-
1
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
2
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
34147095342
-
Protein composition of catalytically active human telomerase from immortal cells
-
Cohen SB, Graham ME, Lovrecz GO, Bache N, Robinson PJ, Reddel RR Protein composition of catalytically active human telomerase from immortal cells. Science 2007, 315:1850-1853.
-
(2007)
Science
, vol.315
, pp. 1850-1853
-
-
Cohen, S.B.1
Graham, M.E.2
Lovrecz, G.O.3
Bache, N.4
Robinson, P.J.5
Reddel, R.R.6
-
4
-
-
0037148401
-
Regulation of the human telomerase reverse transcriptase gene
-
Ducrest AL, Szutorisz H, Lingner J, Nabholz M Regulation of the human telomerase reverse transcriptase gene. Oncogene 2002, 21:541-552.
-
(2002)
Oncogene
, vol.21
, pp. 541-552
-
-
Ducrest, A.L.1
Szutorisz, H.2
Lingner, J.3
Nabholz, M.4
-
5
-
-
4644342289
-
Telomerase expression predicts unfavorable outcome in osteosarcoma
-
Sanders RP, Drissi R, Billups CA, Daw NC, Valentine MB, Dome JS Telomerase expression predicts unfavorable outcome in osteosarcoma. J Clin Oncol 2004, 22:3790-3797.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3790-3797
-
-
Sanders, R.P.1
Drissi, R.2
Billups, C.A.3
Daw, N.C.4
Valentine, M.B.5
Dome, J.S.6
-
6
-
-
33645741644
-
Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma
-
Tabori U, Ma J, Carter M, et al. Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma. J Clin Oncol 2006, 24:1522-1528.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1522-1528
-
-
Tabori, U.1
Ma, J.2
Carter, M.3
-
7
-
-
3042778750
-
Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma
-
Gertler R, Rosenberg R, Stricker D, et al. Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma. J Clin Oncol 2004, 22:1807-1814.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1807-1814
-
-
Gertler, R.1
Rosenberg, R.2
Stricker, D.3
-
8
-
-
84860389641
-
Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome
-
Lu L, Zhang C, Zhu G, et al. Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome. Breast Cancer Res 2011, 13:R56.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Lu, L.1
Zhang, C.2
Zhu, G.3
-
9
-
-
77954751638
-
Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival
-
McDonald KL, McDonnell J, Muntoni A, et al. Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival. J Neuropathol Exp Neurol 2010, 69:729-736.
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 729-736
-
-
McDonald, K.L.1
McDonnell, J.2
Muntoni, A.3
-
10
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu XY, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482:226-231.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
-
11
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 1997, 3:1271-1274.
-
(1997)
Nat Med
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
12
-
-
84868625787
-
Frequent ATRX, CIC, and FUBP1 mutations refine the classification of malignant gliomas
-
Jiao Y, Killela PJ, Reitman ZJ, et al. Frequent ATRX, CIC, and FUBP1 mutations refine the classification of malignant gliomas. Oncotarget 2012, 3:709-722.
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
-
13
-
-
0037426088
-
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
-
Hakin-Smith V, Jellinek DA, Levy D, et al. Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme. Lancet 2003, 361:836-838.
-
(2003)
Lancet
, vol.361
, pp. 836-838
-
-
Hakin-Smith, V.1
Jellinek, D.A.2
Levy, D.3
-
14
-
-
33746923402
-
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths
-
Wu YL, Dudognon C, Nguyen E, et al. Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths. J Cell Sci 2006, 119:2797-2806.
-
(2006)
J Cell Sci
, vol.119
, pp. 2797-2806
-
-
Wu, Y.L.1
Dudognon, C.2
Nguyen, E.3
-
15
-
-
0042169025
-
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms
-
Horikawa I, Barrett JC Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis 2003, 24:1167-1176.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1167-1176
-
-
Horikawa, I.1
Barrett, J.C.2
-
16
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001, 10:687-692.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
17
-
-
0033119780
-
DNA methylation and chromatin modification
-
Ng HH, Bird A DNA methylation and chromatin modification. Curr Opin Genet Dev 1999, 9:158-163.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 158-163
-
-
Ng, H.H.1
Bird, A.2
-
18
-
-
0242574736
-
Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes
-
Shin KH, Kang MK, Dicterow E, Park NH Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes. Br J Cancer 2003, 89:1473-1478.
-
(2003)
Br J Cancer
, vol.89
, pp. 1473-1478
-
-
Shin, K.H.1
Kang, M.K.2
Dicterow, E.3
Park, N.H.4
-
19
-
-
0033953573
-
Methylation of the human telomerase gene CpG island
-
Dessain SK, Yu H, Reddel RR, Beijersbergen RL, Weinberg RA Methylation of the human telomerase gene CpG island. Cancer Res 2000, 60:537-541.
