Acute intermittent porphyria causes hepatic mitochondrial energetic failure in a mouse model

International Journal of Biochemistry and Cell Biology

Volumn 51, Issue 1, 2014, Pages 93-101

  Homedan, Chadi ^a,b   Laafi, Jihane ^a   Schmitt, Caroline ^a,c,d   Gueguen, Naïg ^b,e   Lefebvre, Thibaud ^a,c,d   Karim, Zoubida ^a,c,d   Desquiret Dumas, Valérie ^b,e   Wetterwald, Céline ^b   Deybach, Jean Charles ^a,c,d   Gouya, Laurent ^a,c,d   Puy, Hervé ^a,c,d   Reynier, Pascal ^b,e   Malthièry, Yves ^a,b  

^a INSERM   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d Laboratory of Excellence   (France)

^e UNIVERSITÉ D'ANGERS   (France)

Author keywords

Acute intermittent porphyria; Hydroxymethylbilane synthase; Mitochondria; Oxidative phosphorylation; Tricarboxylic acid cycle

Indexed keywords

AMINOLEVULINIC ACID; CITRATE SYNTHASE; HEME ARGINATE; OXOGLUTARATE DEHYDROGENASE; PHENOBARBITAL; SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINYL COENZYME A; TRICARBOXYLIC ACID;

ACUTE INTERMITTENT PORPHYRIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEME SYNTHESIS; LIVER FAILURE; LIVER METABOLISM; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; RESPIRATORY CHAIN; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; ENERGY METABOLISM; LIVER DISEASES; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FEMALE; LIVER DISEASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; PORPHYRIA, ACUTE INTERMITTENT;

EID: 84899551356     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.03.032     Document Type: Article

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