bruso, P.13
Kaye, S.B.14
Hong, W.K.15
Kirn, D.H.16
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