-
(2000)
Cancer Res
, vol.60
, pp. 537-541
-
-
Dessain, S.K.1
Yu, H.2
Reddel, R.R.3
Beijersbergen, R.L.4
Weinberg, R.A.5
-
20
-
-
0036782079
-
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity
-
Guilleret I, Yan P, Grange F, Braunschweig R, Bosman FT, Benhattar J Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity. Int J Cancer 2002, 101:335-341.
-
(2002)
Int J Cancer
, vol.101
, pp. 335-341
-
-
Guilleret, I.1
Yan, P.2
Grange, F.3
Braunschweig, R.4
Bosman, F.T.5
Benhattar, J.6
-
21
-
-
0033572577
-
DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene
-
Devereux TR, Horikawa I, Anna CH, Annab LA, Afshari CA, Barrett JC DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene. Cancer Res 1999, 59:6087-6090.
-
(1999)
Cancer Res
, vol.59
, pp. 6087-6090
-
-
Devereux, T.R.1
Horikawa, I.2
Anna, C.H.3
Annab, L.A.4
Afshari, C.A.5
Barrett, J.C.6
-
23
-
-
0035117177
-
Wilms' tumor suppressor gene (WT1) is expressed in primary breast tumors despite tumor-specific promoter methylation
-
Loeb DM, Evron E, Patel CB, et al. Wilms' tumor suppressor gene (WT1) is expressed in primary breast tumors despite tumor-specific promoter methylation. Cancer Res 2001, 61:921-925.
-
(2001)
Cancer Res
, vol.61
, pp. 921-925
-
-
Loeb, D.M.1
Evron, E.2
Patel, C.B.3
-
24
-
-
84872395684
-
Regional activation of the cancer genome by long-range epigenetic remodeling
-
Bert SA, Robinson MD, Strbenac D, et al. Regional activation of the cancer genome by long-range epigenetic remodeling. Cancer Cell 2013, 23:9-22.
-
(2013)
Cancer Cell
, vol.23
, pp. 9-22
-
-
Bert, S.A.1
Robinson, M.D.2
Strbenac, D.3
-
25
-
-
33646427173
-
The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas
-
Tabori U, Vukovic B, Zielenska M, et al. The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas. Neoplasia 2006, 8:136-142.
-
(2006)
Neoplasia
, vol.8
, pp. 136-142
-
-
Tabori, U.1
Vukovic, B.2
Zielenska, M.3
-
26
-
-
53049110280
-
Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma
-
Tabori U, Wong V, Ma J, et al. Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma. Br J Cancer 2008, 99:1129-1135.
-
(2008)
Br J Cancer
, vol.99
, pp. 1129-1135
-
-
Tabori, U.1
Wong, V.2
Ma, J.3
-
27
-
-
78751515201
-
Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition
-
Castelo-Branco P, Zhang C, Lipman T, et al. Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition. Clin Cancer Res 2011, 17:111-121.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 111-121
-
-
Castelo-Branco, P.1
Zhang, C.2
Lipman, T.3
-
28
-
-
0033575114
-
Cancer surveillance series: recent trends in childhood cancer incidence and mortality in the United States
-
Linet MS, Ries LA, Smith MA, Tarone RE, Devesa SS Cancer surveillance series: recent trends in childhood cancer incidence and mortality in the United States. J Natl Cancer Inst 1999, 91:1051-1058.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1051-1058
-
-
Linet, M.S.1
Ries, L.A.2
Smith, M.A.3
Tarone, R.E.4
Devesa, S.S.5
-
29
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33:787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
30
-
-
79958754527
-
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
-
Sandoval J, Heyn H, Moran S, et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics 2011, 6:692-702.
-
(2011)
Epigenetics
, vol.6
, pp. 692-702
-
-
Sandoval, J.1
Heyn, H.2
Moran, S.3
-
31
-
-
35648937679
-
Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements
-
Coolen MW, Statham AL, Gardiner-Garden M, Clark SJ Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements. Nucleic Acids Res 2007, 35:e119.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Coolen, M.W.1
Statham, A.L.2
Gardiner-Garden, M.3
Clark, S.J.4
-
32
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
Heaphy CM, de Wilde RF, Jiao Y, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science 2011, 333:425.
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
de Wilde, R.F.2
Jiao, Y.3
-
33
-
-
56149086808
-
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma
-
Ridley L, Rahman R, Brundler MA, et al. Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro Oncol 2008, 10:675-689.
-
(2008)
Neuro Oncol
, vol.10
, pp. 675-689
-
-
Ridley, L.1
Rahman, R.2
Brundler, M.A.3
|